JP6216494B2 - 熱サイクル装置及び熱サイクル装置の制御方法 - Google Patents

熱サイクル装置及び熱サイクル装置の制御方法 Download PDF

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Publication number
JP6216494B2
JP6216494B2 JP2012079766A JP2012079766A JP6216494B2 JP 6216494 B2 JP6216494 B2 JP 6216494B2 JP 2012079766 A JP2012079766 A JP 2012079766A JP 2012079766 A JP2012079766 A JP 2012079766A JP 6216494 B2 JP6216494 B2 JP 6216494B2
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JP
Japan
Prior art keywords
arrangement
heating unit
heating
reaction
unit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2012079766A
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English (en)
Japanese (ja)
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JP2013208067A5 (enExample
JP2013208067A (ja
Inventor
山口　明美
明美 山口
小枝　周史
周史 小枝
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seiko Epson Corp
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Seiko Epson Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seiko Epson Corp filed Critical Seiko Epson Corp
Priority to JP2012079766A priority Critical patent/JP6216494B2/ja
Priority to US13/796,498 priority patent/US8932833B2/en
Publication of JP2013208067A publication Critical patent/JP2013208067A/ja
Priority to US14/563,489 priority patent/US20150087026A1/en
Publication of JP2013208067A5 publication Critical patent/JP2013208067A5/ja
Application granted granted Critical
Publication of JP6216494B2 publication Critical patent/JP6216494B2/ja
Expired - Fee Related legal-status Critical Current
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B01L7/525—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B01L7/525—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones
    • B01L7/5255—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones by moving sample containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0673—Handling of plugs of fluid surrounded by immiscible fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0457—Moving fluids with specific forces or mechanical means specific forces passive flow or gravitation

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Clinical Laboratory Science (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2012079766A 2012-03-30 2012-03-30 熱サイクル装置及び熱サイクル装置の制御方法 Expired - Fee Related JP6216494B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2012079766A JP6216494B2 (ja) 2012-03-30 2012-03-30 熱サイクル装置及び熱サイクル装置の制御方法
US13/796,498 US8932833B2 (en) 2012-03-30 2013-03-12 Thermal cycler and control method of thermal cycler
US14/563,489 US20150087026A1 (en) 2012-03-30 2014-12-08 Thermal cycler and control method of thermal cycler

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2012079766A JP6216494B2 (ja) 2012-03-30 2012-03-30 熱サイクル装置及び熱サイクル装置の制御方法

Publications (3)

Publication Number Publication Date
JP2013208067A JP2013208067A (ja) 2013-10-10
JP2013208067A5 JP2013208067A5 (enExample) 2015-05-14
JP6216494B2 true JP6216494B2 (ja) 2017-10-18

Family

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Family Applications (1)

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JP2012079766A Expired - Fee Related JP6216494B2 (ja) 2012-03-30 2012-03-30 熱サイクル装置及び熱サイクル装置の制御方法

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Country Link
US (2) US8932833B2 (enExample)
JP (1) JP6216494B2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6216494B2 (ja) * 2012-03-30 2017-10-18 セイコーエプソン株式会社 熱サイクル装置及び熱サイクル装置の制御方法
JP5971463B2 (ja) 2012-03-30 2016-08-17 セイコーエプソン株式会社 熱サイクル装置及び熱サイクル装置の制御方法
JP2013208066A (ja) 2012-03-30 2013-10-10 Seiko Epson Corp 熱サイクル装置及び熱サイクル装置の制御方法
JP5967361B2 (ja) 2012-06-06 2016-08-10 セイコーエプソン株式会社 熱サイクル装置
US10406527B2 (en) * 2013-10-15 2019-09-10 Bio Molecular Systems Pty Ltd Thermocycler
JP2015154722A (ja) 2014-02-20 2015-08-27 セイコーエプソン株式会社 核酸増幅反応容器及び核酸増幅反応装置
JP2015223083A (ja) * 2014-05-26 2015-12-14 セイコーエプソン株式会社 核酸増幅反応装置の制御方法
KR102336308B1 (ko) 2014-12-26 2021-12-09 주식회사 미코바이오메드 반복 슬라이딩 구동 수단을 구비하는 pcr 장치 및 이를 이용하는 pcr 방법
TW201628718A (zh) * 2015-02-13 2016-08-16 Genereach Biotechnology Corp 加熱裝置以及具有該加熱裝置的生化反應器
WO2016145573A1 (zh) * 2015-03-13 2016-09-22 瑞基海洋生物科技股份有限公司 加热装置以及具有该加热装置的生化反应器
US10738272B2 (en) * 2016-06-27 2020-08-11 General Electric Company Heating assembly for a bioreactor and an associated method thereof
US11857974B2 (en) * 2020-03-24 2024-01-02 Bio-Rad Laboratories, Inc. Method and system for thermally controlling a chemical reaction in droplets
WO2024202886A1 (ja) * 2023-03-29 2024-10-03 国立研究開発法人産業技術総合研究所 核酸検出方法並びにヒドロゲルカプセル及びその分散液

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4949600B2 (ja) * 2000-09-14 2012-06-13 カリパー・ライフ・サイエンシズ・インク． 温度介在反応を行うためのマイクロ流体装置及び方法
JP2005034121A (ja) * 2003-07-15 2005-02-10 Nagasaki Prefecture 食中毒起因細菌の一括検出方法及びその試薬
WO2006074217A2 (en) * 2005-01-04 2006-07-13 Stratagene California Hot start polymerase reaction using a thermolabile blocker
WO2008091626A1 (en) * 2007-01-22 2008-07-31 Wafergen, Inc. Apparatus for high throughput chemical reactions
JP5196126B2 (ja) * 2007-12-10 2013-05-15 セイコーエプソン株式会社 生体試料反応装置および生体試料反応方法
JP2011174734A (ja) * 2010-02-23 2011-09-08 Seiko Epson Corp 検体反応装置及びバイオチップ
JP5862006B2 (ja) 2010-11-17 2016-02-16 セイコーエプソン株式会社 熱サイクル装置及び熱サイクル方法
JP5867668B2 (ja) * 2010-12-01 2016-02-24 セイコーエプソン株式会社 熱サイクル装置及び熱サイクル方法
JP2013208066A (ja) * 2012-03-30 2013-10-10 Seiko Epson Corp 熱サイクル装置及び熱サイクル装置の制御方法
JP6216494B2 (ja) * 2012-03-30 2017-10-18 セイコーエプソン株式会社 熱サイクル装置及び熱サイクル装置の制御方法

Also Published As

Publication number Publication date
US8932833B2 (en) 2015-01-13
US20150087026A1 (en) 2015-03-26
US20130260421A1 (en) 2013-10-03
JP2013208067A (ja) 2013-10-10

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