JP6514211B2 - 薬物を連続して送達するためのアセンブリ及び関連方法 - Google Patents

薬物を連続して送達するためのアセンブリ及び関連方法 Download PDF

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Publication number
JP6514211B2
JP6514211B2 JP2016541980A JP2016541980A JP6514211B2 JP 6514211 B2 JP6514211 B2 JP 6514211B2 JP 2016541980 A JP2016541980 A JP 2016541980A JP 2016541980 A JP2016541980 A JP 2016541980A JP 6514211 B2 JP6514211 B2 JP 6514211B2
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Prior art keywords
nozzle
drug
plunger
infusion
stopper piston
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Japanese (ja)
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JP2016533848A5 (enExample
JP2016533848A (ja
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ブラッドリー，クリストファー・マイケル
ワイアット，ローランド・ジェフリー
ティリー，ジェフリー・アラン
コールスタッド，ブラッドリー・ウェルディング
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ゾエティス・サービシーズ・エルエルシー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/19—Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M5/31513—Piston constructions to improve sealing or sliding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • A61M5/422—Desensitising skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M2005/1787—Syringes for sequential delivery of fluids, e.g. first medicament and then flushing liquid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • A61M2005/31598—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing having multiple telescopically sliding coaxial pistons encompassing volumes for components to be mixed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M5/31515—Connection of piston with piston rod

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2016541980A 2013-09-16 2014-08-15 薬物を連続して送達するためのアセンブリ及び関連方法 Active JP6514211B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361878162P 2013-09-16 2013-09-16
US61/878,162 2013-09-16
US201462026936P 2014-07-21 2014-07-21
US62/026,936 2014-07-21
PCT/US2014/051194 WO2015038281A1 (en) 2013-09-16 2014-08-15 Assembly for sequentially delivering substances, and associated methods

Publications (3)

Publication Number Publication Date
JP2016533848A JP2016533848A (ja) 2016-11-04
JP2016533848A5 JP2016533848A5 (enExample) 2019-02-28
JP6514211B2 true JP6514211B2 (ja) 2019-05-15

Family

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JP2016541980A Active JP6514211B2 (ja) 2013-09-16 2014-08-15 薬物を連続して送達するためのアセンブリ及び関連方法

Country Status (10)

Country Link
US (1) US9694134B2 (enExample)
EP (1) EP3046605B1 (enExample)
JP (1) JP6514211B2 (enExample)
CN (1) CN105530975B (enExample)
AU (1) AU2014318264B2 (enExample)
BR (1) BR112016005795B1 (enExample)
CA (1) CA2923555C (enExample)
MX (1) MX373718B (enExample)
NZ (1) NZ718062A (enExample)
WO (1) WO2015038281A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3077942C (en) 2015-05-06 2022-05-10 Zoetis Services Llc Hydrogel formulation with mild adhesion
KR102145435B1 (ko) 2015-11-03 2020-08-18 조에티스 서비시즈 엘엘씨 졸-겔 폴리머 복합체 및 이의 용도
EP3374002A1 (en) 2015-11-13 2018-09-19 Bayer Healthcare LLC Nested syringe assembly
US20170153165A1 (en) * 2015-11-30 2017-06-01 Chidozie O. Nwadigo Syringe assembly for withdrawing two separate portions of fluid following a single engagement with fluid port
US11167085B2 (en) 2016-06-15 2021-11-09 True Concepts Medical Technologies, Llc Syringe systems and methods for multi-stage fluid delivery
US10022079B2 (en) 2016-06-15 2018-07-17 True Concepts Medical Technologies, Llc Syringe systems and methods for bodily fluid collection and sampling
WO2018062496A1 (ja) * 2016-09-30 2018-04-05 テルモ株式会社 プレフィルドシリンジ及びシリンジ
KR101879211B1 (ko) * 2017-02-14 2018-07-17 진세훈 진피 재생용 주사기
CA3057856A1 (en) 2017-04-20 2018-10-25 Zoetis Services Llc Veterinary compositions for use in treating mastitis, and associated methods
CN107158526B (zh) * 2017-05-27 2020-05-01 王阔 一种低分子量肝素注射护理操作标尺盘
WO2019108747A1 (en) 2017-12-01 2019-06-06 Zoetis Services Llc Hydrogel compositions and uses thereof
US11229722B2 (en) * 2018-01-29 2022-01-25 Omer Peled System and method for harvesting autologous adipose tissue
JP7177166B2 (ja) * 2018-03-20 2022-11-22 ベクトン・ディキンソン・アンド・カンパニー 注射器アセンブリ用の注射器ストッパおよびプランジャロッドの配置
CA3129652A1 (en) * 2019-02-27 2020-09-03 Becton Dickinson France Valve stopper for a medical injection device and medical injection device for injecting at least one composition
RU2721823C1 (ru) * 2019-06-04 2020-05-22 Александр Ильич Абовян Карпульный инъектор
BR112022015321A2 (pt) 2020-02-03 2022-09-20 Curemast Inc Composição e método para tratamento de mastite e método de tratamento de mastite em uma vaca ou cabra leiteira
CN111207959B (zh) * 2020-03-04 2022-08-26 常州工业及消费品检验有限公司 一种氧化性液体进样器
KR20220034430A (ko) * 2020-09-11 2022-03-18 진세훈 주사기 작동 장치

Family Cites Families (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2159217A (en) 1937-11-05 1939-05-23 Cook Lab Inc Controllable transfer element for multiple ampules
US2193322A (en) 1938-04-30 1940-03-12 Cook Lab Inc Controllable transfer element for multiple compartment ampules
US2687728A (en) 1951-04-25 1954-08-31 Copen Simon Irving Combination of several solutions for the hypodermic injection
US2939459A (en) 1957-01-11 1960-06-07 Jorge A Lazarte Tandem syringe
US3563240A (en) 1966-07-20 1971-02-16 Jules Silver Dual unit syringe
US3346147A (en) 1966-08-18 1967-10-10 Brunswick Corp Dental compound syringe
US3766917A (en) 1968-01-26 1973-10-23 West Co Two compartment ampul syringe
US3570486A (en) * 1968-10-14 1971-03-16 Horizon Ind Ltd Mixing syringe
FR2076853A5 (en) 1970-01-30 1971-10-15 Rhone Poulenc Sa Ampoule with bosses - and syringe for use with ampoules
US3749084A (en) 1971-05-03 1973-07-31 A Cucchiara Sequentially dispensing syringe with multiple needle assembly
US3911916A (en) 1971-10-29 1975-10-14 Peter A Stevens Sequential injection syringe
US3923058A (en) 1972-05-19 1975-12-02 Kendall & Co Multi-chamber syringe
GB1441747A (en) 1972-10-18 1976-07-07 Lazonby B Veterinary compositions
US3835835A (en) * 1972-11-07 1974-09-17 Richardson Merrell Inc Two compartment locking sampling syringe
US3986645A (en) 1972-12-01 1976-10-19 Mpl, Inc. Liquid dispenser
FR2251339A1 (en) 1973-11-19 1975-06-13 Bouvier Christian Two-compartment syringe for parenteral injections - for successive injections of two liquids
DE2514201A1 (de) 1975-04-01 1976-10-14 Werner Ide Injektionsspritze, insbesondere fuer intraarterielle injektionen
US4188949A (en) 1977-07-05 1980-02-19 Becton, Dickinson & Company Sequential injection syringe
US4313440A (en) * 1980-09-08 1982-02-02 Ashley Sheldon J Multipurpose double barrel syringe and method of manufacture of same
FR2506161A1 (fr) 1981-05-20 1982-11-26 Alsetex Armement Seringue auto-injectante
US4394863A (en) 1981-10-23 1983-07-26 Survival Technology, Inc. Automatic injector with cartridge having separate sequentially injectable medicaments
DE3270641D1 (en) 1981-11-11 1986-05-22 Contraves Ag Syringe for a sequential injection of two fluids into blood vessels of living bodies
EP0082251B1 (de) 1981-12-22 1987-08-05 Contraves Ag Injektionsspritze für zwei Flüssigkeiten
JPS58133260A (ja) 1982-02-02 1983-08-08 河村　純郎 多段注射器
US4439184A (en) 1982-05-03 1984-03-27 Concord Laboratories, Inc. Two-dose syringe
FR2573310B1 (fr) 1984-11-20 1988-12-30 Poutrait Morin Ampoule pour seringue hypodermique, en particulier seringue auto-injectante
US4702737A (en) 1986-07-14 1987-10-27 Pizzino Joanne L Dual dose syringe
AU1916088A (en) 1987-07-21 1989-01-27 Dowty Seals Limited Non-reusable syringe
NO884377L (no) * 1988-10-03 1990-04-04 Ken Heimreid Doserings-/blandesproeyte.
US5092843A (en) 1990-04-12 1992-03-03 Survival Technology, Inc. Dispersion multichamber auto-injector
US5102388A (en) 1991-07-15 1992-04-07 Richmond John E Sequential delivery syringe
US5279606A (en) 1991-08-28 1994-01-18 Habley Medical Technology Corporation Non-reactive composite sealing barrier
CA2150255C (en) 1992-12-01 1999-08-03 Tetsuro Higashikawa Syringe
EP0673239B1 (en) 1992-12-08 1998-06-10 Bimeda Research And Development Limited Aqueous antibiotic composition for veterinary use
WO1995031180A1 (en) 1992-12-08 1995-11-23 Bimeda Research And Development Limited A veterinary composition
US5298024A (en) 1992-12-28 1994-03-29 Frank Richmond Multi-liquid medicament delivery system with reflex valves
US5476449A (en) 1992-12-28 1995-12-19 Richmond; Frank M. Needleless multi-liquid medicament delivery system with membranes
US5415648A (en) 1993-07-08 1995-05-16 Malay; Manuel R. Multiple purpose syringe
US5520657A (en) 1993-08-09 1996-05-28 Sellers; Jackie Method and device for vessel location cannulation utilizing a unique needle and syringe device
US5876372A (en) * 1995-03-22 1999-03-02 Abbott Laboratories Syringe system accomodating seperate prefilled barrels for two constituents
JPH08280800A (ja) 1995-04-12 1996-10-29 Nissho Corp ２液注射用プレフィルドシリンジ
JP3419145B2 (ja) 1995-04-25 2003-06-23 ニプロ株式会社 プレフィルドシリンジ
FR2750051A1 (fr) 1996-06-21 1997-12-26 Debiotech Sa Seringue medicale a piston libre
NZ336153A (en) 1996-12-18 2000-06-23 Bimeda Res & Dev Ltd Antiinfective free intramammary veterinary composition comprising a gel and a heavy metal compound for the prevention of mastitis
US6077252A (en) 1997-09-17 2000-06-20 Siegel; Robert Single or multiple dose syringe
WO1999017820A1 (en) 1997-10-03 1999-04-15 Texas Pharmaceuticals, Inc. Improved dual chamber syringe apparatus
US6458095B1 (en) 1997-10-22 2002-10-01 3M Innovative Properties Company Dispenser for an adhesive tissue sealant having a housing with multiple cavities
US6149628A (en) 1998-07-20 2000-11-21 Szapiro; Jaime Luis Syringe with two variable volume chambers for containing and administering mixtures of products provided separately
US6270482B1 (en) 1999-09-09 2001-08-07 Tri-Med International, Llc Multiple-dose syringe
US7011650B2 (en) 1999-09-09 2006-03-14 Paradigm Medical, Llc Multiple-dose syringe with collapsible container
US6802822B1 (en) 2000-03-31 2004-10-12 3M Innovative Properties Company Dispenser for an adhesive tissue sealant having a flexible link
US6440101B1 (en) 2000-05-31 2002-08-27 Abbott Laboratories Syringe systems for lyophilized drugs and methods for making the same
WO2002011793A1 (fr) 2000-08-08 2002-02-14 Medical Information Services, Inc. Seringue pour preparation de necessaire d'injection, valve coulissante intermediaire pour seringues et preparation de necessaire d'injection
AR026723A1 (es) 2000-12-05 2003-02-26 Szames Leonardo Conjunto valvular elastico y deslizante apto para actuar en el interior de jeringas prellenadas.
DE10110126A1 (de) 2001-03-02 2002-09-19 Dieter Gassen Zweikammerspritze für Spritzenpumpen
CN1509195A (zh) 2001-03-13 2004-06-30 MDCͶ�ʿعɹ�˾ 预充填的安全稀释剂注射器
FR2822710B1 (fr) 2001-03-27 2004-04-02 Lab Contactologie Appl Lca Seringue pour solutions viscoleastiques
GB2376048B (en) 2001-03-31 2004-11-10 David William Armfield Pistons
EP1424995B1 (en) 2001-09-10 2010-07-14 Bimeda Research And Development Limited A bio-security system
JP4112851B2 (ja) 2001-11-27 2008-07-02 テルモ株式会社 ２室型プレフィルドシリンジ
US6723074B1 (en) 2002-04-09 2004-04-20 Thor R. Halseth Sequential delivery syringe
JP2003299734A (ja) 2002-04-12 2003-10-21 Igaku Joho Service:Kk 注射器型キット製剤及びその製造方法
US6945962B2 (en) 2002-06-21 2005-09-20 Jeffrey S. Mortimer Sequential syringe apparatus
US20040044316A1 (en) 2002-08-30 2004-03-04 Greenfield Christian John Syringe for sequential delivery of different fluids
US6866653B2 (en) 2002-10-31 2005-03-15 Kyongtae T. Bae Method and apparatus for sequential delivery of multiple injectable substances stored in a prefilled syringe
MXPA06004418A (es) 2003-10-24 2006-07-06 Mdc Invest Holdings Inc Jeringa de mezclado de camara dual y metodo de uso.
AR054639A1 (es) 2004-02-02 2007-07-11 Bimeda Res & Dev Ltd Un metodo y dispositivo
US6997910B2 (en) 2004-05-03 2006-02-14 Infusive Technologies, Llc Multi-chamber, sequential dose dispensing syringe
CN101312759B (zh) * 2004-12-24 2013-04-10 科林专利控股有限公司 安全注射器
EP1893257A1 (en) 2005-05-16 2008-03-05 Mallinckrodt, Inc. Multi-stage syringe and methods of using the same
WO2006128915A1 (de) * 2005-06-02 2006-12-07 Schwoebel Eckhard Mehrzylinderspritze
WO2007006030A2 (en) 2005-06-30 2007-01-11 Mallinckrodt Inc. Dual chamber syringe
US7959943B2 (en) * 2006-05-10 2011-06-14 Medtronics Xomed, Inc. Solvating system and sealant for medical use in the middle or inner ear
US7879002B2 (en) * 2007-10-31 2011-02-01 Ultradent Products, Inc. Mixing device including a plunging mixing member for use with a syringe
US8353862B2 (en) * 2007-11-02 2013-01-15 Allergan, Inc. Drug delivery systems and methods
US20100286513A1 (en) * 2008-01-23 2010-11-11 Pollard Jr Ralph E Plunger Adapter for Coaxial Syringe System
US8945070B2 (en) 2008-03-14 2015-02-03 Merial Limited Veterinary syringe for multiple injections
US8152778B2 (en) * 2008-09-30 2012-04-10 Tyco Healthcare Group Lp Device for interfacing with standard luer lock syringes
US8162875B2 (en) * 2008-09-30 2012-04-24 Tyco Healthcare Group Ip Diluent/medication mixing syringe assembly
US8992505B2 (en) * 2011-04-18 2015-03-31 Thorne Consulting & Intellectual Property, LLC Medical syringe filling and valving
GB201113606D0 (en) 2011-08-05 2011-09-21 Norbrook Lab Ltd Dual chamber syringe
BE1020614A5 (nl) * 2012-01-27 2014-01-07 Hubert De Backer Nv Injectiespuit.
CN202605441U (zh) 2012-06-29 2012-12-19 李莹 胰岛素药瓶组合式注射器
KR20150030707A (ko) 2012-06-29 2015-03-20 바이엘 애니멀 헬스 게엠베하 약학 조성물 및 유방염 치료
US20140276630A1 (en) 2013-03-15 2014-09-18 Aurora Pharmaceutical, LLC Syringe with retractor

Also Published As

Publication number Publication date
NZ718062A (en) 2017-07-28
CA2923555A1 (en) 2015-03-19
BR112016005795A2 (enExample) 2017-08-01
WO2015038281A1 (en) 2015-03-19
EP3046605B1 (en) 2019-01-09
MX373718B (es) 2020-05-08
CN105530975B (zh) 2019-09-13
AU2014318264A1 (en) 2016-04-07
CN105530975A (zh) 2016-04-27
BR112016005795B1 (pt) 2022-07-12
MX2016003392A (es) 2016-10-28
US9694134B2 (en) 2017-07-04
AU2014318264B2 (en) 2018-10-04
CA2923555C (en) 2020-06-16
EP3046605A1 (en) 2016-07-27
US20150080841A1 (en) 2015-03-19
JP2016533848A (ja) 2016-11-04

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