JPS57145810A - Immunological activator containing lysophospholipid and preparation thereof - Google Patents
Immunological activator containing lysophospholipid and preparation thereofInfo
- Publication number
- JPS57145810A JPS57145810A JP1339982A JP1339982A JPS57145810A JP S57145810 A JPS57145810 A JP S57145810A JP 1339982 A JP1339982 A JP 1339982A JP 1339982 A JP1339982 A JP 1339982A JP S57145810 A JPS57145810 A JP S57145810A
- Authority
- JP
- Japan
- Prior art keywords
- lysophospholipid
- immunological
- alkoxyl
- acyloxy
- incorporating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: To obtain a highly safe immunological activator capable of reducing the hemolytic action without affecting the immunological activating action of a lysophospholipid and angiopathy even on the continued parenteral use, by incorporating the lysophospholipid with a phospholipid.
CONSTITUTION: An immunological activator obtained by incorporating (A) a lysophospholipid, preferably a compound expressed by the formula (R1 is 5W22C acyloxy or 5W22C alkoxyl; R2 is H, OH, 1W5C acyloxy, 1W5C alkoxyl or R1 and R2 are mutually exchangeable; R3 is H or 1W5C alkyl) or a lysophospholipid consisting thereof essentially, particularly the compound obtained by decomposing lecithin, and (B) preferably a naturally occurring phospholipid, and in the dosage form of a dispersion in which the components are dispersed in a lipid cytoplasmic reticula having a particle diameter ≤0.5μ. The immunological activator may contain (C) a fat or oil, particularly edible oil, or (D) fatty emulsion.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1339982A JPS57145810A (en) | 1982-02-01 | 1982-02-01 | Immunological activator containing lysophospholipid and preparation thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1339982A JPS57145810A (en) | 1982-02-01 | 1982-02-01 | Immunological activator containing lysophospholipid and preparation thereof |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP11726279A Division JPS5840929B2 (en) | 1979-03-05 | 1979-09-14 | Anticancer agent containing lysolecithin and phospholipid and its manufacturing method |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57145810A true JPS57145810A (en) | 1982-09-09 |
JPS6348848B2 JPS6348848B2 (en) | 1988-09-30 |
Family
ID=11832034
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1339982A Granted JPS57145810A (en) | 1982-02-01 | 1982-02-01 | Immunological activator containing lysophospholipid and preparation thereof |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57145810A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001095914A1 (en) * | 2000-06-14 | 2001-12-20 | William Leslie Porter | Lipids for modulating immune response |
JP2016518313A (en) * | 2013-03-12 | 2016-06-23 | アリビオ, インコーポレーテッド | Lipid nanomaterial containing lysophosphatidylcholine or derivative thereof, and method for producing the same |
-
1982
- 1982-02-01 JP JP1339982A patent/JPS57145810A/en active Granted
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001095914A1 (en) * | 2000-06-14 | 2001-12-20 | William Leslie Porter | Lipids for modulating immune response |
JP2016518313A (en) * | 2013-03-12 | 2016-06-23 | アリビオ, インコーポレーテッド | Lipid nanomaterial containing lysophosphatidylcholine or derivative thereof, and method for producing the same |
Also Published As
Publication number | Publication date |
---|---|
JPS6348848B2 (en) | 1988-09-30 |
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