CN103998937A - 通过提高铁的生物利用度来预防或治疗障碍的方法及相关的药物制剂 - Google Patents
通过提高铁的生物利用度来预防或治疗障碍的方法及相关的药物制剂 Download PDFInfo
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- CN103998937A CN103998937A CN201280061110.8A CN201280061110A CN103998937A CN 103998937 A CN103998937 A CN 103998937A CN 201280061110 A CN201280061110 A CN 201280061110A CN 103998937 A CN103998937 A CN 103998937A
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- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/34—Genitourinary disorders
- G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
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- Animal Behavior & Ethology (AREA)
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- Immunology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
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- Diabetes (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
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| US201161569501P | 2011-12-12 | 2011-12-12 | |
| US61/569,501 | 2011-12-12 | ||
| US201261599152P | 2012-02-15 | 2012-02-15 | |
| US61/599,152 | 2012-02-15 | ||
| PCT/EP2012/075135 WO2013087654A2 (en) | 2011-12-12 | 2012-12-12 | Methods for preventing or treating disorders by increasing bioavailability of iron and related pharmaceutical formulation |
Publications (1)
| Publication Number | Publication Date |
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| CN103998937A true CN103998937A (zh) | 2014-08-20 |
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| CN201280061110.8A Pending CN103998937A (zh) | 2011-12-12 | 2012-12-12 | 通过提高铁的生物利用度来预防或治疗障碍的方法及相关的药物制剂 |
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| US (3) | US9610356B2 (enExample) |
| EP (2) | EP2791684B1 (enExample) |
| JP (2) | JP6305345B2 (enExample) |
| CN (1) | CN103998937A (enExample) |
| AU (1) | AU2012350654C1 (enExample) |
| CA (1) | CA2858959A1 (enExample) |
| DK (1) | DK2791684T3 (enExample) |
| SG (2) | SG11201402996WA (enExample) |
| WO (1) | WO2013087654A2 (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105168209A (zh) * | 2015-09-21 | 2015-12-23 | 浙江大学 | HDAC1抑制剂在制备调控hepcidin表达药物中的应用 |
| CN105726543A (zh) * | 2016-02-22 | 2016-07-06 | 浙江大学 | 腺嘌呤在制备调控hepcidin表达药物中的应用 |
| CN109641954A (zh) * | 2016-08-29 | 2019-04-16 | 里珍纳龙药品有限公司 | 抗-gremlin-1(grem1)抗体及其用于治疗肺动脉高血压的使用方法 |
| CN114686584A (zh) * | 2016-03-29 | 2022-07-01 | 无限生物制药公司 | 用以预防或治疗肾脏疾病的活性组分的候选物质的筛选装置和筛选方法 |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113939307A (zh) * | 2019-03-29 | 2022-01-14 | 皮里斯制药有限公司 | 脂质运载蛋白突变蛋白的吸入施用 |
| KR20220088699A (ko) | 2019-09-27 | 2022-06-28 | 디스크 메디슨, 인크. | 골수섬유증 및 관련 상태의 치료 방법 |
| KR20230012539A (ko) | 2020-05-13 | 2023-01-26 | 디스크 메디슨, 인크. | 골수섬유증을 치료하기 위한 항-헤모주벨린 (hjv) 항체 |
| WO2022098812A1 (en) | 2020-11-04 | 2022-05-12 | Keros Therapeutics, Inc. | Methods of treating iron overload |
| JP2023117892A (ja) * | 2022-02-14 | 2023-08-24 | 公益財団法人 鷹揚郷 | ヘプシジン結合ペプチド |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008097461A2 (en) * | 2007-02-02 | 2008-08-14 | Amgen Inc | Hepcidin and hepcidin antibodies |
| WO2010111254A1 (en) * | 2009-03-25 | 2010-09-30 | Genentech, Inc. | Novel anti-alpha5beta1 antibodies and uses thereof |
| WO2011143232A1 (en) * | 2010-05-10 | 2011-11-17 | Westerman Mark E | Markers for acute kidney injury |
| WO2011149962A1 (en) * | 2010-05-24 | 2011-12-01 | The Trustees Of Columbia University In The City Of New York | Mutant ngal proteins and uses thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19742706B4 (de) | 1997-09-26 | 2013-07-25 | Pieris Proteolab Ag | Lipocalinmuteine |
| DE19926068C1 (de) | 1999-06-08 | 2001-01-11 | Arne Skerra | Muteine des Bilin-Bindungsproteins |
| EP1430136A1 (en) | 2001-09-27 | 2004-06-23 | Pieris ProteoLab AG | Muteins of apolipoprotein d |
| WO2003029462A1 (en) | 2001-09-27 | 2003-04-10 | Pieris Proteolab Ag | Muteins of human neutrophil gelatinase-associated lipocalin and related proteins |
| WO2005019255A1 (en) | 2003-08-25 | 2005-03-03 | Pieris Proteolab Ag | Muteins of tear lipocalin |
| EP1996613B1 (en) * | 2006-03-20 | 2014-04-30 | Technische Universität München | Muteins of tear lipocalin with affinity for the t-cell coreceptor cd4 |
| AU2007275638B2 (en) | 2006-07-21 | 2014-01-16 | Amgen Inc. | Method of detecting and/ or measuring hepcidin in a sample |
| AR069062A1 (es) | 2007-11-02 | 2009-12-23 | Lilly Co Eli | Anticuerpo anti-hepcidina |
| CA2711826C (en) | 2008-01-25 | 2018-02-27 | Amgen Inc. | Ferroportin antibodies and methods of use |
| EP2816059A1 (en) | 2008-05-01 | 2014-12-24 | Amgen, Inc | Anti-hepcidin antibodies and methods of use |
| ES2432018T3 (es) | 2008-08-06 | 2013-11-29 | Eli Lilly And Company | Anticuerpos selectivos anti-hepcidina-25 y usos de los mismos |
| US20110268818A1 (en) | 2008-09-18 | 2011-11-03 | Jonathan Barasch | Ngal-binding siderophores and use thereof to treat iron deficiency and iron overload |
| CA2808392C (en) | 2010-08-16 | 2020-03-10 | Pieris Ag | Binding proteins for hepcidin |
-
2012
- 2012-12-12 US US14/364,465 patent/US9610356B2/en not_active Expired - Fee Related
- 2012-12-12 WO PCT/EP2012/075135 patent/WO2013087654A2/en not_active Ceased
- 2012-12-12 EP EP12813294.1A patent/EP2791684B1/en not_active Not-in-force
- 2012-12-12 JP JP2014546468A patent/JP6305345B2/ja not_active Expired - Fee Related
- 2012-12-12 SG SG11201402996WA patent/SG11201402996WA/en unknown
- 2012-12-12 AU AU2012350654A patent/AU2012350654C1/en not_active Ceased
- 2012-12-12 EP EP17187016.5A patent/EP3309555A3/en not_active Withdrawn
- 2012-12-12 SG SG10201604574UA patent/SG10201604574UA/en unknown
- 2012-12-12 CN CN201280061110.8A patent/CN103998937A/zh active Pending
- 2012-12-12 DK DK12813294.1T patent/DK2791684T3/da active
- 2012-12-12 CA CA2858959A patent/CA2858959A1/en not_active Abandoned
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2017
- 2017-02-16 US US15/435,146 patent/US9950034B2/en not_active Expired - Fee Related
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2018
- 2018-03-06 JP JP2018039343A patent/JP2018118980A/ja active Pending
- 2018-03-28 US US15/938,117 patent/US20180311311A1/en not_active Abandoned
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008097461A2 (en) * | 2007-02-02 | 2008-08-14 | Amgen Inc | Hepcidin and hepcidin antibodies |
| WO2010111254A1 (en) * | 2009-03-25 | 2010-09-30 | Genentech, Inc. | Novel anti-alpha5beta1 antibodies and uses thereof |
| WO2011143232A1 (en) * | 2010-05-10 | 2011-11-17 | Westerman Mark E | Markers for acute kidney injury |
| WO2011149962A1 (en) * | 2010-05-24 | 2011-12-01 | The Trustees Of Columbia University In The City Of New York | Mutant ngal proteins and uses thereof |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105168209A (zh) * | 2015-09-21 | 2015-12-23 | 浙江大学 | HDAC1抑制剂在制备调控hepcidin表达药物中的应用 |
| CN105726543A (zh) * | 2016-02-22 | 2016-07-06 | 浙江大学 | 腺嘌呤在制备调控hepcidin表达药物中的应用 |
| CN114686584A (zh) * | 2016-03-29 | 2022-07-01 | 无限生物制药公司 | 用以预防或治疗肾脏疾病的活性组分的候选物质的筛选装置和筛选方法 |
| US12091701B2 (en) | 2016-03-29 | 2024-09-17 | Karydo Therapeutix, Inc. | Screening method for candidate substances for active component to prevent or treat at least one disease selected from the group consisting of renal hypofunction, chronic kidney disease and kidney failure |
| CN109641954A (zh) * | 2016-08-29 | 2019-04-16 | 里珍纳龙药品有限公司 | 抗-gremlin-1(grem1)抗体及其用于治疗肺动脉高血压的使用方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3309555A3 (en) | 2018-05-30 |
| EP2791684A2 (en) | 2014-10-22 |
| SG11201402996WA (en) | 2014-07-30 |
| AU2012350654C1 (en) | 2018-05-10 |
| JP2018118980A (ja) | 2018-08-02 |
| WO2013087654A2 (en) | 2013-06-20 |
| US9950034B2 (en) | 2018-04-24 |
| US9610356B2 (en) | 2017-04-04 |
| JP2015501822A (ja) | 2015-01-19 |
| AU2012350654A1 (en) | 2014-07-03 |
| US20180311311A1 (en) | 2018-11-01 |
| SG10201604574UA (en) | 2016-07-28 |
| WO2013087654A3 (en) | 2013-09-12 |
| EP3309555A2 (en) | 2018-04-18 |
| JP6305345B2 (ja) | 2018-04-04 |
| CA2858959A1 (en) | 2013-06-20 |
| US20140323389A1 (en) | 2014-10-30 |
| DK2791684T3 (da) | 2017-11-27 |
| US20170224770A1 (en) | 2017-08-10 |
| EP2791684B1 (en) | 2017-08-23 |
| AU2012350654B2 (en) | 2017-12-14 |
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Application publication date: 20140820 |