JP6692795B2 - 眼疾患および眼障害の治療のための方法および組成物 - Google Patents
眼疾患および眼障害の治療のための方法および組成物 Download PDFInfo
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Description
本発明は、眼疾患の分野に関する。具体的には、本発明は、眼疾患、特に異常な血管新生を特徴とする眼疾患の治療のための新規の組成物および方法を提供する。
この出願の発明に関連する先行技術文献情報としては、以下のものがある(国際出願日以降国際段階で引用された文献及び他国に国内移行した際に引用された文献を含む)。
(先行技術文献)
(特許文献)
(特許文献1) 国際公開第2013/023059号
(特許文献2) 米国特許出願公開第2007/0083334号明細書
(特許文献3) 米国特許出願公開第2008/0269120号明細書
(特許文献4) 米国特許出願公開第2006/0275211号明細書
以下の定義は、本発明の理解を助けるために提供される:
単数形「a」、「an」、および「the」は、文脈が明らかにそうでないと指定しない限り複数形の参照対象を含む。
Claims (10)
- 少なくとも1つの抗RhoB抗体またはその抗原結合断片を有する眼疾患の治療のために使用される組成物であって、前記眼疾患は異常な血管新生を特徴とし、
前記抗RhoB抗体またはその抗原結合断片は、配列ID番号:1で示されるアミノ酸配列に免疫学的に特異的に結合するものである、組成物。 - 請求項1記載の組成物であって、さらに、少なくとも1つの薬学的に許容される担体を有する組成物。
- 請求項1記載の組成物において、前記抗RhoB抗体は7F7である組成物。
- 請求項1記載の組成物において、前記眼疾患は網膜症または黄斑変性症である組成物。
- 請求項4記載の組成物において、前記網膜症は未熟網膜症または糖尿病性網膜症である組成物。
- 請求項4記載の組成物において、前記黄斑変性症はウェット型黄斑変性症である組成物。
- 請求項1記載の組成物において、前記組成物はレーザー療法または凍結療法と併用されるためのものである組成物。
- 請求項1記載の組成物であって、さらに、少なくとも1つの血管新生阻害剤を有する組成物。
- 請求項8記載の組成物において、前記血管新生阻害剤は血管内皮増殖因子阻害剤である組成物。
- 請求項9記載の組成物において、前記血管内皮増殖因子阻害剤はラニズマブ、ベバシズマブ、ペガプタニブ、およびアフィルベルセプトからなる群から選択される組成物。
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US201461978061P | 2014-04-10 | 2014-04-10 | |
US61/978,061 | 2014-04-10 | ||
PCT/US2015/025322 WO2015157644A1 (en) | 2014-04-10 | 2015-04-10 | Methods and compositions for the treatment of ocular diseases and disorders |
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JP2017513939A JP2017513939A (ja) | 2017-06-01 |
JP2017513939A5 JP2017513939A5 (ja) | 2018-05-10 |
JP6692795B2 true JP6692795B2 (ja) | 2020-05-13 |
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US (1) | US11447568B2 (ja) |
EP (1) | EP3129054B1 (ja) |
JP (1) | JP6692795B2 (ja) |
AU (1) | AU2015243261B2 (ja) |
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US7795218B2 (en) * | 2001-04-12 | 2010-09-14 | Bioaxone Therapeutique Inc. | ADP-ribosyl transferase fusion variant proteins |
US20040142325A1 (en) | 2001-09-14 | 2004-07-22 | Liat Mintz | Methods and systems for annotating biomolecular sequences |
WO2003040340A2 (en) | 2001-11-07 | 2003-05-15 | Agensys, Inc. | Nucleic acid and corresponding protein entitled 161p2f10b useful in treatment and detection of cancer |
US8470784B2 (en) | 2009-08-24 | 2013-06-25 | Stealth Peptides International, Inc. | Methods and compositions for preventing or treating ophthalmic conditions |
US8759298B2 (en) | 2010-05-03 | 2014-06-24 | Scott & White Healthcare | Protein therapy for corneal inflammation, epithelial wound healing, and photoreceptor degeneration |
SG195100A1 (en) * | 2011-07-01 | 2013-12-30 | Bayer Ip Gmbh | Hydroxymethylaryl-substituted pyrrolotriazines as alk1 inhibitors |
US20130123330A1 (en) | 2011-07-15 | 2013-05-16 | Patrick Y. Lu | Dual Targeted siRNA Therapeutics for Treatment of Diabetic Retinopathy and Other Ocular Neovascularization Diseases |
ES2813415T3 (es) | 2011-08-10 | 2021-03-23 | Lankenau Inst Medical Res | Métodos y composiciones para el tratamiento de enfermedades autoinmunes e inflamatorias |
TW201406707A (zh) | 2012-05-04 | 2014-02-16 | Acucela Inc | 用以治療糖尿病性視網膜病變及其他眼部疾病之方法 |
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US11447568B2 (en) | 2022-09-20 |
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JP2017513939A (ja) | 2017-06-01 |
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