JP6811711B2 - 刺激性骨髄系細胞及び非刺激性骨髄系細胞の調節 - Google Patents

刺激性骨髄系細胞及び非刺激性骨髄系細胞の調節 Download PDF

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JP6811711B2
JP6811711B2 JP2017516664A JP2017516664A JP6811711B2 JP 6811711 B2 JP6811711 B2 JP 6811711B2 JP 2017516664 A JP2017516664 A JP 2017516664A JP 2017516664 A JP2017516664 A JP 2017516664A JP 6811711 B2 JP6811711 B2 JP 6811711B2
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antibody
myeloid cells
cells
cancer
antigen
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JP2017538664A (ja
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マシュー クランメル
マシュー クランメル
ミランダ ブロズ
ミランダ ブロズ
デニス ウォルフ
デニス ウォルフ
ジョシュア ポラック
ジョシュア ポラック
ミカイル ビンウィーズ
ミカイル ビンウィーズ
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University of California
University of California Los Angeles UCLA
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/243—Colony Stimulating Factors
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
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    • A61K40/41—Vertebrate antigens
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    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
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    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A61K2039/507—Comprising a combination of two or more separate antibodies
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    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/49—Breast
    • C—CHEMISTRY; METALLURGY
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    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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JP2017516664A 2014-09-28 2015-09-28 刺激性骨髄系細胞及び非刺激性骨髄系細胞の調節 Active JP6811711B2 (ja)

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US201462056569P 2014-09-28 2014-09-28
US62/056,569 2014-09-28
US201562129883P 2015-03-08 2015-03-08
US62/129,883 2015-03-08
PCT/US2015/052682 WO2016049641A1 (en) 2014-09-28 2015-09-28 Modulation of stimulatory and non-stimulatory myeloid cells

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JP2020207244A Active JP7168641B2 (ja) 2014-09-28 2020-12-15 刺激性骨髄系細胞及び非刺激性骨髄系細胞の調節
JP2022172033A Active JP7668257B2 (ja) 2014-09-28 2022-10-27 刺激性骨髄系細胞及び非刺激性骨髄系細胞の調節
JP2024205131A Pending JP2025027013A (ja) 2014-09-28 2024-11-26 刺激性骨髄系細胞及び非刺激性骨髄系細胞の調節

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JP2022172033A Active JP7668257B2 (ja) 2014-09-28 2022-10-27 刺激性骨髄系細胞及び非刺激性骨髄系細胞の調節
JP2024205131A Pending JP2025027013A (ja) 2014-09-28 2024-11-26 刺激性骨髄系細胞及び非刺激性骨髄系細胞の調節

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US (3) US10428143B2 (https=)
EP (1) EP3197495B1 (https=)
JP (4) JP6811711B2 (https=)
KR (3) KR102506663B1 (https=)
CN (1) CN106999585A (https=)
AU (3) AU2015319809B2 (https=)
CA (1) CA2961950A1 (https=)
EA (1) EA034921B1 (https=)
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MX (2) MX388410B (https=)
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