JP2017517261A5 - - Google Patents

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Publication number
JP2017517261A5
JP2017517261A5 JP2016569420A JP2016569420A JP2017517261A5 JP 2017517261 A5 JP2017517261 A5 JP 2017517261A5 JP 2016569420 A JP2016569420 A JP 2016569420A JP 2016569420 A JP2016569420 A JP 2016569420A JP 2017517261 A5 JP2017517261 A5 JP 2017517261A5
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JP
Japan
Prior art keywords
deoxyuridine
aptamer
protein
seq
methyluridine
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JP2016569420A
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English (en)
Japanese (ja)
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JP2017517261A (ja
JP6824041B2 (ja
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Priority claimed from PCT/US2015/033355 external-priority patent/WO2015184372A1/en
Publication of JP2017517261A publication Critical patent/JP2017517261A/ja
Publication of JP2017517261A5 publication Critical patent/JP2017517261A5/ja
Application granted granted Critical
Publication of JP6824041B2 publication Critical patent/JP6824041B2/ja
Expired - Fee Related legal-status Critical Current
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JP2016569420A 2014-05-30 2015-05-29 ３つのタンパク質を補体成分に結合するための核酸化合物 Expired - Fee Related JP6824041B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462005300P 2014-05-30 2014-05-30
US62/005,300 2014-05-30
PCT/US2015/033355 WO2015184372A1 (en) 2014-05-30 2015-05-29 Nucleic acid compounds for binding to complement component 3 protein

Publications (3)

Publication Number Publication Date
JP2017517261A JP2017517261A (ja) 2017-06-29
JP2017517261A5 true JP2017517261A5 (enExample) 2019-03-14
JP6824041B2 JP6824041B2 (ja) 2021-02-03

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ID=53398218

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016569420A Expired - Fee Related JP6824041B2 (ja) 2014-05-30 2015-05-29 ３つのタンパク質を補体成分に結合するための核酸化合物

Country Status (8)

Country Link
US (2) US11466275B2 (enExample)
EP (1) EP3149173B1 (enExample)
JP (1) JP6824041B2 (enExample)
CN (2) CN110643610A (enExample)
CA (1) CA2949246C (enExample)
ES (1) ES2664179T3 (enExample)
NO (1) NO2718257T3 (enExample)
WO (1) WO2015184372A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3478843B1 (en) * 2016-07-01 2021-08-04 Somalogic, Inc. Oligonucleotides comprising modified nucleosides
JP7452549B2 (ja) * 2019-10-18 2024-03-19 富士フイルム和光純薬株式会社 ホスホロアミダイト活性化剤

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6140490A (en) * 1996-02-01 2000-10-31 Nexstar Pharmaceuticals, Inc. High affinity nucleic acid ligands of complement system proteins
US6395888B1 (en) 1996-02-01 2002-05-28 Gilead Sciences, Inc. High affinity nucleic acid ligands of complement system proteins
WO1997042317A1 (en) 1996-05-07 1997-11-13 T Cell Sciences, Inc. APTAMERS FOR COMPLEMENT PROTEIN C3b
US20020082227A1 (en) * 1999-09-30 2002-06-27 Scott Henry Use of oligonucleotides for inhibition of complement activation
US20030219801A1 (en) * 2002-03-06 2003-11-27 Affymetrix, Inc. Aptamer base technique for ligand identification
EP2613147B1 (en) * 2006-01-17 2015-03-11 Somalogic, Inc. Detection methods using aptamers
US8975026B2 (en) * 2007-01-16 2015-03-10 Somalogic, Inc. Method for generating aptamers with improved off-rates
US7947447B2 (en) * 2007-01-16 2011-05-24 Somalogic, Inc. Method for generating aptamers with improved off-rates
US8927509B2 (en) * 2008-05-20 2015-01-06 The Research Foundation Of State University Of New York Aptamer modulators of complement protein C3 and biologically active proteolytic products thereof
AU2011240774B2 (en) 2010-04-12 2014-04-10 Otsuka Pharmaceutical Co., Ltd. Aptamers to beta-NGF and their use in treating beta-NGF mediated diseases and disorders
ES2629183T3 (es) * 2011-03-10 2017-08-07 Somalogic, Inc. Aptámeros para diagnóstico de Clostridium difficile
CN104220453B (zh) * 2012-04-03 2018-03-09 诺沃姆德治疗公司 人源化的嵌合抗因子c3抗体及其用途
IL300783B2 (en) * 2016-08-24 2026-03-01 Sangamo Therapeutics Inc Engineered nucleases with target-specific zinc fingers
BR112022000216A2 (pt) * 2019-07-11 2022-05-17 Memorial Sloan Kettering Cancer Center Anticorpos direcionados a dll3 e usos dos mesmos

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