JP6745220B2 - 骨髄性悪性腫瘍の診断のための突然変異体カルレチクリン - Google Patents

骨髄性悪性腫瘍の診断のための突然変異体カルレチクリン Download PDF

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JP6745220B2
JP6745220B2 JP2016542333A JP2016542333A JP6745220B2 JP 6745220 B2 JP6745220 B2 JP 6745220B2 JP 2016542333 A JP2016542333 A JP 2016542333A JP 2016542333 A JP2016542333 A JP 2016542333A JP 6745220 B2 JP6745220 B2 JP 6745220B2
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nucleic acid
protein
seq
calreticulin
mutant
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JP2016537012A (ja
JP2016537012A5 (OSRAM
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クラロヴィクス，ロバート
クランプフル，ソーステン
ギスリンガー，ハインツ
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ツェーエムエム−フォルシュングスツェントルム フュア モレクラレ メディツィン ゲーエムベーハー
ツェーエムエム−フォルシュングスツェントルム フュア モレクラレ メディツィン ゲーエムベーハー
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4728—Calcium binding proteins, e.g. calmodulin
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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    • C12Q2600/00—Oligonucleotides characterized by their use
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    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4727—Calcium binding proteins, e.g. calmodulin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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JP2016542333A 2013-09-16 2014-09-15 骨髄性悪性腫瘍の診断のための突然変異体カルレチクリン Active JP6745220B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP13184632 2013-09-16
EP13184632.1 2013-09-16
EP13186939.8 2013-10-01
EP13186939 2013-10-01
US201361909313P 2013-11-26 2013-11-26
US61/909,313 2013-11-26
PCT/EP2014/069638 WO2015036599A1 (en) 2013-09-16 2014-09-15 Mutant calreticulin for the diagnosis of myeloid malignancies

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JP2020022378A Division JP2020109092A (ja) 2013-09-16 2020-02-13 骨髄性悪性腫瘍の診断のための突然変異体カルレチクリン

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JP2016537012A JP2016537012A (ja) 2016-12-01
JP2016537012A5 JP2016537012A5 (OSRAM) 2017-11-02
JP6745220B2 true JP6745220B2 (ja) 2020-08-26

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JP2022177306A Active JP7646221B2 (ja) 2013-09-16 2022-11-04 骨髄性悪性腫瘍の診断のための突然変異体カルレチクリン

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US (5) US9371570B2 (OSRAM)
EP (4) EP3494985B1 (OSRAM)
JP (2) JP6745220B2 (OSRAM)
KR (1) KR102433548B1 (OSRAM)
CN (2) CN113564254A (OSRAM)
AU (2) AU2014320262B2 (OSRAM)
BR (1) BR112016005611B1 (OSRAM)
CA (1) CA2924370C (OSRAM)
DK (3) DK3494985T3 (OSRAM)
ES (1) ES2577289T3 (OSRAM)
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PL (2) PL3494985T3 (OSRAM)
PT (1) PT2808338E (OSRAM)
RU (1) RU2668808C2 (OSRAM)
SG (1) SG11201601193TA (OSRAM)
WO (1) WO2015036599A1 (OSRAM)

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