JP6535022B2 - ヘテロアリールｓｙｋ阻害剤 - Google Patents

ヘテロアリールｓｙｋ阻害剤 Download PDF

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JP6535022B2
JP6535022B2 JP2016557602A JP2016557602A JP6535022B2 JP 6535022 B2 JP6535022 B2 JP 6535022B2 JP 2016557602 A JP2016557602 A JP 2016557602A JP 2016557602 A JP2016557602 A JP 2016557602A JP 6535022 B2 JP6535022 B2 JP 6535022B2
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amino
acid
methyl
phenyl
ethyl
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JP2017512779A (ja
JP2017512779A5 (enExample
Inventor
ダーマン，ゲオルク
ホフマン，マティアス
クリシク，ヤスナ
ラム，デイビッド・ジェームズ
マッカーシー，クライブ
ネイピア，スペンサー
パリッシュ，カレン
スコット，ジョン
フィッツジェラルド，ジェニファー・エル・スワンテック
ウォーカー，エドワード
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ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4162—1,2-Diazoles condensed with heterocyclic ring systems
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    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
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