JP6300727B2 - コバインダー補助アッセイ法 - Google Patents
コバインダー補助アッセイ法 Download PDFInfo
- Publication number
- JP6300727B2 JP6300727B2 JP2014541281A JP2014541281A JP6300727B2 JP 6300727 B2 JP6300727 B2 JP 6300727B2 JP 2014541281 A JP2014541281 A JP 2014541281A JP 2014541281 A JP2014541281 A JP 2014541281A JP 6300727 B2 JP6300727 B2 JP 6300727B2
- Authority
- JP
- Japan
- Prior art keywords
- binding
- oligonucleotide sequence
- analyte
- oligonucleotide
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161558537P | 2011-11-11 | 2011-11-11 | |
US61/558,537 | 2011-11-11 | ||
PCT/US2012/064263 WO2013070990A1 (en) | 2011-11-11 | 2012-11-09 | Co-binder assisted assay methods |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2017231321A Division JP6795733B2 (ja) | 2011-11-11 | 2017-12-01 | コバインダー補助アッセイ法 |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2014533364A JP2014533364A (ja) | 2014-12-11 |
JP2014533364A5 JP2014533364A5 (enrdf_load_stackoverflow) | 2015-12-17 |
JP6300727B2 true JP6300727B2 (ja) | 2018-03-28 |
Family
ID=48290570
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014541281A Active JP6300727B2 (ja) | 2011-11-11 | 2012-11-09 | コバインダー補助アッセイ法 |
JP2017231321A Active JP6795733B2 (ja) | 2011-11-11 | 2017-12-01 | コバインダー補助アッセイ法 |
JP2020079957A Pending JP2020126068A (ja) | 2011-11-11 | 2020-04-30 | コバインダー補助アッセイ法 |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2017231321A Active JP6795733B2 (ja) | 2011-11-11 | 2017-12-01 | コバインダー補助アッセイ法 |
JP2020079957A Pending JP2020126068A (ja) | 2011-11-11 | 2020-04-30 | コバインダー補助アッセイ法 |
Country Status (6)
Country | Link |
---|---|
US (3) | US9777338B2 (enrdf_load_stackoverflow) |
EP (2) | EP3467500B1 (enrdf_load_stackoverflow) |
JP (3) | JP6300727B2 (enrdf_load_stackoverflow) |
DK (2) | DK3467500T3 (enrdf_load_stackoverflow) |
ES (2) | ES2700792T3 (enrdf_load_stackoverflow) |
WO (1) | WO2013070990A1 (enrdf_load_stackoverflow) |
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US10114015B2 (en) | 2013-03-13 | 2018-10-30 | Meso Scale Technologies, Llc. | Assay methods |
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KR102757668B1 (ko) | 2014-05-15 | 2025-01-21 | 메소 스케일 테크놀러지즈, 엘엘시 | 개선된 분석 방법 |
ES2836802T3 (es) | 2015-02-27 | 2021-06-28 | Becton Dickinson Co | Códigos de barras moleculares espacialmente direccionables |
ES2934982T3 (es) | 2015-03-30 | 2023-02-28 | Becton Dickinson Co | Métodos para la codificación con códigos de barras combinatorios |
WO2016172373A1 (en) | 2015-04-23 | 2016-10-27 | Cellular Research, Inc. | Methods and compositions for whole transcriptome amplification |
WO2017044574A1 (en) | 2015-09-11 | 2017-03-16 | Cellular Research, Inc. | Methods and compositions for nucleic acid library normalization |
EP3356547B1 (en) | 2015-10-01 | 2020-11-18 | Dynamic Biosensors GmbH | Method for detecting molecular interactions using an immobilized nucleic acid |
CA3017945A1 (en) * | 2016-04-26 | 2017-11-02 | Ultivue, Inc. | Super-resolution immunofluorescence with diffraction-limited preview |
US10301677B2 (en) | 2016-05-25 | 2019-05-28 | Cellular Research, Inc. | Normalization of nucleic acid libraries |
US10640763B2 (en) | 2016-05-31 | 2020-05-05 | Cellular Research, Inc. | Molecular indexing of internal sequences |
US10202641B2 (en) | 2016-05-31 | 2019-02-12 | Cellular Research, Inc. | Error correction in amplification of samples |
CN110073212B (zh) | 2016-09-16 | 2024-03-01 | 博铼生技股份有限公司 | 用于多重测试的方法和系统 |
BR112019005900A2 (pt) | 2016-09-26 | 2019-06-11 | Becton Dickinson Co | medição de expressão de proteínas usando reagentes com sequências de oligonucleotídeos com código de barras |
EP3577232A1 (en) | 2017-02-01 | 2019-12-11 | Cellular Research, Inc. | Selective amplification using blocking oligonucleotides |
CN110719959B (zh) | 2017-06-05 | 2021-08-06 | 贝克顿迪金森公司 | 针对单细胞的样品索引 |
EP4545647A3 (en) | 2018-05-03 | 2025-07-09 | Becton, Dickinson and Company | Molecular barcoding on opposite transcript ends |
EP3788171B1 (en) | 2018-05-03 | 2023-04-05 | Becton, Dickinson and Company | High throughput multiomics sample analysis |
WO2020072380A1 (en) | 2018-10-01 | 2020-04-09 | Cellular Research, Inc. | Determining 5' transcript sequences |
EP3877520B1 (en) | 2018-11-08 | 2025-03-19 | Becton, Dickson And Company | Whole transcriptome analysis of single cells using random priming |
EP3894552A1 (en) | 2018-12-13 | 2021-10-20 | Becton, Dickinson and Company | Selective extension in single cell whole transcriptome analysis |
CN113574178B (zh) | 2019-01-23 | 2024-10-29 | 贝克顿迪金森公司 | 与抗体关联的寡核苷酸 |
WO2020167920A1 (en) | 2019-02-14 | 2020-08-20 | Cellular Research, Inc. | Hybrid targeted and whole transcriptome amplification |
WO2020214642A1 (en) | 2019-04-19 | 2020-10-22 | Becton, Dickinson And Company | Methods of associating phenotypical data and single cell sequencing data |
US11939622B2 (en) | 2019-07-22 | 2024-03-26 | Becton, Dickinson And Company | Single cell chromatin immunoprecipitation sequencing assay |
ES2987640T3 (es) | 2019-11-08 | 2024-11-15 | Becton Dickinson Co | Uso de cebado aleatorio para obtener información de V(D)J de longitud completa para la secuenciación del repertorio inmunitario |
EP4090763B1 (en) | 2020-01-13 | 2024-12-04 | Becton Dickinson and Company | Methods and compositions for quantitation of proteins and rna |
CN115335520A (zh) | 2020-01-29 | 2022-11-11 | 贝克顿迪金森公司 | 用于通过测序对单细胞进行空间映射的条形码化的孔 |
CN115151810A (zh) | 2020-02-25 | 2022-10-04 | 贝克顿迪金森公司 | 实现使用单细胞样品作为单色补偿对照的双特异性探针 |
EP4150118A1 (en) | 2020-05-14 | 2023-03-22 | Becton Dickinson and Company | Primers for immune repertoire profiling |
EP4158055B1 (en) | 2020-06-02 | 2024-03-27 | Becton, Dickinson and Company | Oligonucleotides and beads for 5 prime gene expression assay |
US11932901B2 (en) | 2020-07-13 | 2024-03-19 | Becton, Dickinson And Company | Target enrichment using nucleic acid probes for scRNAseq |
WO2022018622A1 (en) | 2020-07-20 | 2022-01-27 | United Arab Emirates University | Method and system for virus and protein-antibody interactions detection and monitoring based on optical light intensity and electrical parameters |
US11619589B2 (en) | 2020-07-20 | 2023-04-04 | United Arab Emirates University | Method and system for detection, quantification and/or identification of an analyte in a specimen based on electrical and/or optical response to an electric field |
US12391940B2 (en) | 2020-07-31 | 2025-08-19 | Becton, Dickinson And Company | Single cell assay for transposase-accessible chromatin |
US11739443B2 (en) | 2020-11-20 | 2023-08-29 | Becton, Dickinson And Company | Profiling of highly expressed and lowly expressed proteins |
EP4263859A1 (en) | 2020-12-15 | 2023-10-25 | Becton, Dickinson and Company | Single cell secretome analysis |
WO2023080137A1 (ja) * | 2021-11-04 | 2023-05-11 | 凸版印刷株式会社 | 標的物質の検出方法 |
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2012
- 2012-11-09 DK DK18192525.6T patent/DK3467500T3/da active
- 2012-11-09 EP EP18192525.6A patent/EP3467500B1/en active Active
- 2012-11-09 US US14/357,653 patent/US9777338B2/en active Active
- 2012-11-09 DK DK12848432.6T patent/DK2776833T3/da active
- 2012-11-09 WO PCT/US2012/064263 patent/WO2013070990A1/en active Application Filing
- 2012-11-09 ES ES12848432T patent/ES2700792T3/es active Active
- 2012-11-09 ES ES18192525T patent/ES2884100T3/es active Active
- 2012-11-09 EP EP12848432.6A patent/EP2776833B1/en active Active
- 2012-11-09 JP JP2014541281A patent/JP6300727B2/ja active Active
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2017
- 2017-09-06 US US15/696,953 patent/US11242570B2/en active Active
- 2017-12-01 JP JP2017231321A patent/JP6795733B2/ja active Active
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2020
- 2020-04-30 JP JP2020079957A patent/JP2020126068A/ja active Pending
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2021
- 2021-10-19 US US17/504,937 patent/US12359264B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US12359264B2 (en) | 2025-07-15 |
ES2884100T3 (es) | 2021-12-10 |
EP2776833B1 (en) | 2018-09-05 |
EP3467500A1 (en) | 2019-04-10 |
EP2776833A1 (en) | 2014-09-17 |
JP6795733B2 (ja) | 2020-12-02 |
JP2020126068A (ja) | 2020-08-20 |
JP2014533364A (ja) | 2014-12-11 |
JP2018054629A (ja) | 2018-04-05 |
DK3467500T3 (da) | 2021-08-16 |
US9777338B2 (en) | 2017-10-03 |
WO2013070990A1 (en) | 2013-05-16 |
US20170362668A1 (en) | 2017-12-21 |
EP3467500B1 (en) | 2021-05-12 |
DK2776833T3 (da) | 2019-01-02 |
US11242570B2 (en) | 2022-02-08 |
US20140315189A1 (en) | 2014-10-23 |
US20220033918A1 (en) | 2022-02-03 |
ES2700792T3 (es) | 2019-02-19 |
EP2776833A4 (en) | 2015-12-02 |
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