JP6568052B2 - 心不全を治療するためのニューレグリンの徐放 - Google Patents

心不全を治療するためのニューレグリンの徐放 Download PDF

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JP6568052B2
JP6568052B2 JP2016514266A JP2016514266A JP6568052B2 JP 6568052 B2 JP6568052 B2 JP 6568052B2 JP 2016514266 A JP2016514266 A JP 2016514266A JP 2016514266 A JP2016514266 A JP 2016514266A JP 6568052 B2 JP6568052 B2 JP 6568052B2
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neuregulin
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pharmaceutical composition
pump
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JP2016520089A (ja
JP2016520089A5 (enExample
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ズホウ ミングドング
ズホウ ミングドング
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ゼンサン （シャンハイ） サイエンス アンド テクノロジー，シーオー．，エルティーディー．
ゼンサン （シャンハイ） サイエンス アンド テクノロジー，シーオー．，エルティーディー．
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1883—Neuregulins, e.g.. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hospice & Palliative Care (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Medical Informatics (AREA)
  • Medicinal Preparation (AREA)
JP2016514266A 2013-05-22 2014-05-22 心不全を治療するためのニューレグリンの徐放 Active JP6568052B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361826433P 2013-05-22 2013-05-22
US61/826,433 2013-05-22
PCT/CN2014/078154 WO2014187342A1 (en) 2013-05-22 2014-05-22 Extended Release of Neuregulin for Treating Heart Failure

Related Child Applications (1)

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JP2019108985A Division JP2019172689A (ja) 2013-05-22 2019-06-11 心不全を治療するためのニューレグリンの徐放

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JP2016520089A JP2016520089A (ja) 2016-07-11
JP2016520089A5 JP2016520089A5 (enExample) 2017-06-29
JP6568052B2 true JP6568052B2 (ja) 2019-09-04

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JP2016514266A Active JP6568052B2 (ja) 2013-05-22 2014-05-22 心不全を治療するためのニューレグリンの徐放
JP2019108985A Pending JP2019172689A (ja) 2013-05-22 2019-06-11 心不全を治療するためのニューレグリンの徐放

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US (4) US10098834B2 (enExample)
EP (3) EP2999499B1 (enExample)
JP (2) JP6568052B2 (enExample)
KR (3) KR20230132635A (enExample)
CN (2) CN105611955A (enExample)
AU (2) AU2014270882B2 (enExample)
BR (1) BR112015029293A2 (enExample)
CA (1) CA2911848A1 (enExample)
ES (1) ES2743617T3 (enExample)
RU (1) RU2015154737A (enExample)
WO (1) WO2014187342A1 (enExample)

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CA2841386A1 (en) 2005-12-30 2007-07-12 Zensun (Shanghai) Science & Technology Limited Extended release of neuregulin for improved cardiac function
JP6096262B2 (ja) 2009-08-25 2017-03-15 ゼンサン （シャンハイ） サイエンス アンド テクノロジー，シーオー．，エルティーディー． ニューレグリンに基づく心不全の治療方法
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WO2013053076A1 (en) 2011-10-10 2013-04-18 Zensun （Shanghai）Science & Technology Limited Compositions and methods for treating heart failure
RU2650635C2 (ru) 2012-10-08 2018-04-16 Цзэньсунь (Шанхай) Сайенс Энд Текнолоджи, Ко., Лтд. Композиции и способы лечения сердечной недостаточности у пациентов с диабетом
CA2911848A1 (en) 2013-05-22 2014-11-27 Zensun (Shanghai) Science & Technology, Ltd. Extended release of neuregulin for treating heart failure
CN110946993A (zh) 2014-01-03 2020-04-03 上海泽生科技开发股份有限公司 纽兰格林制剂的配方
CN105497876B (zh) 2014-09-24 2021-01-15 上海泽生科技开发股份有限公司 神经调节蛋白用于预防、治疗或延迟心脏室性心律失常的方法和组合物
CN111407882A (zh) 2014-10-17 2020-07-14 上海泽生科技开发股份有限公司 神经调节蛋白用于预防、治疗或延迟射血分数保留的心力衰竭的方法和组合物
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CN111407882A (zh) 2014-10-17 2020-07-14 上海泽生科技开发股份有限公司 神经调节蛋白用于预防、治疗或延迟射血分数保留的心力衰竭的方法和组合物
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US20160089329A1 (en) 2016-03-31
CA2911848A1 (en) 2014-11-27
CN112168953A (zh) 2021-01-05
EP3895724A1 (en) 2021-10-20
RU2015154737A (ru) 2017-06-27
ES2743617T3 (es) 2020-02-20
JP2016520089A (ja) 2016-07-11
EP2999499B1 (en) 2019-07-17
RU2015154737A3 (enExample) 2018-04-26
AU2014270882A1 (en) 2015-11-26
AU2019203799B2 (en) 2021-05-20
KR20160009575A (ko) 2016-01-26
US20190240145A1 (en) 2019-08-08
AU2014270882B2 (en) 2019-03-14
KR20220018076A (ko) 2022-02-14
KR102357275B1 (ko) 2022-02-03
EP3610905B1 (en) 2021-03-31
KR102578135B1 (ko) 2023-09-13
EP2999499A4 (en) 2017-01-18
US12208158B2 (en) 2025-01-28
EP2999499A1 (en) 2016-03-30
US20250360078A1 (en) 2025-11-27
WO2014187342A1 (en) 2014-11-27
JP2019172689A (ja) 2019-10-10
EP3895724B1 (en) 2025-06-25
KR20230132635A (ko) 2023-09-15
EP3610905A1 (en) 2020-02-19
US20220211613A1 (en) 2022-07-07
US10098834B2 (en) 2018-10-16
BR112015029293A2 (pt) 2018-04-24
US11179323B2 (en) 2021-11-23
CN105611955A (zh) 2016-05-25
AU2019203799A1 (en) 2019-06-20

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