JP6824041B2 - ３つのタンパク質を補体成分に結合するための核酸化合物 - Google Patents

３つのタンパク質を補体成分に結合するための核酸化合物 Download PDF

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JP6824041B2
JP6824041B2 JP2016569420A JP2016569420A JP6824041B2 JP 6824041 B2 JP6824041 B2 JP 6824041B2 JP 2016569420 A JP2016569420 A JP 2016569420A JP 2016569420 A JP2016569420 A JP 2016569420A JP 6824041 B2 JP6824041 B2 JP 6824041B2
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deoxyuridine
methyluridine
fluorouridine
naphthylmethylcarboxyamide
aptamer
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JP2017517261A (ja
JP2017517261A5 (enExample
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ダニエル ダブリュー． ドロレ
ダニエル ダブリュー． ドロレ
チー チャン
チー チャン
ダニエル ジェイ． オコンネル
ダニエル ジェイ． オコンネル
シャシ グプタ
シャシ グプタ
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Somalogic Inc
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Somalogic Inc
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JP2016569420A 2014-05-30 2015-05-29 ３つのタンパク質を補体成分に結合するための核酸化合物 Expired - Fee Related JP6824041B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462005300P 2014-05-30 2014-05-30
US62/005,300 2014-05-30
PCT/US2015/033355 WO2015184372A1 (en) 2014-05-30 2015-05-29 Nucleic acid compounds for binding to complement component 3 protein

Publications (3)

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JP2017517261A JP2017517261A (ja) 2017-06-29
JP2017517261A5 JP2017517261A5 (enExample) 2019-03-14
JP6824041B2 true JP6824041B2 (ja) 2021-02-03

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JP2016569420A Expired - Fee Related JP6824041B2 (ja) 2014-05-30 2015-05-29 ３つのタンパク質を補体成分に結合するための核酸化合物

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US (2) US11466275B2 (enExample)
EP (1) EP3149173B1 (enExample)
JP (1) JP6824041B2 (enExample)
CN (2) CN106459979B (enExample)
CA (1) CA2949246C (enExample)
ES (1) ES2664179T3 (enExample)
NO (1) NO2718257T3 (enExample)
WO (1) WO2015184372A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES3013534T3 (en) * 2016-07-01 2025-04-14 Somalogic Operating Co Inc Oligonucleotides comprising modified nucleosides
US12202848B2 (en) * 2019-10-18 2025-01-21 Fujifilm Wako Pure Chemical Corporation Phosphoramidite activator

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6395888B1 (en) 1996-02-01 2002-05-28 Gilead Sciences, Inc. High affinity nucleic acid ligands of complement system proteins
US6140490A (en) 1996-02-01 2000-10-31 Nexstar Pharmaceuticals, Inc. High affinity nucleic acid ligands of complement system proteins
AU2994997A (en) * 1996-05-07 1997-11-26 T Cell Sciences, Inc. Aptamers for complement protein c3b
US20020082227A1 (en) * 1999-09-30 2002-06-27 Scott Henry Use of oligonucleotides for inhibition of complement activation
US20030219801A1 (en) * 2002-03-06 2003-11-27 Affymetrix, Inc. Aptamer base technique for ligand identification
SI1994171T1 (sl) * 2006-01-17 2015-07-31 Somalogic, Inc. Multipleksirane analize testnih vzorcev
US7947447B2 (en) * 2007-01-16 2011-05-24 Somalogic, Inc. Method for generating aptamers with improved off-rates
US8975026B2 (en) * 2007-01-16 2015-03-10 Somalogic, Inc. Method for generating aptamers with improved off-rates
US8927509B2 (en) * 2008-05-20 2015-01-06 The Research Foundation Of State University Of New York Aptamer modulators of complement protein C3 and biologically active proteolytic products thereof
EP2558586B1 (en) 2010-04-12 2016-10-12 Somalogic, Inc. APTAMERS TO ß-NGF AND THEIR USE IN TREATING ß-NGF MEDIATED DISEASES AND DISORDERS
ES2629183T3 (es) * 2011-03-10 2017-08-07 Somalogic, Inc. Aptámeros para diagnóstico de Clostridium difficile
CN104220453B (zh) 2012-04-03 2018-03-09 诺沃姆德治疗公司 人源化的嵌合抗因子c3抗体及其用途
US10975393B2 (en) * 2016-08-24 2021-04-13 Sangamo Therapeutics, Inc. Engineered target specific nucleases
PH12022550056A1 (en) * 2019-07-11 2023-04-12 Memorial Sloan Kettering Cancer Center Dll3-targeting antibodies and uses thereof

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Publication number Publication date
ES2664179T3 (es) 2018-04-18
CN106459979A (zh) 2017-02-22
CN106459979B (zh) 2020-07-21
CN110643610A (zh) 2020-01-03
US20230093170A1 (en) 2023-03-23
US20170166895A1 (en) 2017-06-15
CA2949246A1 (en) 2015-12-03
EP3149173A1 (en) 2017-04-05
WO2015184372A1 (en) 2015-12-03
NO2718257T3 (enExample) 2018-04-14
US11466275B2 (en) 2022-10-11
EP3149173B1 (en) 2018-02-07
CA2949246C (en) 2023-06-27
JP2017517261A (ja) 2017-06-29

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