JP2017517261A5 - - Google Patents

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Publication number
JP2017517261A5
JP2017517261A5 JP2016569420A JP2016569420A JP2017517261A5 JP 2017517261 A5 JP2017517261 A5 JP 2017517261A5 JP 2016569420 A JP2016569420 A JP 2016569420A JP 2016569420 A JP2016569420 A JP 2016569420A JP 2017517261 A5 JP2017517261 A5 JP 2017517261A5
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JP
Japan
Prior art keywords
deoxyuridine
aptamer
protein
seq
methyluridine
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JP2016569420A
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English (en)
Japanese (ja)
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JP2017517261A (ja
JP6824041B2 (ja
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Priority claimed from PCT/US2015/033355 external-priority patent/WO2015184372A1/en
Publication of JP2017517261A publication Critical patent/JP2017517261A/ja
Publication of JP2017517261A5 publication Critical patent/JP2017517261A5/ja
Application granted granted Critical
Publication of JP6824041B2 publication Critical patent/JP6824041B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2016569420A 2014-05-30 2015-05-29 3つのタンパク質を補体成分に結合するための核酸化合物 Expired - Fee Related JP6824041B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462005300P 2014-05-30 2014-05-30
US62/005,300 2014-05-30
PCT/US2015/033355 WO2015184372A1 (en) 2014-05-30 2015-05-29 Nucleic acid compounds for binding to complement component 3 protein

Publications (3)

Publication Number Publication Date
JP2017517261A JP2017517261A (ja) 2017-06-29
JP2017517261A5 true JP2017517261A5 (enExample) 2019-03-14
JP6824041B2 JP6824041B2 (ja) 2021-02-03

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ID=53398218

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016569420A Expired - Fee Related JP6824041B2 (ja) 2014-05-30 2015-05-29 3つのタンパク質を補体成分に結合するための核酸化合物

Country Status (8)

Country Link
US (2) US11466275B2 (enExample)
EP (1) EP3149173B1 (enExample)
JP (1) JP6824041B2 (enExample)
CN (2) CN106459979B (enExample)
CA (1) CA2949246C (enExample)
ES (1) ES2664179T3 (enExample)
NO (1) NO2718257T3 (enExample)
WO (1) WO2015184372A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10927380B2 (en) * 2016-07-01 2021-02-23 Somalogic, Inc. Oligonucleotides comprising modified nucleosides
US12202848B2 (en) * 2019-10-18 2025-01-21 Fujifilm Wako Pure Chemical Corporation Phosphoramidite activator

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6395888B1 (en) 1996-02-01 2002-05-28 Gilead Sciences, Inc. High affinity nucleic acid ligands of complement system proteins
US6140490A (en) * 1996-02-01 2000-10-31 Nexstar Pharmaceuticals, Inc. High affinity nucleic acid ligands of complement system proteins
WO1997042317A1 (en) * 1996-05-07 1997-11-13 T Cell Sciences, Inc. APTAMERS FOR COMPLEMENT PROTEIN C3b
US20020082227A1 (en) * 1999-09-30 2002-06-27 Scott Henry Use of oligonucleotides for inhibition of complement activation
US20030219801A1 (en) * 2002-03-06 2003-11-27 Affymetrix, Inc. Aptamer base technique for ligand identification
HUE025489T2 (en) * 2006-01-17 2016-04-28 Somalogic Inc Multiplexed analysis of test samples
US7947447B2 (en) * 2007-01-16 2011-05-24 Somalogic, Inc. Method for generating aptamers with improved off-rates
US8975026B2 (en) * 2007-01-16 2015-03-10 Somalogic, Inc. Method for generating aptamers with improved off-rates
US8927509B2 (en) * 2008-05-20 2015-01-06 The Research Foundation Of State University Of New York Aptamer modulators of complement protein C3 and biologically active proteolytic products thereof
NZ602618A (en) * 2010-04-12 2013-12-20 Somalogic Inc Aptamers to beta-ngf and their use in treating beta-ngf mediated diseases and disorders
WO2012122540A1 (en) * 2011-03-10 2012-09-13 Somalogic, Inc. Aptamers for clostridium difficile diagnostics
AU2013243574B2 (en) 2012-04-03 2017-12-07 Novelmed Therapeutics, Inc Humanized and chimeric anti-factor C3 antibodies and uses thereof
IL264792B2 (en) * 2016-08-24 2023-10-01 Sangamo Therapeutics Inc Engineered target-specific zinc-finger nucleases
US12441789B2 (en) * 2019-07-11 2025-10-14 Memorial Sloan Kettering Cancer Center DLL3-targeting antibodies and uses thereof

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