JP6430826B2 - 無細胞病原体特異的核酸を検出する方法およびキット - Google Patents

無細胞病原体特異的核酸を検出する方法およびキット Download PDF

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JP6430826B2
JP6430826B2 JP2014502902A JP2014502902A JP6430826B2 JP 6430826 B2 JP6430826 B2 JP 6430826B2 JP 2014502902 A JP2014502902 A JP 2014502902A JP 2014502902 A JP2014502902 A JP 2014502902A JP 6430826 B2 JP6430826 B2 JP 6430826B2
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nucleic acid
cell
target nucleic
free fraction
double
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JP2014510538A (ja
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キアン ミンウェイ
キアン ミンウェイ
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Occam Biolabs Inc
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
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  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
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  • Molecular Biology (AREA)
  • Biotechnology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2014502902A 2011-04-01 2012-04-02 無細胞病原体特異的核酸を検出する方法およびキット Expired - Fee Related JP6430826B2 (ja)

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US201161470774P 2011-04-01 2011-04-01
US61/470,774 2011-04-01
PCT/US2012/031814 WO2012135815A2 (en) 2011-04-01 2012-04-02 Methods and kits for detecting cell-free pathogen-specific nucleic acids

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JP2014510538A JP2014510538A (ja) 2014-05-01
JP6430826B2 true JP6430826B2 (ja) 2018-11-28

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JP2018091537A Pending JP2018117645A (ja) 2011-04-01 2018-05-10 無細胞病原体特異的核酸を検出する方法およびキット

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US (2) US20140147851A1 (enExample)
EP (1) EP2694680A4 (enExample)
JP (2) JP6430826B2 (enExample)
CN (2) CN109280713A (enExample)
AU (3) AU2012236109A1 (enExample)
RU (1) RU2644672C2 (enExample)
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RU2729113C2 (ru) 2014-11-21 2020-08-04 Оккам Байолэбс, Инк. Система и способ сбора образца нуклеиновой кислоты
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US11266337B2 (en) 2015-09-09 2022-03-08 Drawbridge Health, Inc. Systems, methods, and devices for sample collection, stabilization and preservation
EP3141612A1 (en) 2015-09-10 2017-03-15 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Method and device for nucleic acid based diagnostic approaches including the determination of a deviant condtion, especially a health condition and/or pathogenic condition of a sample
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CN105296661A (zh) * 2015-12-02 2016-02-03 北京市结核病胸部肿瘤研究所 通过检测游离核酸诊断结核病的试剂盒及其应用
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CN110312800B (zh) * 2016-11-11 2025-01-10 生物辐射实验室股份有限公司 处理核酸样本的方法
AU2018211530B2 (en) * 2017-01-30 2022-09-15 Safeguard Biosystems Holdings Ltd. Bead beating tube and method for extracting deoxyribonucleic acid and/or ribonucleic acid from microorganisms
EP3610034B1 (en) 2017-04-12 2022-06-08 Karius, Inc. Sample preparation methods, systems and compositions
CN108165563B (zh) * 2017-12-01 2021-02-19 北京蛋白质组研究中心 结核分枝杆菌H37Rv编码基因及其应用
CN108165560B (zh) * 2017-12-01 2021-06-08 北京蛋白质组研究中心 结核分枝杆菌H37Rv编码基因及其应用
CN108165562B (zh) * 2017-12-01 2021-06-08 北京蛋白质组研究中心 结核分枝杆菌H37Rv编码基因及其应用
CN108165561B (zh) * 2017-12-01 2021-06-18 北京蛋白质组研究中心 结核分枝杆菌H37Rv编码基因及其应用
WO2019178157A1 (en) 2018-03-16 2019-09-19 Karius, Inc. Sample series to differentiate target nucleic acids from contaminant nucleic acids
EP3884065B1 (en) 2018-11-21 2024-08-14 Karius, Inc. Direct-to-library methods, systems, and compositions
CN111876411A (zh) * 2019-09-06 2020-11-03 深圳微伴生物有限公司 获得cfDNA标准品的引物组、PCR扩增阳性标准品及其制备方法、试剂盒及应用
KR102286570B1 (ko) * 2019-11-19 2021-08-05 대한민국 소변 시료를 이용하여 결핵 진단용 프라이머, 프로브, 키트 및 이들의 용도
CN114480691A (zh) * 2022-01-24 2022-05-13 广州迪澳基因科技有限公司 基于熔解曲线检测结核分枝杆菌复合菌群的方法及试剂盒

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JP2018117645A (ja) * 2011-04-01 2018-08-02 オッカム・バイオラブズ・インコーポレイテッドOccam Biolabs, Inc. 無細胞病原体特異的核酸を検出する方法およびキット

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RU2644672C2 (ru) 2018-02-13
RU2013148806A (ru) 2015-05-10
CN103814139B (zh) 2018-11-13
US20170369932A1 (en) 2017-12-28
AU2019204844A1 (en) 2019-07-25
WO2012135815A3 (en) 2012-12-27
AU2012236109A1 (en) 2013-11-21
CN103814139A (zh) 2014-05-21
EP2694680A2 (en) 2014-02-12
CN109280713A (zh) 2019-01-29
JP2014510538A (ja) 2014-05-01
AU2017203071A1 (en) 2017-06-01
US20140147851A1 (en) 2014-05-29
JP2018117645A (ja) 2018-08-02
WO2012135815A2 (en) 2012-10-04
EP2694680A4 (en) 2014-09-10

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