JP6182141B2 - 抗真菌剤の効果を高めるアルギネートオリゴマーの使用 - Google Patents

抗真菌剤の効果を高めるアルギネートオリゴマーの使用 Download PDF

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JP6182141B2
JP6182141B2 JP2014530315A JP2014530315A JP6182141B2 JP 6182141 B2 JP6182141 B2 JP 6182141B2 JP 2014530315 A JP2014530315 A JP 2014530315A JP 2014530315 A JP2014530315 A JP 2014530315A JP 6182141 B2 JP6182141 B2 JP 6182141B2
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tissue
mer
subject
antifungal agent
alginate
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JP2014527079A (ja
JP2014527079A5 (enExample
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エドヴァル オンソイェン
エドヴァル オンソイェン
アルネ デッセン
アルネ デッセン
デイビッド ウィリアム トーマス
デイビッド ウィリアム トーマス
カティヤ エテル ヒル
カティヤ エテル ヒル
ホーバー スレッタ
ホーバー スレッタ
アン トゥンデルヴィク
アン トゥンデルヴィク
ゲイル クリンケンベルグ
ゲイル クリンケンベルグ
ロルフ ミルヴォルド
ロルフ ミルヴォルド
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アルギファルマ エーエス
アルギファルマ エーエス
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02—Amines; Quaternary ammonium compounds
    • A01N33/04—Nitrogen directly attached to aliphatic or cycloaliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/14—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings
    • A01N43/16—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings with oxygen as the ring hetero atom
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647—Triazoles; Hydrogenated triazoles
    • A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/734—Alginic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
JP2014530315A 2011-09-15 2012-09-14 抗真菌剤の効果を高めるアルギネートオリゴマーの使用 Active JP6182141B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1116010.8 2011-09-15
GBGB1116010.8A GB201116010D0 (en) 2011-09-15 2011-09-15 Use of alginate oligomers to enhance the effects of antifungal agents
PCT/GB2012/052274 WO2013038197A1 (en) 2011-09-15 2012-09-14 Use of alginate oligomers to enhance the effects of antifungal agents

Publications (3)

Publication Number Publication Date
JP2014527079A JP2014527079A (ja) 2014-10-09
JP2014527079A5 JP2014527079A5 (enExample) 2015-11-05
JP6182141B2 true JP6182141B2 (ja) 2017-08-16

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JP2014530315A Active JP6182141B2 (ja) 2011-09-15 2012-09-14 抗真菌剤の効果を高めるアルギネートオリゴマーの使用

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Country Link
US (1) US20150126467A1 (enExample)
EP (1) EP2755481B1 (enExample)
JP (1) JP6182141B2 (enExample)
DK (1) DK2755481T3 (enExample)
ES (1) ES2798775T3 (enExample)
GB (1) GB201116010D0 (enExample)
WO (1) WO2013038197A1 (enExample)

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WO2014147869A1 (ja) * 2013-03-22 2014-09-25 Mizuta Youichi 植物組織の培養用培地の製造方法及び植物組織の培養方法並びに滅菌処理剤、殺菌処理剤、及び植物組織培養用培地組成物
JP6185157B2 (ja) * 2013-05-30 2017-08-23 蘇州科景生物医薬科技有限公司 多機能組成物並びにその作製方法及び使用
CN104435823B (zh) * 2014-11-14 2018-02-27 西藏月王藏药科技有限公司 一种青稞红曲藏药饮片的制备方法
CN110198959B (zh) 2017-01-03 2023-03-28 北卡罗米纳大学查佩尔希尔分校 释放一氧化氮的海藻酸盐作为可生物降解抗菌支架和相关方法
JP7112706B2 (ja) * 2017-01-16 2022-08-04 御木本製薬株式会社 抗菌性組成物並びに該抗菌性組成物を配合した皮膚外用剤
US10548948B2 (en) * 2017-03-02 2020-02-04 The United States Of America As Represented By The Secretary Of The Navy Methods of treating fungal infections
EP3600338A4 (en) 2017-03-28 2020-10-28 The University of North Carolina at Chapel Hill NITRIC OXIDE RELEASING POLYAMINOGLYCOSIDES AS BIODEGRADABLE ANTIBACTERIAL SCAFFOLDS AND RELATED PROCESSES
JP2021503029A (ja) 2017-11-15 2021-02-04 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒルＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｎｏｒｔｈ Ｃａｒｏｌｉｎａ Ａｔ Ｃｈａｐｅｌ Ｈｉｌｌ 抗菌性足場としての一酸化窒素放出性超分岐化合物およびそれに関する方法
CN107904179B (zh) * 2017-12-18 2020-10-23 云南天禾地生物科技股份有限公司 一株兼具植物促生长和抗病性的罗伦隐球酵母及其应用
AU2019231712B2 (en) 2018-03-06 2025-04-10 The University Of North Carolina At Chapel Hill Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds and methods pertaining thereto
US20210030891A1 (en) * 2018-03-19 2021-02-04 Algipharma As Use of alginate oligomers to enhance the translocation of micro/nanoparticles across mucus layers
CN113383019B (zh) 2018-12-28 2023-11-17 北卡罗来纳大学教堂山分校 一氧化氮释放型抗菌聚合物和由其制成的支架和其相关方法
EP3995317A1 (en) * 2019-04-08 2022-05-11 Main Choice Paper Products Limited Germ-repellent book and food paper packaging, and method of manufacture
EP3837977A1 (en) 2019-12-19 2021-06-23 Université de Bourgogne Use of alginates oligomers to improve plant protection against pathogens
DE102020101110A1 (de) 2020-01-17 2021-07-22 Beuth Hochschule Für Technik Berlin Antimykotische Aktivitäten von Hydrogelen auf Basis von Polysacchariden
CN111701013A (zh) * 2020-07-02 2020-09-25 深圳市恩瑜生物科技有限公司 一种具有治疗真菌感染的外用药物及制备方法
CN113430125B (zh) * 2021-07-27 2022-11-08 塔里木大学 一种高酯化力与糖化力的混合菌剂及其培养方法
CN114009440A (zh) * 2021-11-22 2022-02-08 兰州大学 阿巴芬净在防治农业病原菌中的用途
US20230346101A1 (en) * 2022-04-29 2023-11-02 Distinct Dermatology Inc. Treatment of fungal nail infection

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US5169840A (en) 1991-03-27 1992-12-08 Nobipols Forskningsstiftelse Diequatorially bound β-1, 4 polyuronates and use of same for cytokine stimulation
US5217493A (en) * 1992-03-11 1993-06-08 Board Of Regents, The University Of Texas System Antibacterial coated medical implants
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EP0807631B1 (en) * 1996-05-15 2003-03-12 Sankyo Company Limited Tricyclic compounds having fungicidal activity, their preparation and their use
NO305033B1 (no) 1997-05-09 1999-03-22 Algipharma As Fremgangsmate for fremstilling av uronsyreblokker fra alginat
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NO326145B1 (no) 2001-11-30 2008-10-06 Fmc Biopolymer As Fremgangsmate for a stimulere vektokning hos pattedyr, fugler og krypdyr.
NO20023581D0 (no) 2002-07-26 2002-07-26 Fmc Biopolymer As Nye mutantstammer av Pseudomonas fluorescens og varianter derav, metoder for produksjon og bruk derav til produksjon avalginat
GB2430881B (en) 2005-10-06 2010-10-13 Ntnu Technology Transfer As Oligoelectrolyte polyols for the treatment of mucosal hyperviscosity
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Also Published As

Publication number Publication date
EP2755481B1 (en) 2020-03-18
DK2755481T3 (da) 2020-06-15
ES2798775T3 (es) 2020-12-14
WO2013038197A1 (en) 2013-03-21
EP2755481A1 (en) 2014-07-23
JP2014527079A (ja) 2014-10-09
GB201116010D0 (en) 2011-10-26
US20150126467A1 (en) 2015-05-07

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