JP6469655B2 - 代用皮膚および毛包新生の方法 - Google Patents

代用皮膚および毛包新生の方法 Download PDF

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JP6469655B2
JP6469655B2 JP2016512038A JP2016512038A JP6469655B2 JP 6469655 B2 JP6469655 B2 JP 6469655B2 JP 2016512038 A JP2016512038 A JP 2016512038A JP 2016512038 A JP2016512038 A JP 2016512038A JP 6469655 B2 JP6469655 B2 JP 6469655B2
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cells
skin
hair
mesenchymal
human
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JP2016522682A (ja
JP2016522682A5 (enExample
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ラジェシュ・タンガパザム
トーマス・エヌ・ダーリング
シャオウェイ・リー
Original Assignee
ザ ヘンリー エム． ジャクソン ファウンデーション フォー ザ アドヴァンスメント オブ ミリタリー メディシン インコーポレイテッド
ザ ヘンリー エム． ジャクソン ファウンデーション フォー ザ アドヴァンスメント オブ ミリタリー メディシン インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3886—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3813—Epithelial cells, e.g. keratinocytes, urothelial cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/18—Materials or treatment for tissue regeneration for hair reconstruction

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2016512038A 2013-05-03 2014-05-01 代用皮膚および毛包新生の方法 Expired - Fee Related JP6469655B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361819332P 2013-05-03 2013-05-03
US61/819,332 2013-05-03
PCT/US2014/036351 WO2014179559A1 (en) 2013-05-03 2014-05-01 Skin substitutes and methods for hair follicle neogenesis

Publications (3)

Publication Number Publication Date
JP2016522682A JP2016522682A (ja) 2016-08-04
JP2016522682A5 JP2016522682A5 (enExample) 2017-06-15
JP6469655B2 true JP6469655B2 (ja) 2019-02-13

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JP2016512038A Expired - Fee Related JP6469655B2 (ja) 2013-05-03 2014-05-01 代用皮膚および毛包新生の方法

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US (1) US10478526B2 (enExample)
EP (1) EP2991692B1 (enExample)
JP (1) JP6469655B2 (enExample)
AU (2) AU2014259787B2 (enExample)
CA (1) CA2910328C (enExample)
WO (1) WO2014179559A1 (enExample)

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JP6377759B2 (ja) * 2014-03-14 2018-08-22 株式会社ソニー・インタラクティブエンタテインメント ヘッドマウントディスプレイ（ｈｍｄ）の追跡及びｈｍｄのヘッドバンドの調整のための校正方法及びシステム
US10716808B2 (en) * 2014-07-09 2020-07-21 Sanford Burnham Prebys Medical Discovery Institute Methods and compositions to modulate hair growth
CA2972094C (en) 2015-01-12 2023-10-24 Wake Forest University Health Sciences Multi-layer skin substitute products and methods of making and using the same
ES2625768T3 (es) * 2015-03-26 2017-07-20 Université De Bordeaux Método de reconstrucción de piel
JP6425319B2 (ja) * 2015-10-30 2018-11-28 国立大学法人横浜国立大学 複数の再生毛包原基の製造方法、毛包組織含有シートの製造方法、毛包組織含有シート及び培養基板の使用
DE102015119877B4 (de) * 2015-11-17 2017-09-21 Technische Universität Berlin Verfahren zur Herstellung eines Hautäquivalents sowie dessen Verwendung für in vitro Tests und in vivo Transplantate
EP3420075A4 (en) 2016-02-23 2019-10-16 Chaya Brodie GENERATION OF CANCER STEM CELLS AND USE THEREOF
EP3473706B1 (en) * 2016-06-17 2025-09-10 National University Corporation Yokohama National University Cell-embedded beads for hair regeneration and method for producing same, and kit for hair regeneration
CA3028357A1 (en) * 2016-06-21 2017-12-28 Organ Technologies, Inc. Method for manufacturing artificial skin having hair follicles, sebaceous glands, and hair pores
KR20190077407A (ko) * 2016-11-10 2019-07-03 오가노보, 인크. 바이오프린팅된 모발 모낭 및 그의 용도
US12234478B2 (en) * 2018-05-07 2025-02-25 Reelabs Pvt. Ltd. Method of autologous primary hair follicles preparation in 3D culture
JP7142840B2 (ja) 2018-05-16 2022-09-28 国立大学法人横浜国立大学 細胞含有ハイドロゲル体及びその製造方法
JP7702229B2 (ja) * 2018-11-19 2025-07-03 株式会社 資生堂 毛包を有するヒト皮膚組織を再構成するための組成物、ヒト皮膚組織モデル動物およびその製造方法
WO2020225934A1 (ja) 2019-05-07 2020-11-12 国立大学法人横浜国立大学 毛包原基及びその製造方法
KR102224079B1 (ko) * 2020-08-31 2021-03-05 한국화학연구원 산업부생가스로부터 일산화탄소 회수 시스템 및 회수 방법
CN117616114A (zh) * 2021-05-27 2024-02-27 香港大学 生物工程真皮乳头和毛囊以及相关产品、方法和应用

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US5693332C1 (en) 1995-08-11 2001-01-09 Univ California Human keratinocytes supported on a hydrophilic membrane and methods of using same to effect wound closure
SE9701162D0 (sv) 1997-03-27 1997-03-27 Karolinska Innovations Ab New use II
US5968546A (en) 1997-05-16 1999-10-19 Baur; Marcus Keratinocyte culture from precursor cells
US5989837A (en) 1998-07-13 1999-11-23 Wisconsin Alumni Research Foundation Immortalized human keratinocyte cell line
BR9915476A (pt) 1998-11-19 2002-01-02 Organogenesis Inc Construtos de tecidos feitos por bioengenharia e métodos para a sua produção e utilização
DE60129799T2 (de) 2000-03-31 2008-04-30 The General Hospital Corp., Boston Verfahren zur steigerung des haarwuchses durch wnt polypeptid
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Publication number Publication date
CA2910328C (en) 2019-10-22
AU2018201536A1 (en) 2018-03-22
AU2014259787A1 (en) 2015-11-12
US10478526B2 (en) 2019-11-19
JP2016522682A (ja) 2016-08-04
AU2018201536B2 (en) 2019-08-22
CA2910328A1 (en) 2014-11-06
WO2014179559A1 (en) 2014-11-06
EP2991692B1 (en) 2019-08-21
EP2991692A1 (en) 2016-03-09
AU2014259787B2 (en) 2018-03-08
US20160184481A1 (en) 2016-06-30

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