JP6678101B2 - 疎水性組織接着剤 - Google Patents

疎水性組織接着剤 Download PDF

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Publication number
JP6678101B2
JP6678101B2 JP2016515127A JP2016515127A JP6678101B2 JP 6678101 B2 JP6678101 B2 JP 6678101B2 JP 2016515127 A JP2016515127 A JP 2016515127A JP 2016515127 A JP2016515127 A JP 2016515127A JP 6678101 B2 JP6678101 B2 JP 6678101B2
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JP
Japan
Prior art keywords
prepolymer
tissue
patch
hlaa
groups
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
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JP2016515127A
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English (en)
Japanese (ja)
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JP2016526078A (ja
JP2016526078A5 (enExample
Inventor
ジェフリー エム. カープ,
ジェフリー エム. カープ,
ニード, ペドロ デル
ニード, ペドロ デル
ノラ ラング,
ノラ ラング,
ランガー, ロバート エス.
ロバート エス. ランガー,
マリア ホセ エミ.エニ. ペレイラ,
マリア ホセ エミ.エニ. ペレイラ,
ユハン リー,
ユハン リー,
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brigham and Womens Hospital Inc
Original Assignee
Brigham and Womens Hospital Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham and Womens Hospital Inc filed Critical Brigham and Womens Hospital Inc
Publication of JP2016526078A publication Critical patent/JP2016526078A/ja
Publication of JP2016526078A5 publication Critical patent/JP2016526078A5/ja
Application granted granted Critical
Publication of JP6678101B2 publication Critical patent/JP6678101B2/ja
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Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/046Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/26Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/58Adhesives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001Use of materials characterised by their function or physical properties
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/12Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from polycarboxylic acids and polyhydroxy compounds
    • C08G63/46Polyesters chemically modified by esterification
    • C08G63/47Polyesters chemically modified by esterification by unsaturated monocarboxylic acids or unsaturated monohydric alcohols or reactive derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/91Polymers modified by chemical after-treatment
    • C08G63/914Polymers modified by chemical after-treatment derived from polycarboxylic acids and polyhydroxy compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/18Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/10Esters
    • C08F222/1006Esters of polyhydric alcohols or polyhydric phenols
    • C08F222/106Esters of polycondensation macromers
    • C08F222/1061Esters of polycondensation macromers of alcohol terminated polyesters or polycarbonates, e.g. polyester (meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials For Medical Uses (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Adhesives Or Adhesive Processes (AREA)
JP2016515127A 2013-05-24 2014-05-23 疎水性組織接着剤 Active JP6678101B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361827240P 2013-05-24 2013-05-24
US61/827,240 2013-05-24
US201461924864P 2014-01-08 2014-01-08
US61/924,864 2014-01-08
PCT/US2014/039417 WO2014190302A1 (en) 2013-05-24 2014-05-23 Hydrophobic tissue adhesives

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019019676A Division JP2019081906A (ja) 2013-05-24 2019-02-06 疎水性組織接着剤

Publications (3)

Publication Number Publication Date
JP2016526078A JP2016526078A (ja) 2016-09-01
JP2016526078A5 JP2016526078A5 (enExample) 2017-06-22
JP6678101B2 true JP6678101B2 (ja) 2020-04-08

Family

ID=50983193

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2016515127A Active JP6678101B2 (ja) 2013-05-24 2014-05-23 疎水性組織接着剤
JP2019019676A Pending JP2019081906A (ja) 2013-05-24 2019-02-06 疎水性組織接着剤

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2019019676A Pending JP2019081906A (ja) 2013-05-24 2019-02-06 疎水性組織接着剤

Country Status (8)

Country Link
US (1) US9724447B2 (enExample)
EP (2) EP3950018B1 (enExample)
JP (2) JP6678101B2 (enExample)
CN (2) CN105377963B (enExample)
BR (1) BR112015029078B1 (enExample)
CA (1) CA2913338C (enExample)
ES (1) ES2899023T3 (enExample)
WO (1) WO2014190302A1 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12465491B2 (en) * 2010-07-27 2025-11-11 Tenon Medical, Inc. Methods for sacroiliac joint stabilization
US12472069B2 (en) * 2010-07-27 2025-11-18 Tenon Medical, Inc. Methods for sacroiliac joint stabilization
US12409039B2 (en) * 2010-07-27 2025-09-09 Tenon Medical, Inc. Systems for sacroiliac joint stabilization
EP3950018B1 (en) * 2013-05-24 2025-10-15 Massachusetts Institute Of Technology Hydrophobic tissue adhesives
WO2016124202A1 (en) 2015-02-02 2016-08-11 Coloplast A/S Ostomy device
BR112017021501A2 (pt) 2015-04-10 2018-07-03 Coloplast As ?dispositivo de ostomia, e, método para aplicação de um dispositivo de ostomia?
US11898005B2 (en) * 2015-06-18 2024-02-13 Tissium Sa Sealant composition
KR20180019670A (ko) * 2015-06-18 2018-02-26 게코 바이오메디칼 접착제 조성물
ES3015254T3 (en) 2015-06-18 2025-04-30 Tissium Sa Sealant composition
CN106769502A (zh) * 2016-12-02 2017-05-31 杭州亚慧生物科技有限公司 一种外科手术封合剂胀破强度检测装置
CN107063873A (zh) * 2016-12-02 2017-08-18 杭州亚慧生物科技有限公司 一种外科手术封合剂恒温胀破强度检测装置
EP3600159B1 (en) 2017-03-22 2022-04-06 Edwards Lifesciences Corporation System for implanting and securing a bioprosthetic device to wet tissue
CN110996805B (zh) 2017-05-25 2024-03-19 泰尔茂株式会社 粘合封堵系统
EP3409239A1 (en) 2017-05-29 2018-12-05 University College Dublin, National University of Ireland, Dublin An implantable active agent encapsulating device
EP3697318B1 (en) * 2017-10-20 2024-08-14 Edwards Lifesciences Corporation Localized fusion of native leaflets using activated adhesive
EP3560427A1 (en) 2018-04-24 2019-10-30 Gecko Biomedical Applicator for depositing a layer of adhesive or sealant composition on a biological and/or prosthetic tissue
AU2019299519B2 (en) 2018-07-02 2025-03-06 Incept Llc Methods and devices for in situ formed nerve cap
JP2021006140A (ja) * 2019-06-28 2021-01-21 三洋化成工業株式会社 医療用接着剤
JP7260655B2 (ja) * 2019-09-27 2023-04-18 富士フイルム株式会社 ポリマー、硬化性組成物、硬化物
BR112022007788A2 (pt) 2019-10-25 2022-07-05 Tissium Sa Composição compreendendo pré-polímero ativado e funcionalizado
EP4076282A1 (en) 2019-12-20 2022-10-26 Edwards Lifesciences Innovation (Israel) Ltd. Implant-adhering techniques
CN116867525A (zh) * 2021-01-18 2023-10-10 缇斯股份有限公司 外科材料
CA3209123A1 (en) 2021-02-24 2022-09-01 Camille Legros Composition comprising activated and functionalized pre-polymer
CN115501381B (zh) * 2022-09-23 2023-10-03 北京大学 替代可吸收缝合线的脂肪组织粘合剂、制备方法及其应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
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DE13023C (de) J. JAEGLE in Mülhausen i. E. Regulator für selbstwirkende Feinspinnmaschinen. !
JPH0681782B2 (ja) * 1985-07-19 1994-10-19 東亞合成化学工業株式会社 ポリエステルポリ(メタ)アクリレートの製造法
JP3560096B2 (ja) * 1996-02-02 2004-09-02 日本ゼオン株式会社 重合性不飽和化合物及びそれを含む硬化性樹脂組成物並びに成形体
CN1225014A (zh) * 1996-07-11 1999-08-04 生命医学科学公司 减少或消除术后粘着形成的方法和组合物
AU2022599A (en) * 1997-12-31 1999-07-19 Kimberly-Clark Worldwide, Inc. Method of reducing molecular weights and polydispersity indices of polymers of ethylene oxide
WO2003104300A1 (de) * 2002-06-01 2003-12-18 Basf Aktiengesellschaft (meth)acrylester von polyalkoxyliertem trimethylolpropan
US20040120981A1 (en) * 2002-12-20 2004-06-24 Aruna Nathan Crosslinked alkyd polyesters for medical applications
KR20060122919A (ko) * 2004-01-14 2006-11-30 사이텍 설패이스 스페셜티즈, 에스.에이. 접착제
DE102004049544A1 (de) * 2004-10-12 2006-04-13 Degussa Ag Strahlungshärtbar modifizierte, ungesättigte, amorphe Polyester
JP5175041B2 (ja) * 2005-09-21 2013-04-03 コスメディ製薬株式会社 親水性粘着剤、それを用いた親水性皮膚外用粘着剤組成物および親水性貼付剤
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EP3950018B1 (en) * 2013-05-24 2025-10-15 Massachusetts Institute Of Technology Hydrophobic tissue adhesives

Also Published As

Publication number Publication date
JP2019081906A (ja) 2019-05-30
HK1221238A1 (zh) 2017-05-26
EP3950018A1 (en) 2022-02-09
CN105377963A (zh) 2016-03-02
BR112015029078A8 (pt) 2020-03-17
BR112015029078B1 (pt) 2020-12-08
US20140348896A1 (en) 2014-11-27
CN105377963B (zh) 2018-11-27
ES2899023T3 (es) 2022-03-09
CA2913338C (en) 2018-05-01
WO2014190302A1 (en) 2014-11-27
EP3950018B1 (en) 2025-10-15
JP2016526078A (ja) 2016-09-01
EP3004221B1 (en) 2021-10-27
EP3004221A1 (en) 2016-04-13
CN110051876A (zh) 2019-07-26
US9724447B2 (en) 2017-08-08
BR112015029078A2 (pt) 2017-08-22
CN110051876B (zh) 2022-05-31
CA2913338A1 (en) 2014-11-27

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