KR20170133377A - 플루오로케톨라이드의 제조 방법 - Google Patents
플루오로케톨라이드의 제조 방법 Download PDFInfo
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- KR20170133377A KR20170133377A KR1020177028547A KR20177028547A KR20170133377A KR 20170133377 A KR20170133377 A KR 20170133377A KR 1020177028547 A KR1020177028547 A KR 1020177028547A KR 20177028547 A KR20177028547 A KR 20177028547A KR 20170133377 A KR20170133377 A KR 20170133377A
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- Prior art keywords
- compound
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- derivative
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- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 24
- 125000002252 acyl group Chemical group 0.000 claims description 20
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- 239000001257 hydrogen Substances 0.000 claims description 17
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 16
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 16
- 125000004432 carbon atom Chemical group C* 0.000 claims description 14
- 229910052760 oxygen Inorganic materials 0.000 claims description 14
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- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 3
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- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 description 2
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- 125000005094 alkyl carbonyl amino alkyl group Chemical group 0.000 description 2
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Pyrane Compounds (AREA)
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| US201562129305P | 2015-03-06 | 2015-03-06 | |
| US62/129,305 | 2015-03-06 | ||
| PCT/US2016/021085 WO2016144833A1 (en) | 2015-03-06 | 2016-03-05 | Processes for preparing fluoroketolides |
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| KR20170133377A true KR20170133377A (ko) | 2017-12-05 |
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| AU (1) | AU2016230027A1 (enExample) |
| BR (1) | BR112017019176A2 (enExample) |
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| CO (1) | CO2017010143A2 (enExample) |
| HK (1) | HK1247097A1 (enExample) |
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| TW (1) | TW201638102A (enExample) |
| WO (1) | WO2016144833A1 (enExample) |
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| AU2008316830B2 (en) | 2007-10-25 | 2016-03-17 | Cempra Pharmaceuticals, Inc. | Process for the preparation of macrolide antibacterial agents |
| CN107854477A (zh) | 2008-10-24 | 2018-03-30 | 森普拉制药公司 | 使用含三唑的大环内酯治疗抗性疾病的方法 |
| US9937194B1 (en) | 2009-06-12 | 2018-04-10 | Cempra Pharmaceuticals, Inc. | Compounds and methods for treating inflammatory diseases |
| WO2013148891A1 (en) | 2012-03-27 | 2013-10-03 | Cempra Pharmaceuticals, Inc. | Parenteral formulations for administering macrolide antibiotics |
| WO2014152326A1 (en) | 2013-03-14 | 2014-09-25 | Cempra Pharmaceuticals, Inc. | Methods for treating respiratory diseases and formulations therefor |
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| US3668282A (en) * | 1970-05-08 | 1972-06-06 | Stauffer Chemical Co | Stabilized mixture employing n-(beta-0,0-dialkyldithiophosphoryl) aryl sulfonamides |
| US7601695B2 (en) * | 2003-03-10 | 2009-10-13 | Optimer Pharmaceuticals, Inc. | Antibacterial agents |
| US7595300B2 (en) * | 2005-12-13 | 2009-09-29 | Kosan Biosciences Incorporated | 7-quinolyl ketolide antibacterial agents |
| AU2008316830B2 (en) * | 2007-10-25 | 2016-03-17 | Cempra Pharmaceuticals, Inc. | Process for the preparation of macrolide antibacterial agents |
| US8376805B2 (en) * | 2008-07-24 | 2013-02-19 | Ideo Llc | Printable pre-sewn stuffed toy composite sheets |
| CN103619849B (zh) * | 2011-03-01 | 2016-05-25 | 沃克哈特有限公司 | 酮内酯中间体的制备方法 |
| WO2014152326A1 (en) * | 2013-03-14 | 2014-09-25 | Cempra Pharmaceuticals, Inc. | Methods for treating respiratory diseases and formulations therefor |
| AU2014233240B2 (en) * | 2013-03-15 | 2018-08-09 | Cempra Pharmaceuticals, Inc. | Convergent processes for preparing macrolide antibacterial agents |
| EP4095146A1 (en) * | 2013-04-04 | 2022-11-30 | President And Fellows Of Harvard College | Macrolides and methods of their preparation and use |
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- 2016-03-05 BR BR112017019176A patent/BR112017019176A2/pt not_active Application Discontinuation
- 2016-03-05 SG SG11201707215XA patent/SG11201707215XA/en unknown
- 2016-03-05 WO PCT/US2016/021085 patent/WO2016144833A1/en not_active Ceased
- 2016-03-05 KR KR1020177028547A patent/KR20170133377A/ko not_active Withdrawn
- 2016-03-05 US US15/555,701 patent/US20180044365A1/en not_active Abandoned
- 2016-03-05 AU AU2016230027A patent/AU2016230027A1/en not_active Abandoned
- 2016-03-05 CA CA2978731A patent/CA2978731A1/en not_active Abandoned
- 2016-03-05 EP EP16762268.7A patent/EP3265100A4/en not_active Withdrawn
- 2016-03-07 TW TW105106986A patent/TW201638102A/zh unknown
-
2017
- 2017-09-04 IL IL254306A patent/IL254306A0/en unknown
- 2017-09-06 MX MX2020007742A patent/MX2020007742A/es unknown
- 2017-09-06 CL CL2017002255A patent/CL2017002255A1/es unknown
- 2017-09-27 ZA ZA2017/06505A patent/ZA201706505B/en unknown
- 2017-10-05 CO CONC2017/0010143A patent/CO2017010143A2/es unknown
-
2020
- 2020-04-23 US US16/856,754 patent/US20210070797A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2978731A1 (en) | 2016-09-15 |
| JP6773672B2 (ja) | 2020-10-21 |
| WO2016144833A1 (en) | 2016-09-15 |
| CN107405355A (zh) | 2017-11-28 |
| CO2017010143A2 (es) | 2018-02-28 |
| US20210070797A1 (en) | 2021-03-11 |
| HK1247097A1 (zh) | 2018-09-21 |
| BR112017019176A2 (pt) | 2018-04-24 |
| TW201638102A (zh) | 2016-11-01 |
| US20180044365A1 (en) | 2018-02-15 |
| AU2016230027A1 (en) | 2017-09-28 |
| CL2017002255A1 (es) | 2018-05-11 |
| EP3265100A4 (en) | 2019-01-09 |
| EP3265100A1 (en) | 2018-01-10 |
| MX2017011454A (es) | 2018-01-23 |
| SG11201707215XA (en) | 2017-10-30 |
| JP2018508537A (ja) | 2018-03-29 |
| IL254306A0 (en) | 2017-11-30 |
| PE20180219A1 (es) | 2018-01-31 |
| MX2020007742A (es) | 2020-09-25 |
| SG10201908248PA (en) | 2019-10-30 |
| ZA201706505B (en) | 2021-04-28 |
| RU2017131253A (ru) | 2019-04-08 |
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