JP6236395B2 - イソソルビドカプリレート／カプレートの体臭防止剤及び発汗抑制剤における使用 - Google Patents
イソソルビドカプリレート／カプレートの体臭防止剤及び発汗抑制剤における使用 Download PDFInfo
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- JP6236395B2 JP6236395B2 JP2014541572A JP2014541572A JP6236395B2 JP 6236395 B2 JP6236395 B2 JP 6236395B2 JP 2014541572 A JP2014541572 A JP 2014541572A JP 2014541572 A JP2014541572 A JP 2014541572A JP 6236395 B2 JP6236395 B2 JP 6236395B2
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- Prior art keywords
- caprate
- composition
- caprylate
- isosorbide
- body odor
- Prior art date
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- 206010040904 Skin odour abnormal Diseases 0.000 title claims description 76
- KLDXJTOLSGUMSJ-JGWLITMVSA-N Isosorbide Chemical compound O[C@@H]1CO[C@@H]2[C@@H](O)CO[C@@H]21 KLDXJTOLSGUMSJ-JGWLITMVSA-N 0.000 title claims description 71
- 229960002479 isosorbide Drugs 0.000 title claims description 71
- WWZKQHOCKIZLMA-UHFFFAOYSA-M octanoate Chemical compound CCCCCCCC([O-])=O WWZKQHOCKIZLMA-UHFFFAOYSA-M 0.000 title claims description 62
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102011119033A DE102011119033A1 (de) | 2011-11-22 | 2011-11-22 | Verwendung von Isosorbidcaprylaten/capraten in Deodorantien und Antiperspirantien |
| DE102011119033.7 | 2011-11-22 | ||
| PCT/EP2012/004827 WO2013075826A2 (de) | 2011-11-22 | 2012-11-21 | Verwendung von isosorbidcaprylaten/capraten in deodorantien und antiperspirantien |
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| JP2017202466A Division JP6549670B2 (ja) | 2011-11-22 | 2017-10-19 | イソソルビドカプリレート／カプレートの体臭防止剤及び発汗抑制剤における使用 |
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| JP2014533667A JP2014533667A (ja) | 2014-12-15 |
| JP2014533667A5 JP2014533667A5 (enExample) | 2016-06-23 |
| JP6236395B2 true JP6236395B2 (ja) | 2017-11-22 |
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| JP2014541572A Expired - Fee Related JP6236395B2 (ja) | 2011-11-22 | 2012-11-21 | イソソルビドカプリレート／カプレートの体臭防止剤及び発汗抑制剤における使用 |
| JP2017202466A Expired - Fee Related JP6549670B2 (ja) | 2011-11-22 | 2017-10-19 | イソソルビドカプリレート／カプレートの体臭防止剤及び発汗抑制剤における使用 |
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| JP2017202466A Expired - Fee Related JP6549670B2 (ja) | 2011-11-22 | 2017-10-19 | イソソルビドカプリレート／カプレートの体臭防止剤及び発汗抑制剤における使用 |
Country Status (7)
| Country | Link |
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| US (1) | US20140322151A1 (enExample) |
| EP (2) | EP3300771B1 (enExample) |
| JP (2) | JP6236395B2 (enExample) |
| CN (1) | CN104302359B (enExample) |
| BR (1) | BR112014012246A2 (enExample) |
| DE (1) | DE102011119033A1 (enExample) |
| WO (1) | WO2013075826A2 (enExample) |
Cited By (1)
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| JP2018052947A (ja) * | 2011-11-22 | 2018-04-05 | クラリアント・ファイナンス・（ビーブイアイ）・リミテッド | イソソルビドカプリレート／カプレートの体臭防止剤及び発汗抑制剤における使用 |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102009022445A1 (de) | 2009-05-23 | 2009-12-24 | Clariant International Limited | Zusammensetzung enthaltend Sorbitanmonocaprylat und Alkohol |
| CN103717071B (zh) | 2011-08-04 | 2016-01-06 | 克拉里安特国际有限公司 | 包含异山梨醇单酯和n-羟基吡啶酮的组合物 |
| CN103747680B (zh) | 2011-08-04 | 2016-01-06 | 克拉里安特国际有限公司 | 包含异山梨醇单酯和异山梨醇二酯的组合物 |
| WO2013017264A1 (de) | 2011-08-04 | 2013-02-07 | Clariant International Ltd | Zusammensetzungen enthaltend isosorbidmonoester und alkohole, die mindestens eine aromatische gruppe enthalten |
| US9555117B2 (en) | 2011-08-04 | 2017-01-31 | Clariant International Ltd. | Use of isosorbide monoesters as thickeners |
| ES2562854T3 (es) | 2011-08-04 | 2016-03-08 | Clariant International Ltd | Empleo de monoésteres de isosorbida como productos activos fungicidas |
| CN110075310A (zh) | 2011-12-20 | 2019-08-02 | 维奥姆治疗有限公司 | 用于治疗真菌感染的局部油组合物 |
| FR2998569B1 (fr) * | 2012-11-26 | 2015-01-09 | Roquette Freres | Procede de fabrication de compositions de diesters de 1,4 : 3,6-dianhydrohexitol |
| WO2016090247A1 (en) * | 2014-12-05 | 2016-06-09 | Mary Kay Inc. | Cosmetic compositions |
| WO2016169833A1 (de) * | 2015-04-24 | 2016-10-27 | Basf Se | Isosorbiddiester als perlglanzmittel und trübungsmittel |
| US20180289003A1 (en) * | 2015-08-24 | 2018-10-11 | Smith & Nephew, Inc. | Synergistic antibacterial activity of medium polarity oils in combination with antibacterial agents on bacterial biofilms |
| DE102015225958A1 (de) * | 2015-12-18 | 2017-06-22 | Henkel Ag & Co. Kgaa | Kosmetische Mittel, enthaltend eine Kombination von mindestens zwei verschiedenen Wirkstoffen |
| JP2019510036A (ja) | 2016-03-31 | 2019-04-11 | ゴジョ・インダストリーズ・インコーポレイテッド | プロバイオティクス／プレバイオティクス有効成分を含む清浄剤組成物 |
| WO2017173240A1 (en) | 2016-03-31 | 2017-10-05 | Gojo Industries, Inc. | Antimicrobial peptide stimulating cleansing composition |
| GR1009087B (el) * | 2016-06-01 | 2017-08-11 | ΦΑΡΜΑΣΕΠΤ - ΕΙΣΑΓ - ΑΝΤΙΠΡΟΣΩΠΕΙΕΣ ΦΑΡΜΑΚΕΥΤΙΚΩΝ ΕΙΔΩΝ με δ.τ. "PHARMASEPT Ε.Π.Ε. | Συστατικο για την παραγωγη καλλυντικων προϊοντων |
| WO2017216722A2 (en) * | 2016-06-13 | 2017-12-21 | Vyome Biosciences Pvt. Ltd. | Synergistic antifungal compositions and methods thereof |
| BR112018075998A2 (pt) * | 2016-06-13 | 2019-04-02 | Vyome Therapeutics Limited. | composições antifúngicas sinérgicas e métodos das mesmas |
| EP3471693B1 (en) | 2016-06-17 | 2020-08-12 | Unilever PLC | Deodorant products |
| WO2018087147A1 (en) * | 2016-11-10 | 2018-05-17 | Givaudan Sa | Deodorizing agent comprising zinc neodecanoate |
| EP3544575A1 (en) | 2016-11-23 | 2019-10-02 | GOJO Industries, Inc. | Sanitizer composition with probiotic/prebiotic active ingredient |
| EP3892270A4 (en) | 2018-12-04 | 2022-08-17 | The Nisshin OilliO Group, Ltd. | Oil-based humectant and composition for external application to skin containing same |
| FR3108034B1 (fr) | 2020-03-11 | 2022-09-09 | Hyteck | Composition deodorante |
| WO2025103691A1 (en) * | 2023-11-13 | 2025-05-22 | Unilever Ip Holdings B.V. | Transparent scalp care composition |
| EP4424298A3 (en) * | 2024-05-18 | 2025-04-09 | Clariant International Ltd | Antimicrobial compositions |
Family Cites Families (11)
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|---|---|---|---|---|
| JP2507425B2 (ja) * | 1987-05-23 | 1996-06-12 | 新田ゼラチン株式会社 | 化粧料 |
| IL112649A (en) * | 1994-02-22 | 1999-12-22 | Curtis Helene Ind Inc | Topically effective compositions for application to the skin or hair |
| JPH08173787A (ja) | 1994-08-12 | 1996-07-09 | Lion Corp | 界面活性剤組成物 |
| JPH08187070A (ja) * | 1994-11-10 | 1996-07-23 | Lion Corp | 飲食品用抗菌剤及び飲食品 |
| JP3936968B2 (ja) * | 2000-04-27 | 2007-06-27 | 塩野香料株式会社 | 天然物由来の抗菌剤、抗菌性香料および、それらを含有する化粧品 |
| JP2002255774A (ja) * | 2001-03-02 | 2002-09-11 | Kao Corp | デオドラント剤 |
| DE102009001748A1 (de) | 2009-03-23 | 2010-09-30 | Evonik Goldschmidt Gmbh | Formulierungen enthaltend Sorbitancarbonsäureester |
| DE102009022444A1 (de) * | 2009-05-23 | 2010-01-07 | Clariant International Limited | Zusammensetzung enthaltend Sorbitanmonocaprylat und antimikrobielle Wirkstoffe |
| DE102009022445A1 (de) | 2009-05-23 | 2009-12-24 | Clariant International Limited | Zusammensetzung enthaltend Sorbitanmonocaprylat und Alkohol |
| EP2739148B1 (de) * | 2011-08-04 | 2016-09-28 | Clariant International Ltd | Zusammensetzungen enthaltend isosorbidmonoester und aliphatische vicinale diole |
| DE102011119033A1 (de) * | 2011-11-22 | 2012-09-06 | Clariant International Ltd. | Verwendung von Isosorbidcaprylaten/capraten in Deodorantien und Antiperspirantien |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018052947A (ja) * | 2011-11-22 | 2018-04-05 | クラリアント・ファイナンス・（ビーブイアイ）・リミテッド | イソソルビドカプリレート／カプレートの体臭防止剤及び発汗抑制剤における使用 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3300771A1 (de) | 2018-04-04 |
| CN104302359B (zh) | 2017-03-22 |
| JP6549670B2 (ja) | 2019-07-24 |
| WO2013075826A3 (de) | 2014-02-20 |
| CN104302359A (zh) | 2015-01-21 |
| WO2013075826A2 (de) | 2013-05-30 |
| EP2782645A2 (de) | 2014-10-01 |
| BR112014012246A2 (pt) | 2017-05-30 |
| EP3300771B1 (de) | 2020-06-17 |
| JP2018052947A (ja) | 2018-04-05 |
| EP2782645B1 (de) | 2017-10-18 |
| JP2014533667A (ja) | 2014-12-15 |
| DE102011119033A1 (de) | 2012-09-06 |
| US20140322151A1 (en) | 2014-10-30 |
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