JP6261340B2 - 造血成長因子模倣体の使用 - Google Patents

造血成長因子模倣体の使用 Download PDF

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JP6261340B2
JP6261340B2 JP2013540029A JP2013540029A JP6261340B2 JP 6261340 B2 JP6261340 B2 JP 6261340B2 JP 2013540029 A JP2013540029 A JP 2013540029A JP 2013540029 A JP2013540029 A JP 2013540029A JP 6261340 B2 JP6261340 B2 JP 6261340B2
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optionally substituted
group
alkyl
aryl
heteroaryl
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JP2014502266A (ja
JP2014502266A5 (OSRAM
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リード ピー． ビソネット
リード ピー． ビソネット
アンドリュー アール． ハドソン
アンドリュー アール． ハドソン
キース ビー． マーシュケ
キース ビー． マーシュケ
ディーパ ルンタ
ディーパ ルンタ
リン チー
リン チー
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リガンド ファーマシューティカルズ インコーポレイテッド
リガンド ファーマシューティカルズ インコーポレイテッド
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    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
    • C07C243/38—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to carbon atoms of six-membered aromatic rings
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    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C07D491/113—Spiro-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring

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