JP6472789B2 - 受容体含有安定化液剤 - Google Patents

受容体含有安定化液剤 Download PDF

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Publication number
JP6472789B2
JP6472789B2 JP2016514046A JP2016514046A JP6472789B2 JP 6472789 B2 JP6472789 B2 JP 6472789B2 JP 2016514046 A JP2016514046 A JP 2016514046A JP 2016514046 A JP2016514046 A JP 2016514046A JP 6472789 B2 JP6472789 B2 JP 6472789B2
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Prior art keywords
receptor
thyroid
stimulating hormone
hormone receptor
amount
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JP2016514046A
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Japanese (ja)
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JP2016520193A (ja
JP2016520193A5 (enExample
Inventor
キアエイ，デイビッド
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Siemens Healthcare Diagnostics Inc
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Siemens Healthcare Diagnostics Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2016514046A 2013-05-14 2014-05-13 受容体含有安定化液剤 Active JP6472789B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361823116P 2013-05-14 2013-05-14
US61/823,116 2013-05-14
PCT/US2014/037909 WO2014186402A1 (en) 2013-05-14 2014-05-13 Stabilized liquid formulations containing receptors

Publications (3)

Publication Number Publication Date
JP2016520193A JP2016520193A (ja) 2016-07-11
JP2016520193A5 JP2016520193A5 (enExample) 2017-06-22
JP6472789B2 true JP6472789B2 (ja) 2019-02-20

Family

ID=51898832

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016514046A Active JP6472789B2 (ja) 2013-05-14 2014-05-13 受容体含有安定化液剤

Country Status (6)

Country Link
US (2) US10203338B2 (enExample)
EP (1) EP2997039B1 (enExample)
JP (1) JP6472789B2 (enExample)
CN (1) CN105209486B (enExample)
ES (1) ES2747634T3 (enExample)
WO (1) WO2014186402A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112189139B (zh) * 2018-09-26 2024-10-29 北卡罗来纳-查佩尔山大学 用于改进测定的化合物、组合物和方法
JP7269906B2 (ja) * 2019-10-29 2023-05-09 三洋化成工業株式会社 免疫測定用試薬、免疫測定用キット及び免疫測定方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4318980A (en) 1978-04-10 1982-03-09 Miles Laboratories, Inc. Heterogenous specific binding assay employing a cycling reactant as label
CA1223831A (en) 1982-06-23 1987-07-07 Dean Engelhardt Modified nucleotides, methods of preparing and utilizing and compositions containing the same
DE3414508A1 (de) 1984-04-13 1985-10-24 Schering AG, 1000 Berlin und 4709 Bergkamen Mehrfach tritiierte steroid-20.17-spirolactone und ihre verwendung als tracersubstanzen
US4711856A (en) 1984-09-19 1987-12-08 Mayo Medical Resources Nuclear binding assay for steroid receptor functionality in cancerous cells
US5089390A (en) 1987-09-04 1992-02-18 Syntex (U.S.A.) Inc. 2-methyl-4-hexene- and 2-methyl-4-heptene-1,2-diol derivatives
US5185243A (en) 1988-08-25 1993-02-09 Syntex (U.S.A.) Inc. Method for detection of specific nucleic acid sequences
US5508178A (en) 1989-01-19 1996-04-16 Rose; Samuel Nucleic acid amplification using single primer
US5340716A (en) 1991-06-20 1994-08-23 Snytex (U.S.A.) Inc. Assay method utilizing photoactivated chemiluminescent label
US6100071A (en) 1996-05-07 2000-08-08 Genentech, Inc. Receptors as novel inhibitors of vascular endothelial growth factor activity and processes for their production
CA2258720A1 (en) * 1996-06-05 1997-12-11 Basil Rapoport Human thyrotropin receptor compositions and use thereof
WO2002077174A2 (en) 2001-03-27 2002-10-03 Zymogenetics, Inc. Human cytokine receptor
DE50306067D1 (de) 2002-11-26 2007-02-01 Brahms Ag Nachweis von tsh-rezeptor-autoantikörpern mit affinitätsgereinigten antikörpern
JP5405111B2 (ja) * 2005-09-26 2014-02-05 ウルリヒ ルース Ｔｓｈ受容体及び新規ｔｓｈ受容体キメラに対する自己免疫抗体検出方法
US20080305098A1 (en) 2005-11-21 2008-12-11 Dr. Fenning Biomed Gmbh Recombinant Polypeptides and Methods for Detecting and/or Quantifying Autoantibodies Against Tsh Receptor
JP5832723B2 (ja) 2009-03-06 2015-12-16 協和メデックス株式会社 可溶性インターロイキン−２受容体定量用標準品
JP2011136911A (ja) 2009-12-25 2011-07-14 Tosoh Corp 甲状腺刺激ホルモンレセプターの安定化方法

Also Published As

Publication number Publication date
JP2016520193A (ja) 2016-07-11
ES2747634T3 (es) 2020-03-11
US20180356428A1 (en) 2018-12-13
CN105209486B (zh) 2021-04-06
US20160084847A1 (en) 2016-03-24
US10203338B2 (en) 2019-02-12
WO2014186402A1 (en) 2014-11-20
CN105209486A (zh) 2015-12-30
EP2997039A1 (en) 2016-03-23
US11119108B2 (en) 2021-09-14
EP2997039B1 (en) 2019-06-26
EP2997039A4 (en) 2016-11-30

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