JP6469655B2 - 代用皮膚および毛包新生の方法 - Google Patents

代用皮膚および毛包新生の方法 Download PDF

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JP6469655B2
JP6469655B2 JP2016512038A JP2016512038A JP6469655B2 JP 6469655 B2 JP6469655 B2 JP 6469655B2 JP 2016512038 A JP2016512038 A JP 2016512038A JP 2016512038 A JP2016512038 A JP 2016512038A JP 6469655 B2 JP6469655 B2 JP 6469655B2
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cells
skin
hair
mesenchymal
human
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JP2016522682A (ja
JP2016522682A5 (enExample
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ラジェシュ・タンガパザム
トーマス・エヌ・ダーリング
シャオウェイ・リー
Original Assignee
ザ ヘンリー エム. ジャクソン ファウンデーション フォー ザ アドヴァンスメント オブ ミリタリー メディシン インコーポレイテッド
ザ ヘンリー エム. ジャクソン ファウンデーション フォー ザ アドヴァンスメント オブ ミリタリー メディシン インコーポレイテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3886Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24Collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3813Epithelial cells, e.g. keratinocytes, urothelial cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60Materials for use in artificial skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/18Materials or treatment for tissue regeneration for hair reconstruction

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2016512038A 2013-05-03 2014-05-01 代用皮膚および毛包新生の方法 Expired - Fee Related JP6469655B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361819332P 2013-05-03 2013-05-03
US61/819,332 2013-05-03
PCT/US2014/036351 WO2014179559A1 (en) 2013-05-03 2014-05-01 Skin substitutes and methods for hair follicle neogenesis

Publications (3)

Publication Number Publication Date
JP2016522682A JP2016522682A (ja) 2016-08-04
JP2016522682A5 JP2016522682A5 (enExample) 2017-06-15
JP6469655B2 true JP6469655B2 (ja) 2019-02-13

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JP2016512038A Expired - Fee Related JP6469655B2 (ja) 2013-05-03 2014-05-01 代用皮膚および毛包新生の方法

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US (1) US10478526B2 (enExample)
EP (1) EP2991692B1 (enExample)
JP (1) JP6469655B2 (enExample)
AU (2) AU2014259787B2 (enExample)
CA (1) CA2910328C (enExample)
WO (1) WO2014179559A1 (enExample)

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EP3117263B1 (en) * 2014-03-14 2018-05-09 Sony Interactive Entertainment Inc. Methods and systems tracking head mounted display (hmd) and calibrations for hmd headband adjustments
KR102251129B1 (ko) 2014-07-09 2021-05-11 샌포드 번햄 프레비즈 메디컬 디스커버리 인스티튜트 모발 성장을 조정하기 위한 방법 및 조성물
JP6782241B2 (ja) 2015-01-12 2020-11-11 ウェイク・フォレスト・ユニヴァーシティ・ヘルス・サイエンシズ 多層皮膚代替製品、ならびにそれを作製および使用する方法
EP3072535B1 (fr) * 2015-03-26 2017-03-01 Université de Bordeaux Procédé de reconstruction de peau
CN108138133B (zh) 2015-10-30 2022-01-11 国立大学法人横滨国立大学 再生毛囊原基的集合体的制造方法、含毛囊组织薄片及含毛囊组织薄片的制造方法
DE102015119877B4 (de) * 2015-11-17 2017-09-21 Technische Universität Berlin Verfahren zur Herstellung eines Hautäquivalents sowie dessen Verwendung für in vitro Tests und in vivo Transplantate
JP2019511919A (ja) * 2016-02-23 2019-05-09 ブローディ,チャヤ がん幹細胞の作製およびその使用
EP3473706B1 (en) * 2016-06-17 2025-09-10 National University Corporation Yokohama National University Cell-embedded beads for hair regeneration and method for producing same, and kit for hair regeneration
SG11201811102XA (en) * 2016-06-21 2019-01-30 Organ Technologies Inc Method for producing artificial skin having hair follicles, sebaceous glands, and pores
CN110167609A (zh) * 2016-11-10 2019-08-23 奥加诺沃公司 生物打印的毛囊及其用途
EP3813952A4 (en) * 2018-05-07 2022-06-08 Reelabs Pvt. Ltd. The method of autologous primary hair follicles preparation in 3d culture
JP7142840B2 (ja) * 2018-05-16 2022-09-28 国立大学法人横浜国立大学 細胞含有ハイドロゲル体及びその製造方法
JP7702229B2 (ja) * 2018-11-19 2025-07-03 株式会社 資生堂 毛包を有するヒト皮膚組織を再構成するための組成物、ヒト皮膚組織モデル動物およびその製造方法
US20220228113A1 (en) * 2019-05-07 2022-07-21 National University Corporation Yokohama National University Hair Follicle Primordia and Method for Producing Same
KR102224079B1 (ko) * 2020-08-31 2021-03-05 한국화학연구원 산업부생가스로부터 일산화탄소 회수 시스템 및 회수 방법
US20240240143A1 (en) * 2021-05-27 2024-07-18 The University Of Hong Kong Bioengineered dermal papilla and hair follicles and related products, methods and applications

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US5693332C1 (en) 1995-08-11 2001-01-09 Univ California Human keratinocytes supported on a hydrophilic membrane and methods of using same to effect wound closure
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Publication number Publication date
CA2910328C (en) 2019-10-22
AU2014259787B2 (en) 2018-03-08
WO2014179559A1 (en) 2014-11-06
EP2991692B1 (en) 2019-08-21
JP2016522682A (ja) 2016-08-04
EP2991692A1 (en) 2016-03-09
AU2018201536B2 (en) 2019-08-22
CA2910328A1 (en) 2014-11-06
US20160184481A1 (en) 2016-06-30
AU2018201536A1 (en) 2018-03-22
AU2014259787A1 (en) 2015-11-12
US10478526B2 (en) 2019-11-19

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