JP6259474B2 - リゾホスファチジルコリン又はその誘導体を含む脂質ナノ物質、及びその製造方法 - Google Patents
リゾホスファチジルコリン又はその誘導体を含む脂質ナノ物質、及びその製造方法 Download PDFInfo
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- JP6259474B2 JP6259474B2 JP2015562912A JP2015562912A JP6259474B2 JP 6259474 B2 JP6259474 B2 JP 6259474B2 JP 2015562912 A JP2015562912 A JP 2015562912A JP 2015562912 A JP2015562912 A JP 2015562912A JP 6259474 B2 JP6259474 B2 JP 6259474B2
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Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
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- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5123—Organic compounds, e.g. fats, sugars
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
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- Oncology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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KR1020130026030A KR101951933B1 (ko) | 2013-03-12 | 2013-03-12 | 라이소포스파티딜콜린 또는 이의 유도체를 포함하는 지질나노물질 및 이의 제조방법 |
KR10-2013-0026030 | 2013-03-12 | ||
PCT/KR2014/002004 WO2014142517A1 (ko) | 2013-03-12 | 2014-03-11 | 라이소포스파티딜콜린 또는 이의 유도체를 포함하는 지질나노물질 및 이의 제조방법 |
Publications (2)
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JP2016518313A JP2016518313A (ja) | 2016-06-23 |
JP6259474B2 true JP6259474B2 (ja) | 2018-01-10 |
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US (1) | US10265333B2 (zh) |
EP (1) | EP2974715B1 (zh) |
JP (1) | JP6259474B2 (zh) |
KR (1) | KR101951933B1 (zh) |
CN (1) | CN105246487A (zh) |
ES (1) | ES2690393T3 (zh) |
WO (1) | WO2014142517A1 (zh) |
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KR102251078B1 (ko) * | 2014-10-28 | 2021-05-12 | (주) 에이치엔에이파마켐 | 리조포스파티딜콜린과 클로린 e6의 결합체를 함유하는 여드름 치료용 리포좀 조성물 |
US11016085B2 (en) * | 2016-04-25 | 2021-05-25 | The Johns Hopkins University | ZNT8 assays for drug development and pharmaceutical compositions |
US11077173B2 (en) | 2017-03-13 | 2021-08-03 | Sdg, Inc. | Lipid-based nanoparticles and methods using same |
WO2018169954A1 (en) | 2017-03-13 | 2018-09-20 | Sdg, Inc. | Lipid-based nanoparticles with enhanced stability |
CN111316099A (zh) | 2017-07-12 | 2020-06-19 | 约翰霍普金斯大学 | 用于1型糖尿病诊断的基于脂蛋白体的znt8自身抗原 |
KR20210114409A (ko) * | 2018-12-11 | 2021-09-23 | 디스럽션 랩스 인코퍼레이티드 | 치료제 전달용 조성물과 이의 이용 및 제조 방법 |
EP3986418A1 (en) | 2019-06-20 | 2022-04-27 | Aker Biomarine Antarctic As | Parenteral lysophosphatidylcholine formulations such as lpc-dha, lpc-epa and their use in therapy |
NL2023407B1 (en) | 2019-06-28 | 2021-02-01 | Aker Biomarine Antarctic As | Parenteral lysophosphatidylcholine formulations |
KR102189490B1 (ko) | 2020-04-22 | 2020-12-11 | 주식회사 아리바이오 | 라이소포스파티딜콜린(lysophosphatidylcholine, LPC) 또는 그의 에테르 유도체-함유 지질나노물질의 바이러스 감염 질환 치료용 조성물 |
IL307508A (en) * | 2021-04-12 | 2023-12-01 | Corner Therapeutics Inc | Mammalian dendritic cell hyperactivators |
WO2023150758A1 (en) * | 2022-02-07 | 2023-08-10 | Corner Therapeutics, Inc. | Hyperactivating lipid nanoparticles |
WO2023150757A1 (en) * | 2022-02-07 | 2023-08-10 | Corner Therapeutics, Inc. | Immunogenic mrna delivery vehicles |
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GB2046092B (en) * | 1979-03-05 | 1983-11-02 | Toyama Chemical Co Ltd | Pharmaceutical composition containing a lysophospholid and a phospholipid |
JPS57145810A (en) * | 1982-02-01 | 1982-09-09 | Toyama Chem Co Ltd | Immunological activator containing lysophospholipid and preparation thereof |
EP0628256B1 (fr) * | 1993-06-11 | 1997-08-13 | Societe Des Produits Nestle S.A. | Composition permettant de stabiliser thermiquement les protéines et produit ainsi obtenu |
FR2836828A1 (fr) * | 2002-03-11 | 2003-09-12 | Bio Merieux | Utilisation de l-alpha-lysophosphatidylcholine pour obtenir la differenciation de monocytes en cellules dendritiques matures in vitro |
FR2836829B1 (fr) * | 2002-03-11 | 2005-11-25 | Bio Merieux | Utilisation de l-alpha-lysophosphatidylcholine pour obtenir la differenciation de monocytes en cellules dendritiques matures in vitro |
ES2536710T3 (es) * | 2002-03-25 | 2015-05-27 | Arimed Inc. | Nuevo uso terapéutico de LPC, ligandos agonistas específicos para el receptor G2A |
KR100842160B1 (ko) | 2002-10-21 | 2008-06-27 | 주식회사 바이오시너젠 | 라이소포스파티딜콜린 또는 그 유사체를 포함하는 패혈증예방 및 치료용 조성물 |
KR100849448B1 (ko) | 2002-08-22 | 2008-07-30 | 주식회사 바이오시너젠 | 라이소포스파티딜콜린 또는 그 유사체를 포함하는 선천성면역 증강 조성물 |
KR100842159B1 (ko) | 2002-03-25 | 2008-06-27 | 주식회사 바이오시너젠 | 라이소포스파티딜콜린 또는 그 유사체를 포함하는 급성호흡곤란 증후군 및 다발성 장기부전의 예방 및 치료용조성물 |
US8557861B2 (en) * | 2004-09-28 | 2013-10-15 | Mast Therapeutics, Inc. | Low oil emulsion compositions for delivering taxoids and other insoluble drugs |
JP5140577B2 (ja) * | 2005-03-31 | 2013-02-06 | タケダ カリフォルニア インコーポレイテッド | ヒドロキシステロイドデヒドロゲナーゼ阻害剤 |
CN101437490A (zh) | 2006-04-20 | 2009-05-20 | 安美基公司 | 稳定乳液配方 |
US20080145411A1 (en) | 2006-10-06 | 2008-06-19 | Kaneka Corporation | Composition of high absorbability for oral administration comprising oxidized coenzyme q10 |
AU2008329540B2 (en) * | 2007-11-28 | 2014-03-27 | Commonwealth Scientific And Industrial Research Organisation | Nanoemulsions |
US20090281065A1 (en) | 2008-05-09 | 2009-11-12 | Kemin Industries, Inc. | Use of Lysophospholipids to Treat Inflammation |
WO2011153513A2 (en) * | 2010-06-03 | 2011-12-08 | Latitude Pharma | Nanoemulsion composition containing vitamin k |
KR101315483B1 (ko) * | 2011-06-23 | 2013-10-07 | 주식회사 아리바이오 | 항생제 및 라이소포스파티딜콜린을 포함하는 면역 증강 또는 세균성 감염 질환 치료용 조성물 |
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2013
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2014
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US20160022711A1 (en) | 2016-01-28 |
US10265333B2 (en) | 2019-04-23 |
KR101951933B1 (ko) | 2019-02-25 |
JP2016518313A (ja) | 2016-06-23 |
EP2974715A4 (en) | 2016-03-16 |
WO2014142517A1 (ko) | 2014-09-18 |
KR20140112622A (ko) | 2014-09-24 |
EP2974715A1 (en) | 2016-01-20 |
ES2690393T3 (es) | 2018-11-20 |
CN105246487A (zh) | 2016-01-13 |
EP2974715B1 (en) | 2018-08-01 |
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