JP6284942B2 - ４−アミノ−２，５−ジメトキシピリミジンから２−アミノ−５，８−ジメトキシ［１，２，４］トリアゾロ［１，５−ｃ］ピリミジンを調製するための改善された方法 - Google Patents
４−アミノ−２，５−ジメトキシピリミジンから２−アミノ−５，８−ジメトキシ［１，２，４］トリアゾロ［１，５−ｃ］ピリミジンを調製するための改善された方法 Download PDFInfo
- Publication number
- JP6284942B2 JP6284942B2 JP2015532005A JP2015532005A JP6284942B2 JP 6284942 B2 JP6284942 B2 JP 6284942B2 JP 2015532005 A JP2015532005 A JP 2015532005A JP 2015532005 A JP2015532005 A JP 2015532005A JP 6284942 B2 JP6284942 B2 JP 6284942B2
- Authority
- JP
- Japan
- Prior art keywords
- amino
- triazolo
- pyrimidine
- temperature
- aprotic solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261701242P | 2012-09-14 | 2012-09-14 | |
| US61/701,242 | 2012-09-14 | ||
| PCT/US2013/059108 WO2014043148A1 (en) | 2012-09-14 | 2013-09-11 | An improved process for the preparation of 2-amino-5,8-dimethoxy[1,2,4]triazolo[1,5-c]pyrimidine from 4-amino-2,5-dimethoxypyrimidine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015528497A JP2015528497A (ja) | 2015-09-28 |
| JP6284942B2 true JP6284942B2 (ja) | 2018-02-28 |
Family
ID=50275134
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015532005A Active JP6284942B2 (ja) | 2012-09-14 | 2013-09-11 | ４−アミノ−２，５−ジメトキシピリミジンから２−アミノ−５，８−ジメトキシ［１，２，４］トリアゾロ［１，５−ｃ］ピリミジンを調製するための改善された方法 |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US9115135B2 (enExample) |
| EP (1) | EP2895487B1 (enExample) |
| JP (1) | JP6284942B2 (enExample) |
| KR (1) | KR102120190B1 (enExample) |
| CN (1) | CN104768954B (enExample) |
| AR (1) | AR094442A1 (enExample) |
| AU (1) | AU2013315643B2 (enExample) |
| BR (1) | BR102013023418B1 (enExample) |
| CA (1) | CA2884110A1 (enExample) |
| HK (1) | HK1207064A1 (enExample) |
| IL (1) | IL237678A (enExample) |
| IN (1) | IN2015DN01969A (enExample) |
| MX (1) | MX2015003308A (enExample) |
| NZ (1) | NZ705677A (enExample) |
| PL (1) | PL2895487T3 (enExample) |
| RU (1) | RU2646603C2 (enExample) |
| TW (1) | TWI617562B (enExample) |
| UY (1) | UY35031A (enExample) |
| WO (1) | WO2014043148A1 (enExample) |
| ZA (1) | ZA201501733B (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10295147B2 (en) | 2006-11-09 | 2019-05-21 | Cree, Inc. | LED array and method for fabricating same |
| US10842016B2 (en) | 2011-07-06 | 2020-11-17 | Cree, Inc. | Compact optically efficient solid state light source with integrated thermal management |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6693116B2 (en) * | 2001-10-08 | 2004-02-17 | Hoffmann-La Roche Inc. | Adenosine receptor ligands |
| ATE382622T1 (de) * | 2003-12-23 | 2008-01-15 | Dow Agrosciences Llc | Verfahren zur herstellung von triazolopyrimidinen |
| TWI453207B (zh) * | 2008-09-08 | 2014-09-21 | Signal Pharm Llc | 胺基三唑并吡啶，其組合物及使用其之治療方法 |
| PL2576558T3 (pl) * | 2010-05-25 | 2015-05-29 | Dow Agrosciences Llc | Sposób wytwarzania 5-podstawionych 8-alkoksy[1,2,4]triazolo-[1,5-c]pirymidyno-2-amin |
-
2013
- 2013-09-11 AU AU2013315643A patent/AU2013315643B2/en active Active
- 2013-09-11 JP JP2015532005A patent/JP6284942B2/ja active Active
- 2013-09-11 MX MX2015003308A patent/MX2015003308A/es unknown
- 2013-09-11 NZ NZ705677A patent/NZ705677A/en not_active IP Right Cessation
- 2013-09-11 CN CN201380058735.3A patent/CN104768954B/zh active Active
- 2013-09-11 IN IN1969DEN2015 patent/IN2015DN01969A/en unknown
- 2013-09-11 PL PL13837313T patent/PL2895487T3/pl unknown
- 2013-09-11 CA CA2884110A patent/CA2884110A1/en not_active Abandoned
- 2013-09-11 RU RU2015113568A patent/RU2646603C2/ru active
- 2013-09-11 HK HK15107595.7A patent/HK1207064A1/xx unknown
- 2013-09-11 EP EP13837313.9A patent/EP2895487B1/en active Active
- 2013-09-11 WO PCT/US2013/059108 patent/WO2014043148A1/en not_active Ceased
- 2013-09-11 KR KR1020157009141A patent/KR102120190B1/ko active Active
- 2013-09-11 US US14/023,498 patent/US9115135B2/en active Active
- 2013-09-12 BR BR102013023418-4A patent/BR102013023418B1/pt active IP Right Grant
- 2013-09-13 AR ARP130103288A patent/AR094442A1/es active IP Right Grant
- 2013-09-13 TW TW102133203A patent/TWI617562B/zh not_active IP Right Cessation
- 2013-09-13 UY UY0001035031A patent/UY35031A/es not_active Application Discontinuation
-
2015
- 2015-03-11 IL IL237678A patent/IL237678A/en active IP Right Grant
- 2015-03-13 ZA ZA2015/01733A patent/ZA201501733B/en unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10295147B2 (en) | 2006-11-09 | 2019-05-21 | Cree, Inc. | LED array and method for fabricating same |
| US10842016B2 (en) | 2011-07-06 | 2020-11-17 | Cree, Inc. | Compact optically efficient solid state light source with integrated thermal management |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104768954A (zh) | 2015-07-08 |
| IN2015DN01969A (enExample) | 2015-08-14 |
| WO2014043148A1 (en) | 2014-03-20 |
| ZA201501733B (en) | 2016-10-26 |
| US9115135B2 (en) | 2015-08-25 |
| RU2646603C2 (ru) | 2018-03-06 |
| EP2895487B1 (en) | 2018-08-15 |
| KR102120190B1 (ko) | 2020-06-08 |
| IL237678A (en) | 2016-05-31 |
| TW201414738A (zh) | 2014-04-16 |
| TWI617562B (zh) | 2018-03-11 |
| KR20150056589A (ko) | 2015-05-26 |
| PL2895487T3 (pl) | 2019-02-28 |
| CN104768954B (zh) | 2017-11-17 |
| CA2884110A1 (en) | 2014-03-20 |
| MX2015003308A (es) | 2016-02-22 |
| BR102013023418A2 (pt) | 2014-11-11 |
| AU2013315643A1 (en) | 2015-03-26 |
| UY35031A (es) | 2014-04-30 |
| AU2013315643B2 (en) | 2016-11-17 |
| BR102013023418B1 (pt) | 2019-06-25 |
| HK1207064A1 (en) | 2016-01-22 |
| JP2015528497A (ja) | 2015-09-28 |
| RU2015113568A (ru) | 2016-11-10 |
| EP2895487A4 (en) | 2016-02-24 |
| NZ705677A (en) | 2018-01-26 |
| AR094442A1 (es) | 2015-08-05 |
| EP2895487A1 (en) | 2015-07-22 |
| US20140081024A1 (en) | 2014-03-20 |
| IL237678A0 (en) | 2015-04-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6811717B2 (ja) | トピロキソスタット及びその中間体の調製のための方法 | |
| JPH11322721A (ja) | 環式４―オキソアミジンの製造方法 | |
| CN112272665B (zh) | 制备立他司特的方法 | |
| JP2010510253A5 (enExample) | ||
| JP2015528497A (ja) | ４−アミノ−２，５−ジメトキシピリミジンから２−アミノ−５，８−ジメトキシ［１，２，４］トリアゾロ［１，５−ｃ］ピリミジンを調製するための改善された方法 | |
| CN106316885B (zh) | 一种3-[5-(2-氟苯基)-1,2,4-噁二唑-3-基]苯甲酸的制备方法 | |
| JP4097291B2 (ja) | 置換バリンアミド誘導体の製造方法 | |
| JP6293758B2 (ja) | ４−クロロ−２，５−ジメトキシピリミジンから２−アミノ−５，８−ジメトキシ［１，２，４］トリアゾロ［１，５−ｃ］ピリミジンを調製するための方法 | |
| JP2831000B2 (ja) | （２−アミノベンゾイル）酢酸エステル誘導体 | |
| JPH072742A (ja) | ４−アミノ−３−メチル−Ｎ−エチル−Ｎ−（β−ヒドロキシエチル）アニリン硫酸塩の新規製造法 | |
| JP2002155058A (ja) | １位置換ヒダントイン類の製造方法 | |
| CN110452165B (zh) | 一种2-甲基吡啶-4-甲酸的制备方法 | |
| EP3305780A1 (en) | Method for the preparation of h-arg(mis)-oh | |
| JPS6126910B2 (enExample) | ||
| JPH10195075A (ja) | Ｚ−バラシクロビルの製造方法 | |
| JP2001247549A (ja) | １位置換ヒダントイン類の製造方法 | |
| JP2008069089A (ja) | ４−アミノ−２−メルカプト−５−ピリミジンカルバルデヒドの製法 | |
| JPH052672B2 (enExample) | ||
| EP3315490A1 (en) | Method for the preparation of h-arg(mis)-oh | |
| JP2001002657A (ja) | ２−アルキル−４−クロロ−５−ヒドロキシメチルイミダゾール誘導体の製造法 | |
| WO2014080413A1 (en) | A process for the preparation of acebrophylline | |
| JP2003096047A (ja) | ウレイド誘導体の製造方法及びバルビツール酸誘導体の製造方法 | |
| JP2001002656A (ja) | ２−アルキル−４−クロロ−５−ヒドロキシメチルイミダゾール誘導体の製造法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20160829 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20170615 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20170620 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20170919 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20171120 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20180123 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20180131 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 6284942 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| S533 | Written request for registration of change of name |
Free format text: JAPANESE INTERMEDIATE CODE: R313533 |
|
| R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |