JP6305345B2 - 鉄および関連する薬学的製剤のバイオアベイラビリティを増加させることによる障害の予防または治療方法 - Google Patents

鉄および関連する薬学的製剤のバイオアベイラビリティを増加させることによる障害の予防または治療方法 Download PDF

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JP6305345B2
JP6305345B2 JP2014546468A JP2014546468A JP6305345B2 JP 6305345 B2 JP6305345 B2 JP 6305345B2 JP 2014546468 A JP2014546468 A JP 2014546468A JP 2014546468 A JP2014546468 A JP 2014546468A JP 6305345 B2 JP6305345 B2 JP 6305345B2
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lipocalin mutein
hepcidin
iron
lipocalin
mutein
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JP2015501822A5 (enExample
JP2015501822A (ja
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アンドレアス ホールバウム
アンドレアス ホールバウム
ヘンドリック ジル
ヘンドリック ジル
ステファン トレントマン
ステファン トレントマン
ローレント オドリ
ローレント オドリ
アンドレア アレアシュドルファー
アンドレア アレアシュドルファー
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ピエリス ファーマシューティカルズ ゲーエムベーハー
ピエリス ファーマシューティカルズ ゲーエムベーハー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy

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JP2014546468A 2011-12-12 2012-12-12 鉄および関連する薬学的製剤のバイオアベイラビリティを増加させることによる障害の予防または治療方法 Expired - Fee Related JP6305345B2 (ja)

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US201161569501P 2011-12-12 2011-12-12
US61/569,501 2011-12-12
US201261599152P 2012-02-15 2012-02-15
US61/599,152 2012-02-15
PCT/EP2012/075135 WO2013087654A2 (en) 2011-12-12 2012-12-12 Methods for preventing or treating disorders by increasing bioavailability of iron and related pharmaceutical formulation

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JP2018039343A Division JP2018118980A (ja) 2011-12-12 2018-03-06 鉄および関連する薬学的製剤のバイオアベイラビリティを増加させることによる障害の予防または治療方法

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JP2018039343A Pending JP2018118980A (ja) 2011-12-12 2018-03-06 鉄および関連する薬学的製剤のバイオアベイラビリティを増加させることによる障害の予防または治療方法

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CN105726543A (zh) * 2016-02-22 2016-07-06 浙江大学 腺嘌呤在制备调控hepcidin表达药物中的应用
CN114594268A (zh) 2016-03-29 2022-06-07 无限生物制药公司 用以预防或治疗肾脏疾病的活性组分的候选物质的筛选装置和筛选方法
CN109641954A (zh) * 2016-08-29 2019-04-16 里珍纳龙药品有限公司 抗-gremlin-1(grem1)抗体及其用于治疗肺动脉高血压的使用方法
CN113939307A (zh) 2019-03-29 2022-01-14 皮里斯制药有限公司 脂质运载蛋白突变蛋白的吸入施用
CA3156007A1 (en) 2019-09-27 2021-04-01 Disc Medicine, Inc. METHODS OF TREATING MYELOFIBROSE AND ASSOCIATED CONDITIONS
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AU2021273014A1 (en) 2020-05-13 2022-11-17 AbbVie Deutschland GmbH & Co. KG Anti-hemojuvelin (HJV) antibodies for treating anemia of chronic disease
ES3075793T3 (en) 2020-05-13 2026-08-07 Disc Medicine Inc Anti-hemojuvelin (hjv) antibodies for treating myelofibrosis
WO2022098812A1 (en) 2020-11-04 2022-05-12 Keros Therapeutics, Inc. Methods of treating iron overload
JP2023117892A (ja) * 2022-02-14 2023-08-24 公益財団法人 鷹揚郷 ヘプシジン結合ペプチド

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US20170224770A1 (en) 2017-08-10
US9610356B2 (en) 2017-04-04
EP3309555A3 (en) 2018-05-30
EP3309555A2 (en) 2018-04-18
SG10201604574UA (en) 2016-07-28
EP2791684A2 (en) 2014-10-22
US9950034B2 (en) 2018-04-24
WO2013087654A3 (en) 2013-09-12
US20140323389A1 (en) 2014-10-30
CN103998937A (zh) 2014-08-20
JP2018118980A (ja) 2018-08-02
WO2013087654A2 (en) 2013-06-20
US20180311311A1 (en) 2018-11-01
JP2015501822A (ja) 2015-01-19
SG11201402996WA (en) 2014-07-30
CA2858959A1 (en) 2013-06-20
AU2012350654B2 (en) 2017-12-14
EP2791684B1 (en) 2017-08-23
AU2012350654C1 (en) 2018-05-10
AU2012350654A1 (en) 2014-07-03

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