JP6735277B2 - 乳癌療法剤に対する反応を予測するための方法および乳癌の処置の方法 - Google Patents

乳癌療法剤に対する反応を予測するための方法および乳癌の処置の方法 Download PDF

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JP6735277B2
JP6735277B2 JP2017531209A JP2017531209A JP6735277B2 JP 6735277 B2 JP6735277 B2 JP 6735277B2 JP 2017531209 A JP2017531209 A JP 2017531209A JP 2017531209 A JP2017531209 A JP 2017531209A JP 6735277 B2 JP6735277 B2 JP 6735277B2
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JP2018504892A (ja
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ピーターソン,エイミー・クリスチャン
アパル,ヒルデシュ
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メディベイション プロステイト セラピューティクス エルエルシー
メディベイション プロステイト セラピューティクス エルエルシー
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
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    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Health & Medical Sciences (AREA)
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  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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JP2017531209A 2014-12-12 2015-12-08 乳癌療法剤に対する反応を予測するための方法および乳癌の処置の方法 Expired - Fee Related JP6735277B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201462091195P 2014-12-12 2014-12-12
US62/091,195 2014-12-12
US201562142504P 2015-04-03 2015-04-03
US62/142,504 2015-04-03
US201562167110P 2015-05-27 2015-05-27
US62/167,110 2015-05-27
PCT/US2015/064500 WO2016094408A1 (en) 2014-12-12 2015-12-08 Method for predicting response to breast cancer therapeutic agents and method of treatment of breast cancer

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JP2018504892A JP2018504892A (ja) 2018-02-22
JP2018504892A5 JP2018504892A5 (enExample) 2019-01-24
JP6735277B2 true JP6735277B2 (ja) 2020-08-05

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US (3) US10196693B2 (enExample)
EP (2) EP3604556A1 (enExample)
JP (1) JP6735277B2 (enExample)
KR (1) KR20170095306A (enExample)
CN (1) CN107109488A (enExample)
AU (1) AU2015360767A1 (enExample)
BR (1) BR112017012142A2 (enExample)
CA (1) CA2970469A1 (enExample)
ES (1) ES2748005T3 (enExample)
IL (1) IL252587A0 (enExample)
MX (1) MX2017007707A (enExample)
RU (1) RU2017120330A (enExample)
SG (1) SG11201704425TA (enExample)
WO (1) WO2016094408A1 (enExample)
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CN109735625A (zh) * 2019-03-18 2019-05-10 马榕 乳头溢液在检测肿瘤相关基因中的应用
CN114334000B (zh) * 2021-12-28 2025-07-25 上海中医药大学 基于转录组图谱的组合药物生成方法、系统及存储介质
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US10196693B2 (en) 2019-02-05
US20160168646A1 (en) 2016-06-16
US11952634B2 (en) 2024-04-09
BR112017012142A2 (pt) 2018-01-02
CN107109488A (zh) 2017-08-29
US20190169697A1 (en) 2019-06-06
SG11201704425TA (en) 2017-06-29
KR20170095306A (ko) 2017-08-22
EP3604556A1 (en) 2020-02-05
WO2016094408A1 (en) 2016-06-16
IL252587A0 (en) 2017-07-31
ZA201703904B (en) 2019-12-18
EP3230471B1 (en) 2019-08-28
US11186876B2 (en) 2021-11-30
US20220056541A1 (en) 2022-02-24
JP2018504892A (ja) 2018-02-22
AU2015360767A1 (en) 2017-06-08
RU2017120330A (ru) 2019-01-14
EP3230471A1 (en) 2017-10-18
MX2017007707A (es) 2018-03-06
CA2970469A1 (en) 2016-06-16
RU2017120330A3 (enExample) 2019-07-24
ES2748005T3 (es) 2020-03-12

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