JP6731216B2 - 検体用ホルダ - Google Patents
検体用ホルダ Download PDFInfo
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- JP6731216B2 JP6731216B2 JP2014217689A JP2014217689A JP6731216B2 JP 6731216 B2 JP6731216 B2 JP 6731216B2 JP 2014217689 A JP2014217689 A JP 2014217689A JP 2014217689 A JP2014217689 A JP 2014217689A JP 6731216 B2 JP6731216 B2 JP 6731216B2
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Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Optical Measuring Cells (AREA)
Description
前記検体を収容する収容部と、
前記検体用ホルダの外側から射出された前記励起光を透過させて前記収容部に収容された前記検体に当該励起光を照射させるための窓部とを有し、
少なくとも前記窓部が低自家蛍光性材料で構成されていることを特徴とする。
検体用ホルダの説明に先駆けて、このホルダを利用する腫瘍部位識別装置の構成について説明する。
次に、ホルダ1の構成について説明する。図4Aはホルダ1の斜視図の一例である。図4Aに示すように、ホルダ1は、基体部42と蓋部43を含んで構成されている。図4Bは基体部42の平面図の一例であり、図4Cは蓋部43の平面図の一例である。
以下において、別実施形態について説明する。
2 : 検体
10 : 腫瘍部位識別装置
11 : ホルダ装着口
12 : 表示部
21 : 光源部
22 : フィルタ
23 : ダイクロイックミラー
24 : 対物レンズ
25 : フィルタ
26 : 受光部
27 : 演算処理部
31 : 励起光
32 : 蛍光
41 : 収容部
42 : 基体部
43 : 蓋部
51 : ヒンジ部
52 : 窓部
61 : 封止部材(シール部)
Claims (8)
- 光源部から射出される励起光を検体に照射し、前記検体の腫瘍部位に存在するポルフィリン類が発する蛍光を分光して検出することで、前記腫瘍部位と非腫瘍部位の識別を行う腫瘍部位識別装置に使用される検体用ホルダであって、
基体部と、
前記基体部に対してヒンジ部によって連結され、前記基体部に対して回転可能に構成された蓋部と、
前記基体部のうち、周囲よりも深さが深い箇所に形成され、前記検体を収容する収容部と、
前記検体用ホルダの外側から射出された前記励起光を透過させて前記収容部に収容された前記検体に当該励起光を照射させるための窓部とを有し、
少なくとも前記窓部が低自家蛍光性材料で構成されていることを特徴とする検体用ホルダ。 - 前記窓部が、芳香族ポリカーボネート樹脂、ポリスチレン樹脂、環状オレフィン系樹脂、又はアクリル系樹脂のいずれか一又は複数で構成されていることを特徴とする請求項1に記載の検体用ホルダ。
- 前記窓部が、波長370nm以上の光に対する光透過率が80%以上の材料で構成されていることを特徴とする請求項1又は2に記載の検体用ホルダ。
- 前記蓋部又は前記基体部の少なくとも一方には封止部材が設けられており、
前記蓋部を閉じると、前記封止部材を介して前記蓋部と前記基体部が接触し、前記収容部が密閉されることを特徴とする請求項1〜3のいずれか1項に記載の検体用ホルダ。 - 前記ポルフィリン類がプロトポルフィリン類であることを特徴とする請求項1〜4のいずれか1項に記載の検体用ホルダ。
- 前記プロトポルフィリン類はプロトポルフィリンIXであることを特徴とする請求項5に記載の検体用ホルダ。
- 1つの前記収容部を有することを特徴とする、請求項1〜6のいずれか1項に記載の検体用ホルダ。
- 前記基体部及び前記蓋部が、芳香族ポリカーボネート樹脂、ポリスチレン樹脂、環状オレフィン系樹脂、又はアクリル系樹脂のいずれか一又は複数で構成されていることを特徴とする、請求項1〜7のいずれか1項に記載の検体用ホルダ。
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2014217689A JP6731216B2 (ja) | 2014-10-24 | 2014-10-24 | 検体用ホルダ |
CN201580057473.8A CN107110768B (zh) | 2014-10-24 | 2015-10-22 | 试样用夹持器 |
PCT/JP2015/079831 WO2016063950A1 (ja) | 2014-10-24 | 2015-10-22 | 検体用ホルダ |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2014217689A JP6731216B2 (ja) | 2014-10-24 | 2014-10-24 | 検体用ホルダ |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2016085108A JP2016085108A (ja) | 2016-05-19 |
JP6731216B2 true JP6731216B2 (ja) | 2020-07-29 |
Family
ID=55760980
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014217689A Active JP6731216B2 (ja) | 2014-10-24 | 2014-10-24 | 検体用ホルダ |
Country Status (3)
Country | Link |
---|---|
JP (1) | JP6731216B2 (ja) |
CN (1) | CN107110768B (ja) |
WO (1) | WO2016063950A1 (ja) |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3643650A (en) * | 1970-05-25 | 1972-02-22 | Harvey A Elder | Method and apparatus for obtaining bacteriological information |
CN1037549C (zh) * | 1992-06-27 | 1998-02-25 | 模数分析体系有限公司 | 自动化验机用的透明小容器 |
US5292000A (en) * | 1992-11-13 | 1994-03-08 | Abner Levy | Holder for medical specimen slide |
US5658413A (en) * | 1994-10-19 | 1997-08-19 | Hewlett-Packard Company | Miniaturized planar columns in novel support media for liquid phase analysis |
US5500071A (en) * | 1994-10-19 | 1996-03-19 | Hewlett-Packard Company | Miniaturized planar columns in novel support media for liquid phase analysis |
JP3427105B2 (ja) * | 1999-08-26 | 2003-07-14 | 株式会社ニコン | 生体試料培養容器 |
JP2005134339A (ja) * | 2003-10-31 | 2005-05-26 | Kuraray Co Ltd | 生物化学用途において蛍光分析に使用される樹脂製プレート、及びその製造方法 |
JP2007240245A (ja) * | 2006-03-07 | 2007-09-20 | Nippon Zeon Co Ltd | 生体分子検査素子用基材及び生体分子検査素子 |
CN201094103Y (zh) * | 2007-07-03 | 2008-07-30 | 广州市第一人民医院 | 用于人体肿瘤检测多波段激发光源发生器 |
US7977660B2 (en) * | 2007-08-14 | 2011-07-12 | General Electric Company | Article, device, and method |
ATE555711T1 (de) * | 2007-12-19 | 2012-05-15 | Kantonsspital Aarau Ag | Verfahren zur analyse und bearbeitung von fluoreszenzbildern |
JP2010249520A (ja) * | 2009-04-10 | 2010-11-04 | Olympus Corp | 液体試料解析用容器及び液体試料の解析方法。 |
DE102009020663A1 (de) * | 2009-05-11 | 2010-11-25 | Carl Zeiss Ag | Mikroskopie eines Objektes mit einer Abfolge von optischer Mikroskopie und Teilchenstrahlmikroskopie |
JP2011220947A (ja) * | 2010-04-14 | 2011-11-04 | Hitachi Engineering & Services Co Ltd | 微生物検査装置及び微生物検査チップ |
CN202305391U (zh) * | 2011-11-04 | 2012-07-04 | 武汉理工大学 | 用于油液红外光谱分析的样品池装置 |
-
2014
- 2014-10-24 JP JP2014217689A patent/JP6731216B2/ja active Active
-
2015
- 2015-10-22 WO PCT/JP2015/079831 patent/WO2016063950A1/ja active Application Filing
- 2015-10-22 CN CN201580057473.8A patent/CN107110768B/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2016085108A (ja) | 2016-05-19 |
WO2016063950A1 (ja) | 2016-04-28 |
CN107110768B (zh) | 2021-08-27 |
CN107110768A (zh) | 2017-08-29 |
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