JP6357228B2 - 高い弾性を有するヒアルロナンの組成物およびその使用 - Google Patents

高い弾性を有するヒアルロナンの組成物およびその使用 Download PDF

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Publication number
JP6357228B2
JP6357228B2 JP2016525455A JP2016525455A JP6357228B2 JP 6357228 B2 JP6357228 B2 JP 6357228B2 JP 2016525455 A JP2016525455 A JP 2016525455A JP 2016525455 A JP2016525455 A JP 2016525455A JP 6357228 B2 JP6357228 B2 JP 6357228B2
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composition
hyaluronan
joint
measured
frequency
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JP2016526573A (ja
Inventor
エンドレ エー． バラージュ，
エンドレ エー． バラージュ，
カルロス ベルモンテ，
カルロス ベルモンテ，
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マトリックス バイオロジー インスティテュート
マトリックス バイオロジー インスティテュート
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2016525455A 2013-07-10 2014-07-09 高い弾性を有するヒアルロナンの組成物およびその使用 Active JP6357228B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361844645P 2013-07-10 2013-07-10
US61/844,645 2013-07-10
PCT/US2014/045973 WO2015006460A1 (en) 2013-07-10 2014-07-09 Compositions of hyaluronan with high elasticity and uses thereof

Related Child Applications (1)

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JP2018114766A Division JP6598929B2 (ja) 2013-07-10 2018-06-15 高い弾性を有するヒアルロナンの組成物およびその使用

Publications (2)

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JP2016526573A JP2016526573A (ja) 2016-09-05
JP6357228B2 true JP6357228B2 (ja) 2018-07-11

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JP2016525455A Active JP6357228B2 (ja) 2013-07-10 2014-07-09 高い弾性を有するヒアルロナンの組成物およびその使用
JP2018114766A Active JP6598929B2 (ja) 2013-07-10 2018-06-15 高い弾性を有するヒアルロナンの組成物およびその使用
JP2019181618A Active JP7025039B2 (ja) 2013-07-10 2019-10-01 高い弾性を有するヒアルロナンの組成物およびその使用
JP2022015509A Withdrawn JP2022058871A (ja) 2013-07-10 2022-02-03 高い弾性を有するヒアルロナンの組成物およびその使用
JP2024010878A Pending JP2024028669A (ja) 2013-07-10 2024-01-29 高い弾性を有するヒアルロナンの組成物およびその使用

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JP2018114766A Active JP6598929B2 (ja) 2013-07-10 2018-06-15 高い弾性を有するヒアルロナンの組成物およびその使用
JP2019181618A Active JP7025039B2 (ja) 2013-07-10 2019-10-01 高い弾性を有するヒアルロナンの組成物およびその使用
JP2022015509A Withdrawn JP2022058871A (ja) 2013-07-10 2022-02-03 高い弾性を有するヒアルロナンの組成物およびその使用
JP2024010878A Pending JP2024028669A (ja) 2013-07-10 2024-01-29 高い弾性を有するヒアルロナンの組成物およびその使用

Country Status (8)

Country Link
US (5) US9492474B2 (enExample)
EP (3) EP3019177B1 (enExample)
JP (5) JP6357228B2 (enExample)
AR (2) AR096875A1 (enExample)
ES (2) ES2837626T3 (enExample)
PL (2) PL3613423T3 (enExample)
PT (2) PT3019177T (enExample)
WO (1) WO2015006460A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
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US9492474B2 (en) 2013-07-10 2016-11-15 Matrix Biology Institute Compositions of hyaluronan with high elasticity and uses thereof
PT3842047T (pt) * 2015-09-24 2024-09-19 Matrix Biology Inst Composições de hialuronano de elevada elasticidade e processos para o seu uso
WO2020144372A1 (en) 2019-01-10 2020-07-16 The Provost, Fellows, Scholars And Other Members Of Board Of Trinity College Dublin Composite viscoelastic hydrogel, and uses thereof for sealing a channel in tissue
EP4368217A3 (en) 2018-01-10 2024-07-31 The Provost, Fellows, Scholars and other Members of Board of Trinity College Dublin System and methods for sealing a channel in tissue
WO2019202017A1 (en) 2018-04-18 2019-10-24 i.com medical GmbH High molecular weight hyaluronic acid for treatment and prevention of severe ocular surface disease
US12268706B2 (en) 2019-01-31 2025-04-08 i.com medical GmbH Hyaluronic acid for relief of idiopathic ocular pain
EP3969057B1 (en) * 2019-05-17 2025-12-17 The Governing Council of the University of Toronto Sustained release local anesthetic hydrogel composition

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WO2015077736A1 (en) 2013-11-25 2015-05-28 Deuteria Biomaterials, Llc Deuterium-enriched hyaluronan
FR3015290B1 (fr) 2013-12-23 2017-01-13 Lab Vivacy Compositions d'acide hyaluronique compreant de la mepivacaine
PT3842047T (pt) 2015-09-24 2024-09-19 Matrix Biology Inst Composições de hialuronano de elevada elasticidade e processos para o seu uso

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US11524027B2 (en) 2022-12-13
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JP2022058871A (ja) 2022-04-12
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US20150018303A1 (en) 2015-01-15
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