JP6847660B2 - リガンドをコードする合成バイオマーカーのアフィニティベースの検出 - Google Patents

リガンドをコードする合成バイオマーカーのアフィニティベースの検出 Download PDF

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JP6847660B2
JP6847660B2 JP2016518043A JP2016518043A JP6847660B2 JP 6847660 B2 JP6847660 B2 JP 6847660B2 JP 2016518043 A JP2016518043 A JP 2016518043A JP 2016518043 A JP2016518043 A JP 2016518043A JP 6847660 B2 JP6847660 B2 JP 6847660B2
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enzyme
capture
detectable marker
ligand
detection
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JP2016520327A (ja
JP2016520327A5 (https=
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バティア，サンギータ，エヌ．
ウッド，デイビッド，ケー．
クウォン，ガブリエル，エー．
ウォーレン，アンドリュー，ディー．
リン，ケビン，ワイ．
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Massachusetts Institute of Technology
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/974—Thrombin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/22—Haematology
    • G01N2800/226—Thrombotic disorders, i.e. thrombo-embolism irrespective of location/organ involved, e.g. renal vein thrombosis, venous thrombosis

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  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
JP2016518043A 2013-06-07 2014-06-06 リガンドをコードする合成バイオマーカーのアフィニティベースの検出 Expired - Fee Related JP6847660B2 (ja)

Applications Claiming Priority (3)

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US201361832766P 2013-06-07 2013-06-07
US61/832,766 2013-06-07
PCT/US2014/041370 WO2014197840A1 (en) 2013-06-07 2014-06-06 Affinity-based detection of ligand-encoded synthetic biomarkers

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JP2019164018A Division JP7017544B2 (ja) 2013-06-07 2019-09-09 リガンドをコードする合成バイオマーカーのアフィニティベースの検出

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JP2016520327A JP2016520327A (ja) 2016-07-14
JP2016520327A5 JP2016520327A5 (https=) 2017-07-20
JP6847660B2 true JP6847660B2 (ja) 2021-03-24

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JP2016518043A Expired - Fee Related JP6847660B2 (ja) 2013-06-07 2014-06-06 リガンドをコードする合成バイオマーカーのアフィニティベースの検出
JP2019164018A Active JP7017544B2 (ja) 2013-06-07 2019-09-09 リガンドをコードする合成バイオマーカーのアフィニティベースの検出
JP2022010714A Active JP7368868B2 (ja) 2013-06-07 2022-01-27 リガンドをコードする合成バイオマーカーのアフィニティベースの検出

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JP2022010714A Active JP7368868B2 (ja) 2013-06-07 2022-01-27 リガンドをコードする合成バイオマーカーのアフィニティベースの検出

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US (2) US10527619B2 (https=)
EP (1) EP3004374B1 (https=)
JP (3) JP6847660B2 (https=)
CN (2) CN105452481A (https=)
CA (1) CA2914754A1 (https=)
ES (1) ES2828985T3 (https=)
WO (1) WO2014197840A1 (https=)

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