JP6691869B2 - ファシンを阻害するための化合物及び方法 - Google Patents

ファシンを阻害するための化合物及び方法 Download PDF

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JP6691869B2
JP6691869B2 JP2016552984A JP2016552984A JP6691869B2 JP 6691869 B2 JP6691869 B2 JP 6691869B2 JP 2016552984 A JP2016552984 A JP 2016552984A JP 2016552984 A JP2016552984 A JP 2016552984A JP 6691869 B2 JP6691869 B2 JP 6691869B2
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cancer
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JP2017506248A5 (enExample
JP2017506248A (ja
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シン−ユン フアン
シン−ユン フアン
クリスティー ヤング シュー
クリスティー ヤング シュー
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コーネル ユニヴァーシティー
コーネル ユニヴァーシティー
ノヴィタ ファーマシューティカルズ インコーポレイテッド
ノヴィタ ファーマシューティカルズ インコーポレイテッド
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C07D209/04—Indoles; Hydrogenated indoles
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    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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  • Organic Chemistry (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Engineering & Computer Science (AREA)
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  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
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  • Hospice & Palliative Care (AREA)
  • Virology (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
JP2016552984A 2014-02-20 2015-02-19 ファシンを阻害するための化合物及び方法 Active JP6691869B2 (ja)

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US201461942554P 2014-02-20 2014-02-20
US61/942,554 2014-02-20
PCT/US2015/016686 WO2015127125A1 (en) 2014-02-20 2015-02-19 Compounds and methods for inhibiting fascin

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JP2017506248A JP2017506248A (ja) 2017-03-02
JP2017506248A5 JP2017506248A5 (enExample) 2018-03-29
JP6691869B2 true JP6691869B2 (ja) 2020-05-13

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US (7) US9573946B2 (enExample)
EP (1) EP3107902B1 (enExample)
JP (1) JP6691869B2 (enExample)
CN (2) CN106232583B (enExample)
CA (2) CA3195815A1 (enExample)
DK (1) DK3107902T3 (enExample)
ES (1) ES2868882T3 (enExample)
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