JP6429292B2 - Ｈｅｒ２増幅性癌の処置のための方法 - Google Patents

Ｈｅｒ２増幅性癌の処置のための方法 Download PDF

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Publication number
JP6429292B2
JP6429292B2 JP2016534804A JP2016534804A JP6429292B2 JP 6429292 B2 JP6429292 B2 JP 6429292B2 JP 2016534804 A JP2016534804 A JP 2016534804A JP 2016534804 A JP2016534804 A JP 2016534804A JP 6429292 B2 JP6429292 B2 JP 6429292B2
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cancer
her2
ibrutinib
amplifying
day
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JP2016528251A (ja
JP2016528251A5 (enExample
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チェン，ジュン
バギー，ジョセフ，ジェイ．
イライアス，ローレンス
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ファーマサイクリックス エルエルシー
ファーマサイクリックス エルエルシー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2016534804A 2013-08-12 2014-08-12 Ｈｅｒ２増幅性癌の処置のための方法 Expired - Fee Related JP6429292B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361865059P 2013-08-12 2013-08-12
US61/865,059 2013-08-12
US201461969003P 2014-03-21 2014-03-21
US61/969,003 2014-03-21
PCT/US2014/050783 WO2015023703A1 (en) 2013-08-12 2014-08-12 Methods for the treatment of her2 amplified cancer

Related Child Applications (1)

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JP2018201232A Division JP2019031546A (ja) 2013-08-12 2018-10-25 Ｈｅｒ２増幅性癌の処置のための方法

Publications (3)

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JP2016528251A JP2016528251A (ja) 2016-09-15
JP2016528251A5 JP2016528251A5 (enExample) 2017-09-21
JP6429292B2 true JP6429292B2 (ja) 2018-11-28

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JP2016534804A Expired - Fee Related JP6429292B2 (ja) 2013-08-12 2014-08-12 Ｈｅｒ２増幅性癌の処置のための方法
JP2018201232A Ceased JP2019031546A (ja) 2013-08-12 2018-10-25 Ｈｅｒ２増幅性癌の処置のための方法
JP2020156557A Pending JP2021008475A (ja) 2013-08-12 2020-09-17 Ｈｅｒ２増幅性癌の処置のための方法

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JP2018201232A Ceased JP2019031546A (ja) 2013-08-12 2018-10-25 Ｈｅｒ２増幅性癌の処置のための方法
JP2020156557A Pending JP2021008475A (ja) 2013-08-12 2020-09-17 Ｈｅｒ２増幅性癌の処置のための方法

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US (5) US9415050B2 (enExample)
EP (1) EP3033079B1 (enExample)
JP (3) JP6429292B2 (enExample)
CA (1) CA2920534A1 (enExample)
ES (1) ES2709509T3 (enExample)
WO (1) WO2015023703A1 (enExample)

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JP2021008475A (ja) * 2013-08-12 2021-01-28 ファーマサイクリックス エルエルシー Ｈｅｒ２増幅性癌の処置のための方法

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JP2018522028A (ja) * 2015-07-31 2018-08-09 ファーマサイクリックス エルエルシー ブルトン型チロシンキナーゼ阻害剤の組み合わせ及びそれらの使用
KR102075886B1 (ko) * 2015-09-01 2020-02-11 다이호야쿠힌고교 가부시키가이샤 신규한 피라졸로[3,4-d]피리미딘 화합물 또는 그 염
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TWI798334B (zh) 2018-01-31 2023-04-11 大陸商迪哲（江蘇）醫藥股份有限公司 Ｅｒｂｂ／ｂｔｋ抑制劑
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