CA2949246C - Nucleic acid compounds for binding to complement component 3 protein - Google Patents
Nucleic acid compounds for binding to complement component 3 protein Download PDFInfo
- Publication number
- CA2949246C CA2949246C CA2949246A CA2949246A CA2949246C CA 2949246 C CA2949246 C CA 2949246C CA 2949246 A CA2949246 A CA 2949246A CA 2949246 A CA2949246 A CA 2949246A CA 2949246 C CA2949246 C CA 2949246C
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- CA
- Canada
- Prior art keywords
- aptamer
- deoxyuridine
- protein
- seq
- fluorouridine
- Prior art date
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462005300P | 2014-05-30 | 2014-05-30 | |
| US62/005,300 | 2014-05-30 | ||
| PCT/US2015/033355 WO2015184372A1 (en) | 2014-05-30 | 2015-05-29 | Nucleic acid compounds for binding to complement component 3 protein |
Publications (2)
| Publication Number | Publication Date |
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| CA2949246A1 CA2949246A1 (en) | 2015-12-03 |
| CA2949246C true CA2949246C (en) | 2023-06-27 |
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| CA2949246A Active CA2949246C (en) | 2014-05-30 | 2015-05-29 | Nucleic acid compounds for binding to complement component 3 protein |
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| ES3013534T3 (en) * | 2016-07-01 | 2025-04-14 | Somalogic Operating Co Inc | Oligonucleotides comprising modified nucleosides |
| US12202848B2 (en) * | 2019-10-18 | 2025-01-21 | Fujifilm Wako Pure Chemical Corporation | Phosphoramidite activator |
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| US6395888B1 (en) | 1996-02-01 | 2002-05-28 | Gilead Sciences, Inc. | High affinity nucleic acid ligands of complement system proteins |
| US6140490A (en) | 1996-02-01 | 2000-10-31 | Nexstar Pharmaceuticals, Inc. | High affinity nucleic acid ligands of complement system proteins |
| AU2994997A (en) * | 1996-05-07 | 1997-11-26 | T Cell Sciences, Inc. | Aptamers for complement protein c3b |
| US20020082227A1 (en) * | 1999-09-30 | 2002-06-27 | Scott Henry | Use of oligonucleotides for inhibition of complement activation |
| US20030219801A1 (en) * | 2002-03-06 | 2003-11-27 | Affymetrix, Inc. | Aptamer base technique for ligand identification |
| SI1994171T1 (sl) * | 2006-01-17 | 2015-07-31 | Somalogic, Inc. | Multipleksirane analize testnih vzorcev |
| US7947447B2 (en) * | 2007-01-16 | 2011-05-24 | Somalogic, Inc. | Method for generating aptamers with improved off-rates |
| US8975026B2 (en) * | 2007-01-16 | 2015-03-10 | Somalogic, Inc. | Method for generating aptamers with improved off-rates |
| US8927509B2 (en) * | 2008-05-20 | 2015-01-06 | The Research Foundation Of State University Of New York | Aptamer modulators of complement protein C3 and biologically active proteolytic products thereof |
| EP2558586B1 (en) | 2010-04-12 | 2016-10-12 | Somalogic, Inc. | APTAMERS TO ß-NGF AND THEIR USE IN TREATING ß-NGF MEDIATED DISEASES AND DISORDERS |
| ES2629183T3 (es) * | 2011-03-10 | 2017-08-07 | Somalogic, Inc. | Aptámeros para diagnóstico de Clostridium difficile |
| CN104220453B (zh) | 2012-04-03 | 2018-03-09 | 诺沃姆德治疗公司 | 人源化的嵌合抗因子c3抗体及其用途 |
| US10975393B2 (en) * | 2016-08-24 | 2021-04-13 | Sangamo Therapeutics, Inc. | Engineered target specific nucleases |
| PH12022550056A1 (en) * | 2019-07-11 | 2023-04-12 | Memorial Sloan Kettering Cancer Center | Dll3-targeting antibodies and uses thereof |
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| CN106459979A (zh) | 2017-02-22 |
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