JP6342842B2 - 走査型顕微鏡システム - Google Patents
走査型顕微鏡システム Download PDFInfo
- Publication number
- JP6342842B2 JP6342842B2 JP2015093223A JP2015093223A JP6342842B2 JP 6342842 B2 JP6342842 B2 JP 6342842B2 JP 2015093223 A JP2015093223 A JP 2015093223A JP 2015093223 A JP2015093223 A JP 2015093223A JP 6342842 B2 JP6342842 B2 JP 6342842B2
- Authority
- JP
- Japan
- Prior art keywords
- confocal
- microscope system
- observation object
- plate
- lens array
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 230000003287 optical effect Effects 0.000 claims description 67
- 238000003384 imaging method Methods 0.000 claims description 34
- 230000001678 irradiating effect Effects 0.000 claims description 6
- 230000005284 excitation Effects 0.000 description 21
- 238000010586 diagram Methods 0.000 description 16
- 238000012545 processing Methods 0.000 description 14
- 238000005286 illumination Methods 0.000 description 9
- 238000000034 method Methods 0.000 description 6
- 230000000903 blocking effect Effects 0.000 description 4
- 238000001514 detection method Methods 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 239000013307 optical fiber Substances 0.000 description 4
- 239000000758 substrate Substances 0.000 description 4
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 238000009987 spinning Methods 0.000 description 3
- 238000004624 confocal microscopy Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 2
- 229910052753 mercury Inorganic materials 0.000 description 2
- 238000004621 scanning probe microscopy Methods 0.000 description 2
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 description 1
- 238000003491 array Methods 0.000 description 1
- 239000012472 biological sample Substances 0.000 description 1
- 229910052804 chromium Inorganic materials 0.000 description 1
- 239000011651 chromium Substances 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 238000000151 deposition Methods 0.000 description 1
- 238000001917 fluorescence detection Methods 0.000 description 1
- 238000002073 fluorescence micrograph Methods 0.000 description 1
- 239000004973 liquid crystal related substance Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 229910044991 metal oxide Inorganic materials 0.000 description 1
- 150000004706 metal oxides Chemical class 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 230000004304 visual acuity Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0032—Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0036—Scanning details, e.g. scanning stages
- G02B21/0044—Scanning details, e.g. scanning stages moving apertures, e.g. Nipkow disks, rotating lens arrays
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Microscoopes, Condenser (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015093223A JP6342842B2 (ja) | 2015-04-30 | 2015-04-30 | 走査型顕微鏡システム |
| US15/132,698 US10191263B2 (en) | 2015-04-30 | 2016-04-19 | Scanning microscopy system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015093223A JP6342842B2 (ja) | 2015-04-30 | 2015-04-30 | 走査型顕微鏡システム |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016212154A JP2016212154A (ja) | 2016-12-15 |
| JP2016212154A5 JP2016212154A5 (enExample) | 2017-12-28 |
| JP6342842B2 true JP6342842B2 (ja) | 2018-06-13 |
Family
ID=57204804
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015093223A Active JP6342842B2 (ja) | 2015-04-30 | 2015-04-30 | 走査型顕微鏡システム |
Country Status (2)
| Country | Link |
|---|---|
| US (1) | US10191263B2 (enExample) |
| JP (1) | JP6342842B2 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6447148B2 (ja) * | 2015-01-09 | 2019-01-09 | 株式会社ブイ・テクノロジー | 投影露光装置 |
| EP4465115A3 (en) | 2016-09-27 | 2025-02-12 | Intuitive Surgical Operations, Inc. | Micro optic assemblies and optical interrogation systems |
| JP6784603B2 (ja) * | 2017-01-05 | 2020-11-11 | 東レエンジニアリング株式会社 | 分光測定方法および分光測定装置 |
| WO2018226836A1 (en) * | 2017-06-06 | 2018-12-13 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Multi-focal structured illumination microscopy systems and methods |
| US11086113B2 (en) | 2017-06-06 | 2021-08-10 | The United States Of America | Multi-focal structured illumination microscopy systems and methods |
| JP7256604B2 (ja) * | 2018-03-16 | 2023-04-12 | 株式会社ディスコ | 非破壊検出方法 |
| JP7134727B2 (ja) * | 2018-06-13 | 2022-09-12 | 横河電機株式会社 | ディスク走査型顕微鏡 |
| US11543640B2 (en) * | 2020-04-21 | 2023-01-03 | Laxco Incorporated | Confocal optical system and components thereof |
| DE102022108448B3 (de) * | 2022-04-07 | 2023-05-04 | Till I.D. Gmbh | Superauflösende Mikroskopvorrichtung mit rotierender Scheibe |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3327432B2 (ja) * | 1994-10-11 | 2002-09-24 | 横河電機株式会社 | 共焦点光スキャナ |
| JP3350918B2 (ja) * | 1996-03-26 | 2002-11-25 | 株式会社高岳製作所 | 2次元配列型共焦点光学装置 |
| JP3159006B2 (ja) * | 1995-11-10 | 2001-04-23 | 横河電機株式会社 | 共焦点光スキャナ |
| JP3816632B2 (ja) * | 1997-05-14 | 2006-08-30 | オリンパス株式会社 | 走査型顕微鏡 |
| JP5000839B2 (ja) | 2000-09-18 | 2012-08-15 | ヴァンサン・ロウエ | 共焦点用光学走査装置 |
| FR2826736A1 (fr) | 2001-06-28 | 2003-01-03 | Vincent Lauer | Dispositif a balayage optique confocal |
| US6639201B2 (en) * | 2001-11-07 | 2003-10-28 | Applied Materials, Inc. | Spot grid array imaging system |
| US6934079B2 (en) * | 2002-05-03 | 2005-08-23 | Max-Planck-Gesellschaft zur Förderung der Wissen-schaften e. V. | Confocal microscope comprising two microlens arrays and a pinhole diaphragm array |
| JP2004239627A (ja) * | 2003-02-03 | 2004-08-26 | Olympus Corp | 分光器及びこれを備えた共焦点顕微鏡 |
| US7142340B2 (en) | 2003-10-31 | 2006-11-28 | Hewlett-Packard Development Company, L.P. | Optical scanner apparatuses and optical scanning methods |
| DE102007009551B3 (de) | 2007-02-27 | 2008-08-21 | Ludwig-Maximilian-Universität | Vorrichtung für die konfokale Beleuchtung einer Probe |
| EP2225598A1 (en) * | 2007-12-21 | 2010-09-08 | Koninklijke Philips Electronics N.V. | Scanning microscope and method of imaging a sample. |
| JP2011085759A (ja) * | 2009-10-15 | 2011-04-28 | Yokogawa Electric Corp | 共焦点光スキャナ |
| JP5495740B2 (ja) * | 2009-12-02 | 2014-05-21 | オリンパス株式会社 | 共焦点走査型顕微鏡 |
| JP5412394B2 (ja) * | 2010-09-30 | 2014-02-12 | オリンパス株式会社 | 標本観察装置 |
| JP5955574B2 (ja) * | 2012-02-03 | 2016-07-20 | 株式会社東光高岳 | 立体形状計測装置 |
| WO2013126762A1 (en) | 2012-02-23 | 2013-08-29 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Office Of Technology Transfer, National Institutes Of Health | Multi-focal structured illumination microscopy systems and methods |
| DE102013001238B4 (de) * | 2013-01-25 | 2020-06-10 | Carl Zeiss Microscopy Gmbh | Lichtmikroskop und Mikroskopieverfahren |
| DE102013005563A1 (de) | 2013-03-28 | 2014-10-02 | Carl Zeiss Microscopy Gmbh | Lichtmikroskop und verfahren zum untersuchen einer mikroskopischen probe |
| US20150131148A1 (en) * | 2013-11-12 | 2015-05-14 | Intelligent Imaging Innovations, Inc. | Spinning disk confocal using paired microlens disks |
| JP5999121B2 (ja) * | 2014-02-17 | 2016-09-28 | 横河電機株式会社 | 共焦点光スキャナ |
| JP6090607B2 (ja) * | 2014-12-08 | 2017-03-08 | 横河電機株式会社 | 共焦点スキャナ、共焦点顕微鏡 |
| US9766442B2 (en) | 2014-12-08 | 2017-09-19 | Yokogawa Electric Corporation | Confocal scanner and confocal microscope |
-
2015
- 2015-04-30 JP JP2015093223A patent/JP6342842B2/ja active Active
-
2016
- 2016-04-19 US US15/132,698 patent/US10191263B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2016212154A (ja) | 2016-12-15 |
| US20160320596A1 (en) | 2016-11-03 |
| US10191263B2 (en) | 2019-01-29 |
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