CA2961950A1 - Modulation of stimulatory and non-stimulatory myeloid cells - Google Patents

Modulation of stimulatory and non-stimulatory myeloid cells Download PDF

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Publication number
CA2961950A1
CA2961950A1 CA2961950A CA2961950A CA2961950A1 CA 2961950 A1 CA2961950 A1 CA 2961950A1 CA 2961950 A CA2961950 A CA 2961950A CA 2961950 A CA2961950 A CA 2961950A CA 2961950 A1 CA2961950 A1 CA 2961950A1
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Prior art keywords
myeloid cells
stimulatory myeloid
cells
antibody
tumor
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CA2961950A
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English (en)
French (fr)
Inventor
Matthew Krummel
Miranda BROZ
Denise WOLF
Joshua Pollack
Mikhail BINNEWIES
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University of California San Diego UCSD
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University of California San Diego UCSD
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/4224—Molecules with a "CD" designation not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/243—Colony Stimulating Factors
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07—ORGANIC CHEMISTRY
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    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • A—HUMAN NECESSITIES
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    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
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CA2961950A 2014-09-28 2015-09-28 Modulation of stimulatory and non-stimulatory myeloid cells Pending CA2961950A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462056569P 2014-09-28 2014-09-28
US62/056,569 2014-09-28
US201562129883P 2015-03-08 2015-03-08
US62/129,883 2015-03-08
PCT/US2015/052682 WO2016049641A1 (en) 2014-09-28 2015-09-28 Modulation of stimulatory and non-stimulatory myeloid cells

Publications (1)

Publication Number Publication Date
CA2961950A1 true CA2961950A1 (en) 2016-03-31

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CA2961950A Pending CA2961950A1 (en) 2014-09-28 2015-09-28 Modulation of stimulatory and non-stimulatory myeloid cells

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US (3) US10428143B2 (https=)
EP (1) EP3197495B1 (https=)
JP (4) JP6811711B2 (https=)
KR (3) KR102506663B1 (https=)
CN (1) CN106999585A (https=)
AU (3) AU2015319809B2 (https=)
CA (1) CA2961950A1 (https=)
EA (1) EA034921B1 (https=)
IL (4) IL312777A (https=)
MX (2) MX388410B (https=)
WO (1) WO2016049641A1 (https=)
ZA (1) ZA201701658B (https=)

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