JP6299750B2 - 生体物質捕獲用のフィルター - Google Patents
生体物質捕獲用のフィルター Download PDFInfo
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- JP6299750B2 JP6299750B2 JP2015509958A JP2015509958A JP6299750B2 JP 6299750 B2 JP6299750 B2 JP 6299750B2 JP 2015509958 A JP2015509958 A JP 2015509958A JP 2015509958 A JP2015509958 A JP 2015509958A JP 6299750 B2 JP6299750 B2 JP 6299750B2
- Authority
- JP
- Japan
- Prior art keywords
- biological material
- gold
- filter
- plating
- gold plating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- 239000012620 biological material Substances 0.000 title claims description 27
- 238000007747 plating Methods 0.000 claims description 140
- 239000010931 gold Substances 0.000 claims description 120
- 229910052737 gold Inorganic materials 0.000 claims description 109
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 107
- 229910052751 metal Inorganic materials 0.000 claims description 45
- 239000002184 metal Substances 0.000 claims description 45
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 claims description 43
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 28
- 239000010949 copper Substances 0.000 claims description 21
- 206010028980 Neoplasm Diseases 0.000 claims description 18
- 201000011510 cancer Diseases 0.000 claims description 18
- 229910052802 copper Inorganic materials 0.000 claims description 18
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 claims description 15
- 238000006073 displacement reaction Methods 0.000 claims description 14
- 229910052759 nickel Inorganic materials 0.000 claims description 11
- 229910052709 silver Inorganic materials 0.000 claims description 10
- SRCZENKQCOSNAI-UHFFFAOYSA-H gold(3+);trisulfite Chemical compound [Au+3].[Au+3].[O-]S([O-])=O.[O-]S([O-])=O.[O-]S([O-])=O SRCZENKQCOSNAI-UHFFFAOYSA-H 0.000 claims description 8
- 239000004332 silver Substances 0.000 claims description 8
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims description 7
- 229910052763 palladium Inorganic materials 0.000 claims description 7
- 239000000956 alloy Substances 0.000 claims description 3
- 229910045601 alloy Inorganic materials 0.000 claims description 3
- QUCZBHXJAUTYHE-UHFFFAOYSA-N gold Chemical compound [Au].[Au] QUCZBHXJAUTYHE-UHFFFAOYSA-N 0.000 claims 1
- 239000000243 solution Substances 0.000 description 55
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 30
- 210000004027 cell Anatomy 0.000 description 28
- 229920002120 photoresistant polymer Polymers 0.000 description 22
- 239000000126 substance Substances 0.000 description 20
- -1 for example Substances 0.000 description 17
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- 239000000758 substrate Substances 0.000 description 14
- 229920000249 biocompatible polymer Polymers 0.000 description 13
- 210000005266 circulating tumour cell Anatomy 0.000 description 13
- 230000000694 effects Effects 0.000 description 13
- 238000010828 elution Methods 0.000 description 13
- 229910021645 metal ion Inorganic materials 0.000 description 13
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 12
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 12
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 12
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- 229940071106 ethylenediaminetetraacetate Drugs 0.000 description 11
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- 150000001875 compounds Chemical class 0.000 description 10
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- 150000002500 ions Chemical class 0.000 description 9
- 238000006467 substitution reaction Methods 0.000 description 9
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 8
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- 239000011651 chromium Substances 0.000 description 6
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- 150000003464 sulfur compounds Chemical class 0.000 description 6
- CWERGRDVMFNCDR-UHFFFAOYSA-N thioglycolic acid Chemical compound OC(=O)CS CWERGRDVMFNCDR-UHFFFAOYSA-N 0.000 description 6
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 5
- 239000003513 alkali Substances 0.000 description 5
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- 230000000052 comparative effect Effects 0.000 description 5
- UFULAYFCSOUIOV-UHFFFAOYSA-N cysteamine Chemical compound NCCS UFULAYFCSOUIOV-UHFFFAOYSA-N 0.000 description 5
- 238000011161 development Methods 0.000 description 5
- 229910001385 heavy metal Inorganic materials 0.000 description 5
- 229910010272 inorganic material Inorganic materials 0.000 description 5
- XEEYBQQBJWHFJM-UHFFFAOYSA-N iron Substances [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 5
- 150000002739 metals Chemical class 0.000 description 5
- 239000006179 pH buffering agent Substances 0.000 description 5
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Substances [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 5
- 239000011347 resin Substances 0.000 description 5
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- 238000004381 surface treatment Methods 0.000 description 5
- 108091003079 Bovine Serum Albumin Proteins 0.000 description 4
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 4
- 125000003277 amino group Chemical group 0.000 description 4
- 150000003863 ammonium salts Chemical class 0.000 description 4
- RQNWIZPPADIBDY-UHFFFAOYSA-N arsenic atom Chemical class [As] RQNWIZPPADIBDY-UHFFFAOYSA-N 0.000 description 4
- 231100000135 cytotoxicity Toxicity 0.000 description 4
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- 238000003475 lamination Methods 0.000 description 4
- 229910000510 noble metal Inorganic materials 0.000 description 4
- 238000012545 processing Methods 0.000 description 4
- 239000011342 resin composition Substances 0.000 description 4
- PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 description 4
- SDKPSXWGRWWLKR-UHFFFAOYSA-M sodium;9,10-dioxoanthracene-1-sulfonate Chemical compound [Na+].O=C1C2=CC=CC=C2C(=O)C2=C1C=CC=C2S(=O)(=O)[O-] SDKPSXWGRWWLKR-UHFFFAOYSA-M 0.000 description 4
- 239000010409 thin film Substances 0.000 description 4
- 239000011135 tin Substances 0.000 description 4
- 238000005406 washing Methods 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- LSDPWZHWYPCBBB-UHFFFAOYSA-N Methanethiol Chemical class SC LSDPWZHWYPCBBB-UHFFFAOYSA-N 0.000 description 3
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 description 3
- LSNNMFCWUKXFEE-UHFFFAOYSA-N Sulfurous acid Chemical compound OS(O)=O LSNNMFCWUKXFEE-UHFFFAOYSA-N 0.000 description 3
- 102000004142 Trypsin Human genes 0.000 description 3
- 108090000631 Trypsin Proteins 0.000 description 3
- UMGDCJDMYOKAJW-UHFFFAOYSA-N aminothiocarboxamide Natural products NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 description 3
- QZPSXPBJTPJTSZ-UHFFFAOYSA-N aqua regia Chemical compound Cl.O[N+]([O-])=O QZPSXPBJTPJTSZ-UHFFFAOYSA-N 0.000 description 3
- 239000010953 base metal Substances 0.000 description 3
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 description 3
- 239000004327 boric acid Substances 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- 231100000433 cytotoxic Toxicity 0.000 description 3
- 230000001472 cytotoxic effect Effects 0.000 description 3
- 125000002228 disulfide group Chemical group 0.000 description 3
- 239000010419 fine particle Substances 0.000 description 3
- 239000011888 foil Substances 0.000 description 3
- 239000011521 glass Substances 0.000 description 3
- 229910052739 hydrogen Inorganic materials 0.000 description 3
- 239000001257 hydrogen Substances 0.000 description 3
- 229910052741 iridium Inorganic materials 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 229910052757 nitrogen Inorganic materials 0.000 description 3
- 239000003002 pH adjusting agent Substances 0.000 description 3
- 229920000642 polymer Polymers 0.000 description 3
- 238000001953 recrystallisation Methods 0.000 description 3
- 125000000101 thioether group Chemical group 0.000 description 3
- 150000003568 thioethers Chemical class 0.000 description 3
- 125000003396 thiol group Chemical group [H]S* 0.000 description 3
- RMVRSNDYEFQCLF-UHFFFAOYSA-N thiophenol Chemical compound SC1=CC=CC=C1 RMVRSNDYEFQCLF-UHFFFAOYSA-N 0.000 description 3
- 230000001988 toxicity Effects 0.000 description 3
- 231100000419 toxicity Toxicity 0.000 description 3
- 239000012588 trypsin Substances 0.000 description 3
- FNQJDLTXOVEEFB-UHFFFAOYSA-N 1,2,3-benzothiadiazole Chemical compound C1=CC=C2SN=NC2=C1 FNQJDLTXOVEEFB-UHFFFAOYSA-N 0.000 description 2
- YXIWHUQXZSMYRE-UHFFFAOYSA-N 1,3-benzothiazole-2-thiol Chemical compound C1=CC=C2SC(S)=NC2=C1 YXIWHUQXZSMYRE-UHFFFAOYSA-N 0.000 description 2
- FCEHBMOGCRZNNI-UHFFFAOYSA-N 1-benzothiophene Chemical compound C1=CC=C2SC=CC2=C1 FCEHBMOGCRZNNI-UHFFFAOYSA-N 0.000 description 2
- PRDFBSVERLRRMY-UHFFFAOYSA-N 2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-2,5'-bibenzimidazole Chemical compound C1=CC(OCC)=CC=C1C1=NC2=CC=C(C=3NC4=CC(=CC=C4N=3)N3CCN(C)CC3)C=C2N1 PRDFBSVERLRRMY-UHFFFAOYSA-N 0.000 description 2
- WQNHWIYLCRZRLR-UHFFFAOYSA-N 2-(3-hydroxy-2,5-dioxooxolan-3-yl)acetic acid Chemical compound OC(=O)CC1(O)CC(=O)OC1=O WQNHWIYLCRZRLR-UHFFFAOYSA-N 0.000 description 2
- CDAWCLOXVUBKRW-UHFFFAOYSA-N 2-aminophenol Chemical compound NC1=CC=CC=C1O CDAWCLOXVUBKRW-UHFFFAOYSA-N 0.000 description 2
- MLPVBIWIRCKMJV-UHFFFAOYSA-N 2-ethylaniline Chemical compound CCC1=CC=CC=C1N MLPVBIWIRCKMJV-UHFFFAOYSA-N 0.000 description 2
- NZUQQADVSXWVNW-UHFFFAOYSA-N 2-ethylsulfanylpropane Chemical compound CCSC(C)C NZUQQADVSXWVNW-UHFFFAOYSA-N 0.000 description 2
- YCLSOMLVSHPPFV-UHFFFAOYSA-N 3-(2-carboxyethyldisulfanyl)propanoic acid Chemical compound OC(=O)CCSSCCC(O)=O YCLSOMLVSHPPFV-UHFFFAOYSA-N 0.000 description 2
- WCDSVWRUXWCYFN-UHFFFAOYSA-N 4-aminobenzenethiol Chemical compound NC1=CC=C(S)C=C1 WCDSVWRUXWCYFN-UHFFFAOYSA-N 0.000 description 2
- PLIKAWJENQZMHA-UHFFFAOYSA-N 4-aminophenol Chemical compound NC1=CC=C(O)C=C1 PLIKAWJENQZMHA-UHFFFAOYSA-N 0.000 description 2
- HRXZRAXKKNUKRF-UHFFFAOYSA-N 4-ethylaniline Chemical compound CCC1=CC=C(N)C=C1 HRXZRAXKKNUKRF-UHFFFAOYSA-N 0.000 description 2
- HXDOZKJGKXYMEW-UHFFFAOYSA-N 4-ethylphenol Chemical compound CCC1=CC=C(O)C=C1 HXDOZKJGKXYMEW-UHFFFAOYSA-N 0.000 description 2
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 description 2
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- CETBSQOFQKLHHZ-UHFFFAOYSA-N Diethyl disulfide Chemical compound CCSSCC CETBSQOFQKLHHZ-UHFFFAOYSA-N 0.000 description 2
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 description 2
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- DLLMHEDYJQACRM-UHFFFAOYSA-N 2-(carboxymethyldisulfanyl)acetic acid Chemical compound OC(=O)CSSCC(O)=O DLLMHEDYJQACRM-UHFFFAOYSA-N 0.000 description 1
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- LESFYQKBUCDEQP-UHFFFAOYSA-N tetraazanium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound N.N.N.N.OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O LESFYQKBUCDEQP-UHFFFAOYSA-N 0.000 description 1
- JZBRFIUYUGTUGG-UHFFFAOYSA-J tetrapotassium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [K+].[K+].[K+].[K+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O JZBRFIUYUGTUGG-UHFFFAOYSA-J 0.000 description 1
- GBECUEIQVRDUKB-UHFFFAOYSA-M thallium monochloride Chemical class [Tl]Cl GBECUEIQVRDUKB-UHFFFAOYSA-M 0.000 description 1
- YTQVHRVITVLIRD-UHFFFAOYSA-L thallium sulfate Chemical class [Tl+].[Tl+].[O-]S([O-])(=O)=O YTQVHRVITVLIRD-UHFFFAOYSA-L 0.000 description 1
- UFVDXEXHBVQKGB-UHFFFAOYSA-L thallous malonate Chemical class [Tl+].[Tl+].[O-]C(=O)CC([O-])=O UFVDXEXHBVQKGB-UHFFFAOYSA-L 0.000 description 1
- 238000009210 therapy by ultrasound Methods 0.000 description 1
- 150000003557 thiazoles Chemical class 0.000 description 1
- 150000003567 thiocyanates Chemical class 0.000 description 1
- UVZICZIVKIMRNE-UHFFFAOYSA-N thiodiacetic acid Chemical compound OC(=O)CSCC(O)=O UVZICZIVKIMRNE-UHFFFAOYSA-N 0.000 description 1
- YODZTKMDCQEPHD-UHFFFAOYSA-N thiodiglycol Chemical compound OCCSCCO YODZTKMDCQEPHD-UHFFFAOYSA-N 0.000 description 1
- 229950006389 thiodiglycol Drugs 0.000 description 1
- 235000019303 thiodipropionic acid Nutrition 0.000 description 1
- NJRXVEJTAYWCQJ-UHFFFAOYSA-N thiomalic acid Chemical compound OC(=O)CC(S)C(O)=O NJRXVEJTAYWCQJ-UHFFFAOYSA-N 0.000 description 1
- 229930192474 thiophene Natural products 0.000 description 1
- NBOMNTLFRHMDEZ-UHFFFAOYSA-N thiosalicylic acid Chemical compound OC(=O)C1=CC=CC=C1S NBOMNTLFRHMDEZ-UHFFFAOYSA-N 0.000 description 1
- 229940103494 thiosalicylic acid Drugs 0.000 description 1
- 150000004764 thiosulfuric acid derivatives Chemical class 0.000 description 1
- 150000003585 thioureas Chemical class 0.000 description 1
- 229910052718 tin Inorganic materials 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- CENHPXAQKISCGD-UHFFFAOYSA-N trioxathietane 4,4-dioxide Chemical compound O=S1(=O)OOO1 CENHPXAQKISCGD-UHFFFAOYSA-N 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D39/00—Filtering material for liquid or gaseous fluids
- B01D39/10—Filter screens essentially made of metal
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2239/00—Aspects relating to filtering material for liquid or gaseous fluids
- B01D2239/04—Additives and treatments of the filtering material
- B01D2239/0471—Surface coating material
- B01D2239/0478—Surface coating material on a layer of the filter
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemically Coating (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- General Chemical & Material Sciences (AREA)
- Sustainable Development (AREA)
- Physics & Mathematics (AREA)
- Filtering Materials (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Metallurgy (AREA)
- Mechanical Engineering (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Thermal Sciences (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- Electroplating Methods And Accessories (AREA)
Applications Claiming Priority (3)
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|---|---|---|---|
| US201361808244P | 2013-04-04 | 2013-04-04 | |
| US61/808244 | 2013-04-04 | ||
| PCT/JP2014/055439 WO2014162810A1 (ja) | 2013-04-04 | 2014-03-04 | 生体物質捕獲用のフィルター |
Related Child Applications (1)
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| JP2018036325A Division JP6540842B2 (ja) | 2013-04-04 | 2018-03-01 | 生体物質捕獲用のフィルター |
Publications (2)
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| JPWO2014162810A1 JPWO2014162810A1 (ja) | 2017-02-16 |
| JP6299750B2 true JP6299750B2 (ja) | 2018-03-28 |
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| JP2015509958A Expired - Fee Related JP6299750B2 (ja) | 2013-04-04 | 2014-03-04 | 生体物質捕獲用のフィルター |
| JP2018036325A Expired - Fee Related JP6540842B2 (ja) | 2013-04-04 | 2018-03-01 | 生体物質捕獲用のフィルター |
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| JP2018036325A Expired - Fee Related JP6540842B2 (ja) | 2013-04-04 | 2018-03-01 | 生体物質捕獲用のフィルター |
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| Country | Link |
|---|---|
| US (2) | US20140299539A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2982743B1 (cg-RX-API-DMAC7.html) |
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| CN (1) | CN105102606A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2014162810A1 (cg-RX-API-DMAC7.html) |
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| US10022659B2 (en) * | 2013-07-24 | 2018-07-17 | Aichi Prefecture | Device for isolating periphery circulating tumor cells or rare cells, and method of isolating periphery circulating tumor cells or rare cells |
| WO2016035772A1 (ja) * | 2014-09-03 | 2016-03-10 | 日立化成株式会社 | 生体物質捕獲用フィルター及び生体物質捕獲システム |
| JP2016086736A (ja) * | 2014-11-05 | 2016-05-23 | 日立化成株式会社 | 血中希少細胞含有液の製造方法 |
| US10577704B2 (en) * | 2015-06-26 | 2020-03-03 | Metalor Technologies Corporation | Electrolytic hard gold plating solution substitution inhibitor and electrolytic hard gold plating solution including same |
| TW201732033A (zh) * | 2016-02-01 | 2017-09-16 | 日立化成股份有限公司 | 細胞捕捉過濾器、細胞捕捉裝置、細胞捕捉方法、細胞觀察方法及細胞培養方法 |
| JP6779483B2 (ja) | 2016-09-29 | 2020-11-04 | 住友ゴム工業株式会社 | 医療用検査装置及び細胞検査方法 |
| WO2018163757A1 (ja) * | 2017-03-10 | 2018-09-13 | 株式会社村田製作所 | 細胞濾過フィルタ |
| CN109414657B (zh) * | 2017-03-21 | 2022-01-04 | 株式会社村田制作所 | 细胞捕捉用过滤器及劣化判定方法、细胞捕捉用过滤器组 |
| US20180335434A1 (en) * | 2017-05-17 | 2018-11-22 | Hitachi Chemical Company, Ltd. | Methods of Detecting Circulating Tumor Cells |
| WO2018220835A1 (ja) * | 2017-06-02 | 2018-12-06 | 日立化成株式会社 | 血液試料中の希少細胞を分離する方法及び該細胞の遺伝子を解析する方法 |
| JP7158671B2 (ja) * | 2018-02-14 | 2022-10-24 | 住友ゴム工業株式会社 | 特定細胞捕捉方法 |
| JP7109719B2 (ja) | 2018-02-14 | 2022-08-01 | 住友ゴム工業株式会社 | 特定細胞捕捉方法 |
| WO2019181158A1 (ja) * | 2018-03-19 | 2019-09-26 | 株式会社村田製作所 | 濾過フィルタ及び濾過装置 |
| WO2020145096A1 (ja) * | 2019-01-07 | 2020-07-16 | 株式会社村田製作所 | 濾過フィルタ |
| US11614440B2 (en) | 2019-01-24 | 2023-03-28 | Sumitomo Rubber Industries, Ltd. | Specific cell fractionating and capturing methods |
| CN110054142A (zh) * | 2019-04-29 | 2019-07-26 | 太原理工大学 | 一种基于mems技术的空气过滤薄膜及其制备方法 |
| JP7400963B2 (ja) * | 2020-05-18 | 2023-12-19 | 株式会社村田製作所 | フィルタ |
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| US5061621A (en) * | 1989-06-22 | 1991-10-29 | Brandeis University | Replica plating device with an integral marking element |
| US5629213A (en) * | 1995-03-03 | 1997-05-13 | Kornguth; Steven E. | Analytical biosensor |
| US20020119579A1 (en) * | 1998-07-14 | 2002-08-29 | Peter Wagner | Arrays devices and methods of use thereof |
| US6277489B1 (en) * | 1998-12-04 | 2001-08-21 | The Regents Of The University Of California | Support for high performance affinity chromatography and other uses |
| US6733823B2 (en) * | 2001-04-03 | 2004-05-11 | The Johns Hopkins University | Method for electroless gold plating of conductive traces on printed circuit boards |
| US20050003459A1 (en) * | 2002-01-30 | 2005-01-06 | Krutzik Siegfried Richard | Multi-purpose optical analysis disc for conducting assays and related methods for attaching capture agents |
| US8101243B2 (en) * | 2002-04-03 | 2012-01-24 | Colorado School Of Mines | Method of making sulfur-resistant composite metal membranes |
| JP2004176171A (ja) * | 2002-09-30 | 2004-06-24 | Shinko Electric Ind Co Ltd | 非シアン電解金めっき液 |
| GB0420062D0 (en) * | 2004-09-09 | 2004-10-13 | Akubio Ltd | Assay methods,materials and preparations |
| JP5416330B2 (ja) * | 2005-03-10 | 2014-02-12 | 日本高純度化学株式会社 | 金めっき液用亜硫酸金塩水溶液の製造方法 |
| JP4759416B2 (ja) * | 2006-03-20 | 2011-08-31 | 新光電気工業株式会社 | 非シアン無電解金めっき液及び無電解金めっき方法 |
| WO2008130445A2 (en) * | 2006-11-10 | 2008-10-30 | Advanced Analytical Technologies, Inc. | Rapid detection microorganisms in fluids |
| JP2008240083A (ja) * | 2007-03-28 | 2008-10-09 | Ne Chemcat Corp | 無電解金めっき液 |
| JP5135617B2 (ja) * | 2008-01-30 | 2013-02-06 | 三菱電機株式会社 | 無電解めっき方法 |
| WO2010135603A2 (en) | 2009-05-20 | 2010-11-25 | California Institute Of Technology | Method for cancer detection, diagnosis and prognosis |
| US20110042299A1 (en) * | 2009-08-20 | 2011-02-24 | General Electric Company | Composite membrane assemblies and methods of making and using the same |
| WO2012151501A2 (en) * | 2011-05-05 | 2012-11-08 | Anpac Bio-Medical Science Co., Ltd. | Apparatus for detecting tumor cells |
| CN103635801A (zh) * | 2011-06-13 | 2014-03-12 | 日立化成株式会社 | 癌细胞粘附性提高剂 |
| JP5854456B2 (ja) | 2011-08-23 | 2016-02-09 | 日立化成株式会社 | 癌細胞濃縮フィルター |
| EP2851418A4 (en) * | 2012-05-14 | 2015-12-23 | Hitachi Chemical Co Ltd | CANCER-DETECTED METAL FILTER, FILM WITH THE CANCER-MEASURING METAL FILTER, CANCER CELL DETECTION DEVICE AND MANUFACTURING METHOD THEREFOR |
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2014
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- 2014-03-04 WO PCT/JP2014/055439 patent/WO2014162810A1/ja not_active Ceased
- 2014-03-04 JP JP2015509958A patent/JP6299750B2/ja not_active Expired - Fee Related
- 2014-03-04 KR KR1020157031035A patent/KR20150138298A/ko not_active Withdrawn
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2018
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Also Published As
| Publication number | Publication date |
|---|---|
| KR20150138298A (ko) | 2015-12-09 |
| EP2982743B1 (en) | 2019-07-17 |
| US20180021708A1 (en) | 2018-01-25 |
| JP2018088932A (ja) | 2018-06-14 |
| JPWO2014162810A1 (ja) | 2017-02-16 |
| US20140299539A1 (en) | 2014-10-09 |
| JP6540842B2 (ja) | 2019-07-10 |
| EP2982743A1 (en) | 2016-02-10 |
| CN105102606A (zh) | 2015-11-25 |
| EP2982743A4 (en) | 2016-11-30 |
| WO2014162810A1 (ja) | 2014-10-09 |
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