JP6473292B2 - ワクチン組成物 - Google Patents
ワクチン組成物 Download PDFInfo
- Publication number
- JP6473292B2 JP6473292B2 JP2014014809A JP2014014809A JP6473292B2 JP 6473292 B2 JP6473292 B2 JP 6473292B2 JP 2014014809 A JP2014014809 A JP 2014014809A JP 2014014809 A JP2014014809 A JP 2014014809A JP 6473292 B2 JP6473292 B2 JP 6473292B2
- Authority
- JP
- Japan
- Prior art keywords
- receptor
- receptor agonist
- peptide
- agonist
- receptor antagonist
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- UGYXPZQILZRKJJ-UHFFFAOYSA-N Cc1c(CCN)nc[nH]1 Chemical compound Cc1c(CCN)nc[nH]1 UGYXPZQILZRKJJ-UHFFFAOYSA-N 0.000 description 1
- 0 Cc1ccc(cc(-c(c(CC2)c3)cc4c3OCO4)*2c2)c2c1O Chemical compound Cc1ccc(cc(-c(c(CC2)c3)cc4c3OCO4)*2c2)c2c1O 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K31/426—1,3-Thiazoles
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- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
- A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
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- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
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- A—HUMAN NECESSITIES
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Virology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2014014809A JP6473292B2 (ja) | 2013-02-05 | 2014-01-29 | ワクチン組成物 |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2013020734 | 2013-02-05 | ||
JP2013020734 | 2013-02-05 | ||
JP2014014809A JP6473292B2 (ja) | 2013-02-05 | 2014-01-29 | ワクチン組成物 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2014169281A JP2014169281A (ja) | 2014-09-18 |
JP6473292B2 true JP6473292B2 (ja) | 2019-02-20 |
Family
ID=50028733
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014014809A Expired - Fee Related JP6473292B2 (ja) | 2013-02-05 | 2014-01-29 | ワクチン組成物 |
Country Status (8)
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6512569B2 (ja) * | 2013-02-05 | 2019-05-15 | 日東電工株式会社 | 経皮投与用wt1ペプチド癌ワクチンテープ剤 |
CN103961307B (zh) * | 2013-02-05 | 2019-11-29 | 日东电工株式会社 | 经皮给予用wt1肽癌症疫苗组合物 |
EP3053596B1 (en) * | 2013-10-03 | 2020-05-06 | Nitto Denko Corporation | Mucosal vaccine composition |
US10092642B2 (en) | 2013-10-03 | 2018-10-09 | Nitto Denko Corporation | Mucosal vaccine composition |
US10925936B2 (en) | 2014-09-03 | 2021-02-23 | Nitto Denko Corporation | Vaccine pharmaceutical composition for cell-mediated immunity containing bisphosphonates |
BR112017006599A2 (pt) * | 2014-10-02 | 2017-12-19 | Nitto Denko Corp | composição farmacêutica de vacina para administração transdérmica |
KR101647899B1 (ko) * | 2014-12-31 | 2016-08-12 | (의료)길의료재단 | 헬리코박터 균 감염증 예방 또는 치료용 약학적 조성물 |
US9937223B2 (en) | 2015-01-30 | 2018-04-10 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9744239B2 (en) | 2015-01-30 | 2017-08-29 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9744209B2 (en) | 2015-01-30 | 2017-08-29 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9750785B2 (en) | 2015-01-30 | 2017-09-05 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9687526B2 (en) | 2015-01-30 | 2017-06-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9925233B2 (en) | 2015-01-30 | 2018-03-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
WO2016130616A1 (en) | 2015-02-11 | 2016-08-18 | The Johns Hopkins University | Bacteria over-expressing c-di-amp and therapeutic methods |
EP3247376B1 (en) * | 2015-03-30 | 2021-07-14 | Sunnybrook Research Institute | Treating prostate cancer |
BR112019004896A2 (pt) * | 2016-09-15 | 2019-06-04 | Skintech Life Science Ltd | administração sublingual ou bucal de dim para o tratamento de doenças da pele |
CN113924090A (zh) | 2019-04-04 | 2022-01-11 | 大邱庆北尖端医疗产业振兴财团 | 用于预防或治疗癌症的包含曲美布汀或其药学上可接受的盐作为活性成分的药物组合物 |
WO2020247851A1 (en) * | 2019-06-05 | 2020-12-10 | Global Health Solutions Llc | Transdermal vaccine delivery |
CN113248578B (zh) * | 2020-02-12 | 2022-11-15 | 重庆医科大学 | 新型冠状病毒(2019-nCoV)重组抗原及多克隆抗体 |
JP2023522699A (ja) * | 2020-04-22 | 2023-05-31 | エマージェクス ユーエスエー コーポレーション | コロナウイルスワクチンでコーティングされた微小突起を有する経皮活性剤送達デバイス |
CN113855797B (zh) * | 2021-11-19 | 2023-11-10 | 安徽科技学院 | 一种兽用免疫疫苗的稀释剂及其制备方法 |
CN114767847B (zh) * | 2022-06-22 | 2022-09-23 | 深圳大学 | 新冠重组蛋白疫苗佐剂及其应用 |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL105325A (en) | 1992-04-16 | 1996-11-14 | Minnesota Mining & Mfg | Immunogen/vaccine adjuvant composition |
CA2094217A1 (en) | 1992-04-17 | 1993-10-18 | Yasutaka Igari | Transmucosal therapeutic composition |
JPH069424A (ja) | 1992-04-17 | 1994-01-18 | Takeda Chem Ind Ltd | 経粘膜用製剤 |
JPH10120560A (ja) * | 1996-08-26 | 1998-05-12 | Sankyo Co Ltd | ロキソプロフェン含有外用製剤 |
US6113918A (en) | 1997-05-08 | 2000-09-05 | Ribi Immunochem Research, Inc. | Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors |
US6764840B2 (en) | 1997-05-08 | 2004-07-20 | Corixa Corporation | Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors |
US6303347B1 (en) | 1997-05-08 | 2001-10-16 | Corixa Corporation | Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors |
EP2280031B1 (en) | 1998-07-31 | 2015-04-15 | International Institute of Cancer Immunology, Inc. | Cancer antigens based on products of the tumor suppressor gene WT1 |
IL127331A0 (en) | 1998-11-30 | 1999-09-22 | Yeda Res & Dev | Peptide-based vaccine for influenza |
JP2003516344A (ja) | 1999-12-13 | 2003-05-13 | エピミューン, インコーポレイテッド | Hlaクラスia2腫瘍関連抗原ペプチドおよびワクチン組成物 |
HUP0302068A3 (en) | 2000-07-20 | 2005-05-30 | Lauras As | Use of cox-2 inhibitors for treating or preventing immunodeficiency and pharmaceutical compositions containing them |
EP1496934A4 (en) | 2002-04-19 | 2006-08-02 | Endocyte Inc | IMPROVED IMMUNOTHERAPY BY ADJUVANT |
EP1670513B1 (en) | 2003-10-06 | 2013-01-23 | Cedars-Sinai Medical Center | Cox-2 inhibitors and dendritic cells for use in the treatment of cancer. |
AU2005222626B2 (en) | 2004-03-15 | 2010-05-20 | Karagen Pharmaceuticals, Inc. | A method for inhibiting cancer cell proliferation or increasing cancer cell apoptosis |
EP1731605B1 (en) | 2004-03-31 | 2010-03-24 | International Institute of Cancer Immunology, Inc. | Cancer antigen peptides derived from wt1 |
DE102004049223A1 (de) | 2004-10-08 | 2006-04-20 | Johannes-Gutenberg-Universität Mainz | Zubereitung zum Impfen, Impfverfahren und Verwendung einer Impf-Zubereitung |
WO2008004992A2 (en) * | 2005-05-25 | 2008-01-10 | Tripep Ab | Transdermal formulations containing hepatitis c virus immunogens and an ethoxylated oil |
EP1917976B1 (en) | 2005-08-01 | 2011-03-16 | Hisamitsu Pharmaceutical Co. Inc. | Adjuvant or pharmaceutical preparation for transdermal or transmucosal administration |
AU2007218649B2 (en) | 2006-02-22 | 2013-01-10 | International Institute Of Cancer Immunology, Inc. | HLA-A*3303-restricted WT1 peptide and pharmaceutical composition comprising the same |
US20080112974A1 (en) | 2006-09-08 | 2008-05-15 | Duotol Ab | Method for inducing mucosal humoral and cell-mediated immune responses by sublingual administration of antigens |
DK2479275T3 (en) | 2006-12-28 | 2015-12-14 | Int Inst Cancer Immunology Inc | HLA-A * 1101-restricted WT1 peptide or pharmaceutical composition comprising this |
EP2305292A4 (en) | 2008-08-01 | 2013-02-20 | So Pharmaceutical Corp | TRANSDERMAL IMMUNIZER OF S / O TYPE |
GB201009273D0 (en) * | 2010-06-03 | 2010-07-21 | Glaxosmithkline Biolog Sa | Novel vaccine |
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2014
- 2014-01-29 KR KR1020140011639A patent/KR20140100422A/ko not_active Withdrawn
- 2014-01-29 CN CN201410043652.3A patent/CN103961701B/zh not_active Expired - Fee Related
- 2014-01-29 RU RU2014102945/10A patent/RU2014102945A/ru not_active Application Discontinuation
- 2014-01-29 EP EP14000320.3A patent/EP2762155B1/en active Active
- 2014-01-29 US US14/166,965 patent/US10076491B2/en not_active Expired - Fee Related
- 2014-01-29 JP JP2014014809A patent/JP6473292B2/ja not_active Expired - Fee Related
- 2014-01-29 CA CA2840959A patent/CA2840959A1/en not_active Abandoned
- 2014-01-29 IN IN396CH2014 patent/IN2014CH00396A/en unknown
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KR20140100422A (ko) | 2014-08-14 |
EP2762155B1 (en) | 2020-03-11 |
EP3662927A2 (en) | 2020-06-10 |
CN103961701B (zh) | 2018-09-14 |
US20140220063A1 (en) | 2014-08-07 |
CN103961701A (zh) | 2014-08-06 |
JP2014169281A (ja) | 2014-09-18 |
EP2762155A2 (en) | 2014-08-06 |
EP2762155A3 (en) | 2015-11-04 |
EP3662927A3 (en) | 2020-10-21 |
US10076491B2 (en) | 2018-09-18 |
IN2014CH00396A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2015-04-03 |
RU2014102945A (ru) | 2015-08-10 |
CA2840959A1 (en) | 2014-08-05 |
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