JP6433001B2 - 腫瘍細胞へのRNAiトリガーのインビボ送達のためのポリ結合体 - Google Patents

腫瘍細胞へのRNAiトリガーのインビボ送達のためのポリ結合体 Download PDF

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JP6433001B2
JP6433001B2 JP2016533388A JP2016533388A JP6433001B2 JP 6433001 B2 JP6433001 B2 JP 6433001B2 JP 2016533388 A JP2016533388 A JP 2016533388A JP 2016533388 A JP2016533388 A JP 2016533388A JP 6433001 B2 JP6433001 B2 JP 6433001B2
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JP2016535058A (ja
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ウェイジュン チェン
ウェイジュン チェン
ソー ウォン
ソー ウォン
エアロン エム. アルメイダ
エアロン エム. アルメイダ
デイビッド ビー. ロゼマ
デイビッド ビー. ロゼマ
アンドレイ ブイ. ブロッキン
アンドレイ ブイ. ブロッキン
ジェフリー シー. カールソン
ジェフリー シー. カールソン
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アローヘッド ファーマシューティカルズ インコーポレイテッド
アローヘッド ファーマシューティカルズ インコーポレイテッド
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JP2016533388A 2013-08-07 2014-08-06 腫瘍細胞へのRNAiトリガーのインビボ送達のためのポリ結合体 Active JP6433001B2 (ja)

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Application Number Priority Date Filing Date Title
US201361863056P 2013-08-07 2013-08-07
US61/863,056 2013-08-07
US14/452,626 2014-08-06
US14/452,626 US9487556B2 (en) 2013-08-07 2014-08-06 Polyconjugates for delivery of RNAi triggers to tumor cells in vivo
PCT/US2014/049851 WO2015021092A1 (en) 2013-08-07 2014-08-06 Polyconjugates for delivery of rnai triggers to tumor cells in vivo

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JP2016535058A JP2016535058A (ja) 2016-11-10
JP2016535058A5 JP2016535058A5 (enExample) 2016-12-22
JP6433001B2 true JP6433001B2 (ja) 2018-12-05

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EP (1) EP3030244B1 (enExample)
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CN (1) CN105451743B (enExample)
AU (1) AU2014306021B2 (enExample)
CA (1) CA2919088A1 (enExample)
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JP6773677B2 (ja) 2015-03-17 2020-10-21 アローヘッド ファーマシューティカルズ インコーポレイテッド 改善されたジスルフィド含有アルキン連結剤
JP2018509913A (ja) 2015-03-17 2018-04-12 アローヘッド ファーマシューティカルズ インコーポレイテッド 第xii因子の遺伝子発現を阻害するための組成物と方法
WO2016196243A1 (en) 2015-05-29 2016-12-08 Arrowhead Pharmaceuticals, Inc. Biologically cleavable tetrapeptide linking agents
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JP2016535058A (ja) 2016-11-10
MX2016001006A (es) 2016-04-19
TWI685347B (zh) 2020-02-21
TW201601742A (zh) 2016-01-16
EP3030244A4 (en) 2017-06-28
EP3030244B1 (en) 2021-04-21
AU2014306021A1 (en) 2016-01-28
IL243941A0 (en) 2016-04-21
US20190062748A1 (en) 2019-02-28
AU2014306021A2 (en) 2016-11-24
HK1220397A1 (zh) 2017-05-05
US9487556B2 (en) 2016-11-08
EP3030244A1 (en) 2016-06-15
AU2014306021B2 (en) 2018-12-13
IL243941B (en) 2019-06-30
CN105451743A (zh) 2016-03-30
SG11201600379TA (en) 2016-02-26
EA201690051A1 (ru) 2016-06-30
CN105451743B (zh) 2019-11-19
CA2919088A1 (en) 2015-02-12
US20150045573A1 (en) 2015-02-12
WO2015021092A1 (en) 2015-02-12
KR20160035081A (ko) 2016-03-30
US20170022497A1 (en) 2017-01-26

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