JP6192280B2 - レーザ光源装置およびレーザ顕微鏡 - Google Patents
レーザ光源装置およびレーザ顕微鏡 Download PDFInfo
- Publication number
- JP6192280B2 JP6192280B2 JP2012214454A JP2012214454A JP6192280B2 JP 6192280 B2 JP6192280 B2 JP 6192280B2 JP 2012214454 A JP2012214454 A JP 2012214454A JP 2012214454 A JP2012214454 A JP 2012214454A JP 6192280 B2 JP6192280 B2 JP 6192280B2
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- dispersion
- wavelength
- optical system
- laser light
- light source
- Prior art date
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- 230000003287 optical effect Effects 0.000 claims description 196
- 239000006185 dispersion Substances 0.000 claims description 175
- 238000006243 chemical reaction Methods 0.000 claims description 34
- 230000005284 excitation Effects 0.000 claims description 13
- 230000000694 effects Effects 0.000 claims description 12
- 238000007493 shaping process Methods 0.000 claims description 10
- 238000013459 approach Methods 0.000 claims description 9
- 238000001514 detection method Methods 0.000 claims description 5
- 230000002194 synthesizing effect Effects 0.000 claims description 4
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 230000001360 synchronised effect Effects 0.000 claims 1
- 238000003786 synthesis reaction Methods 0.000 claims 1
- 238000011144 upstream manufacturing Methods 0.000 claims 1
- 238000012986 modification Methods 0.000 description 14
- 230000004048 modification Effects 0.000 description 14
- 238000010586 diagram Methods 0.000 description 11
- 230000000638 stimulation Effects 0.000 description 6
- 238000002073 fluorescence micrograph Methods 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 210000001747 pupil Anatomy 0.000 description 2
- 230000000903 blocking effect Effects 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 230000001678 irradiating effect Effects 0.000 description 1
Images
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01S—DEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
- H01S3/00—Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range
- H01S3/005—Optical devices external to the laser cavity, specially adapted for lasers, e.g. for homogenisation of the beam or for manipulating laser pulses, e.g. pulse shaping
- H01S3/0057—Temporal shaping, e.g. pulse compression, frequency chirping
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0032—Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0052—Optical details of the image generation
- G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence
-
- G—PHYSICS
- G02—OPTICS
- G02F—OPTICAL DEVICES OR ARRANGEMENTS FOR THE CONTROL OF LIGHT BY MODIFICATION OF THE OPTICAL PROPERTIES OF THE MEDIA OF THE ELEMENTS INVOLVED THEREIN; NON-LINEAR OPTICS; FREQUENCY-CHANGING OF LIGHT; OPTICAL LOGIC ELEMENTS; OPTICAL ANALOGUE/DIGITAL CONVERTERS
- G02F1/00—Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics
- G02F1/35—Non-linear optics
- G02F1/353—Frequency conversion, i.e. wherein a light beam is generated with frequency components different from those of the incident light beams
- G02F1/3532—Arrangements of plural nonlinear devices for generating multi-colour light beams, e.g. arrangements of SHG, SFG, OPO devices for generating RGB light beams
-
- G—PHYSICS
- G02—OPTICS
- G02F—OPTICAL DEVICES OR ARRANGEMENTS FOR THE CONTROL OF LIGHT BY MODIFICATION OF THE OPTICAL PROPERTIES OF THE MEDIA OF THE ELEMENTS INVOLVED THEREIN; NON-LINEAR OPTICS; FREQUENCY-CHANGING OF LIGHT; OPTICAL LOGIC ELEMENTS; OPTICAL ANALOGUE/DIGITAL CONVERTERS
- G02F1/00—Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics
- G02F1/35—Non-linear optics
- G02F1/39—Non-linear optics for parametric generation or amplification of light, infrared or ultraviolet waves
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B2207/00—Coding scheme for general features or characteristics of optical elements and systems of subclass G02B, but not including elements and systems which would be classified in G02B6/00 and subgroups
- G02B2207/114—Two photon or multiphoton effect
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01S—DEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
- H01S3/00—Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range
- H01S3/005—Optical devices external to the laser cavity, specially adapted for lasers, e.g. for homogenisation of the beam or for manipulating laser pulses, e.g. pulse shaping
- H01S3/0092—Nonlinear frequency conversion, e.g. second harmonic generation [SHG] or sum- or difference-frequency generation outside the laser cavity
Landscapes
- Physics & Mathematics (AREA)
- Nonlinear Science (AREA)
- Optics & Photonics (AREA)
- General Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Electromagnetism (AREA)
- Plasma & Fusion (AREA)
- Engineering & Computer Science (AREA)
- Microscoopes, Condenser (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Optical Modulation, Optical Deflection, Nonlinear Optics, Optical Demodulation, Optical Logic Elements (AREA)
- Lasers (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012214454A JP6192280B2 (ja) | 2011-09-30 | 2012-09-27 | レーザ光源装置およびレーザ顕微鏡 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011217160 | 2011-09-30 | ||
| JP2011217160 | 2011-09-30 | ||
| JP2012214454A JP6192280B2 (ja) | 2011-09-30 | 2012-09-27 | レーザ光源装置およびレーザ顕微鏡 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013083970A JP2013083970A (ja) | 2013-05-09 |
| JP2013083970A5 JP2013083970A5 (enExample) | 2015-11-12 |
| JP6192280B2 true JP6192280B2 (ja) | 2017-09-06 |
Family
ID=47992558
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012214454A Active JP6192280B2 (ja) | 2011-09-30 | 2012-09-27 | レーザ光源装置およびレーザ顕微鏡 |
Country Status (2)
| Country | Link |
|---|---|
| US (1) | US9356413B2 (enExample) |
| JP (1) | JP6192280B2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102013227103B4 (de) * | 2013-09-03 | 2018-05-30 | Leica Microsystems Cms Gmbh | Mikroskop mit einer akustooptischen Vorrichtung |
| WO2015108991A2 (en) | 2014-01-17 | 2015-07-23 | Imra America, Inc. | Laser-based modification of transparent materials |
| JP2017513211A (ja) * | 2014-02-28 | 2017-05-25 | イムラ アメリカ インコーポレイテッド | 顕微鏡に適用される多波長超短パルスの生成及び放出 |
| CN103823309B (zh) * | 2014-03-12 | 2016-05-04 | 南开大学 | 一种时空分布可调的超短激光脉冲分束方法及装置 |
| CN103885166A (zh) * | 2014-03-28 | 2014-06-25 | 天津大学 | 基于布拉格衍射晶体的超高分辨非线性激发荧光显微系统 |
| JP6501451B2 (ja) * | 2014-03-31 | 2019-04-17 | キヤノン株式会社 | 光源装置およびそれを用いた情報取得装置 |
| CN103995362A (zh) * | 2014-04-24 | 2014-08-20 | 南开大学 | 一种连续调节脉冲间隔的方法和装置 |
| US10156771B2 (en) * | 2015-12-01 | 2018-12-18 | The United States Of America, As Represented By The Secretary Of Commerce | Optical parametric oscillator |
| JP6746371B2 (ja) * | 2016-05-13 | 2020-08-26 | キヤノン株式会社 | 光源装置及び情報取得装置 |
| CN105742953A (zh) * | 2016-05-13 | 2016-07-06 | 上海朗研光电科技有限公司 | 一种用脉冲堆积放大实现高功率超短脉冲激光的装置与方法 |
| FR3092442B1 (fr) * | 2019-02-04 | 2022-12-30 | Amplitude Systemes | Système laser à superposition temporelle d’impulsions |
| US11808568B2 (en) * | 2021-02-05 | 2023-11-07 | Shangqing Liu | Method of inner light layer illumination by multi-beam interference and apparatuses for imaging in turbid media |
| US20220258277A1 (en) * | 2021-02-12 | 2022-08-18 | Joyce Liu | Laser Beam Processing Apparatuses and Correspondent Method Using Multi-beam Interference |
| CN119812918B (zh) * | 2024-12-31 | 2025-11-04 | 中国科学院长春光学精密机械与物理研究所 | 大能量碟片激光器热镜效应控制系统 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10056382B4 (de) | 2000-11-14 | 2004-07-01 | Leica Microsystems Heidelberg Gmbh | Scanmikroskop |
| DE10347712A1 (de) * | 2003-10-14 | 2005-05-12 | Leica Microsystems | Rastermikroskop |
| JP2005172776A (ja) * | 2003-12-07 | 2005-06-30 | Kazuyoshi Ito | 複数の波長依存性物質を含む試料の分析方法及び分析装置 |
| FR2877103B1 (fr) * | 2004-10-22 | 2012-02-10 | Mauna Kea Technologies | Systeme et procede d'imagerie microscopique multiphotonique fibre d'un echantillon |
| DE102005059338A1 (de) * | 2005-12-08 | 2007-06-14 | Carl Zeiss Jena Gmbh | Verfahren und Anordnung zur Untersuchung von Proben |
| JP5185695B2 (ja) * | 2008-05-23 | 2013-04-17 | オリンパス株式会社 | レーザ顕微鏡装置及び標本画像取得方法 |
| JP2011017965A (ja) * | 2009-07-10 | 2011-01-27 | Nikon Corp | 顕微鏡装置、および顕微鏡装置の制御方法 |
| JP2011128287A (ja) * | 2009-12-16 | 2011-06-30 | Nikon Corp | 多光子顕微鏡 |
| JP2011146463A (ja) * | 2010-01-13 | 2011-07-28 | Nikon Corp | レーザ発振装置 |
| WO2011091316A2 (en) * | 2010-01-22 | 2011-07-28 | Newport Corporation | Broadly tunable optical parametric oscillator |
-
2012
- 2012-09-24 US US13/625,228 patent/US9356413B2/en active Active
- 2012-09-27 JP JP2012214454A patent/JP6192280B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US9356413B2 (en) | 2016-05-31 |
| JP2013083970A (ja) | 2013-05-09 |
| US20130083816A1 (en) | 2013-04-04 |
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