JP6773672B2 - フルオロケトライドを調製するための方法 - Google Patents
フルオロケトライドを調製するための方法 Download PDFInfo
- Publication number
- JP6773672B2 JP6773672B2 JP2017546856A JP2017546856A JP6773672B2 JP 6773672 B2 JP6773672 B2 JP 6773672B2 JP 2017546856 A JP2017546856 A JP 2017546856A JP 2017546856 A JP2017546856 A JP 2017546856A JP 6773672 B2 JP6773672 B2 JP 6773672B2
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- formula
- compound
- alkyl
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 0 CC[C@@](*C[C@@](C([C@](C)C([C@](C)[C@]([C@](C)(CC(C)C)OC)O[C@@]([C@]1O*)O[C@](C)C[C@@]1NC)=O)=O)F)[C@@](C)(*)[C@@]([C@@](C)C(C)C)F Chemical compound CC[C@@](*C[C@@](C([C@](C)C([C@](C)[C@]([C@](C)(CC(C)C)OC)O[C@@]([C@]1O*)O[C@](C)C[C@@]1NC)=O)=O)F)[C@@](C)(*)[C@@]([C@@](C)C(C)C)F 0.000 description 10
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562129305P | 2015-03-06 | 2015-03-06 | |
| US62/129,305 | 2015-03-06 | ||
| PCT/US2016/021085 WO2016144833A1 (en) | 2015-03-06 | 2016-03-05 | Processes for preparing fluoroketolides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018508537A JP2018508537A (ja) | 2018-03-29 |
| JP2018508537A5 JP2018508537A5 (enExample) | 2019-04-18 |
| JP6773672B2 true JP6773672B2 (ja) | 2020-10-21 |
Family
ID=56880477
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017546856A Active JP6773672B2 (ja) | 2015-03-06 | 2016-03-05 | フルオロケトライドを調製するための方法 |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US20180044365A1 (enExample) |
| EP (1) | EP3265100A4 (enExample) |
| JP (1) | JP6773672B2 (enExample) |
| KR (1) | KR20170133377A (enExample) |
| CN (1) | CN107405355A (enExample) |
| AU (1) | AU2016230027A1 (enExample) |
| BR (1) | BR112017019176A2 (enExample) |
| CA (1) | CA2978731A1 (enExample) |
| CL (1) | CL2017002255A1 (enExample) |
| CO (1) | CO2017010143A2 (enExample) |
| HK (1) | HK1247097A1 (enExample) |
| IL (1) | IL254306A0 (enExample) |
| MX (2) | MX2017011454A (enExample) |
| PE (1) | PE20180219A1 (enExample) |
| RU (1) | RU2017131253A (enExample) |
| SG (2) | SG11201707215XA (enExample) |
| TW (1) | TW201638102A (enExample) |
| WO (1) | WO2016144833A1 (enExample) |
| ZA (1) | ZA201706505B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101917850B (zh) | 2007-10-25 | 2016-01-13 | 森普拉制药公司 | 大环内酯类抗菌剂的制备方法 |
| DK2358379T3 (en) | 2008-10-24 | 2016-03-07 | Cempra Pharmaceuticals Inc | BIOFORSVAR USING TRIAZOLHOLDIGE macrolides |
| US9937194B1 (en) | 2009-06-12 | 2018-04-10 | Cempra Pharmaceuticals, Inc. | Compounds and methods for treating inflammatory diseases |
| MX2014011537A (es) | 2012-03-27 | 2015-02-10 | Cempra Pharmaceuticals Inc | Formulaciones parenterales para la administracion de antibioticos macrolidos. |
| WO2014152326A1 (en) | 2013-03-14 | 2014-09-25 | Cempra Pharmaceuticals, Inc. | Methods for treating respiratory diseases and formulations therefor |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3668282A (en) * | 1970-05-08 | 1972-06-06 | Stauffer Chemical Co | Stabilized mixture employing n-(beta-0,0-dialkyldithiophosphoryl) aryl sulfonamides |
| EP3738591A3 (en) * | 2003-03-10 | 2021-03-24 | Merck Sharp & Dohme Corp. | Novel antibacterial agents |
| US7595300B2 (en) * | 2005-12-13 | 2009-09-29 | Kosan Biosciences Incorporated | 7-quinolyl ketolide antibacterial agents |
| CN101917850B (zh) * | 2007-10-25 | 2016-01-13 | 森普拉制药公司 | 大环内酯类抗菌剂的制备方法 |
| US8376805B2 (en) * | 2008-07-24 | 2013-02-19 | Ideo Llc | Printable pre-sewn stuffed toy composite sheets |
| KR101567658B1 (ko) * | 2011-03-01 | 2015-11-09 | 욱크하르트 리미티드 | 케톨리드 중간체의 제조 방법 |
| WO2014152326A1 (en) * | 2013-03-14 | 2014-09-25 | Cempra Pharmaceuticals, Inc. | Methods for treating respiratory diseases and formulations therefor |
| BR112015023670A2 (pt) * | 2013-03-15 | 2017-07-18 | Cempra Pharmaceuticals Inc | processo para preparar um composto |
| BR112015025159A2 (pt) * | 2013-04-04 | 2017-07-18 | Harvard College | macrolídeos e métodos de sua preparação e uso |
-
2016
- 2016-03-05 US US15/555,701 patent/US20180044365A1/en not_active Abandoned
- 2016-03-05 BR BR112017019176A patent/BR112017019176A2/pt not_active Application Discontinuation
- 2016-03-05 JP JP2017546856A patent/JP6773672B2/ja active Active
- 2016-03-05 EP EP16762268.7A patent/EP3265100A4/en not_active Withdrawn
- 2016-03-05 WO PCT/US2016/021085 patent/WO2016144833A1/en not_active Ceased
- 2016-03-05 PE PE2017001500A patent/PE20180219A1/es not_active Application Discontinuation
- 2016-03-05 SG SG11201707215XA patent/SG11201707215XA/en unknown
- 2016-03-05 KR KR1020177028547A patent/KR20170133377A/ko not_active Withdrawn
- 2016-03-05 MX MX2017011454A patent/MX2017011454A/es unknown
- 2016-03-05 CA CA2978731A patent/CA2978731A1/en not_active Abandoned
- 2016-03-05 RU RU2017131253A patent/RU2017131253A/ru unknown
- 2016-03-05 AU AU2016230027A patent/AU2016230027A1/en not_active Abandoned
- 2016-03-05 SG SG10201908248P patent/SG10201908248PA/en unknown
- 2016-03-05 CN CN201680021207.4A patent/CN107405355A/zh active Pending
- 2016-03-05 HK HK18106628.7A patent/HK1247097A1/zh unknown
- 2016-03-07 TW TW105106986A patent/TW201638102A/zh unknown
-
2017
- 2017-09-04 IL IL254306A patent/IL254306A0/en unknown
- 2017-09-06 MX MX2020007742A patent/MX2020007742A/es unknown
- 2017-09-06 CL CL2017002255A patent/CL2017002255A1/es unknown
- 2017-09-27 ZA ZA2017/06505A patent/ZA201706505B/en unknown
- 2017-10-05 CO CONC2017/0010143A patent/CO2017010143A2/es unknown
-
2020
- 2020-04-23 US US16/856,754 patent/US20210070797A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ZA201706505B (en) | 2021-04-28 |
| RU2017131253A (ru) | 2019-04-08 |
| KR20170133377A (ko) | 2017-12-05 |
| PE20180219A1 (es) | 2018-01-31 |
| MX2017011454A (es) | 2018-01-23 |
| IL254306A0 (en) | 2017-11-30 |
| EP3265100A1 (en) | 2018-01-10 |
| CL2017002255A1 (es) | 2018-05-11 |
| HK1247097A1 (zh) | 2018-09-21 |
| CA2978731A1 (en) | 2016-09-15 |
| US20180044365A1 (en) | 2018-02-15 |
| JP2018508537A (ja) | 2018-03-29 |
| CN107405355A (zh) | 2017-11-28 |
| SG10201908248PA (en) | 2019-10-30 |
| MX2020007742A (es) | 2020-09-25 |
| CO2017010143A2 (es) | 2018-02-28 |
| BR112017019176A2 (pt) | 2018-04-24 |
| US20210070797A1 (en) | 2021-03-11 |
| AU2016230027A1 (en) | 2017-09-28 |
| TW201638102A (zh) | 2016-11-01 |
| SG11201707215XA (en) | 2017-10-30 |
| EP3265100A4 (en) | 2019-01-09 |
| WO2016144833A1 (en) | 2016-09-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6773672B2 (ja) | フルオロケトライドを調製するための方法 | |
| US10947183B2 (en) | Fenfluramine compositions and methods of preparing the same | |
| US8859522B2 (en) | Processes for the preparation of regadenoson and a new crystalline form thereof | |
| CN101506220B (zh) | 大环内酯合成方法 | |
| CN107428791A (zh) | 烟酰胺核苷的结晶形式 | |
| JP6215399B2 (ja) | ナルトレキソンの製造方法 | |
| WO2018045294A1 (en) | Processes for preparing fluoroketolides | |
| TWI397534B (zh) | 大環內酯合成方法 | |
| US20090076040A1 (en) | Deuterium-enriched valganciclovir | |
| US20090075965A1 (en) | Deuterium-enriched amoxicilin | |
| US20080306105A1 (en) | Deuterium-enriched moxifloxacin | |
| US20090076165A1 (en) | Deuterium-enriched memantine | |
| US20090076164A1 (en) | Deuterium-enriched tapentadol | |
| US20090075966A1 (en) | Deuterium-enriched tazobactam | |
| US20090062182A1 (en) | Deuterium-enriched dalbavancin | |
| WO2022119928A1 (en) | Imidazole compounds as inhibitors of enpp1 | |
| US20090062220A1 (en) | Deuterium-enriched azithromycin | |
| US20090075917A1 (en) | Deuterium-enriched telithromycin | |
| US20120122833A1 (en) | Deuterium-enriched meropenem | |
| US20090076082A1 (en) | Deuterium-enriched alvimopan | |
| US20090062393A1 (en) | Deuterium-enriched pregabalin |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20190305 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20190305 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20200114 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20200413 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20200612 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20200714 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20200901 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20201001 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 6773672 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |