JP6224097B2 - フェニルトリアゾール誘導体及びgabaa受受容体複合体を調節するための該フェニルトリアゾール誘導体の使用 - Google Patents

フェニルトリアゾール誘導体及びgabaa受受容体複合体を調節するための該フェニルトリアゾール誘導体の使用 Download PDF

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JP6224097B2
JP6224097B2 JP2015519034A JP2015519034A JP6224097B2 JP 6224097 B2 JP6224097 B2 JP 6224097B2 JP 2015519034 A JP2015519034 A JP 2015519034A JP 2015519034 A JP2015519034 A JP 2015519034A JP 6224097 B2 JP6224097 B2 JP 6224097B2
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JP2015521642A (ja
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ラーセン,ヤヌス・シュライバー
グスタフソン,マグヌス
イェッセン,カーステン
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サニオナ・エイピイエス
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2015519034A 2012-06-26 2013-06-25 フェニルトリアゾール誘導体及びgabaa受受容体複合体を調節するための該フェニルトリアゾール誘導体の使用 Expired - Fee Related JP6224097B2 (ja)

Applications Claiming Priority (5)

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US201261664287P 2012-06-26 2012-06-26
US61/664,287 2012-06-26
DKPA201270368 2012-06-26
DKPA201270368 2012-06-26
PCT/EP2013/063193 WO2014001281A1 (en) 2012-06-26 2013-06-25 A phenyl triazole derivative and its use for modulating the gabaa receptor complex

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JP2015521642A JP2015521642A (ja) 2015-07-30
JP2015521642A5 JP2015521642A5 (enExample) 2016-08-12
JP6224097B2 true JP6224097B2 (ja) 2017-11-01

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JP2015519034A Expired - Fee Related JP6224097B2 (ja) 2012-06-26 2013-06-25 フェニルトリアゾール誘導体及びgabaa受受容体複合体を調節するための該フェニルトリアゾール誘導体の使用

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US (2) US9206160B2 (enExample)
EP (1) EP2877463B1 (enExample)
JP (1) JP6224097B2 (enExample)
KR (1) KR20150033678A (enExample)
CN (1) CN104411699B (enExample)
AU (1) AU2013283487C1 (enExample)
CA (1) CA2876778A1 (enExample)
IL (1) IL236041A (enExample)
MX (1) MX357504B (enExample)
WO (1) WO2014001281A1 (enExample)

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EP3119744B1 (en) * 2014-03-18 2019-03-06 Algiax Pharmaceuticals GmbH 2-cyano-3-cyclopropyl-3-hydroxy-n-aryl-thioacrylamide derivatives
BR102019014802A2 (pt) 2018-07-20 2020-02-04 Boehringer Ingelheim Int difluorometil-fenil triazóis
HU231223B1 (hu) 2018-09-28 2022-01-28 Richter Gedeon Nyrt. GABAA A5 receptor modulátor hatású biciklusos vegyületek
EP3858965B1 (en) * 2020-01-28 2022-05-11 The Procter & Gamble Company Cleaning product
EP4126858A1 (en) 2020-03-26 2023-02-08 Richter Gedeon Nyrt. Dihydro-2-pyrrolo[3,4-c]pyridine derivatives as gabaa a5 receptor modulators
IL296716A (en) * 2020-03-26 2022-11-01 Richter Gedeon Nyrt History of naphthyridine and pyrido[4,3-c]pyridazine as gabaa alpha 5 receptor modulators
EP3992188A1 (en) * 2020-10-29 2022-05-04 Boehringer Ingelheim International GmbH Difluoromethyl-pyridin-2-yl triazoles
CN120943817A (zh) * 2020-08-05 2025-11-14 勃林格殷格翰国际有限公司 二氟甲基-吡啶-2-基三唑
IL310708A (en) * 2021-08-12 2024-04-01 Shanghai Simr Biotechnology Co Ltd The history of converted triazole, a method for its preparation, its pharmaceutical preparation and its use
WO2024023268A1 (en) 2022-07-29 2024-02-01 F. Hoffmann-La Roche Ag Characterisation of neurological dysfunction

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ATE414703T1 (de) 2005-09-19 2008-12-15 Hoffmann La Roche Isoxazolderivate als inverse gaba a alpha5 agonisten
AU2006301376A1 (en) 2005-10-11 2007-04-19 F. Hoffmann-La Roche Ag Isoxazole derivatives
CN101304994B (zh) 2005-11-09 2011-06-29 弗·哈夫曼-拉罗切有限公司 3-芳基-异噁唑-4-羰基-苯并呋喃衍生物
AU2006328602B2 (en) 2005-12-23 2012-05-31 F. Hoffmann-La Roche Ag Aryl-isoxazolo-4-yl-oxadiazole derivatives
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AU2013283487A1 (en) 2015-01-22
IL236041A0 (en) 2015-02-01
US20150152085A1 (en) 2015-06-04
CN104411699B (zh) 2017-06-13
MX2014014871A (es) 2015-06-17
US20160067234A1 (en) 2016-03-10
JP2015521642A (ja) 2015-07-30
KR20150033678A (ko) 2015-04-01
EP2877463B1 (en) 2018-11-07
CA2876778A1 (en) 2014-01-03
CN104411699A (zh) 2015-03-11
AU2013283487B2 (en) 2017-05-25
US9931329B2 (en) 2018-04-03
AU2013283487C1 (en) 2018-01-18
US9206160B2 (en) 2015-12-08
WO2014001281A1 (en) 2014-01-03
MX357504B (es) 2018-07-12
IL236041A (en) 2016-09-29
EP2877463A1 (en) 2015-06-03

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