ES2798775T3 - Uso de oligómeros de alginato para reforzar los efectos de agentes antifúngicos - Google Patents

Info

Publication number

ES2798775T3

ES2798775T3 ES12766466T ES12766466T ES2798775T3 ES 2798775 T3 ES2798775 T3 ES 2798775T3 ES 12766466 T ES12766466 T ES 12766466T ES 12766466 T ES12766466 T ES 12766466T ES 2798775 T3 ES2798775 T3 ES 2798775T3

Authority

ES

Spain

Prior art keywords

fungus

antifungal agent

subject

alginate

alginate oligomer

Prior art date

2011-09-15

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Active

Links

• Espacenet
• Global Dossier
• Discuss

• 229940121375 antifungal agent Drugs 0.000 title claims abstract description 407
• 239000003429 antifungal agent Substances 0.000 title claims abstract description 379
• 235000010443 alginic acid Nutrition 0.000 title claims abstract description 343
• 229920000615 alginic acid Polymers 0.000 title claims abstract description 343
• FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 title claims abstract description 319
• 229940072056 alginate Drugs 0.000 title claims abstract description 316
• 230000000694 effects Effects 0.000 title description 36
• 241000233866 Fungi Species 0.000 claims abstract description 353
• 238000000034 method Methods 0.000 claims abstract description 80
• 230000012010 growth Effects 0.000 claims abstract description 65
• 229960000988 nystatin Drugs 0.000 claims abstract description 58
• VQOXZBDYSJBXMA-NQTDYLQESA-N nystatin A1 Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/CC/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 VQOXZBDYSJBXMA-NQTDYLQESA-N 0.000 claims abstract description 58
• APKFDSVGJQXUKY-KKGHZKTASA-N Amphotericin-B Natural products O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1C=CC=CC=CC=CC=CC=CC=C[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 APKFDSVGJQXUKY-KKGHZKTASA-N 0.000 claims abstract description 51
• APKFDSVGJQXUKY-INPOYWNPSA-N amphotericin B Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 APKFDSVGJQXUKY-INPOYWNPSA-N 0.000 claims abstract description 51
• 229960003942 amphotericin b Drugs 0.000 claims abstract description 51
• 229960004884 fluconazole Drugs 0.000 claims abstract description 50
• RFHAOTPXVQNOHP-UHFFFAOYSA-N fluconazole Chemical compound C1=NC=NN1CC(C=1C(=CC(F)=CC=1)F)(O)CN1C=NC=N1 RFHAOTPXVQNOHP-UHFFFAOYSA-N 0.000 claims abstract description 50
• BYBLEWFAAKGYCD-UHFFFAOYSA-N Miconazole Chemical compound ClC1=CC(Cl)=CC=C1COC(C=1C(=CC(Cl)=CC=1)Cl)CN1C=NC=C1 BYBLEWFAAKGYCD-UHFFFAOYSA-N 0.000 claims abstract description 33
• 229960002509 miconazole Drugs 0.000 claims abstract description 33
• 241000222122 Candida albicans Species 0.000 claims abstract description 31
• 229960002722 terbinafine Drugs 0.000 claims abstract description 29
• DOMXUEMWDBAQBQ-WEVVVXLNSA-N terbinafine Chemical group C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 DOMXUEMWDBAQBQ-WEVVVXLNSA-N 0.000 claims abstract description 29
• 230000035899 viability Effects 0.000 claims abstract description 23
• 241000221204 Cryptococcus neoformans Species 0.000 claims abstract description 20
• BCEHBSKCWLPMDN-MGPLVRAMSA-N voriconazole Chemical compound C1([C@H](C)[C@](O)(CN2N=CN=C2)C=2C(=CC(F)=CC=2)F)=NC=NC=C1F BCEHBSKCWLPMDN-MGPLVRAMSA-N 0.000 claims abstract description 20
• 229960004740 voriconazole Drugs 0.000 claims abstract description 20
• 241001508813 Clavispora lusitaniae Species 0.000 claims abstract description 19
• 201000007336 Cryptococcosis Diseases 0.000 claims abstract description 19
• 241000222178 Candida tropicalis Species 0.000 claims abstract description 18
• 229940095731 candida albicans Drugs 0.000 claims abstract description 17
• 238000000338 in vitro Methods 0.000 claims abstract description 16
• 241000228197 Aspergillus flavus Species 0.000 claims abstract description 14
• 241000235645 Pichia kudriavzevii Species 0.000 claims abstract description 13
• 241001225321 Aspergillus fumigatus Species 0.000 claims abstract description 11
• 229940091771 aspergillus fumigatus Drugs 0.000 claims abstract description 11
• 241000228245 Aspergillus niger Species 0.000 claims abstract description 10
• 241000222173 Candida parapsilosis Species 0.000 claims abstract description 8
• 229940055022 candida parapsilosis Drugs 0.000 claims abstract description 8
• 239000000203 mixture Substances 0.000 claims description 78
• 208000015181 infectious disease Diseases 0.000 claims description 73
• 238000011282 treatment Methods 0.000 claims description 61
• 208000027418 Wounds and injury Diseases 0.000 claims description 51
• 239000000463 material Substances 0.000 claims description 43
• 206010052428 Wound Diseases 0.000 claims description 41
• 210000004027 cell Anatomy 0.000 claims description 41
• 241001465754 Metazoa Species 0.000 claims description 40
• 238000006116 polymerization reaction Methods 0.000 claims description 39
• 239000000047 product Substances 0.000 claims description 34
• 235000013305 food Nutrition 0.000 claims description 28
• 210000001519 tissue Anatomy 0.000 claims description 28
• 239000000178 monomer Substances 0.000 claims description 25
• XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 25
• 208000014674 injury Diseases 0.000 claims description 23
• 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims description 22
• 230000001684 chronic effect Effects 0.000 claims description 17
• 230000002829 reductive effect Effects 0.000 claims description 15
• 230000008733 trauma Effects 0.000 claims description 13
• 206010035664 Pneumonia Diseases 0.000 claims description 12
• 230000001154 acute effect Effects 0.000 claims description 12
• 230000003115 biocidal effect Effects 0.000 claims description 12
• 238000009472 formulation Methods 0.000 claims description 12
• 208000023504 respiratory system disease Diseases 0.000 claims description 11
• 201000003883 Cystic fibrosis Diseases 0.000 claims description 10
• 210000004072 lung Anatomy 0.000 claims description 10
• 210000003491 skin Anatomy 0.000 claims description 10
• XOOUIPVCVHRTMJ-UHFFFAOYSA-L zinc stearate Chemical compound [Zn+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O XOOUIPVCVHRTMJ-UHFFFAOYSA-L 0.000 claims description 10
• 230000036541 health Effects 0.000 claims description 9
• 238000002360 preparation method Methods 0.000 claims description 9
• 208000006673 asthma Diseases 0.000 claims description 8
• 238000012545 processing Methods 0.000 claims description 8
• 210000003709 heart valve Anatomy 0.000 claims description 7
• 230000028327 secretion Effects 0.000 claims description 7
• 238000003860 storage Methods 0.000 claims description 7
• 206010040047 Sepsis Diseases 0.000 claims description 6
• 235000013361 beverage Nutrition 0.000 claims description 6
• 210000002615 epidermis Anatomy 0.000 claims description 6
• 210000000987 immune system Anatomy 0.000 claims description 6
• 210000000214 mouth Anatomy 0.000 claims description 6
• 210000000056 organ Anatomy 0.000 claims description 6
• 206010014561 Emphysema Diseases 0.000 claims description 5
• 206010061598 Immunodeficiency Diseases 0.000 claims description 5
• 206010028980 Neoplasm Diseases 0.000 claims description 5
• 230000008030 elimination Effects 0.000 claims description 5
• 238000003379 elimination reaction Methods 0.000 claims description 5
• 230000003511 endothelial effect Effects 0.000 claims description 5
• 210000002307 prostate Anatomy 0.000 claims description 5
• 201000009890 sinusitis Diseases 0.000 claims description 5
• 206010040070 Septic Shock Diseases 0.000 claims description 4
• 210000004369 blood Anatomy 0.000 claims description 4
• 239000008280 blood Substances 0.000 claims description 4
• 210000001124 body fluid Anatomy 0.000 claims description 4
• 239000010839 body fluid Substances 0.000 claims description 4
• 201000011510 cancer Diseases 0.000 claims description 4
• 239000006143 cell culture medium Substances 0.000 claims description 4
• 239000002537 cosmetic Substances 0.000 claims description 4
• 230000036303 septic shock Effects 0.000 claims description 4
• 239000002689 soil Substances 0.000 claims description 4
• 230000001919 adrenal effect Effects 0.000 claims description 3
• 238000004378 air conditioning Methods 0.000 claims description 3
• 210000000988 bone and bone Anatomy 0.000 claims description 3
• 210000001175 cerebrospinal fluid Anatomy 0.000 claims description 3
• 238000005553 drilling Methods 0.000 claims description 3
• 230000002357 endometrial effect Effects 0.000 claims description 3
• 210000001035 gastrointestinal tract Anatomy 0.000 claims description 3
• 239000010985 leather Substances 0.000 claims description 3
• 239000000314 lubricant Substances 0.000 claims description 3
• 230000003387 muscular Effects 0.000 claims description 3
• 230000001537 neural effect Effects 0.000 claims description 3
• 230000002611 ovarian Effects 0.000 claims description 3
• 230000001817 pituitary effect Effects 0.000 claims description 3
• 238000005057 refrigeration Methods 0.000 claims description 3
• 210000002345 respiratory system Anatomy 0.000 claims description 3
• 230000002381 testicular Effects 0.000 claims description 3
• 210000001685 thyroid gland Anatomy 0.000 claims description 3
• 239000002699 waste material Substances 0.000 claims description 3
• 208000030507 AIDS Diseases 0.000 claims description 2
• 208000011231 Crohn disease Diseases 0.000 claims description 2
• 206010058467 Lung neoplasm malignant Diseases 0.000 claims description 2
• 208000002720 Malnutrition Diseases 0.000 claims description 2
• 206010036790 Productive cough Diseases 0.000 claims description 2
• 206010067584 Type 1 diabetes mellitus Diseases 0.000 claims description 2
• 230000001476 alcoholic effect Effects 0.000 claims description 2
• 230000001363 autoimmune Effects 0.000 claims description 2
• 206010006451 bronchitis Diseases 0.000 claims description 2
• 238000002512 chemotherapy Methods 0.000 claims description 2
• 210000000795 conjunctiva Anatomy 0.000 claims description 2
• 239000003651 drinking water Substances 0.000 claims description 2
• 235000020188 drinking water Nutrition 0.000 claims description 2
• 210000000959 ear middle Anatomy 0.000 claims description 2
• 210000001508 eye Anatomy 0.000 claims description 2
• 230000002363 herbicidal effect Effects 0.000 claims description 2
• 239000004009 herbicide Substances 0.000 claims description 2
• 201000005202 lung cancer Diseases 0.000 claims description 2
• 208000020816 lung neoplasm Diseases 0.000 claims description 2
• 235000000824 malnutrition Nutrition 0.000 claims description 2
• 230000001071 malnutrition Effects 0.000 claims description 2
• 208000015380 nutritional deficiency disease Diseases 0.000 claims description 2
• 210000004303 peritoneum Anatomy 0.000 claims description 2
• 210000002381 plasma Anatomy 0.000 claims description 2
• 238000001959 radiotherapy Methods 0.000 claims description 2
• 210000005000 reproductive tract Anatomy 0.000 claims description 2
• 206010039073 rheumatoid arthritis Diseases 0.000 claims description 2
• 210000004761 scalp Anatomy 0.000 claims description 2
• 210000000582 semen Anatomy 0.000 claims description 2
• 210000002966 serum Anatomy 0.000 claims description 2
• 239000010865 sewage Substances 0.000 claims description 2
• 210000003802 sputum Anatomy 0.000 claims description 2
• 208000024794 sputum Diseases 0.000 claims description 2
• 150000003431 steroids Chemical class 0.000 claims description 2
• 239000003104 tissue culture media Substances 0.000 claims description 2
• 210000004026 tunica intima Anatomy 0.000 claims description 2
• 210000001635 urinary tract Anatomy 0.000 claims description 2
• 230000002440 hepatic effect Effects 0.000 claims 2
• 239000002361 compost Substances 0.000 claims 1
• 239000002917 insecticide Substances 0.000 claims 1
• 239000003090 pesticide formulation Substances 0.000 claims 1
• 230000002401 inhibitory effect Effects 0.000 abstract description 29
• 239000000417 fungicide Substances 0.000 description 82
• -1 antiseptics Substances 0.000 description 66
• 230000002538 fungal effect Effects 0.000 description 58
• 206010017533 Fungal infection Diseases 0.000 description 47
• 241000196324 Embryophyta Species 0.000 description 44
• 208000031888 Mycoses Diseases 0.000 description 44
• AEMOLEFTQBMNLQ-VANFPWTGSA-N D-mannopyranuronic acid Chemical compound OC1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@@H]1O AEMOLEFTQBMNLQ-VANFPWTGSA-N 0.000 description 27
• AEMOLEFTQBMNLQ-BZINKQHNSA-N D-Guluronic Acid Chemical compound OC1O[C@H](C(O)=O)[C@H](O)[C@@H](O)[C@H]1O AEMOLEFTQBMNLQ-BZINKQHNSA-N 0.000 description 26
• 230000000843 anti-fungal effect Effects 0.000 description 26
• 239000002609 medium Substances 0.000 description 26
• 239000000499 gel Substances 0.000 description 24
• 239000004599 antimicrobial Substances 0.000 description 22
• 239000000243 solution Substances 0.000 description 22
• 238000003556 assay Methods 0.000 description 21
• 230000006378 damage Effects 0.000 description 21
• 230000009467 reduction Effects 0.000 description 20
• 241000894007 species Species 0.000 description 20
• 235000010633 broth Nutrition 0.000 description 19
• 239000003795 chemical substances by application Substances 0.000 description 19
• 239000003814 drug Substances 0.000 description 19
• 238000012360 testing method Methods 0.000 description 19
• 241000228212 Aspergillus Species 0.000 description 17
• 244000005700 microbiome Species 0.000 description 17
• 239000002023 wood Substances 0.000 description 17
• 241000222120 Candida <Saccharomycetales> Species 0.000 description 16
• 239000002253 acid Substances 0.000 description 15
• 230000035876 healing Effects 0.000 description 15
• 229920000642 polymer Polymers 0.000 description 15
• 102000004190 Enzymes Human genes 0.000 description 14
• 108090000790 Enzymes Proteins 0.000 description 14
• 108090001066 Racemases and epimerases Proteins 0.000 description 14
• 230000000845 anti-microbial effect Effects 0.000 description 14
• 229940079593 drug Drugs 0.000 description 14
• 229940088598 enzyme Drugs 0.000 description 14
• 238000011534 incubation Methods 0.000 description 14
• 238000004519 manufacturing process Methods 0.000 description 14
• 241000223218 Fusarium Species 0.000 description 13
• 239000007788 liquid Substances 0.000 description 13
• 230000002685 pulmonary effect Effects 0.000 description 13
• UHPMCKVQTMMPCG-UHFFFAOYSA-N 5,8-dihydroxy-2-methoxy-6-methyl-7-(2-oxopropyl)naphthalene-1,4-dione Chemical compound CC1=C(CC(C)=O)C(O)=C2C(=O)C(OC)=CC(=O)C2=C1O UHPMCKVQTMMPCG-UHFFFAOYSA-N 0.000 description 12
• 241000223600 Alternaria Species 0.000 description 12
• IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 12
• 102000004879 Racemases and epimerases Human genes 0.000 description 12
• 150000002500 ions Chemical class 0.000 description 12
• 235000013399 edible fruits Nutrition 0.000 description 11
• 230000001225 therapeutic effect Effects 0.000 description 11
• KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 description 10
• 239000013543 active substance Substances 0.000 description 10
• 150000001875 compounds Chemical class 0.000 description 10
• 241000589149 Azotobacter vinelandii Species 0.000 description 9
• PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 9
• FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 9
• AEMOLEFTQBMNLQ-BKBMJHBISA-N alpha-D-galacturonic acid Chemical compound O[C@H]1O[C@H](C(O)=O)[C@H](O)[C@H](O)[C@H]1O AEMOLEFTQBMNLQ-BKBMJHBISA-N 0.000 description 9
• 201000003984 candidiasis Diseases 0.000 description 9
• 210000004209 hair Anatomy 0.000 description 9
• RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 description 9
• 230000003389 potentiating effect Effects 0.000 description 9
• 108090000623 proteins and genes Proteins 0.000 description 9
• 230000010076 replication Effects 0.000 description 9
• 229920001817 Agar Polymers 0.000 description 8
• 241000894006 Bacteria Species 0.000 description 8
• VOVIALXJUBGFJZ-KWVAZRHASA-N Budesonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1C[C@H]3OC(CCC)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O VOVIALXJUBGFJZ-KWVAZRHASA-N 0.000 description 8
• 206010007134 Candida infections Diseases 0.000 description 8
• WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 8
• 239000008272 agar Substances 0.000 description 8
• 230000009286 beneficial effect Effects 0.000 description 8
• WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 8
• 230000015572 biosynthetic process Effects 0.000 description 8
• 229960004436 budesonide Drugs 0.000 description 8
• 210000000170 cell membrane Anatomy 0.000 description 8
• 238000002474 experimental method Methods 0.000 description 8
• 230000000855 fungicidal effect Effects 0.000 description 8
• 239000003921 oil Substances 0.000 description 8
• 150000004291 polyenes Chemical class 0.000 description 8
• 208000024891 symptom Diseases 0.000 description 8
• 206010005098 Blastomycosis Diseases 0.000 description 7
• 241000195493 Cryptophyta Species 0.000 description 7
• LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 7
• 208000002474 Tinea Diseases 0.000 description 7
• NDAUXUAQIAJITI-UHFFFAOYSA-N albuterol Chemical compound CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1 NDAUXUAQIAJITI-UHFFFAOYSA-N 0.000 description 7
• 238000011109 contamination Methods 0.000 description 7
• 230000007423 decrease Effects 0.000 description 7
• 239000012528 membrane Substances 0.000 description 7
• 239000008194 pharmaceutical composition Substances 0.000 description 7
• 229920003023 plastic Polymers 0.000 description 7
• 239000004033 plastic Substances 0.000 description 7
• 239000000843 powder Substances 0.000 description 7
• 230000002265 prevention Effects 0.000 description 7
• 229960002052 salbutamol Drugs 0.000 description 7
• 239000004094 surface-active agent Substances 0.000 description 7
• 241000223205 Coccidioides immitis Species 0.000 description 6
• 206010016936 Folliculitis Diseases 0.000 description 6
• 241000555676 Malassezia Species 0.000 description 6
• 241000589516 Pseudomonas Species 0.000 description 6
• 238000004458 analytical method Methods 0.000 description 6
• 239000003242 anti bacterial agent Substances 0.000 description 6
• 239000011248 coating agent Substances 0.000 description 6
• 238000000576 coating method Methods 0.000 description 6
• 201000003486 coccidioidomycosis Diseases 0.000 description 6
• 201000010099 disease Diseases 0.000 description 6
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 6
• 239000008103 glucose Substances 0.000 description 6
• KEWHKYJURDBRMN-ZEODDXGYSA-M ipratropium bromide hydrate Chemical compound O.[Br-].O([C@H]1C[C@H]2CC[C@@H](C1)[N@@+]2(C)C(C)C)C(=O)C(CO)C1=CC=CC=C1 KEWHKYJURDBRMN-ZEODDXGYSA-M 0.000 description 6
• 210000004379 membrane Anatomy 0.000 description 6
• 230000000813 microbial effect Effects 0.000 description 6
• 239000000546 pharmaceutical excipient Substances 0.000 description 6
• 239000011780 sodium chloride Substances 0.000 description 6
• 239000007787 solid Substances 0.000 description 6
• 238000007920 subcutaneous administration Methods 0.000 description 6
• 239000000725 suspension Substances 0.000 description 6
• 230000009885 systemic effect Effects 0.000 description 6
• 235000001674 Agaricus brunnescens Nutrition 0.000 description 5
• IAJILQKETJEXLJ-UHFFFAOYSA-N Galacturonsaeure Natural products O=CC(O)C(O)C(O)C(O)C(O)=O IAJILQKETJEXLJ-UHFFFAOYSA-N 0.000 description 5
• 239000006146 Roswell Park Memorial Institute medium Substances 0.000 description 5
• 229930182692 Strobilurin Natural products 0.000 description 5
• ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 description 5
• 208000007501 Trichosporonosis Diseases 0.000 description 5
• 230000009471 action Effects 0.000 description 5
• 230000002421 anti-septic effect Effects 0.000 description 5
• 238000013459 approach Methods 0.000 description 5
• 239000011449 brick Substances 0.000 description 5
• 210000002421 cell wall Anatomy 0.000 description 5
• 230000001413 cellular effect Effects 0.000 description 5
• 239000003610 charcoal Substances 0.000 description 5
• 230000001010 compromised effect Effects 0.000 description 5
• 239000010949 copper Substances 0.000 description 5
• 229910052802 copper Inorganic materials 0.000 description 5
• 239000003246 corticosteroid Substances 0.000 description 5
• 238000001804 debridement Methods 0.000 description 5
• 210000004207 dermis Anatomy 0.000 description 5
• 238000013461 design Methods 0.000 description 5
• 238000011161 development Methods 0.000 description 5
• 239000003085 diluting agent Substances 0.000 description 5
• 230000002708 enhancing effect Effects 0.000 description 5
• 239000007943 implant Substances 0.000 description 5
• 238000001727 in vivo Methods 0.000 description 5
• 235000015097 nutrients Nutrition 0.000 description 5
• 239000002674 ointment Substances 0.000 description 5
• 230000001717 pathogenic effect Effects 0.000 description 5
• 239000012071 phase Substances 0.000 description 5
• 229920001282 polysaccharide Polymers 0.000 description 5
• 239000005017 polysaccharide Substances 0.000 description 5
• 150000004804 polysaccharides Chemical class 0.000 description 5
• 238000011321 prophylaxis Methods 0.000 description 5
• 239000004575 stone Substances 0.000 description 5
• 239000000126 substance Substances 0.000 description 5
• 239000000606 toothpaste Substances 0.000 description 5
• 235000013311 vegetables Nutrition 0.000 description 5
• VVJKKWFAADXIJK-UHFFFAOYSA-N Allylamine Chemical compound NCC=C VVJKKWFAADXIJK-UHFFFAOYSA-N 0.000 description 4
• 208000001961 Alternariosis Diseases 0.000 description 4
• 241000589151 Azotobacter Species 0.000 description 4
• 229930186147 Cephalosporin Natural products 0.000 description 4
• 229920000742 Cotton Polymers 0.000 description 4
• 206010011409 Cross infection Diseases 0.000 description 4
• 108010049047 Echinocandins Proteins 0.000 description 4
• LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 4
• 201000003950 Geotrichosis Diseases 0.000 description 4
• 244000299507 Gossypium hirsutum Species 0.000 description 4
• 229930195098 Hamycin Natural products 0.000 description 4
• 201000002563 Histoplasmosis Diseases 0.000 description 4
• 201000009906 Meningitis Diseases 0.000 description 4
• 241000589540 Pseudomonas fluorescens Species 0.000 description 4
• 206010041736 Sporotrichosis Diseases 0.000 description 4
• 241000223238 Trichophyton Species 0.000 description 4
• 241000223230 Trichosporon Species 0.000 description 4
• 241000222126 [Candida] glabrata Species 0.000 description 4
• 239000000443 aerosol Substances 0.000 description 4
• FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 4
• 229940088710 antibiotic agent Drugs 0.000 description 4
• 229940064004 antiseptic throat preparations Drugs 0.000 description 4
• 201000010564 basidiobolomycosis Diseases 0.000 description 4
• AEMOLEFTQBMNLQ-UHFFFAOYSA-N beta-D-galactopyranuronic acid Natural products OC1OC(C(O)=O)C(O)C(O)C1O AEMOLEFTQBMNLQ-UHFFFAOYSA-N 0.000 description 4
• 229940124630 bronchodilator Drugs 0.000 description 4
• 208000032343 candida glabrata infection Diseases 0.000 description 4
• 229940124587 cephalosporin Drugs 0.000 description 4
• 150000001780 cephalosporins Chemical class 0.000 description 4
• 235000013339 cereals Nutrition 0.000 description 4
• 239000003638 chemical reducing agent Substances 0.000 description 4
• 201000010563 conidiobolomycosis Diseases 0.000 description 4
• 239000000975 dye Substances 0.000 description 4
• 230000007613 environmental effect Effects 0.000 description 4
• 238000006345 epimerization reaction Methods 0.000 description 4
• 230000004890 epithelial barrier function Effects 0.000 description 4
• 239000006260 foam Substances 0.000 description 4
• BPZSYCZIITTYBL-UHFFFAOYSA-N formoterol Chemical compound C1=CC(OC)=CC=C1CC(C)NCC(O)C1=CC=C(O)C(NC=O)=C1 BPZSYCZIITTYBL-UHFFFAOYSA-N 0.000 description 4
• 229960002848 formoterol Drugs 0.000 description 4
• 208000024386 fungal infectious disease Diseases 0.000 description 4
• 229950006942 hamycin Drugs 0.000 description 4
• 230000003308 immunostimulating effect Effects 0.000 description 4
• 230000006872 improvement Effects 0.000 description 4
• 229960001361 ipratropium bromide Drugs 0.000 description 4
• 210000003734 kidney Anatomy 0.000 description 4
• 210000004185 liver Anatomy 0.000 description 4
• 239000011159 matrix material Substances 0.000 description 4
• 239000002324 mouth wash Substances 0.000 description 4
• 108020004707 nucleic acids Proteins 0.000 description 4
• 102000039446 nucleic acids Human genes 0.000 description 4
• 150000007523 nucleic acids Chemical class 0.000 description 4
• 239000003973 paint Substances 0.000 description 4
• 239000000123 paper Substances 0.000 description 4
• 229960005205 prednisolone Drugs 0.000 description 4
• OIGNJSKKLXVSLS-VWUMJDOOSA-N prednisolone Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OIGNJSKKLXVSLS-VWUMJDOOSA-N 0.000 description 4
• 230000008569 process Effects 0.000 description 4
• 230000004044 response Effects 0.000 description 4
• 238000013207 serial dilution Methods 0.000 description 4
• 230000002485 urinary effect Effects 0.000 description 4
• 239000002966 varnish Substances 0.000 description 4
• XMAYWYJOQHXEEK-OZXSUGGESA-N (2R,4S)-ketoconazole Chemical compound C1CN(C(=O)C)CCN1C(C=C1)=CC=C1OC[C@@H]1O[C@@](CN2C=NC=C2)(C=2C(=CC(Cl)=CC=2)Cl)OC1 XMAYWYJOQHXEEK-OZXSUGGESA-N 0.000 description 3
• MQHLMHIZUIDKOO-OKZBNKHCSA-N (2R,6S)-2,6-dimethyl-4-[(2S)-2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine Chemical compound C1=CC(C(C)(C)CC)=CC=C1C[C@H](C)CN1C[C@@H](C)O[C@@H](C)C1 MQHLMHIZUIDKOO-OKZBNKHCSA-N 0.000 description 3
• AFNXATANNDIXLG-SFHVURJKSA-N 1-[(2r)-2-[(4-chlorophenyl)methylsulfanyl]-2-(2,4-dichlorophenyl)ethyl]imidazole Chemical compound C1=CC(Cl)=CC=C1CS[C@H](C=1C(=CC(Cl)=CC=1)Cl)CN1C=NC=C1 AFNXATANNDIXLG-SFHVURJKSA-N 0.000 description 3
• 241000251468 Actinopterygii Species 0.000 description 3
• 239000005736 Benthiavalicarb Substances 0.000 description 3
• 206010006802 Burns second degree Diseases 0.000 description 3
• 241000144583 Candida dubliniensis Species 0.000 description 3
• 241001672694 Citrus reticulata Species 0.000 description 3
• 241000222175 Diutina rugosa Species 0.000 description 3
• 206010015150 Erythema Diseases 0.000 description 3
• 241000223195 Fusarium graminearum Species 0.000 description 3
• 241000223221 Fusarium oxysporum Species 0.000 description 3
• 241000619295 Fusarium solani species complex Species 0.000 description 3
• 241000282412 Homo Species 0.000 description 3
• 240000005979 Hordeum vulgare Species 0.000 description 3
• 235000007340 Hordeum vulgare Nutrition 0.000 description 3
• 206010020751 Hypersensitivity Diseases 0.000 description 3
• 240000007049 Juglans regia Species 0.000 description 3
• 235000009496 Juglans regia Nutrition 0.000 description 3
• 241000144128 Lichtheimia corymbifera Species 0.000 description 3
• 241000908234 Mucor indicus Species 0.000 description 3
• 208000010195 Onychomycosis Diseases 0.000 description 3
• 240000007594 Oryza sativa Species 0.000 description 3
• 235000007164 Oryza sativa Nutrition 0.000 description 3
• 241000228143 Penicillium Species 0.000 description 3
• 239000004698 Polyethylene Substances 0.000 description 3
• DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
• 241001465752 Purpureocillium lilacinum Species 0.000 description 3
• 239000005869 Pyraclostrobin Substances 0.000 description 3
• 239000012979 RPMI medium Substances 0.000 description 3
• 240000005384 Rhizopus oryzae Species 0.000 description 3
• 235000013752 Rhizopus oryzae Nutrition 0.000 description 3
• 240000004808 Saccharomyces cerevisiae Species 0.000 description 3
• 235000014680 Saccharomyces cerevisiae Nutrition 0.000 description 3
• 241000190542 Sarocladium kiliense Species 0.000 description 3
• 241000228417 Sarocladium strictum Species 0.000 description 3
• 241000132889 Scedosporium Species 0.000 description 3
• VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 3
• 241000857613 Ticida Species 0.000 description 3
• 201000010618 Tinea cruris Diseases 0.000 description 3
• 240000008042 Zea mays Species 0.000 description 3
• 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 3
• 235000002017 Zea mays subsp mays Nutrition 0.000 description 3
• 230000001133 acceleration Effects 0.000 description 3
• 238000005903 acid hydrolysis reaction Methods 0.000 description 3
• 239000000654 additive Substances 0.000 description 3
• 235000019169 all-trans-retinol Nutrition 0.000 description 3
• 229960003204 amorolfine Drugs 0.000 description 3
• 201000003465 angular cheilitis Diseases 0.000 description 3
• 125000000129 anionic group Chemical group 0.000 description 3
• 239000002260 anti-inflammatory agent Substances 0.000 description 3
• 239000003443 antiviral agent Substances 0.000 description 3
• 239000011324 bead Substances 0.000 description 3
• VVSLYIKSEBPRSN-PELKAZGASA-N benthiavalicarb Chemical compound C1=C(F)C=C2SC([C@@H](C)NC(=O)[C@@H](NC(O)=O)C(C)C)=NC2=C1 VVSLYIKSEBPRSN-PELKAZGASA-N 0.000 description 3
• 238000004166 bioassay Methods 0.000 description 3
• 230000002599 biostatic effect Effects 0.000 description 3
• 229960002962 butenafine Drugs 0.000 description 3
• ABJKWBDEJIDSJZ-UHFFFAOYSA-N butenafine Chemical compound C=1C=CC2=CC=CC=C2C=1CN(C)CC1=CC=C(C(C)(C)C)C=C1 ABJKWBDEJIDSJZ-UHFFFAOYSA-N 0.000 description 3
• PTOJXIKSKSASRB-UHFFFAOYSA-O candicine Chemical compound C[N+](C)(C)CCC1=CC=C(O)C=C1 PTOJXIKSKSASRB-UHFFFAOYSA-O 0.000 description 3
• 239000002775 capsule Substances 0.000 description 3
• DKVNPHBNOWQYFE-UHFFFAOYSA-N carbamodithioic acid Chemical compound NC(S)=S DKVNPHBNOWQYFE-UHFFFAOYSA-N 0.000 description 3
• 230000030833 cell death Effects 0.000 description 3
• 239000000919 ceramic Substances 0.000 description 3
• 208000007287 cheilitis Diseases 0.000 description 3
• 238000003776 cleavage reaction Methods 0.000 description 3
• 229960004022 clotrimazole Drugs 0.000 description 3
• VNFPBHJOKIVQEB-UHFFFAOYSA-N clotrimazole Chemical compound ClC1=CC=CC=C1C(N1C=NC=C1)(C=1C=CC=CC=1)C1=CC=CC=C1 VNFPBHJOKIVQEB-UHFFFAOYSA-N 0.000 description 3
• 239000000470 constituent Substances 0.000 description 3
• 235000005822 corn Nutrition 0.000 description 3
• 230000003111 delayed effect Effects 0.000 description 3
• 230000006866 deterioration Effects 0.000 description 3
• 238000010790 dilution Methods 0.000 description 3
• 239000012895 dilution Substances 0.000 description 3
• ZUOUZKKEUPVFJK-UHFFFAOYSA-N diphenyl Chemical compound C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 description 3
• 239000012990 dithiocarbamate Substances 0.000 description 3
• 230000008497 endothelial barrier function Effects 0.000 description 3
• 235000019688 fish Nutrition 0.000 description 3
• 239000007789 gas Substances 0.000 description 3
• 239000001963 growth medium Substances 0.000 description 3
• 210000002216 heart Anatomy 0.000 description 3
• 229920001519 homopolymer Polymers 0.000 description 3
• 239000003022 immunostimulating agent Substances 0.000 description 3
• 230000002757 inflammatory effect Effects 0.000 description 3
• 230000005764 inhibitory process Effects 0.000 description 3
• 238000011081 inoculation Methods 0.000 description 3
• 239000002054 inoculum Substances 0.000 description 3
• 229960004125 ketoconazole Drugs 0.000 description 3
• 230000000670 limiting effect Effects 0.000 description 3
• 229960003255 natamycin Drugs 0.000 description 3
• 235000010298 natamycin Nutrition 0.000 description 3
• 239000004311 natamycin Substances 0.000 description 3
• NCXMLFZGDNKEPB-FFPOYIOWSA-N natamycin Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/C[C@@H](C)OC(=O)/C=C/[C@H]2O[C@@H]2C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 NCXMLFZGDNKEPB-FFPOYIOWSA-N 0.000 description 3
• 230000001338 necrotic effect Effects 0.000 description 3
• 230000003287 optical effect Effects 0.000 description 3
• 230000036961 partial effect Effects 0.000 description 3
• 239000000575 pesticide Substances 0.000 description 3
• 244000000003 plant pathogen Species 0.000 description 3
• 231100000572 poisoning Toxicity 0.000 description 3
• 230000000607 poisoning effect Effects 0.000 description 3
• 229920000573 polyethylene Polymers 0.000 description 3
• 239000005077 polysulfide Substances 0.000 description 3
• 229920001021 polysulfide Polymers 0.000 description 3
• 150000008117 polysulfides Polymers 0.000 description 3
• 229910052573 porcelain Inorganic materials 0.000 description 3
• 239000011148 porous material Substances 0.000 description 3
• 239000003755 preservative agent Substances 0.000 description 3
• 230000003449 preventive effect Effects 0.000 description 3
• 235000018102 proteins Nutrition 0.000 description 3
• 102000004169 proteins and genes Human genes 0.000 description 3
• HZRSNVGNWUDEFX-UHFFFAOYSA-N pyraclostrobin Chemical compound COC(=O)N(OC)C1=CC=CC=C1COC1=NN(C=2C=CC(Cl)=CC=2)C=C1 HZRSNVGNWUDEFX-UHFFFAOYSA-N 0.000 description 3
• 235000009566 rice Nutrition 0.000 description 3
• 230000007017 scission Effects 0.000 description 3
• 239000002453 shampoo Substances 0.000 description 3
• 239000000344 soap Substances 0.000 description 3
• 239000011734 sodium Substances 0.000 description 3
• 229960002607 sulconazole Drugs 0.000 description 3
• 239000006188 syrup Substances 0.000 description 3
• 235000020357 syrup Nutrition 0.000 description 3
• 210000001138 tear Anatomy 0.000 description 3
• 201000004647 tinea pedis Diseases 0.000 description 3
• 201000005882 tinea unguium Diseases 0.000 description 3
• 229940034610 toothpaste Drugs 0.000 description 3
• 230000000699 topical effect Effects 0.000 description 3
• 239000003053 toxin Substances 0.000 description 3
• 235000020234 walnut Nutrition 0.000 description 3
• BLSQLHNBWJLIBQ-OZXSUGGESA-N (2R,4S)-terconazole Chemical compound C1CN(C(C)C)CCN1C(C=C1)=CC=C1OC[C@@H]1O[C@@](CN2N=CN=C2)(C=2C(=CC(Cl)=CC=2)Cl)OC1 BLSQLHNBWJLIBQ-OZXSUGGESA-N 0.000 description 2
• MPIPASJGOJYODL-SFHVURJKSA-N (R)-isoconazole Chemical compound ClC1=CC(Cl)=CC=C1[C@@H](OCC=1C(=CC=CC=1Cl)Cl)CN1C=NC=C1 MPIPASJGOJYODL-SFHVURJKSA-N 0.000 description 2
• RATSWNOMCHFQGJ-TUYNVFRMSA-N (e)-but-2-enedioic acid;n-[2-hydroxy-5-[(1s)-1-hydroxy-2-[[(2s)-1-(4-methoxyphenyl)propan-2-yl]amino]ethyl]phenyl]formamide;dihydrate Chemical compound O.O.OC(=O)\C=C\C(O)=O.C1=CC(OC)=CC=C1C[C@H](C)NC[C@@H](O)C1=CC=C(O)C(NC=O)=C1.C1=CC(OC)=CC=C1C[C@H](C)NC[C@@H](O)C1=CC=C(O)C(NC=O)=C1 RATSWNOMCHFQGJ-TUYNVFRMSA-N 0.000 description 2
• FXVNBZGTAWLLNE-UHFFFAOYSA-N 1,3-thiazole;zinc Chemical compound [Zn].C1=CSC=N1 FXVNBZGTAWLLNE-UHFFFAOYSA-N 0.000 description 2
• AZQWKYJCGOJGHM-UHFFFAOYSA-N 1,4-benzoquinone Chemical compound O=C1C=CC(=O)C=C1 AZQWKYJCGOJGHM-UHFFFAOYSA-N 0.000 description 2
• NCJRWSQYSLEKEI-UHFFFAOYSA-N 1-(1,3-benzothiazol-2-yl)-3-propan-2-ylurea Chemical compound C1=CC=C2SC(NC(=O)NC(C)C)=NC2=C1 NCJRWSQYSLEKEI-UHFFFAOYSA-N 0.000 description 2
• ZCJYUTQZBAIHBS-UHFFFAOYSA-N 1-[2-(2,4-dichlorophenyl)-2-{[4-(phenylsulfanyl)benzyl]oxy}ethyl]imidazole Chemical compound ClC1=CC(Cl)=CC=C1C(OCC=1C=CC(SC=2C=CC=CC=2)=CC=1)CN1C=NC=C1 ZCJYUTQZBAIHBS-UHFFFAOYSA-N 0.000 description 2
• INJPEINGXBVKEB-RTBURBONSA-N 1-[[(2r,3r)-3-[(2,6-difluorophenyl)methoxy]-5-fluoro-2,3-dihydro-1-benzothiophen-2-yl]methyl]imidazole Chemical compound C([C@H]1SC2=CC=C(C=C2[C@H]1OCC=1C(=CC=CC=1F)F)F)N1C=CN=C1 INJPEINGXBVKEB-RTBURBONSA-N 0.000 description 2
• ULCWZQJLFZEXCS-UHFFFAOYSA-N 1-[[2-(2,4-dichlorophenyl)-5-(2,2,2-trifluoroethoxy)oxolan-2-yl]methyl]-1,2,4-triazole Chemical compound O1C(OCC(F)(F)F)CCC1(C=1C(=CC(Cl)=CC=1)Cl)CN1N=CN=C1 ULCWZQJLFZEXCS-UHFFFAOYSA-N 0.000 description 2
• OCAPBUJLXMYKEJ-UHFFFAOYSA-N 1-[biphenyl-4-yl(phenyl)methyl]imidazole Chemical compound C1=NC=CN1C(C=1C=CC(=CC=1)C=1C=CC=CC=1)C1=CC=CC=C1 OCAPBUJLXMYKEJ-UHFFFAOYSA-N 0.000 description 2
• OICGFSUWXCJLCO-UHFFFAOYSA-N 1-ethylsulfonylsulfanylethane Chemical compound CCSS(=O)(=O)CC OICGFSUWXCJLCO-UHFFFAOYSA-N 0.000 description 2
• LEZWWPYKPKIXLL-UHFFFAOYSA-N 1-{2-(4-chlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl}imidazole Chemical compound C1=CC(Cl)=CC=C1COC(C=1C(=CC(Cl)=CC=1)Cl)CN1C=NC=C1 LEZWWPYKPKIXLL-UHFFFAOYSA-N 0.000 description 2
• JLGKQTAYUIMGRK-UHFFFAOYSA-N 1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}imidazole Chemical compound ClC1=CC(Cl)=CC=C1C(OCC=1C2=CC=CC(Cl)=C2SC=1)CN1C=NC=C1 JLGKQTAYUIMGRK-UHFFFAOYSA-N 0.000 description 2
• HYZJCKYKOHLVJF-UHFFFAOYSA-N 1H-benzimidazole Chemical compound C1=CC=C2NC=NC2=C1 HYZJCKYKOHLVJF-UHFFFAOYSA-N 0.000 description 2
• DNBMPXLFKQCOBV-UHFFFAOYSA-N 2-(2-ethoxyethoxy)ethyl n-(1h-benzimidazol-2-yl)carbamate Chemical compound C1=CC=C2NC(NC(=O)OCCOCCOCC)=NC2=C1 DNBMPXLFKQCOBV-UHFFFAOYSA-N 0.000 description 2
• RUGYNGIMTAFTLP-UHFFFAOYSA-N 2-(3,5-dimethylpyrazol-1-yl)-1h-benzimidazole Chemical compound N1=C(C)C=C(C)N1C1=NC2=CC=CC=C2N1 RUGYNGIMTAFTLP-UHFFFAOYSA-N 0.000 description 2
• FSKNXCHJIFBRBT-UHFFFAOYSA-N 2-[2-[2-(dodecylamino)ethylamino]ethylamino]acetic acid Chemical compound CCCCCCCCCCCCNCCNCCNCC(O)=O FSKNXCHJIFBRBT-UHFFFAOYSA-N 0.000 description 2
• WNZQDUSMALZDQF-UHFFFAOYSA-N 2-benzofuran-1(3H)-one Chemical compound C1=CC=C2C(=O)OCC2=C1 WNZQDUSMALZDQF-UHFFFAOYSA-N 0.000 description 2
• QTWJRLJHJPIABL-UHFFFAOYSA-N 2-methylphenol;3-methylphenol;4-methylphenol Chemical compound CC1=CC=C(O)C=C1.CC1=CC=CC(O)=C1.CC1=CC=CC=C1O QTWJRLJHJPIABL-UHFFFAOYSA-N 0.000 description 2
• GPUHJQHXIFJPGN-UHFFFAOYSA-N 3-(3,5-dichlorophenyl)-1-(3-methylbutanoyl)imidazolidine-2,4-dione Chemical compound O=C1N(C(=O)CC(C)C)CC(=O)N1C1=CC(Cl)=CC(Cl)=C1 GPUHJQHXIFJPGN-UHFFFAOYSA-N 0.000 description 2
• FSCWZHGZWWDELK-UHFFFAOYSA-N 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione Chemical compound O=C1C(C)(C=C)OC(=O)N1C1=CC(Cl)=CC(Cl)=C1 FSCWZHGZWWDELK-UHFFFAOYSA-N 0.000 description 2
• XTDZGXBTXBEZDN-UHFFFAOYSA-N 3-(difluoromethyl)-N-(9-isopropyl-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl)-1-methylpyrazole-4-carboxamide Chemical compound CC(C)C1C2CCC1C1=C2C=CC=C1NC(=O)C1=CN(C)N=C1C(F)F XTDZGXBTXBEZDN-UHFFFAOYSA-N 0.000 description 2
• NRTLIYOWLVMQBO-UHFFFAOYSA-N 5-chloro-1,3-dimethyl-N-(1,1,3-trimethyl-1,3-dihydro-2-benzofuran-4-yl)pyrazole-4-carboxamide Chemical compound C=12C(C)OC(C)(C)C2=CC=CC=1NC(=O)C=1C(C)=NN(C)C=1Cl NRTLIYOWLVMQBO-UHFFFAOYSA-N 0.000 description 2
• PCCSBWNGDMYFCW-UHFFFAOYSA-N 5-methyl-5-(4-phenoxyphenyl)-3-(phenylamino)-1,3-oxazolidine-2,4-dione Chemical compound O=C1C(C)(C=2C=CC(OC=3C=CC=CC=3)=CC=2)OC(=O)N1NC1=CC=CC=C1 PCCSBWNGDMYFCW-UHFFFAOYSA-N 0.000 description 2
• 241000235389 Absidia Species 0.000 description 2
• 241001019659 Acremonium <Plectosphaerellaceae> Species 0.000 description 2
• 102100032381 Alpha-hemoglobin-stabilizing protein Human genes 0.000 description 2
• 101710198436 Alpha-hemoglobin-stabilizing protein Proteins 0.000 description 2
• 241000223602 Alternaria alternata Species 0.000 description 2
• 241000266416 Alternaria japonica Species 0.000 description 2
• 239000005727 Amisulbrom Substances 0.000 description 2
• 108010064760 Anidulafungin Proteins 0.000 description 2
• 241000272517 Anseriformes Species 0.000 description 2
• 241000203069 Archaea Species 0.000 description 2
• 201000002909 Aspergillosis Diseases 0.000 description 2
• 241000228193 Aspergillus clavatus Species 0.000 description 2
• 208000036641 Aspergillus infections Diseases 0.000 description 2
• 241000122824 Aspergillus ochraceus Species 0.000 description 2
• 235000007319 Avena orientalis Nutrition 0.000 description 2
• 244000075850 Avena orientalis Species 0.000 description 2
• 239000005730 Azoxystrobin Substances 0.000 description 2
• 235000017166 Bambusa arundinacea Nutrition 0.000 description 2
• 235000017491 Bambusa tulda Nutrition 0.000 description 2
• 239000005734 Benalaxyl Substances 0.000 description 2
• 239000005735 Benalaxyl-M Substances 0.000 description 2
• KXDAEFPNCMNJSK-UHFFFAOYSA-N Benzamide Chemical compound NC(=O)C1=CC=CC=C1 KXDAEFPNCMNJSK-UHFFFAOYSA-N 0.000 description 2
• 206010005913 Body tinea Diseases 0.000 description 2
• 239000005740 Boscalid Substances 0.000 description 2
• 235000011299 Brassica oleracea var botrytis Nutrition 0.000 description 2
• 240000003259 Brassica oleracea var. botrytis Species 0.000 description 2
• 206010006797 Burns first degree Diseases 0.000 description 2
• 206010006803 Burns third degree Diseases 0.000 description 2
• KAKZBPTYRLMSJV-UHFFFAOYSA-N Butadiene Chemical compound C=CC=C KAKZBPTYRLMSJV-UHFFFAOYSA-N 0.000 description 2
• CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
• 239000005746 Carboxin Substances 0.000 description 2
• 108010020326 Caspofungin Proteins 0.000 description 2
• 241000700198 Cavia Species 0.000 description 2
• 229920002101 Chitin Polymers 0.000 description 2
• KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 description 2
• 206010008803 Chromoblastomycosis Diseases 0.000 description 2
• 208000015116 Chromomycosis Diseases 0.000 description 2
• 241000222290 Cladosporium Species 0.000 description 2
• 241000221751 Claviceps purpurea Species 0.000 description 2
• 206010010356 Congenital anomaly Diseases 0.000 description 2
• RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 2
• JJLJMEJHUUYSSY-UHFFFAOYSA-L Copper hydroxide Chemical compound [OH-].[OH-].[Cu+2] JJLJMEJHUUYSSY-UHFFFAOYSA-L 0.000 description 2
• 239000005750 Copper hydroxide Substances 0.000 description 2
• 241001522864 Cryptococcus gattii VGI Species 0.000 description 2
• 241000223233 Cutaneotrichosporon cutaneum Species 0.000 description 2
• 206010011676 Cutaneous sporotrichosis Diseases 0.000 description 2
• MKZGVGOBXZJKGV-UHFFFAOYSA-N Cypendazole Chemical compound C1=CC=C2N(C(=O)NCCCCCC#N)C(NC(=O)OC)=NC2=C1 MKZGVGOBXZJKGV-UHFFFAOYSA-N 0.000 description 2
• FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 2
• 102000007260 Deoxyribonuclease I Human genes 0.000 description 2
• 108010008532 Deoxyribonuclease I Proteins 0.000 description 2
• 206010012504 Dermatophytosis Diseases 0.000 description 2
• MDNWOSOZYLHTCG-UHFFFAOYSA-N Dichlorophen Chemical compound OC1=CC=C(Cl)C=C1CC1=CC(Cl)=CC=C1O MDNWOSOZYLHTCG-UHFFFAOYSA-N 0.000 description 2
• ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 description 2
• 206010051814 Eschar Diseases 0.000 description 2
• 239000005772 Famoxadone Substances 0.000 description 2
• IWDQPCIQCXRBQP-UHFFFAOYSA-M Fenaminosulf Chemical compound [Na+].CN(C)C1=CC=C(N=NS([O-])(=O)=O)C=C1 IWDQPCIQCXRBQP-UHFFFAOYSA-M 0.000 description 2
• 239000005782 Fluopicolide Substances 0.000 description 2
• 239000005783 Fluopyram Substances 0.000 description 2
• GHJWNRRCRIGGIO-UHFFFAOYSA-N Fosfluconazole Chemical compound C1=NC=NN1CC(C=1C(=CC(F)=CC=1)F)(OP(O)(=O)O)CN1C=NC=N1 GHJWNRRCRIGGIO-UHFFFAOYSA-N 0.000 description 2
• 235000016623 Fragaria vesca Nutrition 0.000 description 2
• 240000009088 Fragaria x ananassa Species 0.000 description 2
• 235000011363 Fragaria x ananassa Nutrition 0.000 description 2
• 241000122692 Fusarium avenaceum Species 0.000 description 2
• 241000223194 Fusarium culmorum Species 0.000 description 2
• 241001489200 Fusarium poae Species 0.000 description 2
• 241000690372 Fusarium proliferatum Species 0.000 description 2
• 241000233732 Fusarium verticillioides Species 0.000 description 2
• 108010010803 Gelatin Proteins 0.000 description 2
• 235000010469 Glycine max Nutrition 0.000 description 2
• 102100027377 HBS1-like protein Human genes 0.000 description 2
• 101710197631 HBS1-like protein Proteins 0.000 description 2
• 101000988834 Homo sapiens Hypoxanthine-guanine phosphoribosyltransferase Proteins 0.000 description 2
• 101000973623 Homo sapiens Neuronal growth regulator 1 Proteins 0.000 description 2
• MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
• 102100029098 Hypoxanthine-guanine phosphoribosyltransferase Human genes 0.000 description 2
• 208000031880 Intertrigo candida Diseases 0.000 description 2
• 208000037026 Invasive Fungal Infections Diseases 0.000 description 2
• 239000005867 Iprodione Substances 0.000 description 2
• 239000005797 Iprovalicarb Substances 0.000 description 2
• XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
• 239000005799 Isopyrazam Substances 0.000 description 2
• NWUWYYSKZYIQAE-ZBFHGGJFSA-N L-(R)-iprovalicarb Chemical compound CC(C)OC(=O)N[C@@H](C(C)C)C(=O)N[C@H](C)C1=CC=C(C)C=C1 NWUWYYSKZYIQAE-ZBFHGGJFSA-N 0.000 description 2
• 241001466453 Laminaria Species 0.000 description 2
• 241000132887 Lomentospora prolificans Species 0.000 description 2
• 241001344131 Magnaporthe grisea Species 0.000 description 2
• 241000555688 Malassezia furfur Species 0.000 description 2
• 241001299738 Malassezia pachydermatis Species 0.000 description 2
• 239000005802 Mancozeb Substances 0.000 description 2
• 229930195725 Mannitol Natural products 0.000 description 2
• 239000005807 Metalaxyl Substances 0.000 description 2
• 239000005808 Metalaxyl-M Substances 0.000 description 2
• 239000005809 Metiram Substances 0.000 description 2
• UDSJPFPDKCMYBD-UHFFFAOYSA-N Metsulfovax Chemical compound S1C(C)=NC(C)=C1C(=O)NC1=CC=CC=C1 UDSJPFPDKCMYBD-UHFFFAOYSA-N 0.000 description 2
• 108010021062 Micafungin Proteins 0.000 description 2
• 201000000090 Microsporidiosis Diseases 0.000 description 2
• 241001460074 Microsporum distortum Species 0.000 description 2
• 241000228347 Monascus <ascomycete fungus> Species 0.000 description 2
• YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 description 2
• 241000235395 Mucor Species 0.000 description 2
• 241001378740 Mugil liza Species 0.000 description 2
• 240000005561 Musa balbisiana Species 0.000 description 2
• 241000041810 Mycetoma Species 0.000 description 2
• NQRFDNJEBWAUBL-UHFFFAOYSA-N N-[cyano(2-thienyl)methyl]-4-ethyl-2-(ethylamino)-1,3-thiazole-5-carboxamide Chemical compound S1C(NCC)=NC(CC)=C1C(=O)NC(C#N)C1=CC=CS1 NQRFDNJEBWAUBL-UHFFFAOYSA-N 0.000 description 2
• 241001443590 Naganishia albida Species 0.000 description 2
• 241000760367 Neocallimastigomycetes Species 0.000 description 2
• 102100022223 Neuronal growth regulator 1 Human genes 0.000 description 2
• MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 description 2
• 206010029803 Nosocomial infection Diseases 0.000 description 2
• 241001236817 Paecilomyces <Clavicipitaceae> Species 0.000 description 2
• 241000222051 Papiliotrema laurentii Species 0.000 description 2
• 206010033767 Paracoccidioides infections Diseases 0.000 description 2
• 201000000301 Paracoccidioidomycosis Diseases 0.000 description 2
• 206010034016 Paronychia Diseases 0.000 description 2
• 241000029132 Paronychia Species 0.000 description 2
• ZRWPUFFVAOMMNM-UHFFFAOYSA-N Patulin Chemical compound OC1OCC=C2OC(=O)C=C12 ZRWPUFFVAOMMNM-UHFFFAOYSA-N 0.000 description 2
• 241001494479 Pecora Species 0.000 description 2
• JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 description 2
• 206010064458 Penicilliosis Diseases 0.000 description 2
• 241001123663 Penicillium expansum Species 0.000 description 2
• 102000035195 Peptidases Human genes 0.000 description 2
• 108091005804 Peptidases Proteins 0.000 description 2
• 239000001888 Peptone Substances 0.000 description 2
• 108010080698 Peptones Proteins 0.000 description 2
• 208000037581 Persistent Infection Diseases 0.000 description 2
• 244000082204 Phyllostachys viridis Species 0.000 description 2
• 235000015334 Phyllostachys viridis Nutrition 0.000 description 2
• 235000008331 Pinus X rigitaeda Nutrition 0.000 description 2
• 241000018646 Pinus brutia Species 0.000 description 2
• 235000011613 Pinus brutia Nutrition 0.000 description 2
• 208000005384 Pneumocystis Pneumonia Diseases 0.000 description 2
• 206010073755 Pneumocystis jirovecii pneumonia Diseases 0.000 description 2
• 208000000474 Poliomyelitis Diseases 0.000 description 2
• 239000005823 Propineb Substances 0.000 description 2
• 239000004365 Protease Substances 0.000 description 2
• 241000589517 Pseudomonas aeruginosa Species 0.000 description 2
• 241000221301 Puccinia graminis Species 0.000 description 2
• JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 2
• 235000014443 Pyrus communis Nutrition 0.000 description 2
• 241000219492 Quercus Species 0.000 description 2
• 235000016976 Quercus macrolepis Nutrition 0.000 description 2
• SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 description 2
• 208000004364 Rhinosporidiosis Diseases 0.000 description 2
• 241000235527 Rhizopus Species 0.000 description 2
• 241000235546 Rhizopus stolonifer Species 0.000 description 2
• 244000281247 Ribes rubrum Species 0.000 description 2
• 235000016911 Ribes sativum Nutrition 0.000 description 2
• AWGBZRVEGDNLDZ-UHFFFAOYSA-N Rimocidin Natural products C1C(C(C(O)C2)C(O)=O)OC2(O)CC(O)CCCC(=O)CC(O)C(CC)C(=O)OC(CCC)CC=CC=CC=CC=CC1OC1OC(C)C(O)C(N)C1O AWGBZRVEGDNLDZ-UHFFFAOYSA-N 0.000 description 2
• AWGBZRVEGDNLDZ-JCUCCFEFSA-N Rimocidine Chemical compound O([C@H]1/C=C/C=C/C=C/C=C/C[C@H](OC(=O)[C@@H](CC)[C@H](O)CC(=O)CCC[C@H](O)C[C@@]2(O)O[C@H]([C@@H]([C@@H](O)C2)C(O)=O)C1)CCC)[C@@H]1O[C@H](C)[C@@H](O)[C@H](N)[C@@H]1O AWGBZRVEGDNLDZ-JCUCCFEFSA-N 0.000 description 2
• 239000008156 Ringer's lactate solution Substances 0.000 description 2
• 240000000111 Saccharum officinarum Species 0.000 description 2
• 235000007201 Saccharum officinarum Nutrition 0.000 description 2
• 206010039509 Scab Diseases 0.000 description 2
• 241000223598 Scedosporium boydii Species 0.000 description 2
• 241000978719 Seiridium cardinale Species 0.000 description 2
• PXIPVTKHYLBLMZ-UHFFFAOYSA-N Sodium azide Chemical compound [Na+].[N-]=[N+]=[N-] PXIPVTKHYLBLMZ-UHFFFAOYSA-N 0.000 description 2
• DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 2
• 244000062793 Sorghum vulgare Species 0.000 description 2
• 239000004098 Tetracycline Substances 0.000 description 2
• FZWLAAWBMGSTSO-UHFFFAOYSA-N Thiazole Chemical compound C1=CSC=N1 FZWLAAWBMGSTSO-UHFFFAOYSA-N 0.000 description 2
• 239000005842 Thiophanate-methyl Substances 0.000 description 2
• YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical compound C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 description 2
• 241000130764 Tinea Species 0.000 description 2
• 208000007712 Tinea Versicolor Diseases 0.000 description 2
• 206010043866 Tinea capitis Diseases 0.000 description 2
• 206010067719 Tinea faciei Diseases 0.000 description 2
• 206010067197 Tinea manuum Diseases 0.000 description 2
• 206010043871 Tinea nigra Diseases 0.000 description 2
• 206010056131 Tinea versicolour Diseases 0.000 description 2
• 241000893966 Trichophyton verrucosum Species 0.000 description 2
• XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 description 2
• 235000021307 Triticum Nutrition 0.000 description 2
• 244000098338 Triticum aestivum Species 0.000 description 2
• XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
• 241001474928 Ustilaginoidea virens Species 0.000 description 2
• 241000514371 Ustilago avenae Species 0.000 description 2
• 241000509513 Ustilago hordei Species 0.000 description 2
• 235000015919 Ustilago maydis Nutrition 0.000 description 2
• 244000301083 Ustilago maydis Species 0.000 description 2
• 241000007070 Ustilago nuda Species 0.000 description 2
• 241000233791 Ustilago tritici Species 0.000 description 2
• 240000000851 Vaccinium corymbosum Species 0.000 description 2
• 235000003095 Vaccinium corymbosum Nutrition 0.000 description 2
• 235000017537 Vaccinium myrtillus Nutrition 0.000 description 2
• 241000700605 Viruses Species 0.000 description 2
• 239000005870 Ziram Substances 0.000 description 2
• VQSUKBFBVMSNES-UHFFFAOYSA-K [Cl-].[Cl-].[Cu+].[Cu+].[Cu+].CN(C)C([S-])=S Chemical compound [Cl-].[Cl-].[Cu+].[Cu+].[Cu+].CN(C)C([S-])=S VQSUKBFBVMSNES-UHFFFAOYSA-K 0.000 description 2
• TYBHXIFFPVFXQW-UHFFFAOYSA-N abafungin Chemical compound CC1=CC(C)=CC=C1OC1=CC=CC=C1C1=CSC(NC=2NCCCN=2)=N1 TYBHXIFFPVFXQW-UHFFFAOYSA-N 0.000 description 2
• 229950006373 abafungin Drugs 0.000 description 2
• 150000007513 acids Chemical class 0.000 description 2
• 230000002776 aggregation Effects 0.000 description 2
• 238000004220 aggregation Methods 0.000 description 2
• UHIXWHUVLCAJQL-MPBGBICISA-N albaconazole Chemical compound C([C@@](O)([C@H](N1C(C2=CC=C(Cl)C=C2N=C1)=O)C)C=1C(=CC(F)=CC=1)F)N1C=NC=N1 UHIXWHUVLCAJQL-MPBGBICISA-N 0.000 description 2
• 229950006816 albaconazole Drugs 0.000 description 2
• 229960002669 albendazole Drugs 0.000 description 2
• HXHWSAZORRCQMX-UHFFFAOYSA-N albendazole Chemical compound CCCSC1=CC=C2NC(NC(=O)OC)=NC2=C1 HXHWSAZORRCQMX-UHFFFAOYSA-N 0.000 description 2
• 239000011717 all-trans-retinol Substances 0.000 description 2
• 230000007815 allergy Effects 0.000 description 2
• XXROGKLTLUQVRX-UHFFFAOYSA-N allyl alcohol Chemical compound OCC=C XXROGKLTLUQVRX-UHFFFAOYSA-N 0.000 description 2
• 239000002160 alpha blocker Substances 0.000 description 2
• BREATYVWRHIPIY-UHFFFAOYSA-N amisulbrom Chemical compound CN(C)S(=O)(=O)N1C=NC(S(=O)(=O)N2C3=CC(F)=CC=C3C(Br)=C2C)=N1 BREATYVWRHIPIY-UHFFFAOYSA-N 0.000 description 2
• JHVAMHSQVVQIOT-MFAJLEFUSA-N anidulafungin Chemical compound C1=CC(OCCCCC)=CC=C1C1=CC=C(C=2C=CC(=CC=2)C(=O)N[C@@H]2C(N[C@H](C(=O)N3C[C@H](O)C[C@H]3C(=O)N[C@H](C(=O)N[C@H](C(=O)N3C[C@H](C)[C@H](O)[C@H]3C(=O)N[C@H](O)[C@H](O)C2)[C@@H](C)O)[C@H](O)[C@@H](O)C=2C=CC(O)=CC=2)[C@@H](C)O)=O)C=C1 JHVAMHSQVVQIOT-MFAJLEFUSA-N 0.000 description 2
• 229960003348 anidulafungin Drugs 0.000 description 2
• 210000004102 animal cell Anatomy 0.000 description 2
• 244000037640 animal pathogen Species 0.000 description 2
• 230000000844 anti-bacterial effect Effects 0.000 description 2
• 229940121363 anti-inflammatory agent Drugs 0.000 description 2
• 229940027983 antiseptic and disinfectant quaternary ammonium compound Drugs 0.000 description 2
• 229940121357 antivirals Drugs 0.000 description 2
• 208000002399 aphthous stomatitis Diseases 0.000 description 2
• WFDXOXNFNRHQEC-GHRIWEEISA-N azoxystrobin Chemical compound CO\C=C(\C(=O)OC)C1=CC=CC=C1OC1=CC(OC=2C(=CC=CC=2)C#N)=NC=N1 WFDXOXNFNRHQEC-GHRIWEEISA-N 0.000 description 2
• 230000001580 bacterial effect Effects 0.000 description 2
• 239000011425 bamboo Substances 0.000 description 2
• CJPQIRJHIZUAQP-MRXNPFEDSA-N benalaxyl-M Chemical compound CC=1C=CC=C(C)C=1N([C@H](C)C(=O)OC)C(=O)CC1=CC=CC=C1 CJPQIRJHIZUAQP-MRXNPFEDSA-N 0.000 description 2
• RIOXQFHNBCKOKP-UHFFFAOYSA-N benomyl Chemical compound C1=CC=C2N(C(=O)NCCCC)C(NC(=O)OC)=NC2=C1 RIOXQFHNBCKOKP-UHFFFAOYSA-N 0.000 description 2
• 229960000686 benzalkonium chloride Drugs 0.000 description 2
• IOJUPLGTWVMSFF-UHFFFAOYSA-N benzothiazole Chemical compound C1=CC=C2SC=NC2=C1 IOJUPLGTWVMSFF-UHFFFAOYSA-N 0.000 description 2
• MITFXPHMIHQXPI-UHFFFAOYSA-N benzoxaprofen Natural products N=1C2=CC(C(C(O)=O)C)=CC=C2OC=1C1=CC=C(Cl)C=C1 MITFXPHMIHQXPI-UHFFFAOYSA-N 0.000 description 2
• CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 description 2
• YBHILYKTIRIUTE-UHFFFAOYSA-N berberine Chemical compound C1=C2CC[N+]3=CC4=C(OC)C(OC)=CC=C4C=C3C2=CC2=C1OCO2 YBHILYKTIRIUTE-UHFFFAOYSA-N 0.000 description 2
• 229940093265 berberine Drugs 0.000 description 2
• QISXPYZVZJBNDM-UHFFFAOYSA-N berberine Natural products COc1ccc2C=C3N(Cc2c1OC)C=Cc4cc5OCOc5cc34 QISXPYZVZJBNDM-UHFFFAOYSA-N 0.000 description 2
• 235000021028 berry Nutrition 0.000 description 2
• 229960002206 bifonazole Drugs 0.000 description 2
• 230000004993 binary fission Effects 0.000 description 2
• 229920001222 biopolymer Polymers 0.000 description 2
• 235000010290 biphenyl Nutrition 0.000 description 2
• 239000004305 biphenyl Substances 0.000 description 2
• LLEMOWNGBBNAJR-UHFFFAOYSA-N biphenyl-2-ol Chemical compound OC1=CC=CC=C1C1=CC=CC=C1 LLEMOWNGBBNAJR-UHFFFAOYSA-N 0.000 description 2
• NBNTWDUNCHRWMT-UHFFFAOYSA-N bis(4-chlorophenyl)-pyridin-3-ylmethanol Chemical compound C=1C=C(Cl)C=CC=1C(C=1C=NC=CC=1)(O)C1=CC=C(Cl)C=C1 NBNTWDUNCHRWMT-UHFFFAOYSA-N 0.000 description 2
• LDLMOOXUCMHBMZ-UHFFFAOYSA-N bixafen Chemical compound FC(F)C1=NN(C)C=C1C(=O)NC1=CC=C(F)C=C1C1=CC=C(Cl)C(Cl)=C1 LDLMOOXUCMHBMZ-UHFFFAOYSA-N 0.000 description 2
• 235000021014 blueberries Nutrition 0.000 description 2
• 229940118790 boscalid Drugs 0.000 description 2
• WYEMLYFITZORAB-UHFFFAOYSA-N boscalid Chemical compound C1=CC(Cl)=CC=C1C1=CC=CC=C1NC(=O)C1=CC=CN=C1Cl WYEMLYFITZORAB-UHFFFAOYSA-N 0.000 description 2
• 210000000481 breast Anatomy 0.000 description 2
• GZUXJHMPEANEGY-UHFFFAOYSA-N bromomethane Chemical compound BrC GZUXJHMPEANEGY-UHFFFAOYSA-N 0.000 description 2
• 239000000168 bronchodilator agent Substances 0.000 description 2
• 239000004566 building material Substances 0.000 description 2
• HQABUPZFAYXKJW-UHFFFAOYSA-N butan-1-amine Chemical compound CCCCN HQABUPZFAYXKJW-UHFFFAOYSA-N 0.000 description 2
• 229960005074 butoconazole Drugs 0.000 description 2
• SWLMUYACZKCSHZ-UHFFFAOYSA-N butoconazole Chemical compound C1=CC(Cl)=CC=C1CCC(SC=1C(=CC=CC=1Cl)Cl)CN1C=NC=C1 SWLMUYACZKCSHZ-UHFFFAOYSA-N 0.000 description 2
• 210000001217 buttock Anatomy 0.000 description 2
• TWFZGCMQGLPBSX-UHFFFAOYSA-N carbendazim Chemical compound C1=CC=C2NC(NC(=O)OC)=NC2=C1 TWFZGCMQGLPBSX-UHFFFAOYSA-N 0.000 description 2
• 150000001720 carbohydrates Chemical group 0.000 description 2
• GYSSRZJIHXQEHQ-UHFFFAOYSA-N carboxin Chemical compound S1CCOC(C)=C1C(=O)NC1=CC=CC=C1 GYSSRZJIHXQEHQ-UHFFFAOYSA-N 0.000 description 2
• ULDHMXUKGWMISQ-UHFFFAOYSA-N carvone Chemical compound CC(=C)C1CC=C(C)C(=O)C1 ULDHMXUKGWMISQ-UHFFFAOYSA-N 0.000 description 2
• JYIKNQVWKBUSNH-WVDDFWQHSA-N caspofungin Chemical compound C1([C@H](O)[C@@H](O)[C@H]2C(=O)N[C@H](C(=O)N3CC[C@H](O)[C@H]3C(=O)N[C@H](NCCN)[C@H](O)C[C@@H](C(N[C@H](C(=O)N3C[C@H](O)C[C@H]3C(=O)N2)[C@@H](C)O)=O)NC(=O)CCCCCCCC[C@@H](C)C[C@@H](C)CC)[C@H](O)CCN)=CC=C(O)C=C1 JYIKNQVWKBUSNH-WVDDFWQHSA-N 0.000 description 2
• 229960003034 caspofungin Drugs 0.000 description 2
• 125000002091 cationic group Chemical group 0.000 description 2
• 235000010980 cellulose Nutrition 0.000 description 2
• 229920002678 cellulose Polymers 0.000 description 2
• 239000001913 cellulose Substances 0.000 description 2
• 239000004568 cement Substances 0.000 description 2
• 229940106164 cephalexin Drugs 0.000 description 2
• ZAIPMKNFIOOWCQ-UEKVPHQBSA-N cephalexin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C)C(O)=O)=CC=CC=C1 ZAIPMKNFIOOWCQ-UEKVPHQBSA-N 0.000 description 2
• 239000000460 chlorine Substances 0.000 description 2
• 229910052801 chlorine Inorganic materials 0.000 description 2
• SCKYRAXSEDYPSA-UHFFFAOYSA-N ciclopirox Chemical compound ON1C(=O)C=C(C)C=C1C1CCCCC1 SCKYRAXSEDYPSA-UHFFFAOYSA-N 0.000 description 2
• MYSWGUAQZAJSOK-UHFFFAOYSA-N ciprofloxacin Chemical compound C12=CC(N3CCNCC3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 MYSWGUAQZAJSOK-UHFFFAOYSA-N 0.000 description 2
• 229950002162 cisconazole Drugs 0.000 description 2
• 238000004140 cleaning Methods 0.000 description 2
• 239000013066 combination product Substances 0.000 description 2
• 229940127555 combination product Drugs 0.000 description 2
• 239000004567 concrete Substances 0.000 description 2
• 229910001956 copper hydroxide Inorganic materials 0.000 description 2
• 229910000365 copper sulfate Inorganic materials 0.000 description 2
• ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical compound [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 description 2
• 239000007799 cork Substances 0.000 description 2
• 229960001334 corticosteroids Drugs 0.000 description 2
• 229930003836 cresol Natural products 0.000 description 2
• YPHMISFOHDHNIV-FSZOTQKASA-N cycloheximide Chemical compound C1[C@@H](C)C[C@H](C)C(=O)[C@@H]1[C@H](O)CC1CC(=O)NC(=O)C1 YPHMISFOHDHNIV-FSZOTQKASA-N 0.000 description 2
• 230000007123 defense Effects 0.000 description 2
• WHBIGIKBNXZKFE-UHFFFAOYSA-N delavirdine Chemical compound CC(C)NC1=CC=CN=C1N1CCN(C(=O)C=2NC3=CC=C(NS(C)(=O)=O)C=C3C=2)CC1 WHBIGIKBNXZKFE-UHFFFAOYSA-N 0.000 description 2
• 239000000645 desinfectant Substances 0.000 description 2
• 230000001627 detrimental effect Effects 0.000 description 2
• 239000008121 dextrose Substances 0.000 description 2
• 229960003887 dichlorophen Drugs 0.000 description 2
• PNKGIAQRMACYGQ-UHFFFAOYSA-N dicopper;dizinc;chromium(3+);oxygen(2-) Chemical compound [O-2].[O-2].[O-2].[O-2].[O-2].[O-2].[Cr+3].[Cr+3].[Cu+2].[Cu+2].[Zn+2].[Zn+2] PNKGIAQRMACYGQ-UHFFFAOYSA-N 0.000 description 2
• FBOUIAKEJMZPQG-BLXFFLACSA-N diniconazole-M Chemical compound C1=NC=NN1/C([C@H](O)C(C)(C)C)=C/C1=CC=C(Cl)C=C1Cl FBOUIAKEJMZPQG-BLXFFLACSA-N 0.000 description 2
• DMBHHRLKUKUOEG-UHFFFAOYSA-N diphenylamine Chemical compound C=1C=CC=CC=1NC1=CC=CC=C1 DMBHHRLKUKUOEG-UHFFFAOYSA-N 0.000 description 2
• ZHDBTKPXEJDTTQ-UHFFFAOYSA-N dipyrithione Chemical compound [O-][N+]1=CC=CC=C1SSC1=CC=CC=[N+]1[O-] ZHDBTKPXEJDTTQ-UHFFFAOYSA-N 0.000 description 2
• 231100000676 disease causative agent Toxicity 0.000 description 2
• 238000009826 distribution Methods 0.000 description 2
• NOPFSRXAKWQILS-UHFFFAOYSA-N docosan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCCCO NOPFSRXAKWQILS-UHFFFAOYSA-N 0.000 description 2
• 229940044165 dodicin Drugs 0.000 description 2
• 239000003937 drug carrier Substances 0.000 description 2
• 235000021038 drupes Nutrition 0.000 description 2
• 229960003913 econazole Drugs 0.000 description 2
• 239000003974 emollient agent Substances 0.000 description 2
• 239000000839 emulsion Substances 0.000 description 2
• 230000006862 enzymatic digestion Effects 0.000 description 2
• 230000003628 erosive effect Effects 0.000 description 2
• 231100000321 erythema Toxicity 0.000 description 2
• 231100000333 eschar Toxicity 0.000 description 2
• AEUTYOVWOVBAKS-UWVGGRQHSA-N ethambutol Chemical compound CC[C@@H](CO)NCCN[C@@H](CC)CO AEUTYOVWOVBAKS-UWVGGRQHSA-N 0.000 description 2
• 238000004880 explosion Methods 0.000 description 2
• 229960001274 fenticonazole Drugs 0.000 description 2
• 229960004413 flucytosine Drugs 0.000 description 2
• XRECTZIEBJDKEO-UHFFFAOYSA-N flucytosine Chemical compound NC1=NC(=O)NC=C1F XRECTZIEBJDKEO-UHFFFAOYSA-N 0.000 description 2
• 239000012530 fluid Substances 0.000 description 2
• GBOYJIHYACSLGN-UHFFFAOYSA-N fluopicolide Chemical compound ClC1=CC(C(F)(F)F)=CN=C1CNC(=O)C1=C(Cl)C=CC=C1Cl GBOYJIHYACSLGN-UHFFFAOYSA-N 0.000 description 2
• KVDJTXBXMWJJEF-UHFFFAOYSA-N fluopyram Chemical compound ClC1=CC(C(F)(F)F)=CN=C1CCNC(=O)C1=CC=CC=C1C(F)(F)F KVDJTXBXMWJJEF-UHFFFAOYSA-N 0.000 description 2
• IPENDKRRWFURRE-UHFFFAOYSA-N fluoroimide Chemical compound C1=CC(F)=CC=C1N1C(=O)C(Cl)=C(Cl)C1=O IPENDKRRWFURRE-UHFFFAOYSA-N 0.000 description 2
• 229960003610 formoterol fumarate dihydrate Drugs 0.000 description 2
• 239000012634 fragment Substances 0.000 description 2
• 230000006870 function Effects 0.000 description 2
• 238000004362 fungal culture Methods 0.000 description 2
• HYBBIBNJHNGZAN-UHFFFAOYSA-N furfural Chemical compound O=CC1=CC=CO1 HYBBIBNJHNGZAN-UHFFFAOYSA-N 0.000 description 2
• 230000002496 gastric effect Effects 0.000 description 2
• 239000008273 gelatin Substances 0.000 description 2
• 229920000159 gelatin Polymers 0.000 description 2
• 235000019322 gelatine Nutrition 0.000 description 2
• 235000011852 gelatine desserts Nutrition 0.000 description 2
• 239000011521 glass Substances 0.000 description 2
• 102000006602 glyceraldehyde-3-phosphate dehydrogenase Human genes 0.000 description 2
• 108020004445 glyceraldehyde-3-phosphate dehydrogenase Proteins 0.000 description 2
• 239000011440 grout Substances 0.000 description 2
• 230000009036 growth inhibition Effects 0.000 description 2
• 239000003966 growth inhibitor Substances 0.000 description 2
• 239000008266 hair spray Substances 0.000 description 2
• ACGUYXCXAPNIKK-UHFFFAOYSA-N hexachlorophene Chemical compound OC1=C(Cl)C=C(Cl)C(Cl)=C1CC1=C(O)C(Cl)=CC(Cl)=C1Cl ACGUYXCXAPNIKK-UHFFFAOYSA-N 0.000 description 2
• 229960004068 hexachlorophene Drugs 0.000 description 2
• JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 description 2
• WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 2
• RONFGUROBZGJKP-UHFFFAOYSA-N iminoctadine Chemical compound NC(N)=NCCCCCCCCNCCCCCCCCN=C(N)N RONFGUROBZGJKP-UHFFFAOYSA-N 0.000 description 2
• 230000001771 impaired effect Effects 0.000 description 2
• 238000011065 in-situ storage Methods 0.000 description 2
• 238000010348 incorporation Methods 0.000 description 2
• 230000001939 inductive effect Effects 0.000 description 2
• 239000004615 ingredient Substances 0.000 description 2
• 210000000936 intestine Anatomy 0.000 description 2
• 229960002630 ipratropium bromide monohydrate Drugs 0.000 description 2
• ONUFESLQCSAYKA-UHFFFAOYSA-N iprodione Chemical compound O=C1N(C(=O)NC(C)C)CC(=O)N1C1=CC(Cl)=CC(Cl)=C1 ONUFESLQCSAYKA-UHFFFAOYSA-N 0.000 description 2
• DDFOUSQFMYRUQK-RCDICMHDSA-N isavuconazole Chemical compound C=1SC([C@H](C)[C@](O)(CN2N=CN=C2)C=2C(=CC=C(F)C=2)F)=NC=1C1=CC=C(C#N)C=C1 DDFOUSQFMYRUQK-RCDICMHDSA-N 0.000 description 2
• 229960000788 isavuconazole Drugs 0.000 description 2
• 229960004849 isoconazole Drugs 0.000 description 2
• PVTHJAPFENJVNC-MHRBZPPQSA-N kasugamycin Chemical compound N[C@H]1C[C@H](NC(=N)C(O)=O)[C@@H](C)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1O PVTHJAPFENJVNC-MHRBZPPQSA-N 0.000 description 2
• 230000002147 killing effect Effects 0.000 description 2
• 239000004922 lacquer Substances 0.000 description 2
• 235000021374 legumes Nutrition 0.000 description 2
• 210000000088 lip Anatomy 0.000 description 2
• 201000006506 lobomycosis Diseases 0.000 description 2
• 239000006210 lotion Substances 0.000 description 2
• 239000007937 lozenge Substances 0.000 description 2
• 239000011777 magnesium Substances 0.000 description 2
• HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
• 230000003211 malignant effect Effects 0.000 description 2
• 239000000594 mannitol Substances 0.000 description 2
• 235000010355 mannitol Nutrition 0.000 description 2
• 108010084926 mannuronan c-5-epimerase Proteins 0.000 description 2
• 239000003550 marker Substances 0.000 description 2
• 235000013372 meat Nutrition 0.000 description 2
• 238000002483 medication Methods 0.000 description 2
• 229960002523 mercuric chloride Drugs 0.000 description 2
• LWJROJCJINYWOX-UHFFFAOYSA-L mercury dichloride Chemical compound Cl[Hg]Cl LWJROJCJINYWOX-UHFFFAOYSA-L 0.000 description 2
• UKWHYYKOEPRTIC-UHFFFAOYSA-N mercury(ii) oxide Chemical compound [Hg]=O UKWHYYKOEPRTIC-UHFFFAOYSA-N 0.000 description 2
• ZQEIXNIJLIKNTD-GFCCVEGCSA-N metalaxyl-M Chemical compound COCC(=O)N([C@H](C)C(=O)OC)C1=C(C)C=CC=C1C ZQEIXNIJLIKNTD-GFCCVEGCSA-N 0.000 description 2
• ZQEIXNIJLIKNTD-UHFFFAOYSA-N methyl N-(2,6-dimethylphenyl)-N-(methoxyacetyl)alaninate Chemical compound COCC(=O)N(C(C)C(=O)OC)C1=C(C)C=CC=C1C ZQEIXNIJLIKNTD-UHFFFAOYSA-N 0.000 description 2
• CJPQIRJHIZUAQP-UHFFFAOYSA-N methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)alaninate Chemical compound CC=1C=CC=C(C)C=1N(C(C)C(=O)OC)C(=O)CC1=CC=CC=C1 CJPQIRJHIZUAQP-UHFFFAOYSA-N 0.000 description 2
• CIEXPHRYOLIQQD-UHFFFAOYSA-N methyl N-(2,6-dimethylphenyl)-N-2-furoylalaninate Chemical compound CC=1C=CC=C(C)C=1N(C(C)C(=O)OC)C(=O)C1=CC=CO1 CIEXPHRYOLIQQD-UHFFFAOYSA-N 0.000 description 2
• 229920000257 metiram Polymers 0.000 description 2
• 239000006994 mh medium Substances 0.000 description 2
• 229960002159 micafungin Drugs 0.000 description 2
• PIEUQSKUWLMALL-YABMTYFHSA-N micafungin Chemical compound C1=CC(OCCCCC)=CC=C1C1=CC(C=2C=CC(=CC=2)C(=O)N[C@@H]2C(N[C@H](C(=O)N3C[C@H](O)C[C@H]3C(=O)N[C@H](C(=O)N[C@H](C(=O)N3C[C@H](C)[C@H](O)[C@H]3C(=O)N[C@H](O)[C@H](O)C2)[C@H](O)CC(N)=O)[C@H](O)[C@@H](O)C=2C=C(OS(O)(=O)=O)C(O)=CC=2)[C@@H](C)O)=O)=NO1 PIEUQSKUWLMALL-YABMTYFHSA-N 0.000 description 2
• 239000004570 mortar (masonry) Substances 0.000 description 2
• 229940051866 mouthwash Drugs 0.000 description 2
• 210000004400 mucous membrane Anatomy 0.000 description 2
• 230000007935 neutral effect Effects 0.000 description 2
• NQDJXKOVJZTUJA-UHFFFAOYSA-N nevirapine Chemical compound C12=NC=CC=C2C(=O)NC=2C(C)=CC=NC=2N1C1CC1 NQDJXKOVJZTUJA-UHFFFAOYSA-N 0.000 description 2
• 229920001542 oligosaccharide Polymers 0.000 description 2
• 150000002482 oligosaccharides Chemical class 0.000 description 2
• 229960004031 omoconazole Drugs 0.000 description 2
• JMFOSJNGKJCTMJ-ZHZULCJRSA-N omoconazole Chemical compound C1=CN=CN1C(/C)=C(C=1C(=CC(Cl)=CC=1)Cl)\OCCOC1=CC=C(Cl)C=C1 JMFOSJNGKJCTMJ-ZHZULCJRSA-N 0.000 description 2
• 239000011368 organic material Substances 0.000 description 2
• UWVQIROCRJWDKL-UHFFFAOYSA-N oxadixyl Chemical compound CC=1C=CC=C(C)C=1N(C(=O)COC)N1CCOC1=O UWVQIROCRJWDKL-UHFFFAOYSA-N 0.000 description 2
• 229960003483 oxiconazole Drugs 0.000 description 2
• QRJJEGAJXVEBNE-MOHJPFBDSA-N oxiconazole Chemical compound ClC1=CC(Cl)=CC=C1CO\N=C(C=1C(=CC(Cl)=CC=1)Cl)\CN1C=NC=C1 QRJJEGAJXVEBNE-MOHJPFBDSA-N 0.000 description 2
• 230000003647 oxidation Effects 0.000 description 2
• 238000007254 oxidation reaction Methods 0.000 description 2
• AMEKQAFGQBKLKX-UHFFFAOYSA-N oxycarboxin Chemical compound O=S1(=O)CCOC(C)=C1C(=O)NC1=CC=CC=C1 AMEKQAFGQBKLKX-UHFFFAOYSA-N 0.000 description 2
• 210000000496 pancreas Anatomy 0.000 description 2
• 244000045947 parasite Species 0.000 description 2
• 239000003182 parenteral nutrition solution Substances 0.000 description 2
• 239000006072 paste Substances 0.000 description 2
• WBTYBAGIHOISOQ-UHFFFAOYSA-N pent-4-en-1-yl 2-[(2-furylmethyl)(imidazol-1-ylcarbonyl)amino]butanoate Chemical compound C1=CN=CN1C(=O)N(C(CC)C(=O)OCCCC=C)CC1=CC=CO1 WBTYBAGIHOISOQ-UHFFFAOYSA-N 0.000 description 2
• IZUPBVBPLAPZRR-UHFFFAOYSA-N pentachlorophenol Chemical compound OC1=C(Cl)C(Cl)=C(Cl)C(Cl)=C1Cl IZUPBVBPLAPZRR-UHFFFAOYSA-N 0.000 description 2
• 235000019319 peptone Nutrition 0.000 description 2
• KHIWWQKSHDUIBK-UHFFFAOYSA-N periodic acid Chemical compound OI(=O)(=O)=O KHIWWQKSHDUIBK-UHFFFAOYSA-N 0.000 description 2
• KDNVJBRRDKAHDA-UHFFFAOYSA-L phenyl-[3-[[3-(phenylmercuriooxysulfonyl)naphthalen-2-yl]methyl]naphthalen-2-yl]sulfonyloxymercury Chemical compound C=1C2=CC=CC=C2C=C(CC=2C(=CC3=CC=CC=C3C=2)S(=O)(=O)O[Hg]C=2C=CC=CC=2)C=1S(=O)(=O)O[Hg]C1=CC=CC=C1 KDNVJBRRDKAHDA-UHFFFAOYSA-L 0.000 description 2
• ZJAOAACCNHFJAH-UHFFFAOYSA-N phosphonoformic acid Chemical compound OC(=O)P(O)(O)=O ZJAOAACCNHFJAH-UHFFFAOYSA-N 0.000 description 2
• 239000006187 pill Substances 0.000 description 2
• 239000011505 plaster Substances 0.000 description 2
• 201000000317 pneumocystosis Diseases 0.000 description 2
• 229920002635 polyurethane Polymers 0.000 description 2
• 229960001589 posaconazole Drugs 0.000 description 2
• RAGOYPUPXAKGKH-XAKZXMRKSA-N posaconazole Chemical compound O=C1N([C@H]([C@H](C)O)CC)N=CN1C1=CC=C(N2CCN(CC2)C=2C=CC(OC[C@H]3C[C@@](CN4N=CN=C4)(OC3)C=3C(=CC(F)=CC=3)F)=CC=2)C=C1 RAGOYPUPXAKGKH-XAKZXMRKSA-N 0.000 description 2
• 239000011178 precast concrete Substances 0.000 description 2
• 238000001556 precipitation Methods 0.000 description 2
• 239000002243 precursor Substances 0.000 description 2
• WHHIPMZEDGBUCC-UHFFFAOYSA-N probenazole Chemical compound C1=CC=C2C(OCC=C)=NS(=O)(=O)C2=C1 WHHIPMZEDGBUCC-UHFFFAOYSA-N 0.000 description 2
• 230000035752 proliferative phase Effects 0.000 description 2
• 230000002035 prolonged effect Effects 0.000 description 2
• 230000001737 promoting effect Effects 0.000 description 2
• 230000000069 prophylactic effect Effects 0.000 description 2
• KKMLIVYBGSAJPM-UHFFFAOYSA-L propineb Chemical compound [Zn+2].[S-]C(=S)NC(C)CNC([S-])=S KKMLIVYBGSAJPM-UHFFFAOYSA-L 0.000 description 2
• DWTVBEZBWMDXIY-UHFFFAOYSA-N pyrametostrobin Chemical compound COC(=O)N(OC)C1=CC=CC=C1COC1=C(C)C(C=2C=CC=CC=2)=NN1C DWTVBEZBWMDXIY-UHFFFAOYSA-N 0.000 description 2
• URXNNPCNKVAQRA-XMHGGMMESA-N pyraoxystrobin Chemical compound CO\C=C(\C(=O)OC)C1=CC=CC=C1COC1=CC(C=2C=CC(Cl)=CC=2)=NN1C URXNNPCNKVAQRA-XMHGGMMESA-N 0.000 description 2
• CRFYLQMIDWBKRT-LPYMAVHISA-N pyribencarb Chemical compound C1=C(Cl)C(CNC(=O)OC)=CC(C(\C)=N\OCC=2N=C(C)C=CC=2)=C1 CRFYLQMIDWBKRT-LPYMAVHISA-N 0.000 description 2
• DHTJFQWHCVTNRY-OEMAIJDKSA-N pyrisoxazole Chemical compound C1([C@@]2(C)CC(ON2C)C=2C=CC(Cl)=CC=2)=CC=CN=C1 DHTJFQWHCVTNRY-OEMAIJDKSA-N 0.000 description 2
• 229960003811 pyrithione disulfide Drugs 0.000 description 2
• 150000003856 quaternary ammonium compounds Chemical class 0.000 description 2
• MRUMAIRJPMUAPZ-UHFFFAOYSA-N quinolin-8-ol;sulfuric acid Chemical compound OS(O)(=O)=O.C1=CN=C2C(O)=CC=CC2=C1 MRUMAIRJPMUAPZ-UHFFFAOYSA-N 0.000 description 2
• XSCHRSMBECNVNS-UHFFFAOYSA-N quinoxaline Chemical compound N1=CC=NC2=CC=CC=C21 XSCHRSMBECNVNS-UHFFFAOYSA-N 0.000 description 2
• 230000005855 radiation Effects 0.000 description 2
• OPAHEYNNJWPQPX-RCDICMHDSA-N ravuconazole Chemical compound C=1SC([C@H](C)[C@](O)(CN2N=CN=C2)C=2C(=CC(F)=CC=2)F)=NC=1C1=CC=C(C#N)C=C1 OPAHEYNNJWPQPX-RCDICMHDSA-N 0.000 description 2
• 229950004154 ravuconazole Drugs 0.000 description 2
• 238000007634 remodeling Methods 0.000 description 2
• 150000003839 salts Chemical class 0.000 description 2
• 239000004576 sand Substances 0.000 description 2
• 229920006395 saturated elastomer Polymers 0.000 description 2
• 238000012216 screening Methods 0.000 description 2
• 235000014102 seafood Nutrition 0.000 description 2
• 208000013223 septicemia Diseases 0.000 description 2
• 229960005429 sertaconazole Drugs 0.000 description 2
• 230000035939 shock Effects 0.000 description 2
• 239000004590 silicone sealant Substances 0.000 description 2
• 239000002884 skin cream Substances 0.000 description 2
• 235000019333 sodium laurylsulphate Nutrition 0.000 description 2
• 210000004872 soft tissue Anatomy 0.000 description 2
• 239000008279 sol Substances 0.000 description 2
• 239000007921 spray Substances 0.000 description 2
• 239000012058 sterile packaged powder Substances 0.000 description 2
• 239000008223 sterile water Substances 0.000 description 2
• 239000003206 sterilizing agent Substances 0.000 description 2
• UCSJYZPVAKXKNQ-HZYVHMACSA-N streptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O UCSJYZPVAKXKNQ-HZYVHMACSA-N 0.000 description 2
• 239000000758 substrate Substances 0.000 description 2
• 229940124530 sulfonamide Drugs 0.000 description 2
• 150000003456 sulfonamides Chemical class 0.000 description 2
• 229910052717 sulfur Inorganic materials 0.000 description 2
• 239000000829 suppository Substances 0.000 description 2
• 230000002195 synergetic effect Effects 0.000 description 2
• 238000003786 synthesis reaction Methods 0.000 description 2
• 239000003826 tablet Substances 0.000 description 2
• 229960000580 terconazole Drugs 0.000 description 2
• 235000019364 tetracycline Nutrition 0.000 description 2
• 150000003522 tetracyclines Chemical class 0.000 description 2
• ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical compound O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 description 2
• 238000002560 therapeutic procedure Methods 0.000 description 2
• 239000004308 thiabendazole Substances 0.000 description 2
• 229960004546 thiabendazole Drugs 0.000 description 2
• 235000010296 thiabendazole Nutrition 0.000 description 2
• WJCNZQLZVWNLKY-UHFFFAOYSA-N thiabendazole Chemical compound S1C=NC(C=2NC3=CC=CC=C3N=2)=C1 WJCNZQLZVWNLKY-UHFFFAOYSA-N 0.000 description 2
• YFNCATAIYKQPOO-UHFFFAOYSA-N thiophanate Chemical compound CCOC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OCC YFNCATAIYKQPOO-UHFFFAOYSA-N 0.000 description 2
• QGHREAKMXXNCOA-UHFFFAOYSA-N thiophanate-methyl Chemical compound COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC QGHREAKMXXNCOA-UHFFFAOYSA-N 0.000 description 2
• 229960004089 tigecycline Drugs 0.000 description 2
• FPZLLRFZJZRHSY-HJYUBDRYSA-N tigecycline Chemical class C([C@H]1C2)C3=C(N(C)C)C=C(NC(=O)CNC(C)(C)C)C(O)=C3C(=O)C1=C(O)[C@@]1(O)[C@@H]2[C@H](N(C)C)C(O)=C(C(N)=O)C1=O FPZLLRFZJZRHSY-HJYUBDRYSA-N 0.000 description 2
• 201000009642 tinea barbae Diseases 0.000 description 2
• 201000003875 tinea corporis Diseases 0.000 description 2
• 231100000765 toxin Toxicity 0.000 description 2
• 108700012359 toxins Proteins 0.000 description 2
• 238000002627 tracheal intubation Methods 0.000 description 2
• 238000002054 transplantation Methods 0.000 description 2
• 150000003852 triazoles Chemical class 0.000 description 2
• 229930013292 trichothecene Natural products 0.000 description 2
• 239000012137 tryptone Substances 0.000 description 2
• 235000012431 wafers Nutrition 0.000 description 2
• 239000001993 wax Substances 0.000 description 2
• 210000002268 wool Anatomy 0.000 description 2
• 229910052725 zinc Inorganic materials 0.000 description 2
• 239000011701 zinc Substances 0.000 description 2
• DUBNHZYBDBBJHD-UHFFFAOYSA-L ziram Chemical compound [Zn+2].CN(C)C([S-])=S.CN(C)C([S-])=S DUBNHZYBDBBJHD-UHFFFAOYSA-L 0.000 description 2
• YNWVFADWVLCOPU-MDWZMJQESA-N (1E)-1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pent-1-en-3-ol Chemical compound C1=NC=NN1/C(C(O)C(C)(C)C)=C/C1=CC=C(Cl)C=C1 YNWVFADWVLCOPU-MDWZMJQESA-N 0.000 description 1
• WRGKWWRFSUGDPX-HUUCEWRRSA-N (1R,2R)-1-(4-chlorophenyl)-2-(1,2,4-triazol-1-yl)cycloheptan-1-ol Chemical compound N1([C@@H]2CCCCC[C@@]2(O)C=2C=CC(Cl)=CC=2)C=NC=N1 WRGKWWRFSUGDPX-HUUCEWRRSA-N 0.000 description 1
• XERJKGMBORTKEO-VZUCSPMQSA-N (1e)-2-(ethylcarbamoylamino)-n-methoxy-2-oxoethanimidoyl cyanide Chemical compound CCNC(=O)NC(=O)C(\C#N)=N\OC XERJKGMBORTKEO-VZUCSPMQSA-N 0.000 description 1
• MYUPFXPCYUISAG-UHFFFAOYSA-N (2,4-dichlorophenyl)(phenyl)pyrimidin-5-ylmethanol Chemical compound C=1N=CN=CC=1C(C=1C(=CC(Cl)=CC=1)Cl)(O)C1=CC=CC=C1 MYUPFXPCYUISAG-UHFFFAOYSA-N 0.000 description 1
• PTKVPQXEKZOPNA-UHFFFAOYSA-N (2,4-dinitro-6-octan-2-ylphenyl) methylsulfanylformate Chemical compound CCCCCCC(C)C1=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C1OC(=O)SC PTKVPQXEKZOPNA-UHFFFAOYSA-N 0.000 description 1
• QQHRSBLQLJPBPJ-UHFFFAOYSA-N (2,4-dinitro-6-pentan-2-ylphenyl) propan-2-yl carbonate Chemical compound CCCC(C)C1=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C1OC(=O)OC(C)C QQHRSBLQLJPBPJ-UHFFFAOYSA-N 0.000 description 1
• YHVJMJFNSRLYIC-WEVVVXLNSA-N (2,6-dinitro-4-octan-2-ylphenyl) (e)-but-2-enoate Chemical compound CCCCCCC(C)C1=CC([N+]([O-])=O)=C(OC(=O)\C=C\C)C([N+]([O-])=O)=C1 YHVJMJFNSRLYIC-WEVVVXLNSA-N 0.000 description 1
• NHOWDZOIZKMVAI-UHFFFAOYSA-N (2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol Chemical compound C=1N=CN=CC=1C(C=1C(=CC=CC=1)Cl)(O)C1=CC=C(Cl)C=C1 NHOWDZOIZKMVAI-UHFFFAOYSA-N 0.000 description 1
• SAPGTCDSBGMXCD-UHFFFAOYSA-N (2-chlorophenyl)-(4-fluorophenyl)-pyrimidin-5-ylmethanol Chemical compound C=1N=CN=CC=1C(C=1C(=CC=CC=1)Cl)(O)C1=CC=C(F)C=C1 SAPGTCDSBGMXCD-UHFFFAOYSA-N 0.000 description 1
• IXNUTQCZWAHNPN-UHFFFAOYSA-N (2-tert-butyl-4,6-dinitrophenyl) ethyl carbonate Chemical compound CCOC(=O)OC1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1C(C)(C)C IXNUTQCZWAHNPN-UHFFFAOYSA-N 0.000 description 1
• OILXMJHPFNGGTO-UHFFFAOYSA-N (22E)-(24xi)-24-methylcholesta-5,22-dien-3beta-ol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(C)C(C)C)C1(C)CC2 OILXMJHPFNGGTO-UHFFFAOYSA-N 0.000 description 1
• RQOCXCFLRBRBCS-UHFFFAOYSA-N (22E)-cholesta-5,7,22-trien-3beta-ol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CCC(C)C)CCC33)C)C3=CC=C21 RQOCXCFLRBRBCS-UHFFFAOYSA-N 0.000 description 1
• ZMYFCFLJBGAQRS-IRXDYDNUSA-N (2R,3S)-epoxiconazole Chemical compound C1=CC(F)=CC=C1[C@@]1(CN2N=CN=C2)[C@H](C=2C(=CC=CC=2)Cl)O1 ZMYFCFLJBGAQRS-IRXDYDNUSA-N 0.000 description 1
• RYAUSSKQMZRMAI-ALOPSCKCSA-N (2S,6R)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine Chemical compound C=1C=C(C(C)(C)C)C=CC=1CC(C)CN1C[C@H](C)O[C@H](C)C1 RYAUSSKQMZRMAI-ALOPSCKCSA-N 0.000 description 1
• URDNHJIVMYZFRT-KGLIPLIRSA-N (2r,3r)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)pentan-3-ol Chemical compound C([C@H]([C@H](O)C(C)(C)C)N1N=CN=C1)C1=CC=C(Cl)C=C1Cl URDNHJIVMYZFRT-KGLIPLIRSA-N 0.000 description 1
• LNAZSHAWQACDHT-XIYTZBAFSA-N (2r,3r,4s,5r,6s)-4,5-dimethoxy-2-(methoxymethyl)-3-[(2s,3r,4s,5r,6r)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxy-6-[(2r,3r,4s,5r,6r)-4,5,6-trimethoxy-2-(methoxymethyl)oxan-3-yl]oxyoxane Chemical compound CO[C@@H]1[C@@H](OC)[C@H](OC)[C@@H](COC)O[C@H]1O[C@H]1[C@H](OC)[C@@H](OC)[C@H](O[C@H]2[C@@H]([C@@H](OC)[C@H](OC)O[C@@H]2COC)OC)O[C@@H]1COC LNAZSHAWQACDHT-XIYTZBAFSA-N 0.000 description 1
• CXNPLSGKWMLZPZ-GIFSMMMISA-N (2r,3r,6s)-3-[[(3s)-3-amino-5-[carbamimidoyl(methyl)amino]pentanoyl]amino]-6-(4-amino-2-oxopyrimidin-1-yl)-3,6-dihydro-2h-pyran-2-carboxylic acid Chemical compound O1[C@@H](C(O)=O)[C@H](NC(=O)C[C@@H](N)CCN(C)C(N)=N)C=C[C@H]1N1C(=O)N=C(N)C=C1 CXNPLSGKWMLZPZ-GIFSMMMISA-N 0.000 description 1
• XDEHMKQLKPZERH-BYPYZUCNSA-N (2s)-2-amino-3-methylbutanamide Chemical compound CC(C)[C@H](N)C(N)=O XDEHMKQLKPZERH-BYPYZUCNSA-N 0.000 description 1
• LDVVMCZRFWMZSG-OLQVQODUSA-N (3ar,7as)-2-(trichloromethylsulfanyl)-3a,4,7,7a-tetrahydroisoindole-1,3-dione Chemical compound C1C=CC[C@H]2C(=O)N(SC(Cl)(Cl)Cl)C(=O)[C@H]21 LDVVMCZRFWMZSG-OLQVQODUSA-N 0.000 description 1
• QNQBPPQLRODXET-AIMHRHHOSA-N (3e,5s)-3-[[(1s,2r,4as,6r,8ar)-1,6-dimethyl-2-[(e)-prop-1-enyl]-4a,5,6,7,8,8a-hexahydro-2h-naphthalen-1-yl]-hydroxymethylidene]-5-(hydroxymethyl)-1-methylpyrrolidine-2,4-dione Chemical compound O/C([C@@]1(C)[C@@H]2CC[C@@H](C)C[C@H]2C=C[C@H]1/C=C/C)=C1\C(=O)[C@H](CO)N(C)C1=O QNQBPPQLRODXET-AIMHRHHOSA-N 0.000 description 1
• SGKRLCUYIXIAHR-AKNGSSGZSA-N (4s,4ar,5s,5ar,6r,12ar)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide Chemical compound C1=CC=C2[C@H](C)[C@@H]([C@H](O)[C@@H]3[C@](C(O)=C(C(N)=O)C(=O)[C@H]3N(C)C)(O)C3=O)C3=C(O)C2=C1O SGKRLCUYIXIAHR-AKNGSSGZSA-N 0.000 description 1
• FFTVPQUHLQBXQZ-KVUCHLLUSA-N (4s,4as,5ar,12ar)-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide Chemical compound C1C2=C(N(C)C)C=CC(O)=C2C(O)=C2[C@@H]1C[C@H]1[C@H](N(C)C)C(=O)C(C(N)=O)=C(O)[C@@]1(O)C2=O FFTVPQUHLQBXQZ-KVUCHLLUSA-N 0.000 description 1
• GUXHBMASAHGULD-SEYHBJAFSA-N (4s,4as,5as,6s,12ar)-7-chloro-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide Chemical compound C1([C@H]2O)=C(Cl)C=CC(O)=C1C(O)=C1[C@@H]2C[C@H]2[C@H](N(C)C)C(=O)C(C(N)=O)=C(O)[C@@]2(O)C1=O GUXHBMASAHGULD-SEYHBJAFSA-N 0.000 description 1
• PPDBOQMNKNNODG-NTEUORMPSA-N (5E)-5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentanol Chemical compound C1=NC=NN1CC1(O)C(C)(C)CC\C1=C/C1=CC=C(Cl)C=C1 PPDBOQMNKNNODG-NTEUORMPSA-N 0.000 description 1
• SQEBMLCQNJOCBG-HVHJFMEUSA-N (5s)-3-(hydroxymethyl)-5-methoxy-4-methyl-5-[(e)-2-phenylethenyl]furan-2-one Chemical compound C=1C=CC=CC=1/C=C/[C@]1(OC)OC(=O)C(CO)=C1C SQEBMLCQNJOCBG-HVHJFMEUSA-N 0.000 description 1
• WDLWHQDACQUCJR-ZAMMOSSLSA-N (6r,7r)-7-[[(2r)-2-azaniumyl-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-[(e)-prop-1-enyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)/C=C/C)C(O)=O)=CC=C(O)C=C1 WDLWHQDACQUCJR-ZAMMOSSLSA-N 0.000 description 1
• UCTWMZQNUQWSLP-VIFPVBQESA-N (R)-adrenaline Chemical compound CNC[C@H](O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-VIFPVBQESA-N 0.000 description 1
• 229930182837 (R)-adrenaline Natural products 0.000 description 1
• NDAUXUAQIAJITI-LBPRGKRZSA-N (R)-salbutamol Chemical compound CC(C)(C)NC[C@H](O)C1=CC=C(O)C(CO)=C1 NDAUXUAQIAJITI-LBPRGKRZSA-N 0.000 description 1
• XUBOMFCQGDBHNK-JTQLQIEISA-N (S)-gatifloxacin Chemical compound FC1=CC(C(C(C(O)=O)=CN2C3CC3)=O)=C2C(OC)=C1N1CCN[C@@H](C)C1 XUBOMFCQGDBHNK-JTQLQIEISA-N 0.000 description 1
• MBMQEIFVQACCCH-XVNBXDOJSA-N (S,E)-Zearalenone Chemical compound O=C1OC(C)CCCC(=O)CCC\C=C\C2=CC(O)=CC(O)=C21 MBMQEIFVQACCCH-XVNBXDOJSA-N 0.000 description 1
• 229920000985 (beta-D-Mannuronate)n Polymers 0.000 description 1
• UNQDVBLGFWIFGX-UHFFFAOYSA-M (carbamoylamino)-phenylmercury Chemical compound NC(=O)N[Hg]C1=CC=CC=C1 UNQDVBLGFWIFGX-UHFFFAOYSA-M 0.000 description 1
• CKPCAYZTYMHQEX-NBVRZTHBSA-N (e)-1-(2,4-dichlorophenyl)-n-methoxy-2-pyridin-3-ylethanimine Chemical compound C=1C=C(Cl)C=C(Cl)C=1C(=N/OC)/CC1=CC=CN=C1 CKPCAYZTYMHQEX-NBVRZTHBSA-N 0.000 description 1
• DEVUYWTZRXOMSI-UHFFFAOYSA-N (sulfamoylamino)benzene Chemical compound NS(=O)(=O)NC1=CC=CC=C1 DEVUYWTZRXOMSI-UHFFFAOYSA-N 0.000 description 1
• JYEUMXHLPRZUAT-UHFFFAOYSA-N 1,2,3-triazine Chemical compound C1=CN=NN=C1 JYEUMXHLPRZUAT-UHFFFAOYSA-N 0.000 description 1
• JCIIKRHCWVHVFF-UHFFFAOYSA-N 1,2,4-thiadiazol-5-amine;hydrochloride Chemical compound Cl.NC1=NC=NS1 JCIIKRHCWVHVFF-UHFFFAOYSA-N 0.000 description 1
• WBEJYOJJBDISQU-UHFFFAOYSA-N 1,2-Dibromo-3-chloropropane Chemical compound ClCC(Br)CBr WBEJYOJJBDISQU-UHFFFAOYSA-N 0.000 description 1
• NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 description 1
• TUBQDCKAWGHZPF-UHFFFAOYSA-N 1,3-benzothiazol-2-ylsulfanylmethyl thiocyanate Chemical compound C1=CC=C2SC(SCSC#N)=NC2=C1 TUBQDCKAWGHZPF-UHFFFAOYSA-N 0.000 description 1
• IMLSAISZLJGWPP-UHFFFAOYSA-N 1,3-dithiolane Chemical compound C1CSCS1 IMLSAISZLJGWPP-UHFFFAOYSA-N 0.000 description 1
• OGYGFUAIIOPWQD-UHFFFAOYSA-N 1,3-thiazolidine Chemical compound C1CSCN1 OGYGFUAIIOPWQD-UHFFFAOYSA-N 0.000 description 1
• UBCHPRBFMUDMNC-UHFFFAOYSA-N 1-(1-adamantyl)ethanamine Chemical compound C1C(C2)CC3CC2CC1(C(N)C)C3 UBCHPRBFMUDMNC-UHFFFAOYSA-N 0.000 description 1
• JWUCHKBSVLQQCO-UHFFFAOYSA-N 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Chemical compound C=1C=C(F)C=CC=1C(C=1C(=CC=CC=1)F)(O)CN1C=NC=N1 JWUCHKBSVLQQCO-UHFFFAOYSA-N 0.000 description 1
• GUDQIKIAWOAOFP-UHFFFAOYSA-N 1-(2-hydroxyphenyl)butan-1-one Chemical compound CCCC(=O)C1=CC=CC=C1O GUDQIKIAWOAOFP-UHFFFAOYSA-N 0.000 description 1
• OWEGWHBOCFMBLP-UHFFFAOYSA-N 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one Chemical compound C1=CN=CN1C(C(=O)C(C)(C)C)OC1=CC=C(Cl)C=C1 OWEGWHBOCFMBLP-UHFFFAOYSA-N 0.000 description 1
• WURBVZBTWMNKQT-UHFFFAOYSA-N 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one Chemical compound C1=NC=NN1C(C(=O)C(C)(C)C)OC1=CC=C(Cl)C=C1 WURBVZBTWMNKQT-UHFFFAOYSA-N 0.000 description 1
• PXMNMQRDXWABCY-UHFFFAOYSA-N 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Chemical compound C1=NC=NN1CC(O)(C(C)(C)C)CCC1=CC=C(Cl)C=C1 PXMNMQRDXWABCY-UHFFFAOYSA-N 0.000 description 1
• VGPIBGGRCVEHQZ-UHFFFAOYSA-N 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-ol Chemical compound C1=NC=NN1C(C(O)C(C)(C)C)OC(C=C1)=CC=C1C1=CC=CC=C1 VGPIBGGRCVEHQZ-UHFFFAOYSA-N 0.000 description 1
• ZZVVDIVWGXTDRQ-UHFFFAOYSA-N 1-[(4-tert-butylphenyl)methylsulfanyl]-1-butylsulfanyl-n-pyridin-3-ylmethanimine Chemical compound C=1C=CN=CC=1N=C(SCCCC)SCC1=CC=C(C(C)(C)C)C=C1 ZZVVDIVWGXTDRQ-UHFFFAOYSA-N 0.000 description 1
• LQDARGUHUSPFNL-UHFFFAOYSA-N 1-[2-(2,4-dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]1,2,4-triazole Chemical compound C=1C=C(Cl)C=C(Cl)C=1C(COC(F)(F)C(F)F)CN1C=NC=N1 LQDARGUHUSPFNL-UHFFFAOYSA-N 0.000 description 1
• WKBPZYKAUNRMKP-UHFFFAOYSA-N 1-[2-(2,4-dichlorophenyl)pentyl]1,2,4-triazole Chemical compound C=1C=C(Cl)C=C(Cl)C=1C(CCC)CN1C=NC=N1 WKBPZYKAUNRMKP-UHFFFAOYSA-N 0.000 description 1
• PZBPKYOVPCNPJY-UHFFFAOYSA-N 1-[2-(allyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole Chemical compound ClC1=CC(Cl)=CC=C1C(OCC=C)CN1C=NC=C1 PZBPKYOVPCNPJY-UHFFFAOYSA-N 0.000 description 1
• YIKWKLYQRFRGPM-UHFFFAOYSA-N 1-dodecylguanidine acetate Chemical compound CC(O)=O.CCCCCCCCCCCCN=C(N)N YIKWKLYQRFRGPM-UHFFFAOYSA-N 0.000 description 1
• CPKVUHPKYQGHMW-UHFFFAOYSA-N 1-ethenylpyrrolidin-2-one;molecular iodine Chemical compound II.C=CN1CCCC1=O CPKVUHPKYQGHMW-UHFFFAOYSA-N 0.000 description 1
• PFFIDZXUXFLSSR-UHFFFAOYSA-N 1-methyl-N-[2-(4-methylpentan-2-yl)-3-thienyl]-3-(trifluoromethyl)pyrazole-4-carboxamide Chemical compound S1C=CC(NC(=O)C=2C(=NN(C)C=2)C(F)(F)F)=C1C(C)CC(C)C PFFIDZXUXFLSSR-UHFFFAOYSA-N 0.000 description 1
• QXHHHPZILQDDPS-UHFFFAOYSA-N 1-{2-[(2-chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl)ethyl}imidazole Chemical compound S1C=CC(COC(CN2C=NC=C2)C=2C(=CC(Cl)=CC=2)Cl)=C1Cl QXHHHPZILQDDPS-UHFFFAOYSA-N 0.000 description 1
• 108020004465 16S ribosomal RNA Proteins 0.000 description 1
• WEYSQARHSRZNTC-UHFFFAOYSA-N 1h-benzimidazol-2-ylcarbamic acid Chemical class C1=CC=C2NC(NC(=O)O)=NC2=C1 WEYSQARHSRZNTC-UHFFFAOYSA-N 0.000 description 1
• SVPKNMBRVBMTLB-UHFFFAOYSA-N 2,3-dichloronaphthalene-1,4-dione Chemical compound C1=CC=C2C(=O)C(Cl)=C(Cl)C(=O)C2=C1 SVPKNMBRVBMTLB-UHFFFAOYSA-N 0.000 description 1
• KVJOLVBEUYUHLD-UHFFFAOYSA-M 2,3-dihydroxypropylsulfanyl(ethyl)mercury Chemical compound CC[Hg]SCC(O)CO KVJOLVBEUYUHLD-UHFFFAOYSA-M 0.000 description 1
• NIOPZPCMRQGZCE-WEVVVXLNSA-N 2,4-dinitro-6-(octan-2-yl)phenyl (E)-but-2-enoate Chemical compound CCCCCCC(C)C1=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C1OC(=O)\C=C\C NIOPZPCMRQGZCE-WEVVVXLNSA-N 0.000 description 1
• UFBJCMHMOXMLKC-UHFFFAOYSA-N 2,4-dinitrophenol Chemical compound OC1=CC=C([N+]([O-])=O)C=C1[N+]([O-])=O UFBJCMHMOXMLKC-UHFFFAOYSA-N 0.000 description 1
• XEPBBUCQCXXTGR-UHFFFAOYSA-N 2,5-dimethyl-n-phenylfuran-3-carboxamide Chemical compound O1C(C)=CC(C(=O)NC=2C=CC=CC=2)=C1C XEPBBUCQCXXTGR-UHFFFAOYSA-N 0.000 description 1
• YTOPFCCWCSOHFV-UHFFFAOYSA-N 2,6-dimethyl-4-tridecylmorpholine Chemical compound CCCCCCCCCCCCCN1CC(C)OC(C)C1 YTOPFCCWCSOHFV-UHFFFAOYSA-N 0.000 description 1
• HZJKXKUJVSEEFU-UHFFFAOYSA-N 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile Chemical compound C=1C=C(Cl)C=CC=1C(CCCC)(C#N)CN1C=NC=N1 HZJKXKUJVSEEFU-UHFFFAOYSA-N 0.000 description 1
• UFNOUKDBUJZYDE-UHFFFAOYSA-N 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Chemical compound C1=NC=NN1CC(O)(C=1C=CC(Cl)=CC=1)C(C)C1CC1 UFNOUKDBUJZYDE-UHFFFAOYSA-N 0.000 description 1
• KWLVWJPJKJMCSH-UHFFFAOYSA-N 2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide Chemical compound C1=C(OCC#C)C(OC)=CC(CCNC(=O)C(OCC#C)C=2C=CC(Cl)=CC=2)=C1 KWLVWJPJKJMCSH-UHFFFAOYSA-N 0.000 description 1
• YABFPHSQTSFWQB-UHFFFAOYSA-N 2-(4-fluorophenyl)-1-(1,2,4-triazol-1-yl)-3-(trimethylsilyl)propan-2-ol Chemical compound C=1C=C(F)C=CC=1C(O)(C[Si](C)(C)C)CN1C=NC=N1 YABFPHSQTSFWQB-UHFFFAOYSA-N 0.000 description 1
• JRURZFNGMMYBAO-UHFFFAOYSA-N 2-(dodecylamino)propanoic acid;sodium Chemical compound [Na].CCCCCCCCCCCCNC(C)C(O)=O JRURZFNGMMYBAO-UHFFFAOYSA-N 0.000 description 1
• GKFSEUGIFJFHAA-UHFFFAOYSA-N 2-(methoxyamino)acetamide Chemical compound CONCC(N)=O GKFSEUGIFJFHAA-UHFFFAOYSA-N 0.000 description 1
• VHVPQPYKVGDNFY-DFMJLFEVSA-N 2-[(2r)-butan-2-yl]-4-[4-[4-[4-[[(2r,4s)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one Chemical compound O=C1N([C@H](C)CC)N=CN1C1=CC=C(N2CCN(CC2)C=2C=CC(OC[C@@H]3O[C@](CN4N=CN=C4)(OC3)C=3C(=CC(Cl)=CC=3)Cl)=CC=2)C=C1 VHVPQPYKVGDNFY-DFMJLFEVSA-N 0.000 description 1
• OTWBGXPTCSGQEJ-UHFFFAOYSA-N 2-[(dimethylcarbamothioyldisulfanyl)carbothioylamino]ethylcarbamothioylsulfanyl n,n-dimethylcarbamodithioate Chemical compound CN(C)C(=S)SSC(=S)NCCNC(=S)SSC(=S)N(C)C OTWBGXPTCSGQEJ-UHFFFAOYSA-N 0.000 description 1
• MNHVNIJQQRJYDH-UHFFFAOYSA-N 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro-1,2,4-triazole-3-thione Chemical compound N1=CNC(=S)N1CC(C1(Cl)CC1)(O)CC1=CC=CC=C1Cl MNHVNIJQQRJYDH-UHFFFAOYSA-N 0.000 description 1
• DHVLDKHFGIVEIP-UHFFFAOYSA-N 2-bromo-2-(bromomethyl)pentanedinitrile Chemical compound BrCC(Br)(C#N)CCC#N DHVLDKHFGIVEIP-UHFFFAOYSA-N 0.000 description 1
• OGBSAJWRIPNIER-UHFFFAOYSA-N 2-chloro-6-(furan-2-ylmethoxy)-4-(trichloromethyl)pyridine Chemical compound ClC1=CC(C(Cl)(Cl)Cl)=CC(OCC=2OC=CC=2)=N1 OGBSAJWRIPNIER-UHFFFAOYSA-N 0.000 description 1
• RPCKKUFLSMORHB-UHFFFAOYSA-N 2-chloro-6-methoxy-4-(trichloromethyl)pyridine Chemical compound COC1=CC(C(Cl)(Cl)Cl)=CC(Cl)=N1 RPCKKUFLSMORHB-UHFFFAOYSA-N 0.000 description 1
• OWDLFBLNMPCXSD-UHFFFAOYSA-N 2-chloro-N-(2,6-dimethylphenyl)-N-(2-oxotetrahydrofuran-3-yl)acetamide Chemical compound CC1=CC=CC(C)=C1N(C(=O)CCl)C1C(=O)OCC1 OWDLFBLNMPCXSD-UHFFFAOYSA-N 0.000 description 1
• MIHIJWOEDDPOLG-UHFFFAOYSA-N 2-methoxyiminoacetic acid Chemical compound CON=CC(O)=O MIHIJWOEDDPOLG-UHFFFAOYSA-N 0.000 description 1
• 229940061334 2-phenylphenol Drugs 0.000 description 1
• ZRDUSMYWDRPZRM-UHFFFAOYSA-N 2-sec-butyl-4,6-dinitrophenyl 3-methylbut-2-enoate Chemical compound CCC(C)C1=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C1OC(=O)C=C(C)C ZRDUSMYWDRPZRM-UHFFFAOYSA-N 0.000 description 1
• SOUGWDPPRBKJEX-UHFFFAOYSA-N 3,5-dichloro-N-(1-chloro-3-methyl-2-oxopentan-3-yl)-4-methylbenzamide Chemical compound ClCC(=O)C(C)(CC)NC(=O)C1=CC(Cl)=C(C)C(Cl)=C1 SOUGWDPPRBKJEX-UHFFFAOYSA-N 0.000 description 1
• OVFHHJZHXHZIHT-UHFFFAOYSA-N 3-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-yl)quinazolin-4-one Chemical compound ClC1=CC(Cl)=CC=C1N1C(=O)C2=CC=CC=C2N=C1N1N=CN=C1 OVFHHJZHXHZIHT-UHFFFAOYSA-N 0.000 description 1
• SWIFBTMIPVESSG-UHFFFAOYSA-N 3-chloro-1,2-dinitronaphthalene Chemical class C1=CC=CC2=C([N+]([O-])=O)C([N+](=O)[O-])=C(Cl)C=C21 SWIFBTMIPVESSG-UHFFFAOYSA-N 0.000 description 1
• WYVVKGNFXHOCQV-UHFFFAOYSA-N 3-iodoprop-2-yn-1-yl butylcarbamate Chemical compound CCCCNC(=O)OCC#CI WYVVKGNFXHOCQV-UHFFFAOYSA-N 0.000 description 1
• ZXVONLUNISGICL-UHFFFAOYSA-N 4,6-dinitro-o-cresol Chemical compound CC1=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C1O ZXVONLUNISGICL-UHFFFAOYSA-N 0.000 description 1
• RQDJADAKIFFEKQ-UHFFFAOYSA-N 4-(4-chlorophenyl)-2-phenyl-2-(1,2,4-triazol-1-ylmethyl)butanenitrile Chemical compound C1=CC(Cl)=CC=C1CCC(C=1C=CC=CC=1)(C#N)CN1N=CN=C1 RQDJADAKIFFEKQ-UHFFFAOYSA-N 0.000 description 1
• ZRGHYHHYHYAJBT-UHFFFAOYSA-N 4-[(2-chlorophenyl)diazenyl]-3-methyl-2H-1,2-oxazol-5-one Chemical compound ClC1=C(C=CC=C1)N=NC1=C(NOC1=O)C ZRGHYHHYHYAJBT-UHFFFAOYSA-N 0.000 description 1
• YLDCUKJMEKGGFI-QCSRICIXSA-N 4-acetamidobenzoic acid;9-[(2r,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3h-purin-6-one;1-(dimethylamino)propan-2-ol Chemical compound CC(O)CN(C)C.CC(O)CN(C)C.CC(O)CN(C)C.CC(=O)NC1=CC=C(C(O)=O)C=C1.CC(=O)NC1=CC=C(C(O)=O)C=C1.CC(=O)NC1=CC=C(C(O)=O)C=C1.O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C(NC=NC2=O)=C2N=C1 YLDCUKJMEKGGFI-QCSRICIXSA-N 0.000 description 1
• WZRJTRPJURQBRM-UHFFFAOYSA-N 4-amino-n-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide;5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine Chemical compound O1C(C)=CC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1.COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 WZRJTRPJURQBRM-UHFFFAOYSA-N 0.000 description 1
• ZOMKCDYJHAQMCU-UHFFFAOYSA-N 4-butyl-1,2,4-triazole Chemical group CCCCN1C=NN=C1 ZOMKCDYJHAQMCU-UHFFFAOYSA-N 0.000 description 1
• BFTGQIQVUVTBJU-UHFFFAOYSA-N 5,6-dihydroimidazo[2,1-c][1,2,4]dithiazole-3-thione Chemical compound C1CN2C(=S)SSC2=N1 BFTGQIQVUVTBJU-UHFFFAOYSA-N 0.000 description 1
• OQMZNAMGEHIHNN-UHFFFAOYSA-N 7-Dehydrostigmasterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CC(CC)C(C)C)CCC33)C)C3=CC=C21 OQMZNAMGEHIHNN-UHFFFAOYSA-N 0.000 description 1
• GSDSWSVVBLHKDQ-UHFFFAOYSA-N 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid Chemical compound FC1=CC(C(C(C(O)=O)=C2)=O)=C3N2C(C)COC3=C1N1CCN(C)CC1 GSDSWSVVBLHKDQ-UHFFFAOYSA-N 0.000 description 1
• 206010063409 Acarodermatitis Diseases 0.000 description 1
• QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
• 241001133760 Acoelorraphe Species 0.000 description 1
• NLHHRLWOUZZQLW-UHFFFAOYSA-N Acrylonitrile Chemical compound C=CC#N NLHHRLWOUZZQLW-UHFFFAOYSA-N 0.000 description 1
• 235000009434 Actinidia chinensis Nutrition 0.000 description 1
• 244000298697 Actinidia deliciosa Species 0.000 description 1
• 235000009436 Actinidia deliciosa Nutrition 0.000 description 1
• 241000187254 Actinomadura madurae Species 0.000 description 1
• 241000157202 Actinomadura pelletieri Species 0.000 description 1
• 229930195730 Aflatoxin Natural products 0.000 description 1
• XWIYFDMXXLINPU-UHFFFAOYSA-N Aflatoxin G Chemical compound O=C1OCCC2=C1C(=O)OC1=C2C(OC)=CC2=C1C1C=COC1O2 XWIYFDMXXLINPU-UHFFFAOYSA-N 0.000 description 1
• 241000009794 Agaricomycetes Species 0.000 description 1
• 241000352035 Agaricostilbomycetes Species 0.000 description 1
• 235000016626 Agrimonia eupatoria Nutrition 0.000 description 1
• 244000307697 Agrimonia eupatoria Species 0.000 description 1
• JDLKFOPOAOFWQN-VIFPVBQESA-N Allicin Natural products C=CCS[S@](=O)CC=C JDLKFOPOAOFWQN-VIFPVBQESA-N 0.000 description 1
• 244000291564 Allium cepa Species 0.000 description 1
• 235000002732 Allium cepa var. cepa Nutrition 0.000 description 1
• GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
• 241001157812 Alternaria brassicicola Species 0.000 description 1
• 241000266344 Alternaria carotiincultae Species 0.000 description 1
• 241001053026 Alternaria conjuncta Species 0.000 description 1
• 241000795679 Alternaria euphorbiicola Species 0.000 description 1
• 241000412368 Alternaria gaisen Species 0.000 description 1
• 241000191412 Alternaria infectoria Species 0.000 description 1
• 241000212253 Alternaria panax Species 0.000 description 1
• 241000266347 Alternaria petroselini Species 0.000 description 1
• 241000266345 Alternaria radicina Species 0.000 description 1
• 241000429802 Alternaria saponariae Species 0.000 description 1
• 241000266343 Alternaria selini Species 0.000 description 1
• QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 1
• 244000144725 Amygdalus communis Species 0.000 description 1
• 235000011437 Amygdalus communis Nutrition 0.000 description 1
• 244000144730 Amygdalus persica Species 0.000 description 1
• 244000226021 Anacardium occidentale Species 0.000 description 1
• 206010002153 Anal fissure Diseases 0.000 description 1
• 244000099147 Ananas comosus Species 0.000 description 1
• 235000007119 Ananas comosus Nutrition 0.000 description 1
• 208000031295 Animal disease Diseases 0.000 description 1
• 241000195967 Anthoceros Species 0.000 description 1
• WZPBZJONDBGPKJ-UHFFFAOYSA-N Antibiotic SQ 26917 Natural products O=C1N(S(O)(=O)=O)C(C)C1NC(=O)C(=NOC(C)(C)C(O)=O)C1=CSC(N)=N1 WZPBZJONDBGPKJ-UHFFFAOYSA-N 0.000 description 1
• 208000016583 Anus disease Diseases 0.000 description 1
• 241000665614 Apiognomonia veneta Species 0.000 description 1
• 241001634940 Apiotrichum loubieri Species 0.000 description 1
• 235000017060 Arachis glabrata Nutrition 0.000 description 1
• 244000105624 Arachis hypogaea Species 0.000 description 1
• 235000010777 Arachis hypogaea Nutrition 0.000 description 1
• 235000018262 Arachis monticola Nutrition 0.000 description 1
• 241000726096 Aratinga Species 0.000 description 1
• 239000004475 Arginine Substances 0.000 description 1
• 241001326560 Arthoniomycetes Species 0.000 description 1
• 241000235349 Ascomycota Species 0.000 description 1
• 244000003416 Asparagus officinalis Species 0.000 description 1
• 235000005340 Asparagus officinalis Nutrition 0.000 description 1
• 206010003487 Aspergilloma Diseases 0.000 description 1
• 241000125121 Aspergillus carbonarius Species 0.000 description 1
• 241000131966 Aspergillus niveus Species 0.000 description 1
• 240000006439 Aspergillus oryzae Species 0.000 description 1
• 235000002247 Aspergillus oryzae Nutrition 0.000 description 1
• 241000228230 Aspergillus parasiticus Species 0.000 description 1
• 241000228257 Aspergillus sp. Species 0.000 description 1
• 241000416162 Astragalus gummifer Species 0.000 description 1
• AXRYRYVKAWYZBR-UHFFFAOYSA-N Atazanavir Natural products C=1C=C(C=2N=CC=CC=2)C=CC=1CN(NC(=O)C(NC(=O)OC)C(C)(C)C)CC(O)C(NC(=O)C(NC(=O)OC)C(C)(C)C)CC1=CC=CC=C1 AXRYRYVKAWYZBR-UHFFFAOYSA-N 0.000 description 1
• 108010019625 Atazanavir Sulfate Proteins 0.000 description 1
• 241000972773 Aulopiformes Species 0.000 description 1
• 241000271566 Aves Species 0.000 description 1
• 241000206761 Bacillariophyta Species 0.000 description 1
• 108010001478 Bacitracin Proteins 0.000 description 1
• 208000031729 Bacteremia Diseases 0.000 description 1
• 241000235579 Basidiobolus Species 0.000 description 1
• 241000221198 Basidiomycota Species 0.000 description 1
• MQIVNMHALJNFMG-ILYHAJGMSA-N Benquinox Chemical compound O/N=C(\C=C1)/C=C/C\1=N\NC(C1=CC=CC=C1)=O MQIVNMHALJNFMG-ILYHAJGMSA-N 0.000 description 1
• CWXYHOHYCJXYFQ-UHFFFAOYSA-N Betamipron Chemical compound OC(=O)CCNC(=O)C1=CC=CC=C1 CWXYHOHYCJXYFQ-UHFFFAOYSA-N 0.000 description 1
• 235000018185 Betula X alpestris Nutrition 0.000 description 1
• 235000018212 Betula X uliginosa Nutrition 0.000 description 1
• 241000228438 Bipolaris maydis Species 0.000 description 1
• 241001262168 Bipolaris stenospila Species 0.000 description 1
• 239000005738 Bixafen Substances 0.000 description 1
• 208000013883 Blast injury Diseases 0.000 description 1
• 241000760381 Blastocladiomycetes Species 0.000 description 1
• 241000760366 Blastocladiomycota Species 0.000 description 1
• 241000228405 Blastomyces dermatitidis Species 0.000 description 1
• 241001480061 Blumeria graminis Species 0.000 description 1
• 239000005739 Bordeaux mixture Substances 0.000 description 1
• 241000283690 Bos taurus Species 0.000 description 1
• 241001465180 Botrytis Species 0.000 description 1
• 241000123650 Botrytis cinerea Species 0.000 description 1
• 240000002791 Brassica napus Species 0.000 description 1
• 240000007124 Brassica oleracea Species 0.000 description 1
• 235000003899 Brassica oleracea var acephala Nutrition 0.000 description 1
• 235000011301 Brassica oleracea var capitata Nutrition 0.000 description 1
• 235000017647 Brassica oleracea var italica Nutrition 0.000 description 1
• 235000001169 Brassica oleracea var oleracea Nutrition 0.000 description 1
• 235000004977 Brassica sinapistrum Nutrition 0.000 description 1
• CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 description 1
• 239000005741 Bromuconazole Substances 0.000 description 1
• 235000004936 Bromus mango Nutrition 0.000 description 1
• 206010006473 Bronchopulmonary aspergillosis Diseases 0.000 description 1
• 206010006474 Bronchopulmonary aspergillosis allergic Diseases 0.000 description 1
• 241000195940 Bryophyta Species 0.000 description 1
• UDYPMBFHIUNFOF-UHFFFAOYSA-N C(C)O.C(CCCCCCCCC=C)(=O)O.[Na].[Na] Chemical compound C(C)O.C(CCCCCCCCC=C)(=O)O.[Na].[Na] UDYPMBFHIUNFOF-UHFFFAOYSA-N 0.000 description 1
• 101001107784 Caenorhabditis elegans Deoxyribonuclease-2 Proteins 0.000 description 1
• OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
• 241000282472 Canis lupus familiaris Species 0.000 description 1
• 241000283707 Capra Species 0.000 description 1
• 235000002566 Capsicum Nutrition 0.000 description 1
• 239000005745 Captan Substances 0.000 description 1
• KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 description 1
• 239000005973 Carvone Substances 0.000 description 1
• GNWUOVJNSFPWDD-XMZRARIVSA-M Cefoxitin sodium Chemical compound [Na+].N([C@]1(OC)C(N2C(=C(COC(N)=O)CS[C@@H]21)C([O-])=O)=O)C(=O)CC1=CC=CS1 GNWUOVJNSFPWDD-XMZRARIVSA-M 0.000 description 1
• 241001619326 Cephalosporium Species 0.000 description 1
• LZZYPRNAOMGNLH-UHFFFAOYSA-M Cetrimonium bromide Chemical compound [Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C LZZYPRNAOMGNLH-UHFFFAOYSA-M 0.000 description 1
• 241001307097 Chaconiaceae Species 0.000 description 1
• 240000006162 Chenopodium quinoa Species 0.000 description 1
• 229920001661 Chitosan Polymers 0.000 description 1
• REEFSLKDEDEWAO-UHFFFAOYSA-N Chloraniformethan Chemical compound ClC1=CC=C(NC(NC=O)C(Cl)(Cl)Cl)C=C1Cl REEFSLKDEDEWAO-UHFFFAOYSA-N 0.000 description 1
• GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical class C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 1
• VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
• 239000005747 Chlorothalonil Substances 0.000 description 1
• VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 description 1
• 208000008818 Chronic Mucocutaneous Candidiasis Diseases 0.000 description 1
• 206010009115 Chronic pulmonary histoplasmosis Diseases 0.000 description 1
• 241000760356 Chytridiomycetes Species 0.000 description 1
• 241000233652 Chytridiomycota Species 0.000 description 1
• VWFCHDSQECPREK-LURJTMIESA-N Cidofovir Chemical compound NC=1C=CN(C[C@@H](CO)OCP(O)(O)=O)C(=O)N=1 VWFCHDSQECPREK-LURJTMIESA-N 0.000 description 1
• 235000008733 Citrus aurantifolia Nutrition 0.000 description 1
• 235000005979 Citrus limon Nutrition 0.000 description 1
• 244000131522 Citrus pyriformis Species 0.000 description 1
• 241000555678 Citrus unshiu Species 0.000 description 1
• 240000000560 Citrus x paradisi Species 0.000 description 1
• 241000028397 Classiculomycetes Species 0.000 description 1
• 241000221760 Claviceps Species 0.000 description 1
• 241001646158 Claviceps africana Species 0.000 description 1
• 241000124232 Claviceps fusiformis Species 0.000 description 1
• 241000124224 Claviceps paspali Species 0.000 description 1
• 241000223203 Coccidioides Species 0.000 description 1
• 241000228437 Cochliobolus Species 0.000 description 1
• 235000013162 Cocos nucifera Nutrition 0.000 description 1
• 244000060011 Cocos nucifera Species 0.000 description 1
• 240000007154 Coffea arabica Species 0.000 description 1
• 241001526452 Coleosporiaceae Species 0.000 description 1
• 108010078777 Colistin Proteins 0.000 description 1
• 102000029816 Collagenase Human genes 0.000 description 1
• 108060005980 Collagenase Proteins 0.000 description 1
• 241001133184 Colletotrichum agaves Species 0.000 description 1
• 241000272201 Columbiformes Species 0.000 description 1
• 241001480521 Conidiobolus coronatus Species 0.000 description 1
• 241000293017 Conidiobolus incongruus Species 0.000 description 1
• 241000218631 Coniferophyta Species 0.000 description 1
• 241001600095 Coniophora puteana Species 0.000 description 1
• 239000005752 Copper oxychloride Substances 0.000 description 1
• 240000000491 Corchorus aestuans Species 0.000 description 1
• 235000011777 Corchorus aestuans Nutrition 0.000 description 1
• 235000010862 Corchorus capsularis Nutrition 0.000 description 1
• 240000009226 Corylus americana Species 0.000 description 1
• 235000001543 Corylus americana Nutrition 0.000 description 1
• 235000007466 Corylus avellana Nutrition 0.000 description 1
• 241000699800 Cricetinae Species 0.000 description 1
• 241000938605 Crocodylia Species 0.000 description 1
• 241001123579 Cronartiaceae Species 0.000 description 1
• 241001123528 Cronartium ribicola Species 0.000 description 1
• 208000006081 Cryptococcal meningitis Diseases 0.000 description 1
• 241001527609 Cryptococcus Species 0.000 description 1
• 241000694959 Cryptococcus sp. Species 0.000 description 1
• 241000028392 Cryptomycocolacomycetes Species 0.000 description 1
• 241001116394 Cryptosporella Species 0.000 description 1
• 241000219112 Cucumis Species 0.000 description 1
• 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 1
• 240000008067 Cucumis sativus Species 0.000 description 1
• 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 1
• 241000223208 Curvularia Species 0.000 description 1
• 241000223211 Curvularia lunata Species 0.000 description 1
• 241001634927 Cutaneotrichosporon mucoides Species 0.000 description 1
• 229920001651 Cyanoacrylate Polymers 0.000 description 1
• 239000005755 Cyflufenamid Substances 0.000 description 1
• 239000005756 Cymoxanil Substances 0.000 description 1
• 241000252233 Cyprinus carpio Species 0.000 description 1
• 239000005757 Cyproconazole Substances 0.000 description 1
• 239000005758 Cyprodinil Substances 0.000 description 1
• 102000005927 Cysteine Proteases Human genes 0.000 description 1
• 108010005843 Cysteine Proteases Proteins 0.000 description 1
• 241000028404 Cystobasidiomycetes Species 0.000 description 1
• 108090000695 Cytokines Proteins 0.000 description 1
• 102000004127 Cytokines Human genes 0.000 description 1
• FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
• FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
• 108020004414 DNA Proteins 0.000 description 1
• 230000007018 DNA scission Effects 0.000 description 1
• 241000762597 Dacrymycetes Species 0.000 description 1
• 235000002767 Daucus carota Nutrition 0.000 description 1
• 244000000626 Daucus carota Species 0.000 description 1
• 239000005644 Dazomet Substances 0.000 description 1
• 206010011985 Decubitus ulcer Diseases 0.000 description 1
• 239000004287 Dehydroacetic acid Substances 0.000 description 1
• FBMORZZOJSDNRQ-UHFFFAOYSA-N Demethoxy,B,HCl-Adriamycin Natural products C1C2C(=C)CCCC2(C)CC2(O)C1=C(C)C(=O)O2 FBMORZZOJSDNRQ-UHFFFAOYSA-N 0.000 description 1
• FMTDIUIBLCQGJB-UHFFFAOYSA-N Demethylchlortetracyclin Natural products C1C2C(O)C3=C(Cl)C=CC(O)=C3C(=O)C2=C(O)C2(O)C1C(N(C)C)C(O)=C(C(N)=O)C2=O FMTDIUIBLCQGJB-UHFFFAOYSA-N 0.000 description 1
• 102000016911 Deoxyribonucleases Human genes 0.000 description 1
• 108010053770 Deoxyribonucleases Proteins 0.000 description 1
• 229920002307 Dextran Polymers 0.000 description 1
• 206010056340 Diabetic ulcer Diseases 0.000 description 1
• 241000723298 Dicentrarchus labrax Species 0.000 description 1
• BXZVVICBKDXVGW-NKWVEPMBSA-N Didanosine Chemical compound O1[C@H](CO)CC[C@@H]1N1C(NC=NC2=O)=C2N=C1 BXZVVICBKDXVGW-NKWVEPMBSA-N 0.000 description 1
• 239000005760 Difenoconazole Substances 0.000 description 1
• 240000008570 Digitaria exilis Species 0.000 description 1
• IIUZTXTZRGLYTI-UHFFFAOYSA-N Dihydrogriseofulvin Natural products COC1CC(=O)CC(C)C11C(=O)C(C(OC)=CC(OC)=C2Cl)=C2O1 IIUZTXTZRGLYTI-UHFFFAOYSA-N 0.000 description 1
• HDWLUGYOLUHEMN-UHFFFAOYSA-N Dinobuton Chemical compound CCC(C)C1=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C1OC(=O)OC(C)C HDWLUGYOLUHEMN-UHFFFAOYSA-N 0.000 description 1
• 241000935924 Diplodia quercina Species 0.000 description 1
• 241000560922 Discula Species 0.000 description 1
• 206010013439 Disseminated cryptococcosis Diseases 0.000 description 1
• 239000005766 Dodine Substances 0.000 description 1
• 241001326550 Dothideomycetes Species 0.000 description 1
• XPOQHMRABVBWPR-UHFFFAOYSA-N Efavirenz Natural products O1C(=O)NC2=CC=C(Cl)C=C2C1(C(F)(F)F)C#CC1CC1 XPOQHMRABVBWPR-UHFFFAOYSA-N 0.000 description 1
• 241001568741 Elsinoe poinsettiae Species 0.000 description 1
• 241000596569 Encephalitozoon intestinalis Species 0.000 description 1
• 241001442406 Enterocytozoon bieneusi Species 0.000 description 1
• 241001480035 Epidermophyton Species 0.000 description 1
• 241001480036 Epidermophyton floccosum Species 0.000 description 1
• 239000005767 Epoxiconazole Substances 0.000 description 1
• 241000283086 Equidae Species 0.000 description 1
• DNVPQKQSNYMLRS-NXVQYWJNSA-N Ergosterol Natural products CC(C)[C@@H](C)C=C[C@H](C)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@H]3CC[C@]12C DNVPQKQSNYMLRS-NXVQYWJNSA-N 0.000 description 1
• 241001480059 Erysiphaceae Species 0.000 description 1
• 241000221785 Erysiphales Species 0.000 description 1
• 241000510928 Erysiphe necator Species 0.000 description 1
• 241000726794 Erysiphe syringae Species 0.000 description 1
• 241000588724 Escherichia coli Species 0.000 description 1
• 108700039887 Essential Genes Proteins 0.000 description 1
• 239000004258 Ethoxyquin Substances 0.000 description 1
• 239000005769 Etridiazole Substances 0.000 description 1
• 240000002395 Euphorbia pulcherrima Species 0.000 description 1
• 241000223682 Exophiala Species 0.000 description 1
• 235000009419 Fagopyrum esculentum Nutrition 0.000 description 1
• 240000008620 Fagopyrum esculentum Species 0.000 description 1
• 240000000731 Fagus sylvatica Species 0.000 description 1
• 235000010099 Fagus sylvatica Nutrition 0.000 description 1
• 241000282326 Felis catus Species 0.000 description 1
• 239000005774 Fenamidone Substances 0.000 description 1
• 239000005775 Fenbuconazole Substances 0.000 description 1
• 239000005776 Fenhexamid Substances 0.000 description 1
• 239000005778 Fenpropimorph Substances 0.000 description 1
• 241000449920 Fibroporia vaillantii Species 0.000 description 1
• 241000192125 Firmicutes Species 0.000 description 1
• 208000009531 Fissure in Ano Diseases 0.000 description 1
• 239000005780 Fluazinam Substances 0.000 description 1
• 239000005781 Fludioxonil Substances 0.000 description 1
• UUOUOERPONYGOS-CLCRDYEYSA-N Fluocinolone Chemical compound O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@]([C@H](O)C4)(O)C(=O)CO)[C@@H]4[C@@H]3C[C@H](F)C2=C1 UUOUOERPONYGOS-CLCRDYEYSA-N 0.000 description 1
• WJOHZNCJWYWUJD-IUGZLZTKSA-N Fluocinonide Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)COC(=O)C)[C@@]2(C)C[C@@H]1O WJOHZNCJWYWUJD-IUGZLZTKSA-N 0.000 description 1
• LXMQMMSGERCRSU-UHFFFAOYSA-N Fluotrimazole Chemical compound FC(F)(F)C1=CC=CC(C(C=2C=CC=CC=2)(C=2C=CC=CC=2)N2N=CN=C2)=C1 LXMQMMSGERCRSU-UHFFFAOYSA-N 0.000 description 1
• 239000005784 Fluoxastrobin Substances 0.000 description 1
• 239000005785 Fluquinconazole Substances 0.000 description 1
• 239000005786 Flutolanil Substances 0.000 description 1
• 239000005787 Flutriafol Substances 0.000 description 1
• 239000005788 Fluxapyroxad Substances 0.000 description 1
• 239000005789 Folpet Substances 0.000 description 1
• 235000019715 Fonio Nutrition 0.000 description 1
• 241001669595 Fonsecaea compacta Species 0.000 description 1
• 241000122864 Fonsecaea pedrosoi Species 0.000 description 1
• 239000005791 Fuberidazole Substances 0.000 description 1
• 208000014260 Fungal keratitis Diseases 0.000 description 1
• 208000004770 Fusariosis Diseases 0.000 description 1
• 241000223197 Fusarium lateritium Species 0.000 description 1
• 241000879841 Fusarium oxysporum f. cubense Species 0.000 description 1
• 241000223192 Fusarium sporotrichioides Species 0.000 description 1
• 241000414088 Fuscoporia contigua Species 0.000 description 1
• 241000276438 Gadus morhua Species 0.000 description 1
• 241000453701 Galactomyces candidum Species 0.000 description 1
• 241000287828 Gallus gallus Species 0.000 description 1
• 240000008397 Ganoderma lucidum Species 0.000 description 1
• 102000004878 Gelsolin Human genes 0.000 description 1
• 108090001064 Gelsolin Proteins 0.000 description 1
• 229930182566 Gentamicin Natural products 0.000 description 1
• CEAZRRDELHUEMR-URQXQFDESA-N Gentamicin Chemical compound O1[C@H](C(C)NC)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@@](C)(O)CO2)O)[C@H](N)C[C@@H]1N CEAZRRDELHUEMR-URQXQFDESA-N 0.000 description 1
• 241000557168 Geoglossomycetes Species 0.000 description 1
• 235000017388 Geotrichum candidum Nutrition 0.000 description 1
• 241001583501 Glomeromycetes Species 0.000 description 1
• 241001583499 Glomeromycotina Species 0.000 description 1
• 229920001503 Glucan Polymers 0.000 description 1
• 244000068988 Glycine max Species 0.000 description 1
• 241000593551 Gremmeniella abietina Species 0.000 description 1
• UXWOXTQWVMFRSE-UHFFFAOYSA-N Griseoviridin Natural products O=C1OC(C)CC=C(C(NCC=CC=CC(O)CC(O)C2)=O)SCC1NC(=O)C1=COC2=N1 UXWOXTQWVMFRSE-UHFFFAOYSA-N 0.000 description 1
• 241001516047 Gymnosporangium juniperi-virginianae Species 0.000 description 1
• YDNLKBDXQCHOTH-UHFFFAOYSA-N Halacrinate Chemical compound C1=CC=C2C(Cl)=CC(Br)=C(OC(=O)C=C)C2=N1 YDNLKBDXQCHOTH-UHFFFAOYSA-N 0.000 description 1
• MUQNGPZZQDCDFT-JNQJZLCISA-N Halcinonide Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H]3OC(C)(C)O[C@@]3(C(=O)CCl)[C@@]1(C)C[C@@H]2O MUQNGPZZQDCDFT-JNQJZLCISA-N 0.000 description 1
• 241000880419 Harpellales Species 0.000 description 1
• 244000020551 Helianthus annuus Species 0.000 description 1
• 235000003222 Helianthus annuus Nutrition 0.000 description 1
• 241001181532 Hemileia vastatrix Species 0.000 description 1
• 241000228404 Histoplasma capsulatum Species 0.000 description 1
• 241001354006 Histoplasma capsulatum var. duboisii Species 0.000 description 1
• 206010020144 Histoplasmosis disseminated Diseases 0.000 description 1
• 101000685323 Homo sapiens Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Proteins 0.000 description 1
• 101000611183 Homo sapiens Tumor necrosis factor Proteins 0.000 description 1
• 241000308514 Hortaea werneckii Species 0.000 description 1
• VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 1
• XQFRJNBWHJMXHO-RRKCRQDMSA-N IDUR Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(I)=C1 XQFRJNBWHJMXHO-RRKCRQDMSA-N 0.000 description 1
• 241000188250 Idas Species 0.000 description 1
• DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
• 239000005795 Imazalil Substances 0.000 description 1
• 206010062016 Immunosuppression Diseases 0.000 description 1
• 229930010555 Inosine Natural products 0.000 description 1
• UGQMRVRMYYASKQ-KQYNXXCUSA-N Inosine Chemical compound O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C2=NC=NC(O)=C2N=C1 UGQMRVRMYYASKQ-KQYNXXCUSA-N 0.000 description 1
• 108010014726 Interferon Type I Proteins 0.000 description 1
• 102000002227 Interferon Type I Human genes 0.000 description 1
• 108010074328 Interferon-gamma Proteins 0.000 description 1
• 102000008070 Interferon-gamma Human genes 0.000 description 1
• 108010002352 Interleukin-1 Proteins 0.000 description 1
• 108090001005 Interleukin-6 Proteins 0.000 description 1
• 108090001007 Interleukin-8 Proteins 0.000 description 1
• JUZNIMUFDBIJCM-ANEDZVCMSA-N Invanz Chemical compound O=C([C@H]1NC[C@H](C1)SC=1[C@H](C)[C@@H]2[C@H](C(N2C=1C(O)=O)=O)[C@H](O)C)NC1=CC=CC(C(O)=O)=C1 JUZNIMUFDBIJCM-ANEDZVCMSA-N 0.000 description 1
• 244000017020 Ipomoea batatas Species 0.000 description 1
• 235000002678 Ipomoea batatas Nutrition 0.000 description 1
• UETNIIAIRMUTSM-UHFFFAOYSA-N Jacareubin Natural products CC1(C)OC2=CC3Oc4c(O)c(O)ccc4C(=O)C3C(=C2C=C1)O UETNIIAIRMUTSM-UHFFFAOYSA-N 0.000 description 1
• KJHKTHWMRKYKJE-SUGCFTRWSA-N Kaletra Chemical compound N1([C@@H](C(C)C)C(=O)N[C@H](C[C@H](O)[C@H](CC=2C=CC=CC=2)NC(=O)COC=2C(=CC=CC=2C)C)CC=2C=CC=CC=2)CCCNC1=O KJHKTHWMRKYKJE-SUGCFTRWSA-N 0.000 description 1
• 238000002768 Kirby-Bauer method Methods 0.000 description 1
• PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 description 1
• 102000003855 L-lactate dehydrogenase Human genes 0.000 description 1
• 108700023483 L-lactate dehydrogenases Proteins 0.000 description 1
• 241000526687 Lacazia loboi Species 0.000 description 1
• GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
• 235000003228 Lactuca sativa Nutrition 0.000 description 1
• 240000008415 Lactuca sativa Species 0.000 description 1
• 235000014647 Lens culinaris subsp culinaris Nutrition 0.000 description 1
• 244000043158 Lens esculenta Species 0.000 description 1
• 241001330696 Leptosphaeria coniothyrium Species 0.000 description 1
• 241000228457 Leptosphaeria maculans Species 0.000 description 1
• 241001512709 Lessonia <stramenopiles> Species 0.000 description 1
• 241001260563 Lessonia nigrescens Species 0.000 description 1
• 240000007472 Leucaena leucocephala Species 0.000 description 1
• 235000010643 Leucaena leucocephala Nutrition 0.000 description 1
• 241000896221 Leveillula taurica Species 0.000 description 1
• GSDSWSVVBLHKDQ-JTQLQIEISA-N Levofloxacin Chemical compound C([C@@H](N1C2=C(C(C(C(O)=O)=C1)=O)C=C1F)C)OC2=C1N1CCN(C)CC1 GSDSWSVVBLHKDQ-JTQLQIEISA-N 0.000 description 1
• 241000209510 Liliopsida Species 0.000 description 1
• 108090001060 Lipase Proteins 0.000 description 1
• 102000004882 Lipase Human genes 0.000 description 1
• 239000004367 Lipase Substances 0.000 description 1
• 235000007688 Lycopersicon esculentum Nutrition 0.000 description 1
• 206010025323 Lymphomas Diseases 0.000 description 1
• 101150057104 MCIDAS gene Proteins 0.000 description 1
• WLLGXSLBOPFWQV-UHFFFAOYSA-N MGK 264 Chemical compound C1=CC2CC1C1C2C(=O)N(CC(CC)CCCC)C1=O WLLGXSLBOPFWQV-UHFFFAOYSA-N 0.000 description 1
• TYMRLRRVMHJFTF-UHFFFAOYSA-N Mafenide Chemical compound NCC1=CC=C(S(N)(=O)=O)C=C1 TYMRLRRVMHJFTF-UHFFFAOYSA-N 0.000 description 1
• 241000218922 Magnoliophyta Species 0.000 description 1
• 241001291474 Malassezia globosa Species 0.000 description 1
• 241001291477 Malassezia restricta Species 0.000 description 1
• 241000124008 Mammalia Species 0.000 description 1
• 239000005804 Mandipropamid Substances 0.000 description 1
• 235000014826 Mangifera indica Nutrition 0.000 description 1
• 240000007228 Mangifera indica Species 0.000 description 1
• 241001661269 Marssonina Species 0.000 description 1
• ZCAHBOURBFRXOT-UHFFFAOYSA-N Mecarbinzid Chemical compound C1=CC=C2N(C(=O)NCCSC)C(NC(=O)OC)=NC2=C1 ZCAHBOURBFRXOT-UHFFFAOYSA-N 0.000 description 1
• 241000375796 Medicopsis romeroi Species 0.000 description 1
• 241000221538 Melampsoraceae Species 0.000 description 1
• 206010027146 Melanoderma Diseases 0.000 description 1
• 241000276495 Melanogrammus aeglefinus Species 0.000 description 1
• 206010027209 Meningitis cryptococcal Diseases 0.000 description 1
• 206010027236 Meningitis fungal Diseases 0.000 description 1
• 239000005805 Mepanipyrim Substances 0.000 description 1
• 239000005806 Meptyldinocap Substances 0.000 description 1
• 241000790612 Meruliporia incrassata Species 0.000 description 1
• XOGTZOOQQBDUSI-UHFFFAOYSA-M Mesna Chemical compound [Na+].[O-]S(=O)(=O)CCS XOGTZOOQQBDUSI-UHFFFAOYSA-M 0.000 description 1
• 102000005741 Metalloproteases Human genes 0.000 description 1
• 108010006035 Metalloproteases Proteins 0.000 description 1
• 239000002169 Metam Substances 0.000 description 1
• 239000005868 Metconazole Substances 0.000 description 1
• AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 description 1
• MWCLLHOVUTZFKS-UHFFFAOYSA-N Methyl cyanoacrylate Chemical compound COC(=O)C(=C)C#N MWCLLHOVUTZFKS-UHFFFAOYSA-N 0.000 description 1
• 239000005810 Metrafenone Substances 0.000 description 1
• 241000352027 Microbotryomycetes Species 0.000 description 1
• 229920000168 Microcrystalline cellulose Polymers 0.000 description 1
• 241000243190 Microsporidia Species 0.000 description 1
• 241001480037 Microsporum Species 0.000 description 1
• 241001480000 Microsporum audouinii Species 0.000 description 1
• 241000893980 Microsporum canis Species 0.000 description 1
• 241000028512 Mixiomycetes Species 0.000 description 1
• 241001430197 Mollicutes Species 0.000 description 1
• 241001518731 Monilinia fructicola Species 0.000 description 1
• 241000760372 Monoblepharidomycetes Species 0.000 description 1
• 241001459558 Monographella nivalis Species 0.000 description 1
• 235000008708 Morus alba Nutrition 0.000 description 1
• 240000000249 Morus alba Species 0.000 description 1
• 206010028034 Mouth ulceration Diseases 0.000 description 1
• 206010028080 Mucocutaneous candidiasis Diseases 0.000 description 1
• 101100400378 Mus musculus Marveld2 gene Proteins 0.000 description 1
• 241000699670 Mus sp. Species 0.000 description 1
• 235000003805 Musa ABB Group Nutrition 0.000 description 1
• 235000018290 Musa x paradisiaca Nutrition 0.000 description 1
• 239000005811 Myclobutanil Substances 0.000 description 1
• FTCOKXNKPOUEFH-UHFFFAOYSA-N Myclozolin Chemical compound O=C1C(COC)(C)OC(=O)N1C1=CC(Cl)=CC(Cl)=C1 FTCOKXNKPOUEFH-UHFFFAOYSA-N 0.000 description 1
• 231100000678 Mycotoxin Toxicity 0.000 description 1
• 241000223251 Myrothecium Species 0.000 description 1
• 229930188031 Mytoxin Natural products 0.000 description 1
• KJHOZAZQWVKILO-UHFFFAOYSA-N N-(diaminomethylidene)-4-morpholinecarboximidamide Chemical compound NC(N)=NC(=N)N1CCOCC1 KJHOZAZQWVKILO-UHFFFAOYSA-N 0.000 description 1
• XFOXDUJCOHBXRC-UHFFFAOYSA-N N-Ethyl-N-methyl-4-(trifluoromethyl)-2-(3,4-dimethoxyphenyl)benzamide Chemical compound CCN(C)C(=O)C1=CC=C(C(F)(F)F)C=C1C1=CC=C(OC)C(OC)=C1 XFOXDUJCOHBXRC-UHFFFAOYSA-N 0.000 description 1
• MBBZMMPHUWSWHV-BDVNFPICSA-N N-methylglucamine Chemical compound CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO MBBZMMPHUWSWHV-BDVNFPICSA-N 0.000 description 1
• XQJQCBDIXRIYRP-UHFFFAOYSA-N N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1pyrazole-4-carboxamide Chemical compound FC(F)C1=NN(C)C=C1C(=O)NC1=CC=CC=C1C1C(C2CC2)C1 XQJQCBDIXRIYRP-UHFFFAOYSA-N 0.000 description 1
• 241000893976 Nannizzia gypsea Species 0.000 description 1
• DDUHZTYCFQRHIY-UHFFFAOYSA-N Negwer: 6874 Natural products COC1=CC(=O)CC(C)C11C(=O)C(C(OC)=CC(OC)=C2Cl)=C2O1 DDUHZTYCFQRHIY-UHFFFAOYSA-N 0.000 description 1
• 241001326536 Neolectomycetes Species 0.000 description 1
• 229930193140 Neomycin Natural products 0.000 description 1
• 241000556984 Neonectria galligena Species 0.000 description 1
• VJAWBEFMCIINFU-UHFFFAOYSA-N Nitrothal-isopropyl Chemical group CC(C)OC(=O)C1=CC(C(=O)OC(C)C)=CC([N+]([O-])=O)=C1 VJAWBEFMCIINFU-UHFFFAOYSA-N 0.000 description 1
• 101710163270 Nuclease Proteins 0.000 description 1
• 108091028043 Nucleic acid sequence Proteins 0.000 description 1
• 239000004677 Nylon Substances 0.000 description 1
• 206010030154 Oesophageal candidiasis Diseases 0.000 description 1
• 240000007817 Olea europaea Species 0.000 description 1
• 241001625088 Ophiognomonia clavigignenti-juglandacearum Species 0.000 description 1
• 208000001388 Opportunistic Infections Diseases 0.000 description 1
• 208000007117 Oral Ulcer Diseases 0.000 description 1
• 241000283973 Oryctolagus cuniculus Species 0.000 description 1
• 208000005141 Otitis Diseases 0.000 description 1
• ZCQWOFVYLHDMMC-UHFFFAOYSA-N Oxazole Chemical compound C1=COC=N1 ZCQWOFVYLHDMMC-UHFFFAOYSA-N 0.000 description 1
• YXLXNENXOJSQEI-UHFFFAOYSA-L Oxine-copper Chemical compound [Cu+2].C1=CN=C2C([O-])=CC=CC2=C1.C1=CN=C2C([O-])=CC=CC2=C1 YXLXNENXOJSQEI-UHFFFAOYSA-L 0.000 description 1
• 239000004100 Oxytetracycline Substances 0.000 description 1
• 239000002033 PVDF binder Substances 0.000 description 1
• 108020002230 Pancreatic Ribonuclease Proteins 0.000 description 1
• 102000016387 Pancreatic elastase Human genes 0.000 description 1
• 108010067372 Pancreatic elastase Proteins 0.000 description 1
• 102000005891 Pancreatic ribonuclease Human genes 0.000 description 1
• TYMABNNERDVXID-DLYFRVTGSA-N Panipenem Chemical compound C([C@@H]1[C@H](C(N1C=1C(O)=O)=O)[C@H](O)C)C=1S[C@H]1CCN(C(C)=N)C1 TYMABNNERDVXID-DLYFRVTGSA-N 0.000 description 1
• 241000526686 Paracoccidioides brasiliensis Species 0.000 description 1
• 235000000370 Passiflora edulis Nutrition 0.000 description 1
• 244000288157 Passiflora edulis Species 0.000 description 1
• JNTOCHDNEULJHD-UHFFFAOYSA-N Penciclovir Chemical compound N1C(N)=NC(=O)C2=C1N(CCC(CO)CO)C=N2 JNTOCHDNEULJHD-UHFFFAOYSA-N 0.000 description 1
• 239000005813 Penconazole Substances 0.000 description 1
• 239000005814 Pencycuron Substances 0.000 description 1
• 229930182555 Penicillin Natural products 0.000 description 1
• 229930195708 Penicillin V Natural products 0.000 description 1
• 244000271379 Penicillium camembertii Species 0.000 description 1
• 235000002245 Penicillium camembertii Nutrition 0.000 description 1
• 241000228150 Penicillium chrysogenum Species 0.000 description 1
• 241000228153 Penicillium citrinum Species 0.000 description 1
• 235000002233 Penicillium roqueforti Nutrition 0.000 description 1
• 241000864371 Penicillium viridicatum Species 0.000 description 1
• 239000005816 Penthiopyrad Substances 0.000 description 1
• 239000006002 Pepper Substances 0.000 description 1
• 102000057297 Pepsin A Human genes 0.000 description 1
• 108090000284 Pepsin A Proteins 0.000 description 1
• 208000005888 Periodontal Pocket Diseases 0.000 description 1
• 241000893212 Pestalotia Species 0.000 description 1
• 241000121875 Phaeoacremonium krajdenii Species 0.000 description 1
• 235000010627 Phaseolus vulgaris Nutrition 0.000 description 1
• 244000046052 Phaseolus vulgaris Species 0.000 description 1
• 241000286209 Phasianidae Species 0.000 description 1
• 241001531356 Phialophora verrucosa Species 0.000 description 1
• 241001480007 Phomopsis Species 0.000 description 1
• 241000425347 Phyla <beetle> Species 0.000 description 1
• 241000932914 Physalospora obtusa Species 0.000 description 1
• 241000233614 Phytophthora Species 0.000 description 1
• 241000218657 Picea Species 0.000 description 1
• 239000005818 Picoxystrobin Substances 0.000 description 1
• 241001326499 Piedraia hortae Species 0.000 description 1
• 235000016761 Piper aduncum Nutrition 0.000 description 1
• 240000003889 Piper guineense Species 0.000 description 1
• 235000017804 Piper guineense Nutrition 0.000 description 1
• 235000008184 Piper nigrum Nutrition 0.000 description 1
• VQDBNKDJNJQRDG-UHFFFAOYSA-N Pirbuterol Chemical compound CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=N1 VQDBNKDJNJQRDG-UHFFFAOYSA-N 0.000 description 1
• 235000010582 Pisum sativum Nutrition 0.000 description 1
• 240000004713 Pisum sativum Species 0.000 description 1
• 235000015266 Plantago major Nutrition 0.000 description 1
• 241001326528 Pneumocystidomycetes Species 0.000 description 1
• 241000142787 Pneumocystis jirovecii Species 0.000 description 1
• 241001337898 Podosphaera aphanis Species 0.000 description 1
• 241000896201 Podosphaera fusca Species 0.000 description 1
• 241001337928 Podosphaera leucotricha Species 0.000 description 1
• 208000005374 Poisoning Diseases 0.000 description 1
• 239000004696 Poly ether ether ketone Substances 0.000 description 1
• 239000004952 Polyamide Substances 0.000 description 1
• 239000002202 Polyethylene glycol Substances 0.000 description 1
• 108010093965 Polymyxin B Proteins 0.000 description 1
• 229930182764 Polyoxin Natural products 0.000 description 1
• 229920000491 Polyphenylsulfone Polymers 0.000 description 1
• 239000004743 Polypropylene Substances 0.000 description 1
• 239000004793 Polystyrene Substances 0.000 description 1
• ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
• 229920000153 Povidone-iodine Polymers 0.000 description 1
• 208000004210 Pressure Ulcer Diseases 0.000 description 1
• 239000005820 Prochloraz Substances 0.000 description 1
• 239000005821 Propamocarb Substances 0.000 description 1
• 239000005822 Propiconazole Substances 0.000 description 1
• 239000005824 Proquinazid Substances 0.000 description 1
• 239000005825 Prothioconazole Substances 0.000 description 1
• 235000010401 Prunus avium Nutrition 0.000 description 1
• 235000006029 Prunus persica var nucipersica Nutrition 0.000 description 1
• 235000006040 Prunus persica var persica Nutrition 0.000 description 1
• 244000017714 Prunus persica var. nucipersica Species 0.000 description 1
• 240000008296 Prunus serotina Species 0.000 description 1
• 235000014441 Prunus serotina Nutrition 0.000 description 1
• 241000087479 Pseudocercospora fijiensis Species 0.000 description 1
• 241000184297 Pseudocercospora musae Species 0.000 description 1
• 241000589755 Pseudomonas mendocina Species 0.000 description 1
• 241000589776 Pseudomonas putida Species 0.000 description 1
• 241000287530 Psittaciformes Species 0.000 description 1
• 241001123561 Puccinia coronata Species 0.000 description 1
• 241000221575 Pucciniaceae Species 0.000 description 1
• 241001262639 Pucciniastraceae Species 0.000 description 1
• 241001181515 Pucciniosiraceae Species 0.000 description 1
• 208000004430 Pulmonary Aspergillosis Diseases 0.000 description 1
• WTKZEGDFNFYCGP-UHFFFAOYSA-N Pyrazole Chemical compound C=1C=NNC=1 WTKZEGDFNFYCGP-UHFFFAOYSA-N 0.000 description 1
• OVZITGHGWBXFEA-UHFFFAOYSA-N Pyridinitril Chemical compound ClC1=NC(Cl)=C(C#N)C(C=2C=CC=CC=2)=C1C#N OVZITGHGWBXFEA-UHFFFAOYSA-N 0.000 description 1
• 239000005828 Pyrimethanil Substances 0.000 description 1
• CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 description 1
• 235000016977 Quercus suber Nutrition 0.000 description 1
• 240000008289 Quercus suber Species 0.000 description 1
• CDEWHBGYSWJUFP-UHFFFAOYSA-N Quinacetol sulfate Chemical compound OS(O)(=O)=O.C1=CC=C2C(C(=O)C)=CC=C(O)C2=N1.C1=CC=C2C(C(=O)C)=CC=C(O)C2=N1 CDEWHBGYSWJUFP-UHFFFAOYSA-N 0.000 description 1
• 239000005831 Quinoxyfen Substances 0.000 description 1
• 241001489455 Raveneliaceae Species 0.000 description 1
• 241000293824 Rhinosporidium seeberi Species 0.000 description 1
• 241000813090 Rhizoctonia solani Species 0.000 description 1
• IWUCXVSUMQZMFG-AFCXAGJDSA-N Ribavirin Chemical compound N1=C(C(=O)N)N=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](CO)O1 IWUCXVSUMQZMFG-AFCXAGJDSA-N 0.000 description 1
• 235000002357 Ribes grossularia Nutrition 0.000 description 1
• 244000171263 Ribes grossularia Species 0.000 description 1
• 240000001890 Ribes hudsonianum Species 0.000 description 1
• 235000016954 Ribes hudsonianum Nutrition 0.000 description 1
• 235000001466 Ribes nigrum Nutrition 0.000 description 1
• 235000002355 Ribes spicatum Nutrition 0.000 description 1
• 235000016897 Ribes triste Nutrition 0.000 description 1
• 235000004443 Ricinus communis Nutrition 0.000 description 1
• NCDNCNXCDXHOMX-UHFFFAOYSA-N Ritonavir Natural products C=1C=CC=CC=1CC(NC(=O)OCC=1SC=NC=1)C(O)CC(CC=1C=CC=CC=1)NC(=O)C(C(C)C)NC(=O)N(C)CC1=CSC(C(C)C)=N1 NCDNCNXCDXHOMX-UHFFFAOYSA-N 0.000 description 1
• 241001495449 Robinia pseudoacacia Species 0.000 description 1
• 241000220317 Rosa Species 0.000 description 1
• 240000007651 Rubus glaucus Species 0.000 description 1
• 235000011034 Rubus glaucus Nutrition 0.000 description 1
• 235000009122 Rubus idaeus Nutrition 0.000 description 1
• GBFLZEXEOZUWRN-VKHMYHEASA-N S-carboxymethyl-L-cysteine Chemical compound OC(=O)[C@@H](N)CSCC(O)=O GBFLZEXEOZUWRN-VKHMYHEASA-N 0.000 description 1
• 241000235342 Saccharomycetes Species 0.000 description 1
• 241000124033 Salix Species 0.000 description 1
• 241000277331 Salmonidae Species 0.000 description 1
• 241000019649 Sawadaea tulasnei Species 0.000 description 1
• 241000447727 Scabies Species 0.000 description 1
• 241001326539 Schizosaccharomycetes Species 0.000 description 1
• 239000005834 Sedaxane Substances 0.000 description 1
• GIIZNNXWQWCKIB-UHFFFAOYSA-N Serevent Chemical compound C1=C(O)C(CO)=CC(C(O)CNCCCCCCOCCCCC=2C=CC=CC=2)=C1 GIIZNNXWQWCKIB-UHFFFAOYSA-N 0.000 description 1
• 102000012479 Serine Proteases Human genes 0.000 description 1
• 108010022999 Serine Proteases Proteins 0.000 description 1
• 241001674251 Serpula lacrymans Species 0.000 description 1
• FOIXSVOLVBLSDH-UHFFFAOYSA-N Silver ion Chemical compound [Ag+] FOIXSVOLVBLSDH-UHFFFAOYSA-N 0.000 description 1
• 206010040943 Skin Ulcer Diseases 0.000 description 1
• 239000005708 Sodium hypochlorite Substances 0.000 description 1
• KSQXVLVXUFHGJQ-UHFFFAOYSA-M Sodium ortho-phenylphenate Chemical compound [Na+].[O-]C1=CC=CC=C1C1=CC=CC=C1 KSQXVLVXUFHGJQ-UHFFFAOYSA-M 0.000 description 1
• 240000003768 Solanum lycopersicum Species 0.000 description 1
• 244000061456 Solanum tuberosum Species 0.000 description 1
• 235000002595 Solanum tuberosum Nutrition 0.000 description 1
• 235000011684 Sorghum saccharatum Nutrition 0.000 description 1
• 241000530175 Sphaerophragmiaceae Species 0.000 description 1
• 239000005837 Spiroxamine Substances 0.000 description 1
• 235000009184 Spondias indica Nutrition 0.000 description 1
• 241000226724 Sporisorium scitamineum Species 0.000 description 1
• 241001149963 Sporothrix schenckii Species 0.000 description 1
• 241001279361 Stachybotrys Species 0.000 description 1
• 229920002472 Starch Polymers 0.000 description 1
• XNKLLVCARDGLGL-JGVFFNPUSA-N Stavudine Chemical compound O=C1NC(=O)C(C)=CN1[C@H]1C=C[C@@H](CO)O1 XNKLLVCARDGLGL-JGVFFNPUSA-N 0.000 description 1
• 229910000831 Steel Inorganic materials 0.000 description 1
• 229930182558 Sterol Natural products 0.000 description 1
• 108010012901 Succinate Dehydrogenase Proteins 0.000 description 1
• 102000019259 Succinate Dehydrogenase Human genes 0.000 description 1
• 102100023155 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Human genes 0.000 description 1
• CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
• 229930006000 Sucrose Natural products 0.000 description 1
• 241000282887 Suidae Species 0.000 description 1
• QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
• NHUHCSRWZMLRLA-UHFFFAOYSA-N Sulfisoxazole Chemical compound CC1=NOC(NS(=O)(=O)C=2C=CC(N)=CC=2)=C1C NHUHCSRWZMLRLA-UHFFFAOYSA-N 0.000 description 1
• NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
• 208000002847 Surgical Wound Diseases 0.000 description 1
• 241000736855 Syncephalastrum racemosum Species 0.000 description 1
• 241000827175 Synchytrium endobioticum Species 0.000 description 1
• 206010042938 Systemic candida Diseases 0.000 description 1
• 241001523006 Talaromyces marneffei Species 0.000 description 1
• 241001326537 Taphrinomycetes Species 0.000 description 1
• 241001634922 Tausonia pullulans Species 0.000 description 1
• 239000005839 Tebuconazole Substances 0.000 description 1
• 239000005840 Tetraconazole Substances 0.000 description 1
• 244000269722 Thea sinensis Species 0.000 description 1
• 235000009470 Theobroma cacao Nutrition 0.000 description 1
• 244000299461 Theobroma cacao Species 0.000 description 1
• RMMPZDDLWLALLJ-UHFFFAOYSA-N Thermophillin Chemical compound COC1=CC(=O)C(OC)=CC1=O RMMPZDDLWLALLJ-UHFFFAOYSA-N 0.000 description 1
• JZFICWYCTCCINF-UHFFFAOYSA-N Thiadiazin Chemical compound S=C1SC(C)NC(C)N1CCN1C(=S)SC(C)NC1C JZFICWYCTCCINF-UHFFFAOYSA-N 0.000 description 1
• WKDDRNSBRWANNC-UHFFFAOYSA-N Thienamycin Natural products C1C(SCCN)=C(C(O)=O)N2C(=O)C(C(O)C)C21 WKDDRNSBRWANNC-UHFFFAOYSA-N 0.000 description 1
• GNVMUORYQLCPJZ-UHFFFAOYSA-M Thiocarbamate Chemical compound NC([S-])=O GNVMUORYQLCPJZ-UHFFFAOYSA-M 0.000 description 1
• 241000306447 Thyronectria austroamericana Species 0.000 description 1
• 240000006909 Tilia x europaea Species 0.000 description 1
• 235000011941 Tilia x europaea Nutrition 0.000 description 1
• 241000722093 Tilletia caries Species 0.000 description 1
• 241000722096 Tilletia controversa Species 0.000 description 1
• 241000031845 Tilletia laevis Species 0.000 description 1
• YTGJWQPHMWSCST-UHFFFAOYSA-N Tiopronin Chemical compound CC(S)C(=O)NCC(O)=O YTGJWQPHMWSCST-UHFFFAOYSA-N 0.000 description 1
• 108010058907 Tiopronin Proteins 0.000 description 1
• SUJUHGSWHZTSEU-UHFFFAOYSA-N Tipranavir Natural products C1C(O)=C(C(CC)C=2C=C(NS(=O)(=O)C=3N=CC(=CC=3)C(F)(F)F)C=CC=2)C(=O)OC1(CCC)CCC1=CC=CC=C1 SUJUHGSWHZTSEU-UHFFFAOYSA-N 0.000 description 1
• RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
• 239000005845 Tolclofos-methyl Substances 0.000 description 1
• 229920001615 Tragacanth Polymers 0.000 description 1
• 241000009791 Tremellomycetes Species 0.000 description 1
• 239000005846 Triadimenol Substances 0.000 description 1
• 239000005847 Triazoxide Substances 0.000 description 1
• APQHKWPGGHMYKJ-UHFFFAOYSA-N Tributyltin oxide Chemical compound CCCC[Sn](CCCC)(CCCC)O[Sn](CCCC)(CCCC)CCCC APQHKWPGGHMYKJ-UHFFFAOYSA-N 0.000 description 1
• 241000223259 Trichoderma Species 0.000 description 1
• 241000893963 Trichophyton concentricum Species 0.000 description 1
• 241001459572 Trichophyton interdigitale Species 0.000 description 1
• 241001045770 Trichophyton mentagrophytes Species 0.000 description 1
• 241000223229 Trichophyton rubrum Species 0.000 description 1
• 241001480050 Trichophyton violaceum Species 0.000 description 1
• 241000223231 Trichosporon beigelii Species 0.000 description 1
• 206010053461 Trichosporon infection Diseases 0.000 description 1
• 241001673999 Trichosporon japonicum Species 0.000 description 1
• 241001634925 Trichosporon ovoides Species 0.000 description 1
• 241000601794 Trichothecium Species 0.000 description 1
• 239000005857 Trifloxystrobin Substances 0.000 description 1
• 239000005858 Triflumizole Substances 0.000 description 1
• 235000019714 Triticale Nutrition 0.000 description 1
• 239000005859 Triticonazole Substances 0.000 description 1
• GLNADSQYFUSGOU-GPTZEZBUSA-J Trypan blue Chemical compound [Na+].[Na+].[Na+].[Na+].C1=C(S([O-])(=O)=O)C=C2C=C(S([O-])(=O)=O)C(/N=N/C3=CC=C(C=C3C)C=3C=C(C(=CC=3)\N=N\C=3C(=CC4=CC(=CC(N)=C4C=3O)S([O-])(=O)=O)S([O-])(=O)=O)C)=C(O)C2=C1N GLNADSQYFUSGOU-GPTZEZBUSA-J 0.000 description 1
• 102000004142 Trypsin Human genes 0.000 description 1
• 108090000631 Trypsin Proteins 0.000 description 1
• 241000347388 Umbrina Species 0.000 description 1
• 241000221576 Uromyces Species 0.000 description 1
• 241001409548 Uropyxidaceae Species 0.000 description 1
• 241000221566 Ustilago Species 0.000 description 1
• 235000017606 Vaccinium vitis idaea Nutrition 0.000 description 1
• 244000077923 Vaccinium vitis idaea Species 0.000 description 1
• 229930195482 Validamycin Natural products 0.000 description 1
• 239000005860 Valifenalate Substances 0.000 description 1
• 208000000558 Varicose Ulcer Diseases 0.000 description 1
• 208000009470 Ventilator-Associated Pneumonia Diseases 0.000 description 1
• 241000317942 Venturia <ichneumonid wasp> Species 0.000 description 1
• 241001006642 Venturia pyrina Species 0.000 description 1
• 241000251539 Vertebrata <Metazoa> Species 0.000 description 1
• 241001264154 Verticimonosporium Species 0.000 description 1
• 235000009754 Vitis X bourquina Nutrition 0.000 description 1
• 235000012333 Vitis X labruscana Nutrition 0.000 description 1
• 240000006365 Vitis vinifera Species 0.000 description 1
• 235000014787 Vitis vinifera Nutrition 0.000 description 1
• 201000007096 Vulvovaginal Candidiasis Diseases 0.000 description 1
• 206010064899 Vulvovaginal mycotic infection Diseases 0.000 description 1
• 206010048038 Wound infection Diseases 0.000 description 1
• WREGKURFCTUGRC-POYBYMJQSA-N Zalcitabine Chemical compound O=C1N=C(N)C=CN1[C@@H]1O[C@H](CO)CC1 WREGKURFCTUGRC-POYBYMJQSA-N 0.000 description 1
• HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
• 241000758405 Zoopagomycotina Species 0.000 description 1
• 239000005863 Zoxamide Substances 0.000 description 1
• 206010061418 Zygomycosis Diseases 0.000 description 1
• FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 1
• GLWHPRRGGYLLRV-XLPZGREQSA-N [[(2s,3s,5r)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](N=[N+]=[N-])C1 GLWHPRRGGYLLRV-XLPZGREQSA-N 0.000 description 1
• MCGSCOLBFJQGHM-SCZZXKLOSA-N abacavir Chemical compound C=12N=CN([C@H]3C=C[C@@H](CO)C3)C2=NC(N)=NC=1NC1CC1 MCGSCOLBFJQGHM-SCZZXKLOSA-N 0.000 description 1
• 229960004748 abacavir Drugs 0.000 description 1
• DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 description 1
• 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 description 1
• 229960004308 acetylcysteine Drugs 0.000 description 1
• UVCFFGYNJOPUSF-UHFFFAOYSA-M acetyloxy(ethyl)mercury Chemical compound CC[Hg+].CC([O-])=O UVCFFGYNJOPUSF-UHFFFAOYSA-M 0.000 description 1
• CGIHPACLZJDCBQ-UHFFFAOYSA-N acibenzolar Chemical compound SC(=O)C1=CC=CC2=C1SN=N2 CGIHPACLZJDCBQ-UHFFFAOYSA-N 0.000 description 1
• 229960004150 aciclovir Drugs 0.000 description 1
• MKUXAQIIEYXACX-UHFFFAOYSA-N aciclovir Chemical compound N1C(N)=NC(=O)C2=C1N(COCCO)C=N2 MKUXAQIIEYXACX-UHFFFAOYSA-N 0.000 description 1
• XECAHXYUAAWDEL-UHFFFAOYSA-N acrylonitrile butadiene styrene Chemical compound C=CC=C.C=CC#N.C=CC1=CC=CC=C1 XECAHXYUAAWDEL-UHFFFAOYSA-N 0.000 description 1
• 239000004480 active ingredient Substances 0.000 description 1
• 125000004442 acylamino group Chemical group 0.000 description 1
• 230000000996 additive effect Effects 0.000 description 1
• 229960001997 adefovir Drugs 0.000 description 1
• WOZSCQDILHKSGG-UHFFFAOYSA-N adefovir depivoxil Chemical compound N1=CN=C2N(CCOCP(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C)C=NC2=C1N WOZSCQDILHKSGG-UHFFFAOYSA-N 0.000 description 1
• 239000000853 adhesive Substances 0.000 description 1
• 230000001070 adhesive effect Effects 0.000 description 1
• 230000002411 adverse Effects 0.000 description 1
• 239000005409 aflatoxin Substances 0.000 description 1
• 239000000556 agonist Substances 0.000 description 1
• 235000013334 alcoholic beverage Nutrition 0.000 description 1
• 150000001298 alcohols Chemical class 0.000 description 1
• 150000001299 aldehydes Chemical class 0.000 description 1
• 239000000783 alginic acid Substances 0.000 description 1
• 229960001126 alginic acid Drugs 0.000 description 1
• 150000004781 alginic acids Chemical class 0.000 description 1
• 229930013930 alkaloid Natural products 0.000 description 1
• 150000003797 alkaloid derivatives Chemical class 0.000 description 1
• 150000008055 alkyl aryl sulfonates Chemical class 0.000 description 1
• 125000000217 alkyl group Chemical group 0.000 description 1
• 208000006778 allergic bronchopulmonary aspergillosis Diseases 0.000 description 1
• 230000000172 allergic effect Effects 0.000 description 1
• JDLKFOPOAOFWQN-UHFFFAOYSA-N allicin Chemical compound C=CCSS(=O)CC=C JDLKFOPOAOFWQN-UHFFFAOYSA-N 0.000 description 1
• 235000010081 allicin Nutrition 0.000 description 1
• 239000000956 alloy Substances 0.000 description 1
• 229910045601 alloy Inorganic materials 0.000 description 1
• 235000020224 almond Nutrition 0.000 description 1
• TUFPZQHDPZYIEX-UHFFFAOYSA-N alpha-Santonin Natural products C1CC2(C)C=CC(=O)C=C2C2C1C(C)C(=O)O2 TUFPZQHDPZYIEX-UHFFFAOYSA-N 0.000 description 1
• XJHDMGJURBVLLE-BOCCBSBMSA-N alpha-santonin Chemical compound C([C@]1(C)CC2)=CC(=O)C(C)=C1[C@@H]1[C@@H]2[C@H](C)C(=O)O1 XJHDMGJURBVLLE-BOCCBSBMSA-N 0.000 description 1
• 229910052782 aluminium Inorganic materials 0.000 description 1
• XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
• DKNWSYNQZKUICI-UHFFFAOYSA-N amantadine Chemical compound C1C(C2)CC3CC2CC1(N)C3 DKNWSYNQZKUICI-UHFFFAOYSA-N 0.000 description 1
• 229960003805 amantadine Drugs 0.000 description 1
• 229960005174 ambroxol Drugs 0.000 description 1
• JBDGDEWWOUBZPM-XYPYZODXSA-N ambroxol Chemical compound NC1=C(Br)C=C(Br)C=C1CN[C@@H]1CC[C@@H](O)CC1 JBDGDEWWOUBZPM-XYPYZODXSA-N 0.000 description 1
• ILKJAFIWWBXGDU-MOGDOJJUSA-N amcinonide Chemical compound O([C@@]1([C@H](O2)C[C@@H]3[C@@]1(C[C@H](O)[C@]1(F)[C@@]4(C)C=CC(=O)C=C4CC[C@H]13)C)C(=O)COC(=O)C)C12CCCC1 ILKJAFIWWBXGDU-MOGDOJJUSA-N 0.000 description 1
• 229960003099 amcinonide Drugs 0.000 description 1
• 150000001408 amides Chemical class 0.000 description 1
• 229960004821 amikacin Drugs 0.000 description 1
• LKCWBDHBTVXHDL-RMDFUYIESA-N amikacin Chemical compound O([C@@H]1[C@@H](N)C[C@H]([C@@H]([C@H]1O)O[C@@H]1[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O1)O)NC(=O)[C@@H](O)CCN)[C@H]1O[C@H](CN)[C@@H](O)[C@H](O)[C@H]1O LKCWBDHBTVXHDL-RMDFUYIESA-N 0.000 description 1
• 229940126575 aminoglycoside Drugs 0.000 description 1
• FROZIYRKKUFAOC-UHFFFAOYSA-N amobam Chemical compound N.N.SC(=S)NCCNC(S)=S FROZIYRKKUFAOC-UHFFFAOYSA-N 0.000 description 1
• 229960003022 amoxicillin Drugs 0.000 description 1
• LSQZJLSUYDQPKJ-NJBDSQKTSA-N amoxicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=C(O)C=C1 LSQZJLSUYDQPKJ-NJBDSQKTSA-N 0.000 description 1
• 239000002280 amphoteric surfactant Substances 0.000 description 1
• 229960000723 ampicillin Drugs 0.000 description 1
• AVKUERGKIZMTKX-NJBDSQKTSA-N ampicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=CC=C1 AVKUERGKIZMTKX-NJBDSQKTSA-N 0.000 description 1
• YMARZQAQMVYCKC-OEMFJLHTSA-N amprenavir Chemical compound C([C@@H]([C@H](O)CN(CC(C)C)S(=O)(=O)C=1C=CC(N)=CC=1)NC(=O)O[C@@H]1COCC1)C1=CC=CC=C1 YMARZQAQMVYCKC-OEMFJLHTSA-N 0.000 description 1
• 229960001830 amprenavir Drugs 0.000 description 1
• IMHBYKMAHXWHRP-UHFFFAOYSA-N anilazine Chemical compound ClC1=CC=CC=C1NC1=NC(Cl)=NC(Cl)=N1 IMHBYKMAHXWHRP-UHFFFAOYSA-N 0.000 description 1
• 238000010171 animal model Methods 0.000 description 1
• 230000001078 anti-cholinergic effect Effects 0.000 description 1
• 230000000840 anti-viral effect Effects 0.000 description 1
• 229940065524 anticholinergics inhalants for obstructive airway diseases Drugs 0.000 description 1
• CQIUKKVOEOPUDV-IYSWYEEDSA-N antimycin Chemical compound OC1=C(C(O)=O)C(=O)C(C)=C2[C@H](C)[C@@H](C)OC=C21 CQIUKKVOEOPUDV-IYSWYEEDSA-N 0.000 description 1
• 239000003963 antioxidant agent Substances 0.000 description 1
• 235000006708 antioxidants Nutrition 0.000 description 1
• 230000001640 apoptogenic effect Effects 0.000 description 1
• 239000007864 aqueous solution Substances 0.000 description 1
• 239000008135 aqueous vehicle Substances 0.000 description 1
• ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 1
• 229910052785 arsenic Inorganic materials 0.000 description 1
• RQNWIZPPADIBDY-UHFFFAOYSA-N arsenic atom Chemical compound [As] RQNWIZPPADIBDY-UHFFFAOYSA-N 0.000 description 1
• 125000003118 aryl group Chemical group 0.000 description 1
• AXRYRYVKAWYZBR-GASGPIRDSA-N atazanavir Chemical compound C([C@H](NC(=O)[C@@H](NC(=O)OC)C(C)(C)C)[C@@H](O)CN(CC=1C=CC(=CC=1)C=1N=CC=CC=1)NC(=O)[C@@H](NC(=O)OC)C(C)(C)C)C1=CC=CC=C1 AXRYRYVKAWYZBR-GASGPIRDSA-N 0.000 description 1
• 229960003277 atazanavir Drugs 0.000 description 1
• QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
• 208000010668 atopic eczema Diseases 0.000 description 1
• 229940068561 atripla Drugs 0.000 description 1
• AKNQMEBLVAMSNZ-UHFFFAOYSA-N azaconazole Chemical compound ClC1=CC(Cl)=CC=C1C1(CN2N=CN=C2)OCCO1 AKNQMEBLVAMSNZ-UHFFFAOYSA-N 0.000 description 1
• 229950000294 azaconazole Drugs 0.000 description 1
• HFRHTRKMBOQLLL-UHFFFAOYSA-N azane;diethoxy-sulfanyl-sulfanylidene-$l^{5}-phosphane Chemical compound [NH4+].CCOP([S-])(=S)OCC HFRHTRKMBOQLLL-UHFFFAOYSA-N 0.000 description 1
• 229960004099 azithromycin Drugs 0.000 description 1
• MQTOSJVFKKJCRP-BICOPXKESA-N azithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)N(C)C[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 MQTOSJVFKKJCRP-BICOPXKESA-N 0.000 description 1
• 150000003851 azoles Chemical class 0.000 description 1
• WZPBZJONDBGPKJ-VEHQQRBSSA-N aztreonam Chemical compound O=C1N(S([O-])(=O)=O)[C@@H](C)[C@@H]1NC(=O)C(=N/OC(C)(C)C(O)=O)\C1=CSC([NH3+])=N1 WZPBZJONDBGPKJ-VEHQQRBSSA-N 0.000 description 1
• 229960003644 aztreonam Drugs 0.000 description 1
• 229960003071 bacitracin Drugs 0.000 description 1
• 229930184125 bacitracin Natural products 0.000 description 1
• CLKOFPXJLQSYAH-ABRJDSQDSA-N bacitracin A Chemical compound C1SC([C@@H](N)[C@@H](C)CC)=N[C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]1C(=O)N[C@H](CCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2N=CNC=2)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCC1 CLKOFPXJLQSYAH-ABRJDSQDSA-N 0.000 description 1
• 229910052788 barium Inorganic materials 0.000 description 1
• DSAJWYNOEDNPEQ-UHFFFAOYSA-N barium atom Chemical compound [Ba] DSAJWYNOEDNPEQ-UHFFFAOYSA-N 0.000 description 1
• 210000004082 barrier epithelial cell Anatomy 0.000 description 1
• 229940092705 beclomethasone Drugs 0.000 description 1
• NBMKJKDGKREAPL-DVTGEIKXSA-N beclomethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O NBMKJKDGKREAPL-DVTGEIKXSA-N 0.000 description 1
• 235000015278 beef Nutrition 0.000 description 1
• 230000008901 benefit Effects 0.000 description 1
• ZVSKZLHKADLHSD-UHFFFAOYSA-N benzanilide Chemical compound C=1C=CC=CC=1C(=O)NC1=CC=CC=C1 ZVSKZLHKADLHSD-UHFFFAOYSA-N 0.000 description 1
• VDEUYMSGMPQMIK-UHFFFAOYSA-N benzhydroxamic acid Chemical compound ONC(=O)C1=CC=CC=C1 VDEUYMSGMPQMIK-UHFFFAOYSA-N 0.000 description 1
• WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 1
• 229940124748 beta 2 agonist Drugs 0.000 description 1
• 102000015736 beta 2-Microglobulin Human genes 0.000 description 1
• 108010081355 beta 2-Microglobulin Proteins 0.000 description 1
• 229940125388 beta agonist Drugs 0.000 description 1
• 229960002537 betamethasone Drugs 0.000 description 1
• UREBDLICKHMUKA-DVTGEIKXSA-N betamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-DVTGEIKXSA-N 0.000 description 1
• 229950007599 betamipron Drugs 0.000 description 1
• 229960003169 biapenem Drugs 0.000 description 1
• MRMBZHPJVKCOMA-YJFSRANCSA-N biapenem Chemical compound C1N2C=NC=[N+]2CC1SC([C@@H]1C)=C(C([O-])=O)N2[C@H]1[C@@H]([C@H](O)C)C2=O MRMBZHPJVKCOMA-YJFSRANCSA-N 0.000 description 1
• 239000003613 bile acid Substances 0.000 description 1
• 239000000227 bioadhesive Substances 0.000 description 1
• 239000013060 biological fluid Substances 0.000 description 1
• 230000001851 biosynthetic effect Effects 0.000 description 1
• 125000006267 biphenyl group Chemical group 0.000 description 1
• JFIOVJDNOJYLKP-UHFFFAOYSA-N bithionol Chemical compound OC1=C(Cl)C=C(Cl)C=C1SC1=CC(Cl)=CC(Cl)=C1O JFIOVJDNOJYLKP-UHFFFAOYSA-N 0.000 description 1
• 229960002326 bithionol Drugs 0.000 description 1
• CXNPLSGKWMLZPZ-UHFFFAOYSA-N blasticidin-S Natural products O1C(C(O)=O)C(NC(=O)CC(N)CCN(C)C(N)=N)C=CC1N1C(=O)N=C(N)C=C1 CXNPLSGKWMLZPZ-UHFFFAOYSA-N 0.000 description 1
• 239000007844 bleaching agent Substances 0.000 description 1
• 208000002352 blister Diseases 0.000 description 1
• 239000006161 blood agar Substances 0.000 description 1
• LHHCSNFAOIFYRV-DOVBMPENSA-N boceprevir Chemical compound O=C([C@@H]1[C@@H]2[C@@H](C2(C)C)CN1C(=O)[C@@H](NC(=O)NC(C)(C)C)C(C)(C)C)NC(C(=O)C(N)=O)CC1CCC1 LHHCSNFAOIFYRV-DOVBMPENSA-N 0.000 description 1
• 229960000517 boceprevir Drugs 0.000 description 1
• 210000001185 bone marrow Anatomy 0.000 description 1
• BWUIOGHGUVLNSX-UHFFFAOYSA-M bromo(3-ethoxypropyl)mercury Chemical compound CCOCCC[Hg]Br BWUIOGHGUVLNSX-UHFFFAOYSA-M 0.000 description 1
• HJJVPARKXDDIQD-UHFFFAOYSA-N bromuconazole Chemical compound ClC1=CC(Cl)=CC=C1C1(CN2N=CN=C2)OCC(Br)C1 HJJVPARKXDDIQD-UHFFFAOYSA-N 0.000 description 1
• 239000000872 buffer Substances 0.000 description 1
• NTXGQCSETZTARF-UHFFFAOYSA-N buta-1,3-diene;prop-2-enenitrile Chemical compound C=CC=C.C=CC#N NTXGQCSETZTARF-UHFFFAOYSA-N 0.000 description 1
• PPKJUHVNTMYXOD-PZGPJMECSA-N c49ws9n75l Chemical compound O=C([C@@H]1N(C2=O)CC[C@H]1S(=O)(=O)CCN(CC)CC)O[C@H](C(C)C)[C@H](C)\C=C\C(=O)NC\C=C\C(\C)=C\[C@@H](O)CC(=O)CC1=NC2=CO1.N([C@@H]1C(=O)N[C@@H](C(N2CCC[C@H]2C(=O)N(C)[C@@H](CC=2C=CC(=CC=2)N(C)C)C(=O)N2C[C@@H](CS[C@H]3C4CCN(CC4)C3)C(=O)C[C@H]2C(=O)N[C@H](C(=O)O[C@@H]1C)C=1C=CC=CC=1)=O)CC)C(=O)C1=NC=CC=C1O PPKJUHVNTMYXOD-PZGPJMECSA-N 0.000 description 1
• 239000011575 calcium Substances 0.000 description 1
• 229910052791 calcium Inorganic materials 0.000 description 1
• 239000001506 calcium phosphate Substances 0.000 description 1
• 229910000389 calcium phosphate Inorganic materials 0.000 description 1
• 235000011010 calcium phosphates Nutrition 0.000 description 1
• 239000000378 calcium silicate Substances 0.000 description 1
• 229910052918 calcium silicate Inorganic materials 0.000 description 1
• 229960003340 calcium silicate Drugs 0.000 description 1
• 235000012241 calcium silicate Nutrition 0.000 description 1
• OYACROKNLOSFPA-UHFFFAOYSA-N calcium;dioxido(oxo)silane Chemical compound [Ca+2].[O-][Si]([O-])=O OYACROKNLOSFPA-UHFFFAOYSA-N 0.000 description 1
• BPKIGYQJPYCAOW-FFJTTWKXSA-I calcium;potassium;disodium;(2s)-2-hydroxypropanoate;dichloride;dihydroxide;hydrate Chemical compound O.[OH-].[OH-].[Na+].[Na+].[Cl-].[Cl-].[K+].[Ca+2].C[C@H](O)C([O-])=O BPKIGYQJPYCAOW-FFJTTWKXSA-I 0.000 description 1
• BMLSTPRTEKLIPM-UHFFFAOYSA-I calcium;potassium;disodium;hydrogen carbonate;dichloride;dihydroxide;hydrate Chemical compound O.[OH-].[OH-].[Na+].[Na+].[Cl-].[Cl-].[K+].[Ca+2].OC([O-])=O BMLSTPRTEKLIPM-UHFFFAOYSA-I 0.000 description 1
• 229940041514 candida albicans extract Drugs 0.000 description 1
• JHRWWRDRBPCWTF-OLQVQODUSA-N captafol Chemical compound C1C=CC[C@H]2C(=O)N(SC(Cl)(Cl)C(Cl)Cl)C(=O)[C@H]21 JHRWWRDRBPCWTF-OLQVQODUSA-N 0.000 description 1
• 229940117949 captan Drugs 0.000 description 1
• 239000004202 carbamide Substances 0.000 description 1
• 229940041011 carbapenems Drugs 0.000 description 1
• 229960003669 carbenicillin Drugs 0.000 description 1
• FPPNZSSZRUTDAP-UWFZAAFLSA-N carbenicillin Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)C(C(O)=O)C1=CC=CC=C1 FPPNZSSZRUTDAP-UWFZAAFLSA-N 0.000 description 1
• 229960004399 carbocisteine Drugs 0.000 description 1
• 239000001569 carbon dioxide Substances 0.000 description 1
• 229910002092 carbon dioxide Inorganic materials 0.000 description 1
• RXDMAYSSBPYBFW-PKFCDNJMSA-N carpropamide Chemical compound N([C@@H](C)C=1C=CC(Cl)=CC=1)C(=O)[C@@]1(CC)[C@H](C)C1(Cl)Cl RXDMAYSSBPYBFW-PKFCDNJMSA-N 0.000 description 1
• 239000000969 carrier Substances 0.000 description 1
• HHTWOMMSBMNRKP-UHFFFAOYSA-N carvacrol Natural products CC(=C)C1=CC=C(C)C(O)=C1 HHTWOMMSBMNRKP-UHFFFAOYSA-N 0.000 description 1
• RECUKUPTGUEGMW-UHFFFAOYSA-N carvacrol Chemical compound CC(C)C1=CC=C(C)C(O)=C1 RECUKUPTGUEGMW-UHFFFAOYSA-N 0.000 description 1
• 235000007746 carvacrol Nutrition 0.000 description 1
• 235000020226 cashew nut Nutrition 0.000 description 1
• 230000015556 catabolic process Effects 0.000 description 1
• 150000001768 cations Chemical class 0.000 description 1
• 229960005361 cefaclor Drugs 0.000 description 1
• QYIYFLOTGYLRGG-GPCCPHFNSA-N cefaclor Chemical compound C1([C@H](C(=O)N[C@@H]2C(N3C(=C(Cl)CS[C@@H]32)C(O)=O)=O)N)=CC=CC=C1 QYIYFLOTGYLRGG-GPCCPHFNSA-N 0.000 description 1
• 229960003012 cefamandole Drugs 0.000 description 1
• OLVCFLKTBJRLHI-AXAPSJFSSA-N cefamandole Chemical compound CN1N=NN=C1SCC1=C(C(O)=O)N2C(=O)[C@@H](NC(=O)[C@H](O)C=3C=CC=CC=3)[C@H]2SC1 OLVCFLKTBJRLHI-AXAPSJFSSA-N 0.000 description 1
• 229960001139 cefazolin Drugs 0.000 description 1
• MLYYVTUWGNIJIB-BXKDBHETSA-N cefazolin Chemical compound S1C(C)=NN=C1SCC1=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CN3N=NN=C3)[C@H]2SC1 MLYYVTUWGNIJIB-BXKDBHETSA-N 0.000 description 1
• 229960003719 cefdinir Drugs 0.000 description 1
• RTXOFQZKPXMALH-GHXIOONMSA-N cefdinir Chemical compound S1C(N)=NC(C(=N\O)\C(=O)N[C@@H]2C(N3C(=C(C=C)CS[C@@H]32)C(O)=O)=O)=C1 RTXOFQZKPXMALH-GHXIOONMSA-N 0.000 description 1
• 229960004069 cefditoren Drugs 0.000 description 1
• KMIPKYQIOVAHOP-YLGJWRNMSA-N cefditoren Chemical compound S([C@@H]1[C@@H](C(N1C=1C(O)=O)=O)NC(=O)\C(=N/OC)C=2N=C(N)SC=2)CC=1\C=C/C=1SC=NC=1C KMIPKYQIOVAHOP-YLGJWRNMSA-N 0.000 description 1
• 229960002100 cefepime Drugs 0.000 description 1
• HVFLCNVBZFFHBT-ZKDACBOMSA-O cefepime(1+) Chemical compound S([C@@H]1[C@@H](C(N1C=1C(O)=O)=O)NC(=O)\C(=N/OC)C=2N=C(N)SC=2)CC=1C[N+]1(C)CCCC1 HVFLCNVBZFFHBT-ZKDACBOMSA-O 0.000 description 1
• 229960002129 cefixime Drugs 0.000 description 1
• OKBVVJOGVLARMR-QSWIMTSFSA-N cefixime Chemical compound S1C(N)=NC(C(=N\OCC(O)=O)\C(=O)N[C@@H]2C(N3C(=C(C=C)CS[C@@H]32)C(O)=O)=O)=C1 OKBVVJOGVLARMR-QSWIMTSFSA-N 0.000 description 1
• 229960004682 cefoperazone Drugs 0.000 description 1
• GCFBRXLSHGKWDP-XCGNWRKASA-N cefoperazone Chemical compound O=C1C(=O)N(CC)CCN1C(=O)N[C@H](C=1C=CC(O)=CC=1)C(=O)N[C@@H]1C(=O)N2C(C(O)=O)=C(CSC=3N(N=NN=3)C)CS[C@@H]21 GCFBRXLSHGKWDP-XCGNWRKASA-N 0.000 description 1
• 229960004261 cefotaxime Drugs 0.000 description 1
• AZZMGZXNTDTSME-JUZDKLSSSA-M cefotaxime sodium Chemical compound [Na+].N([C@@H]1C(N2C(=C(COC(C)=O)CS[C@@H]21)C([O-])=O)=O)C(=O)\C(=N/OC)C1=CSC(N)=N1 AZZMGZXNTDTSME-JUZDKLSSSA-M 0.000 description 1
• 229960002682 cefoxitin Drugs 0.000 description 1
• 229960005090 cefpodoxime Drugs 0.000 description 1
• WYUSVOMTXWRGEK-HBWVYFAYSA-N cefpodoxime Chemical compound N([C@H]1[C@@H]2N(C1=O)C(=C(CS2)COC)C(O)=O)C(=O)C(=N/OC)\C1=CSC(N)=N1 WYUSVOMTXWRGEK-HBWVYFAYSA-N 0.000 description 1
• 229960002580 cefprozil Drugs 0.000 description 1
• 229960000484 ceftazidime Drugs 0.000 description 1
• NMVPEQXCMGEDNH-TZVUEUGBSA-N ceftazidime pentahydrate Chemical compound O.O.O.O.O.S([C@@H]1[C@@H](C(N1C=1C([O-])=O)=O)NC(=O)\C(=N/OC(C)(C)C(O)=O)C=2N=C(N)SC=2)CC=1C[N+]1=CC=CC=C1 NMVPEQXCMGEDNH-TZVUEUGBSA-N 0.000 description 1
• 229960004086 ceftibuten Drugs 0.000 description 1
• UNJFKXSSGBWRBZ-BJCIPQKHSA-N ceftibuten Chemical compound S1C(N)=NC(C(=C\CC(O)=O)\C(=O)N[C@@H]2C(N3C(=CCS[C@@H]32)C(O)=O)=O)=C1 UNJFKXSSGBWRBZ-BJCIPQKHSA-N 0.000 description 1
• 229960001991 ceftizoxime Drugs 0.000 description 1
• NNULBSISHYWZJU-LLKWHZGFSA-N ceftizoxime Chemical compound N([C@@H]1C(N2C(=CCS[C@@H]21)C(O)=O)=O)C(=O)\C(=N/OC)C1=CSC(N)=N1 NNULBSISHYWZJU-LLKWHZGFSA-N 0.000 description 1
• 229960004755 ceftriaxone Drugs 0.000 description 1
• VAAUVRVFOQPIGI-SPQHTLEESA-N ceftriaxone Chemical compound S([C@@H]1[C@@H](C(N1C=1C(O)=O)=O)NC(=O)\C(=N/OC)C=2N=C(N)SC=2)CC=1CSC1=NC(=O)C(=O)NN1C VAAUVRVFOQPIGI-SPQHTLEESA-N 0.000 description 1
• 229960001668 cefuroxime Drugs 0.000 description 1
• JFPVXVDWJQMJEE-IZRZKJBUSA-N cefuroxime Chemical compound N([C@@H]1C(N2C(=C(COC(N)=O)CS[C@@H]21)C(O)=O)=O)C(=O)\C(=N/OC)C1=CC=CO1 JFPVXVDWJQMJEE-IZRZKJBUSA-N 0.000 description 1
• 210000005056 cell body Anatomy 0.000 description 1
• 230000032823 cell division Effects 0.000 description 1
• 230000003915 cell function Effects 0.000 description 1
• 230000003833 cell viability Effects 0.000 description 1
• 230000002490 cerebral effect Effects 0.000 description 1
• 210000003679 cervix uteri Anatomy 0.000 description 1
• 229960001927 cetylpyridinium chloride Drugs 0.000 description 1
• YMKDRGPMQRFJGP-UHFFFAOYSA-M cetylpyridinium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1 YMKDRGPMQRFJGP-UHFFFAOYSA-M 0.000 description 1
• 230000008859 change Effects 0.000 description 1
• MYPYJXKWCTUITO-KIIOPKALSA-N chembl3301825 Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)C(O)[C@H](C)O1 MYPYJXKWCTUITO-KIIOPKALSA-N 0.000 description 1
• 239000013043 chemical agent Substances 0.000 description 1
• 150000005829 chemical entities Chemical class 0.000 description 1
• 230000007073 chemical hydrolysis Effects 0.000 description 1
• 238000007385 chemical modification Methods 0.000 description 1
• 238000006243 chemical reaction Methods 0.000 description 1
• 230000000973 chemotherapeutic effect Effects 0.000 description 1
• 235000013330 chicken meat Nutrition 0.000 description 1
• 229960005091 chloramphenicol Drugs 0.000 description 1
• WIIZWVCIJKGZOK-RKDXNWHRSA-N chloramphenicol Chemical compound ClC(Cl)C(=O)N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1 WIIZWVCIJKGZOK-RKDXNWHRSA-N 0.000 description 1
• HKMOPYJWSFRURD-UHFFFAOYSA-N chloro hypochlorite;copper Chemical compound [Cu].ClOCl HKMOPYJWSFRURD-UHFFFAOYSA-N 0.000 description 1
• VJTAZCKMHINUKO-UHFFFAOYSA-M chloro(2-methoxyethyl)mercury Chemical compound [Cl-].COCC[Hg+] VJTAZCKMHINUKO-UHFFFAOYSA-M 0.000 description 1
• PFIADAMVCJPXSF-UHFFFAOYSA-N chloroneb Chemical compound COC1=CC(Cl)=C(OC)C=C1Cl PFIADAMVCJPXSF-UHFFFAOYSA-N 0.000 description 1
• LFHISGNCFUNFFM-UHFFFAOYSA-N chloropicrin Chemical compound [O-][N+](=O)C(Cl)(Cl)Cl LFHISGNCFUNFFM-UHFFFAOYSA-N 0.000 description 1
• CRQQGFGUEAVUIL-UHFFFAOYSA-N chlorothalonil Chemical compound ClC1=C(Cl)C(C#N)=C(Cl)C(C#N)=C1Cl CRQQGFGUEAVUIL-UHFFFAOYSA-N 0.000 description 1
• NHTGQOXRZFUGJX-UHFFFAOYSA-N chlorquinox Chemical compound N1=CC=NC2=C(Cl)C(Cl)=C(Cl)C(Cl)=C21 NHTGQOXRZFUGJX-UHFFFAOYSA-N 0.000 description 1
• 239000000812 cholinergic antagonist Substances 0.000 description 1
• 238000004587 chromatography analysis Methods 0.000 description 1
• 229910052804 chromium Inorganic materials 0.000 description 1
• 239000011651 chromium Substances 0.000 description 1
• 229960003749 ciclopirox Drugs 0.000 description 1
• 229960000724 cidofovir Drugs 0.000 description 1
• 210000004081 cilia Anatomy 0.000 description 1
• 229960003405 ciprofloxacin Drugs 0.000 description 1
• CQIUKKVOEOPUDV-UHFFFAOYSA-N citrinine Natural products OC1=C(C(O)=O)C(=O)C(C)=C2C(C)C(C)OC=C21 CQIUKKVOEOPUDV-UHFFFAOYSA-N 0.000 description 1
• 229960002626 clarithromycin Drugs 0.000 description 1
• AGOYDEPGAOXOCK-KCBOHYOISA-N clarithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@](C)([C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)OC)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 AGOYDEPGAOXOCK-KCBOHYOISA-N 0.000 description 1
• 239000012459 cleaning agent Substances 0.000 description 1
• 229960001117 clenbuterol Drugs 0.000 description 1
• STJMRWALKKWQGH-UHFFFAOYSA-N clenbuterol Chemical compound CC(C)(C)NCC(O)C1=CC(Cl)=C(N)C(Cl)=C1 STJMRWALKKWQGH-UHFFFAOYSA-N 0.000 description 1
• 229960003344 climbazole Drugs 0.000 description 1
• 229960002227 clindamycin Drugs 0.000 description 1
• KDLRVYVGXIQJDK-AWPVFWJPSA-N clindamycin Chemical compound CN1C[C@H](CCC)C[C@H]1C(=O)N[C@H]([C@H](C)Cl)[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@@H](SC)O1 KDLRVYVGXIQJDK-AWPVFWJPSA-N 0.000 description 1
• 230000007012 clinical effect Effects 0.000 description 1
• 229960002842 clobetasol Drugs 0.000 description 1
• FCSHDIVRCWTZOX-DVTGEIKXSA-N clobetasol Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CCl)(O)[C@@]1(C)C[C@@H]2O FCSHDIVRCWTZOX-DVTGEIKXSA-N 0.000 description 1
• 229960001146 clobetasone Drugs 0.000 description 1
• XXIFVOHLGBURIG-OZCCCYNHSA-N clobetasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CCl)(O)[C@@]1(C)CC2=O XXIFVOHLGBURIG-OZCCCYNHSA-N 0.000 description 1
• 229960003326 cloxacillin Drugs 0.000 description 1
• LQOLIRLGBULYKD-JKIFEVAISA-N cloxacillin Chemical compound N([C@@H]1C(N2[C@H](C(C)(C)S[C@@H]21)C(O)=O)=O)C(=O)C1=C(C)ON=C1C1=CC=CC=C1Cl LQOLIRLGBULYKD-JKIFEVAISA-N 0.000 description 1
• 229940047766 co-trimoxazole Drugs 0.000 description 1
• 239000008199 coating composition Substances 0.000 description 1
• 235000016213 coffee Nutrition 0.000 description 1
• 235000013353 coffee beverage Nutrition 0.000 description 1
• 229960003346 colistin Drugs 0.000 description 1
• 229960002424 collagenase Drugs 0.000 description 1
• 239000008119 colloidal silica Substances 0.000 description 1
• 238000002648 combination therapy Methods 0.000 description 1
• 230000007748 combinatorial effect Effects 0.000 description 1
• 229940014461 combivir Drugs 0.000 description 1
• 238000009833 condensation Methods 0.000 description 1
• 230000005494 condensation Effects 0.000 description 1
• 235000013409 condiments Nutrition 0.000 description 1
• 235000009508 confectionery Nutrition 0.000 description 1
• 239000004035 construction material Substances 0.000 description 1
• 239000012050 conventional carrier Substances 0.000 description 1
• 238000007796 conventional method Methods 0.000 description 1
• 229920001577 copolymer Polymers 0.000 description 1
• 229940116318 copper carbonate Drugs 0.000 description 1
• 229940120693 copper naphthenate Drugs 0.000 description 1
• BERDEBHAJNAUOM-UHFFFAOYSA-N copper(I) oxide Inorganic materials [Cu]O[Cu] BERDEBHAJNAUOM-UHFFFAOYSA-N 0.000 description 1
• OPQARKPSCNTWTJ-UHFFFAOYSA-L copper(ii) acetate Chemical compound [Cu+2].CC([O-])=O.CC([O-])=O OPQARKPSCNTWTJ-UHFFFAOYSA-L 0.000 description 1
• SVOAENZIOKPANY-CVBJKYQLSA-L copper;(z)-octadec-9-enoate Chemical compound [Cu+2].CCCCCCCC\C=C/CCCCCCCC([O-])=O.CCCCCCCC\C=C/CCCCCCCC([O-])=O SVOAENZIOKPANY-CVBJKYQLSA-L 0.000 description 1
• SEVNKWFHTNVOLD-UHFFFAOYSA-L copper;3-(4-ethylcyclohexyl)propanoate;3-(3-ethylcyclopentyl)propanoate Chemical compound [Cu+2].CCC1CCC(CCC([O-])=O)C1.CCC1CCC(CCC([O-])=O)CC1 SEVNKWFHTNVOLD-UHFFFAOYSA-L 0.000 description 1
• GEZOTWYUIKXWOA-UHFFFAOYSA-L copper;carbonate Chemical compound [Cu+2].[O-]C([O-])=O GEZOTWYUIKXWOA-UHFFFAOYSA-L 0.000 description 1
• ZZBBCSFCMKWYQR-UHFFFAOYSA-N copper;dioxido(oxo)silane Chemical compound [Cu+2].[O-][Si]([O-])=O ZZBBCSFCMKWYQR-UHFFFAOYSA-N 0.000 description 1
• CWVRPJSBNHNJSI-XQNSMLJCSA-N coumoxystrobin Chemical compound C1=C2OC(=O)C(CCCC)=C(C)C2=CC=C1OCC1=CC=CC=C1\C(=C/OC)C(=O)OC CWVRPJSBNHNJSI-XQNSMLJCSA-N 0.000 description 1
• 239000006071 cream Substances 0.000 description 1
• 229940013361 cresol Drugs 0.000 description 1
• 244000038559 crop plants Species 0.000 description 1
• 229940112669 cuprous oxide Drugs 0.000 description 1
• KRFJLUBVMFXRPN-UHFFFAOYSA-N cuprous oxide Chemical compound [O-2].[Cu+].[Cu+] KRFJLUBVMFXRPN-UHFFFAOYSA-N 0.000 description 1
• 238000009109 curative therapy Methods 0.000 description 1
• 208000005035 cutaneous candidiasis Diseases 0.000 description 1
• 201000009861 cutaneous mycosis Diseases 0.000 description 1
• 125000004122 cyclic group Chemical group 0.000 description 1
• ACMXQHFNODYQAT-UHFFFAOYSA-N cyflufenamid Chemical compound FC1=CC=C(C(F)(F)F)C(C(NOCC2CC2)=NC(=O)CC=2C=CC=CC=2)=C1F ACMXQHFNODYQAT-UHFFFAOYSA-N 0.000 description 1
• HAORKNGNJCEJBX-UHFFFAOYSA-N cyprodinil Chemical compound N=1C(C)=CC(C2CC2)=NC=1NC1=CC=CC=C1 HAORKNGNJCEJBX-UHFFFAOYSA-N 0.000 description 1
• 230000009089 cytolysis Effects 0.000 description 1
• 210000000805 cytoplasm Anatomy 0.000 description 1
• 235000013365 dairy product Nutrition 0.000 description 1
• CJBJHOAVZSMMDJ-HEXNFIEUSA-N darunavir Chemical compound C([C@@H]([C@H](O)CN(CC(C)C)S(=O)(=O)C=1C=CC(N)=CC=1)NC(=O)O[C@@H]1[C@@H]2CCO[C@@H]2OC1)C1=CC=CC=C1 CJBJHOAVZSMMDJ-HEXNFIEUSA-N 0.000 description 1
• 229960005107 darunavir Drugs 0.000 description 1
• QAYICIQNSGETAS-UHFFFAOYSA-N dazomet Chemical compound CN1CSC(=S)N(C)C1 QAYICIQNSGETAS-UHFFFAOYSA-N 0.000 description 1
• 238000000354 decomposition reaction Methods 0.000 description 1
• 238000005202 decontamination Methods 0.000 description 1
• 230000003588 decontaminative effect Effects 0.000 description 1
• 230000000593 degrading effect Effects 0.000 description 1
• 235000019258 dehydroacetic acid Nutrition 0.000 description 1
• 229940061632 dehydroacetic acid Drugs 0.000 description 1
• JEQRBTDTEKWZBW-UHFFFAOYSA-N dehydroacetic acid Chemical compound CC(=O)C1=C(O)OC(C)=CC1=O JEQRBTDTEKWZBW-UHFFFAOYSA-N 0.000 description 1
• PGRHXDWITVMQBC-UHFFFAOYSA-N dehydroacetic acid Natural products CC(=O)C1C(=O)OC(C)=CC1=O PGRHXDWITVMQBC-UHFFFAOYSA-N 0.000 description 1
• 229960005319 delavirdine Drugs 0.000 description 1
• 230000001934 delay Effects 0.000 description 1
• 229960002398 demeclocycline Drugs 0.000 description 1
• 239000004053 dental implant Substances 0.000 description 1
• 239000002781 deodorant agent Substances 0.000 description 1
• 230000000779 depleting effect Effects 0.000 description 1
• 229960003662 desonide Drugs 0.000 description 1
• WBGKWQHBNHJJPZ-LECWWXJVSA-N desonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O WBGKWQHBNHJJPZ-LECWWXJVSA-N 0.000 description 1
• 230000001066 destructive effect Effects 0.000 description 1
• 229960003957 dexamethasone Drugs 0.000 description 1
• UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 description 1
• 239000008355 dextrose injection Substances 0.000 description 1
• 206010012601 diabetes mellitus Diseases 0.000 description 1
• WURGXGVFSMYFCG-UHFFFAOYSA-N dichlofluanid Chemical compound CN(C)S(=O)(=O)N(SC(F)(Cl)Cl)C1=CC=CC=C1 WURGXGVFSMYFCG-UHFFFAOYSA-N 0.000 description 1
• BIXZHMJUSMUDOQ-UHFFFAOYSA-N dichloran Chemical compound NC1=C(Cl)C=C([N+]([O-])=O)C=C1Cl BIXZHMJUSMUDOQ-UHFFFAOYSA-N 0.000 description 1
• YEJGPFZQLRMXOI-PKEIRNPWSA-N diclocymet Chemical compound N#CC(C(C)(C)C)C(=O)N[C@H](C)C1=CC=C(Cl)C=C1Cl YEJGPFZQLRMXOI-PKEIRNPWSA-N 0.000 description 1
• UWQMKVBQKFHLCE-UHFFFAOYSA-N diclomezine Chemical compound C1=C(Cl)C(C)=C(Cl)C=C1C1=NNC(=O)C=C1 UWQMKVBQKFHLCE-UHFFFAOYSA-N 0.000 description 1
• 229960001585 dicloxacillin Drugs 0.000 description 1
• YFAGHNZHGGCZAX-JKIFEVAISA-N dicloxacillin Chemical compound N([C@@H]1C(N2[C@H](C(C)(C)S[C@@H]21)C(O)=O)=O)C(=O)C1=C(C)ON=C1C1=C(Cl)C=CC=C1Cl YFAGHNZHGGCZAX-JKIFEVAISA-N 0.000 description 1
• 229960002656 didanosine Drugs 0.000 description 1
• 235000014113 dietary fatty acids Nutrition 0.000 description 1
• FFYPMLJYZAEMQB-UHFFFAOYSA-N diethyl pyrocarbonate Chemical compound CCOC(=O)OC(=O)OCC FFYPMLJYZAEMQB-UHFFFAOYSA-N 0.000 description 1
• BQYJATMQXGBDHF-UHFFFAOYSA-N difenoconazole Chemical compound O1C(C)COC1(C=1C(=CC(OC=2C=CC(Cl)=CC=2)=CC=1)Cl)CN1N=CN=C1 BQYJATMQXGBDHF-UHFFFAOYSA-N 0.000 description 1
• CJHXCRMKMMBYJQ-UHFFFAOYSA-N dimethirimol Chemical compound CCCCC1=C(C)NC(N(C)C)=NC1=O CJHXCRMKMMBYJQ-UHFFFAOYSA-N 0.000 description 1
• ZHIKKPYAYGUYPV-UHFFFAOYSA-N dimethylaminocarbamothioylsulfanyl n-(dimethylamino)carbamodithioate Chemical compound CN(C)NC(=S)SSC(=S)NN(C)C ZHIKKPYAYGUYPV-UHFFFAOYSA-N 0.000 description 1
• 229940035422 diphenylamine Drugs 0.000 description 1
• 229960004100 dirithromycin Drugs 0.000 description 1
• WLOHNSSYAXHWNR-NXPDYKKBSA-N dirithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H]2O[C@H](COCCOC)N[C@H]([C@@H]2C)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 WLOHNSSYAXHWNR-NXPDYKKBSA-N 0.000 description 1
• 208000022682 disseminated sporotrichosis Diseases 0.000 description 1
• 229960002563 disulfiram Drugs 0.000 description 1
• PYZSVQVRHDXQSL-UHFFFAOYSA-N dithianon Chemical compound S1C(C#N)=C(C#N)SC2=C1C(=O)C1=CC=CC=C1C2=O PYZSVQVRHDXQSL-UHFFFAOYSA-N 0.000 description 1
• 229960000735 docosanol Drugs 0.000 description 1
• 229960001700 domiodol Drugs 0.000 description 1
• NEIPZWZQHXCYDV-UHFFFAOYSA-N domiodol Chemical compound OCC1COC(CI)O1 NEIPZWZQHXCYDV-UHFFFAOYSA-N 0.000 description 1
• 229960000895 doripenem Drugs 0.000 description 1
• AVAACINZEOAHHE-VFZPANTDSA-N doripenem Chemical compound C=1([C@H](C)[C@@H]2[C@H](C(N2C=1C(O)=O)=O)[C@H](O)C)S[C@@H]1CN[C@H](CNS(N)(=O)=O)C1 AVAACINZEOAHHE-VFZPANTDSA-N 0.000 description 1
• 231100000673 dose–response relationship Toxicity 0.000 description 1
• 229960003722 doxycycline Drugs 0.000 description 1
• 238000012377 drug delivery Methods 0.000 description 1
• 230000004064 dysfunction Effects 0.000 description 1
• 208000019258 ear infection Diseases 0.000 description 1
• AWZOLILCOUMRDG-UHFFFAOYSA-N edifenphos Chemical compound C=1C=CC=CC=1SP(=O)(OCC)SC1=CC=CC=C1 AWZOLILCOUMRDG-UHFFFAOYSA-N 0.000 description 1
• 229960002030 edoxudine Drugs 0.000 description 1
• XACKNLSZYYIACO-DJLDLDEBSA-N edoxudine Chemical compound O=C1NC(=O)C(CC)=CN1[C@@H]1O[C@H](CO)[C@@H](O)C1 XACKNLSZYYIACO-DJLDLDEBSA-N 0.000 description 1
• 229960003804 efavirenz Drugs 0.000 description 1
• XPOQHMRABVBWPR-ZDUSSCGKSA-N efavirenz Chemical compound C([C@]1(C2=CC(Cl)=CC=C2NC(=O)O1)C(F)(F)F)#CC1CC1 XPOQHMRABVBWPR-ZDUSSCGKSA-N 0.000 description 1
• 230000005611 electricity Effects 0.000 description 1
• 239000003995 emulsifying agent Substances 0.000 description 1
• 206010014665 endocarditis Diseases 0.000 description 1
• 229960002125 enilconazole Drugs 0.000 description 1
• 229960002549 enoxacin Drugs 0.000 description 1
• IDYZIJYBMGIQMJ-UHFFFAOYSA-N enoxacin Chemical compound N1=C2N(CC)C=C(C(O)=O)C(=O)C2=CC(F)=C1N1CCNCC1 IDYZIJYBMGIQMJ-UHFFFAOYSA-N 0.000 description 1
• VMNULHCTRPXWFJ-UJSVPXBISA-N enoxastrobin Chemical compound CO\C=C(\C(=O)OC)C1=CC=CC=C1CO\N=C(/C)\C=C\C1=CC=C(Cl)C=C1 VMNULHCTRPXWFJ-UJSVPXBISA-N 0.000 description 1
• 230000007071 enzymatic hydrolysis Effects 0.000 description 1
• 238000006047 enzymatic hydrolysis reaction Methods 0.000 description 1
• 229960005139 epinephrine Drugs 0.000 description 1
• YJGVMLPVUAXIQN-UHFFFAOYSA-N epipodophyllotoxin Natural products COC1=C(OC)C(OC)=CC(C2C3=CC=4OCOC=4C=C3C(O)C3C2C(OC3)=O)=C1 YJGVMLPVUAXIQN-UHFFFAOYSA-N 0.000 description 1
• 229960002561 eprazinone Drugs 0.000 description 1
• BSHWLCACYCVCJE-UHFFFAOYSA-N eprazinone Chemical compound C=1C=CC=CC=1C(OCC)CN(CC1)CCN1CC(C)C(=O)C1=CC=CC=C1 BSHWLCACYCVCJE-UHFFFAOYSA-N 0.000 description 1
• QNQBPPQLRODXET-UHFFFAOYSA-N equisetin Natural products CC=CC1C=CC2CC(C)CCC2C1(C)C(O)=C1C(=O)C(CO)N(C)C1=O QNQBPPQLRODXET-UHFFFAOYSA-N 0.000 description 1
• 230000008029 eradication Effects 0.000 description 1
• DNVPQKQSNYMLRS-SOWFXMKYSA-N ergosterol Chemical compound C1[C@@H](O)CC[C@]2(C)[C@H](CC[C@]3([C@H]([C@H](C)/C=C/[C@@H](C)C(C)C)CC[C@H]33)C)C3=CC=C21 DNVPQKQSNYMLRS-SOWFXMKYSA-N 0.000 description 1
• 230000008686 ergosterol biosynthesis Effects 0.000 description 1
• 229960002770 ertapenem Drugs 0.000 description 1
• 229960003276 erythromycin Drugs 0.000 description 1
• 201000005655 esophageal candidiasis Diseases 0.000 description 1
• 150000002148 esters Chemical class 0.000 description 1
• 229960000285 ethambutol Drugs 0.000 description 1
• DECIPOUIJURFOJ-UHFFFAOYSA-N ethoxyquin Chemical compound N1C(C)(C)C=C(C)C2=CC(OCC)=CC=C21 DECIPOUIJURFOJ-UHFFFAOYSA-N 0.000 description 1
• 229940093500 ethoxyquin Drugs 0.000 description 1
• 235000019285 ethoxyquin Nutrition 0.000 description 1
• IGUYEXXAGBDLLX-UHFFFAOYSA-N ethyl 3-(3,5-dichlorophenyl)-5-methyl-2,4-dioxo-1,3-oxazolidine-5-carboxylate Chemical compound O=C1C(C(=O)OCC)(C)OC(=O)N1C1=CC(Cl)=CC(Cl)=C1 IGUYEXXAGBDLLX-UHFFFAOYSA-N 0.000 description 1
• ZHCJUZJGMJDUKJ-UHFFFAOYSA-M ethyl(phosphonatooxy)mercury;hydron Chemical compound CC[Hg+].OP(O)([O-])=O ZHCJUZJGMJDUKJ-UHFFFAOYSA-M 0.000 description 1
• KQTVWCSONPJJPE-UHFFFAOYSA-N etridiazole Chemical compound CCOC1=NC(C(Cl)(Cl)Cl)=NS1 KQTVWCSONPJJPE-UHFFFAOYSA-N 0.000 description 1
• 241001233957 eudicotyledons Species 0.000 description 1
• 239000003172 expectorant agent Substances 0.000 description 1
• 239000000284 extract Substances 0.000 description 1
• 210000003414 extremity Anatomy 0.000 description 1
• 210000000744 eyelid Anatomy 0.000 description 1
• 239000000194 fatty acid Substances 0.000 description 1
• 229930195729 fatty acid Natural products 0.000 description 1
• 150000004665 fatty acids Chemical class 0.000 description 1
• LMVPQMGRYSRMIW-KRWDZBQOSA-N fenamidone Chemical compound O=C([C@@](C)(N=C1SC)C=2C=CC=CC=2)N1NC1=CC=CC=C1 LMVPQMGRYSRMIW-KRWDZBQOSA-N 0.000 description 1
• RBWGTZRSEOIHFD-UHUFKFKFSA-N fenaminstrobin Chemical compound CNC(=O)C(=N\OC)\C1=CC=CC=C1CO\N=C(/C)\C=C\C1=C(Cl)C=CC=C1Cl RBWGTZRSEOIHFD-UHUFKFKFSA-N 0.000 description 1
• JFSPBVWPKOEZCB-UHFFFAOYSA-N fenfuram Chemical compound O1C=CC(C(=O)NC=2C=CC=CC=2)=C1C JFSPBVWPKOEZCB-UHFFFAOYSA-N 0.000 description 1
• VDLGAVXLJYLFDH-UHFFFAOYSA-N fenhexamid Chemical compound C=1C=C(O)C(Cl)=C(Cl)C=1NC(=O)C1(C)CCCCC1 VDLGAVXLJYLFDH-UHFFFAOYSA-N 0.000 description 1
• FKLFBQCQQYDUAM-UHFFFAOYSA-N fenpiclonil Chemical compound ClC1=CC=CC(C=2C(=CNC=2)C#N)=C1Cl FKLFBQCQQYDUAM-UHFFFAOYSA-N 0.000 description 1
• WHDGWKAJBYRJJL-UHFFFAOYSA-K ferbam Chemical compound [Fe+3].CN(C)C([S-])=S.CN(C)C([S-])=S.CN(C)C([S-])=S WHDGWKAJBYRJJL-UHFFFAOYSA-K 0.000 description 1
• GOWLARCWZRESHU-AQTBWJFISA-N ferimzone Chemical compound C=1C=CC=C(C)C=1C(/C)=N\NC1=NC(C)=CC(C)=N1 GOWLARCWZRESHU-AQTBWJFISA-N 0.000 description 1
• 239000003337 fertilizer Substances 0.000 description 1
• 238000001914 filtration Methods 0.000 description 1
• 239000000796 flavoring agent Substances 0.000 description 1
• 238000007667 floating Methods 0.000 description 1
• UZCGKGPEKUCDTF-UHFFFAOYSA-N fluazinam Chemical compound [O-][N+](=O)C1=CC(C(F)(F)F)=C(Cl)C([N+]([O-])=O)=C1NC1=NC=C(C(F)(F)F)C=C1Cl UZCGKGPEKUCDTF-UHFFFAOYSA-N 0.000 description 1
• MUJOIMFVNIBMKC-UHFFFAOYSA-N fludioxonil Chemical compound C=12OC(F)(F)OC2=CC=CC=1C1=CNC=C1C#N MUJOIMFVNIBMKC-UHFFFAOYSA-N 0.000 description 1
• 229960000676 flunisolide Drugs 0.000 description 1
• 229940043075 fluocinolone Drugs 0.000 description 1
• 229960000785 fluocinonide Drugs 0.000 description 1
• 229960003973 fluocortolone Drugs 0.000 description 1
• GAKMQHDJQHZUTJ-ULHLPKEOSA-N fluocortolone Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@@H]1[C@@H]2[C@@H]2C[C@@H](C)[C@H](C(=O)CO)[C@@]2(C)C[C@@H]1O GAKMQHDJQHZUTJ-ULHLPKEOSA-N 0.000 description 1
• 239000007850 fluorescent dye Substances 0.000 description 1
• UFEODZBUAFNAEU-NLRVBDNBSA-N fluoxastrobin Chemical compound C=1C=CC=C(OC=2C(=C(OC=3C(=CC=CC=3)Cl)N=CN=2)F)C=1C(=N/OC)\C1=NOCCO1 UFEODZBUAFNAEU-NLRVBDNBSA-N 0.000 description 1
• 229960003238 fluprednidene Drugs 0.000 description 1
• YVHXHNGGPURVOS-SBTDHBFYSA-N fluprednidene Chemical compound O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@](C(=C)C4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 YVHXHNGGPURVOS-SBTDHBFYSA-N 0.000 description 1
• IJJVMEJXYNJXOJ-UHFFFAOYSA-N fluquinconazole Chemical compound C=1C=C(Cl)C=C(Cl)C=1N1C(=O)C2=CC(F)=CC=C2N=C1N1C=NC=N1 IJJVMEJXYNJXOJ-UHFFFAOYSA-N 0.000 description 1
• FQKUGOMFVDPBIZ-UHFFFAOYSA-N flusilazole Chemical compound C=1C=C(F)C=CC=1[Si](C=1C=CC(F)=CC=1)(C)CN1C=NC=N1 FQKUGOMFVDPBIZ-UHFFFAOYSA-N 0.000 description 1
• GNVDAZSPJWCIQZ-UHFFFAOYSA-N flusulfamide Chemical compound ClC1=CC([N+](=O)[O-])=CC=C1NS(=O)(=O)C1=CC=C(Cl)C(C(F)(F)F)=C1 GNVDAZSPJWCIQZ-UHFFFAOYSA-N 0.000 description 1
• 229960002714 fluticasone Drugs 0.000 description 1
• MGNNYOODZCAHBA-GQKYHHCASA-N fluticasone Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@@H](C)[C@@](C(=O)SCF)(O)[C@@]2(C)C[C@@H]1O MGNNYOODZCAHBA-GQKYHHCASA-N 0.000 description 1
• PTCGDEVVHUXTMP-UHFFFAOYSA-N flutolanil Chemical compound CC(C)OC1=CC=CC(NC(=O)C=2C(=CC=CC=2)C(F)(F)F)=C1 PTCGDEVVHUXTMP-UHFFFAOYSA-N 0.000 description 1
• SXSGXWCSHSVPGB-UHFFFAOYSA-N fluxapyroxad Chemical compound FC(F)C1=NN(C)C=C1C(=O)NC1=CC=CC=C1C1=CC(F)=C(F)C(F)=C1 SXSGXWCSHSVPGB-UHFFFAOYSA-N 0.000 description 1
• HKIOYBQGHSTUDB-UHFFFAOYSA-N folpet Chemical compound C1=CC=C2C(=O)N(SC(Cl)(Cl)Cl)C(=O)C2=C1 HKIOYBQGHSTUDB-UHFFFAOYSA-N 0.000 description 1
• 229960001447 fomivirsen Drugs 0.000 description 1
• XCWFZHPEARLXJI-UHFFFAOYSA-N fomivirsen Chemical compound C1C(N2C3=C(C(NC(N)=N3)=O)N=C2)OC(CO)C1OP(O)(=S)OCC1OC(N(C)C(=O)\N=C(\N)C=C)CC1OP(O)(=S)OCC1OC(N2C3=C(C(NC(N)=N3)=O)N=C2)CC1OP(O)(=S)OCC1OC(N2C(NC(=O)C(C)=C2)=O)CC1OP(O)(=S)OCC1OC(N2C(NC(=O)C(C)=C2)=O)CC1OP(O)(=S)OCC1OC(N2C(NC(=O)C(C)=C2)=O)CC1OP(O)(=S)OCC1OC(N2C3=C(C(NC(N)=N3)=O)N=C2)CC1OP(O)(=S)OCC1OC(N2C(N=C(N)C=C2)=O)CC1OP(O)(=S)OCC(C(C1)OP(S)(=O)OCC2C(CC(O2)N2C(N=C(N)C=C2)=O)OP(O)(=S)OCC2C(CC(O2)N2C(NC(=O)C(C)=C2)=O)OP(O)(=S)OCC2C(CC(O2)N2C(NC(=O)C(C)=C2)=O)OP(O)(=S)OCC2C(CC(O2)N2C(N=C(N)C=C2)=O)OP(O)(=S)OCC2C(CC(O2)N2C(NC(=O)C(C)=C2)=O)OP(O)(=S)OCC2C(CC(O2)N2C(NC(=O)C(C)=C2)=O)OP(O)(=S)OCC2C(CC(O2)N2C(N=C(N)C=C2)=O)OP(O)(=S)OCC2C(CC(O2)N2C(NC(=O)C(C)=C2)=O)OP(O)(=S)OCC2C(CC(O2)N2C(NC(=O)C(C)=C2)=O)OP(O)(=S)OCC2C(CC(O2)N2C3=C(C(NC(N)=N3)=O)N=C2)OP(O)(=S)OCC2C(CC(O2)N2C(N=C(N)C=C2)=O)OP(O)(=S)OCC2C(CC(O2)N2C3=C(C(NC(N)=N3)=O)N=C2)O)OC1N1C=C(C)C(=O)NC1=O XCWFZHPEARLXJI-UHFFFAOYSA-N 0.000 description 1
• 235000013355 food flavoring agent Nutrition 0.000 description 1
• 235000003599 food sweetener Nutrition 0.000 description 1
• 229960003142 fosamprenavir Drugs 0.000 description 1
• MLBVMOWEQCZNCC-OEMFJLHTSA-N fosamprenavir Chemical compound C([C@@H]([C@H](OP(O)(O)=O)CN(CC(C)C)S(=O)(=O)C=1C=CC(N)=CC=1)NC(=O)O[C@@H]1COCC1)C1=CC=CC=C1 MLBVMOWEQCZNCC-OEMFJLHTSA-N 0.000 description 1
• 229960005102 foscarnet Drugs 0.000 description 1
• 229960000308 fosfomycin Drugs 0.000 description 1
• YMDXZJFXQJVXBF-STHAYSLISA-N fosfomycin Chemical compound C[C@@H]1O[C@@H]1P(O)(O)=O YMDXZJFXQJVXBF-STHAYSLISA-N 0.000 description 1
• 229940112424 fosfonet Drugs 0.000 description 1
• 238000005194 fractionation Methods 0.000 description 1
• 238000004108 freeze drying Methods 0.000 description 1
• 238000007710 freezing Methods 0.000 description 1
• 230000008014 freezing Effects 0.000 description 1
• 235000015203 fruit juice Nutrition 0.000 description 1
• ZEYJIQLVKGBLEM-UHFFFAOYSA-N fuberidazole Chemical compound C1=COC(C=2N=C3[CH]C=CC=C3N=2)=C1 ZEYJIQLVKGBLEM-UHFFFAOYSA-N 0.000 description 1
• 239000002316 fumigant Substances 0.000 description 1
• 239000003008 fumonisin Substances 0.000 description 1
• 201000010056 fungal meningitis Diseases 0.000 description 1
• 229960002963 ganciclovir Drugs 0.000 description 1
• IRSCQMHQWWYFCW-UHFFFAOYSA-N ganciclovir Chemical compound O=C1NC(N)=NC2=C1N=CN2COC(CO)CO IRSCQMHQWWYFCW-UHFFFAOYSA-N 0.000 description 1
• 229960003923 gatifloxacin Drugs 0.000 description 1
• 229940014259 gelatin Drugs 0.000 description 1
• 239000007903 gelatin capsule Substances 0.000 description 1
• 230000002068 genetic effect Effects 0.000 description 1
• 235000003869 genetically modified organism Nutrition 0.000 description 1
• 229960002518 gentamicin Drugs 0.000 description 1
• 210000004907 gland Anatomy 0.000 description 1
• 150000002301 glucosamine derivatives Chemical class 0.000 description 1
• 229960002867 griseofulvin Drugs 0.000 description 1
• DDUHZTYCFQRHIY-RBHXEPJQSA-N griseofulvin Chemical compound COC1=CC(=O)C[C@@H](C)[C@@]11C(=O)C(C(OC)=CC(OC)=C2Cl)=C2O1 DDUHZTYCFQRHIY-RBHXEPJQSA-N 0.000 description 1
• 239000003102 growth factor Substances 0.000 description 1
• 125000005614 guluronate group Chemical group 0.000 description 1
• 125000005613 guluronic acid group Chemical group 0.000 description 1
• 230000003394 haemopoietic effect Effects 0.000 description 1
• 229960002383 halcinonide Drugs 0.000 description 1
• 229940116364 hard fat Drugs 0.000 description 1
• 201000005787 hematologic cancer Diseases 0.000 description 1
• 230000002489 hematologic effect Effects 0.000 description 1
• CKAPSXZOOQJIBF-UHFFFAOYSA-N hexachlorobenzene Chemical compound ClC1=C(Cl)C(Cl)=C(Cl)C(Cl)=C1Cl CKAPSXZOOQJIBF-UHFFFAOYSA-N 0.000 description 1
• 229920006158 high molecular weight polymer Polymers 0.000 description 1
• 239000010903 husk Substances 0.000 description 1
• 239000000416 hydrocolloid Substances 0.000 description 1
• 229960000890 hydrocortisone Drugs 0.000 description 1
• 238000006460 hydrolysis reaction Methods 0.000 description 1
• 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
• KGVPNLBXJKTABS-UHFFFAOYSA-N hymexazol Chemical compound CC1=CC(O)=NO1 KGVPNLBXJKTABS-UHFFFAOYSA-N 0.000 description 1
• 230000000642 iatrogenic effect Effects 0.000 description 1
• 229960000374 ibacitabine Drugs 0.000 description 1
• WEVJJMPVVFNAHZ-RRKCRQDMSA-N ibacitabine Chemical compound C1=C(I)C(N)=NC(=O)N1[C@@H]1O[C@H](CO)[C@@H](O)C1 WEVJJMPVVFNAHZ-RRKCRQDMSA-N 0.000 description 1
• 229960004716 idoxuridine Drugs 0.000 description 1
• 229960002182 imipenem Drugs 0.000 description 1
• ZSKVGTPCRGIANV-ZXFLCMHBSA-N imipenem Chemical compound C1C(SCC\N=C\N)=C(C(O)=O)N2C(=O)[C@H]([C@H](O)C)[C@H]21 ZSKVGTPCRGIANV-ZXFLCMHBSA-N 0.000 description 1
• 229960002751 imiquimod Drugs 0.000 description 1
• DOUYETYNHWVLEO-UHFFFAOYSA-N imiquimod Chemical compound C1=CC=CC2=C3N(CC(C)C)C=NC3=C(N)N=C21 DOUYETYNHWVLEO-UHFFFAOYSA-N 0.000 description 1
• 230000005965 immune activity Effects 0.000 description 1
• 230000028993 immune response Effects 0.000 description 1
• 230000001506 immunosuppresive effect Effects 0.000 description 1
• 238000002513 implantation Methods 0.000 description 1
• 229960001936 indinavir Drugs 0.000 description 1
• CBVCZFGXHXORBI-PXQQMZJSSA-N indinavir Chemical compound C([C@H](N(CC1)C[C@@H](O)C[C@@H](CC=2C=CC=CC=2)C(=O)N[C@H]2C3=CC=CC=C3C[C@H]2O)C(=O)NC(C)(C)C)N1CC1=CC=CN=C1 CBVCZFGXHXORBI-PXQQMZJSSA-N 0.000 description 1
• 239000002440 industrial waste Substances 0.000 description 1
• 238000013383 initial experiment Methods 0.000 description 1
• 239000007924 injection Substances 0.000 description 1
• 238000002347 injection Methods 0.000 description 1
• 229910052500 inorganic mineral Inorganic materials 0.000 description 1
• 229960003786 inosine Drugs 0.000 description 1
• 230000000749 insecticidal effect Effects 0.000 description 1
• 108010018844 interferon type III Proteins 0.000 description 1
• 229940028894 interferon type ii Drugs 0.000 description 1
• 230000003834 intracellular effect Effects 0.000 description 1
• 238000001990 intravenous administration Methods 0.000 description 1
• 150000002497 iodine compounds Chemical class 0.000 description 1
• 239000003456 ion exchange resin Substances 0.000 description 1
• 229920003303 ion-exchange polymer Polymers 0.000 description 1
• 230000005865 ionizing radiation Effects 0.000 description 1
• 229960001888 ipratropium Drugs 0.000 description 1
• OEXHQOGQTVQTAT-JRNQLAHRSA-N ipratropium Chemical compound O([C@H]1C[C@H]2CC[C@@H](C1)[N@@+]2(C)C(C)C)C(=O)C(CO)C1=CC=CC=C1 OEXHQOGQTVQTAT-JRNQLAHRSA-N 0.000 description 1
• 229910052742 iron Inorganic materials 0.000 description 1
• JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
• 230000007794 irritation Effects 0.000 description 1
• WYXXLXHHWYNKJF-UHFFFAOYSA-N isocarvacrol Natural products CC(C)C1=CC=C(O)C(C)=C1 WYXXLXHHWYNKJF-UHFFFAOYSA-N 0.000 description 1
• 238000002955 isolation Methods 0.000 description 1
• 229960003350 isoniazid Drugs 0.000 description 1
• QRXWMOHMRWLFEY-UHFFFAOYSA-N isoniazide Chemical compound NNC(=O)C1=CC=NC=C1 QRXWMOHMRWLFEY-UHFFFAOYSA-N 0.000 description 1
• UFHLMYOGRXOCSL-UHFFFAOYSA-N isoprothiolane Chemical compound CC(C)OC(=O)C(C(=O)OC(C)C)=C1SCCS1 UFHLMYOGRXOCSL-UHFFFAOYSA-N 0.000 description 1
• 229960004130 itraconazole Drugs 0.000 description 1
• 229960000318 kanamycin Drugs 0.000 description 1
• 229930027917 kanamycin Natural products 0.000 description 1
• SBUJHOSQTJFQJX-NOAMYHISSA-N kanamycin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N SBUJHOSQTJFQJX-NOAMYHISSA-N 0.000 description 1
• 229930182823 kanamycin A Natural products 0.000 description 1
• JUTMAMXOAOYKHT-UHFFFAOYSA-N karrikinolide Natural products C1=COC=C2OC(=O)C(C)=C21 JUTMAMXOAOYKHT-UHFFFAOYSA-N 0.000 description 1
• 150000002576 ketones Chemical class 0.000 description 1
• 239000008101 lactose Substances 0.000 description 1
• 229960001627 lamivudine Drugs 0.000 description 1
• JTEGQNOMFQHVDC-NKWVEPMBSA-N lamivudine Chemical compound O=C1N=C(N)C=CN1[C@H]1O[C@@H](CO)SC1 JTEGQNOMFQHVDC-NKWVEPMBSA-N 0.000 description 1
• 229920000126 latex Polymers 0.000 description 1
• 208000032839 leukemia Diseases 0.000 description 1
• 210000000265 leukocyte Anatomy 0.000 description 1
• 229960003376 levofloxacin Drugs 0.000 description 1
• 229950008204 levosalbutamol Drugs 0.000 description 1
• 210000003041 ligament Anatomy 0.000 description 1
• 239000004571 lime Substances 0.000 description 1
• 229960003907 linezolid Drugs 0.000 description 1
• TYZROVQLWOKYKF-ZDUSSCGKSA-N linezolid Chemical compound O=C1O[C@@H](CNC(=O)C)CN1C(C=C1F)=CC=C1N1CCOCC1 TYZROVQLWOKYKF-ZDUSSCGKSA-N 0.000 description 1
• 235000019421 lipase Nutrition 0.000 description 1
• 238000010872 live dead assay kit Methods 0.000 description 1
• 244000144972 livestock Species 0.000 description 1
• 229960002422 lomefloxacin Drugs 0.000 description 1
• ZEKZLJVOYLTDKK-UHFFFAOYSA-N lomefloxacin Chemical compound FC1=C2N(CC)C=C(C(O)=O)C(=O)C2=CC(F)=C1N1CCNC(C)C1 ZEKZLJVOYLTDKK-UHFFFAOYSA-N 0.000 description 1
• 238000011866 long-term treatment Methods 0.000 description 1
• 230000007774 longterm Effects 0.000 description 1
• 229960004525 lopinavir Drugs 0.000 description 1
• 229960001977 loracarbef Drugs 0.000 description 1
• JAPHQRWPEGVNBT-UTUOFQBUSA-N loracarbef Chemical compound C1([C@H](C(=O)N[C@@H]2C(N3C(=C(Cl)CC[C@@H]32)C([O-])=O)=O)[NH3+])=CC=CC=C1 JAPHQRWPEGVNBT-UTUOFQBUSA-N 0.000 description 1
• 229950006243 loviride Drugs 0.000 description 1
• CJPLEFFCVDQQFZ-UHFFFAOYSA-N loviride Chemical compound CC(=O)C1=CC=C(C)C=C1NC(C(N)=O)C1=C(Cl)C=CC=C1Cl CJPLEFFCVDQQFZ-UHFFFAOYSA-N 0.000 description 1
• 239000003120 macrolide antibiotic agent Substances 0.000 description 1
• 229940041033 macrolides Drugs 0.000 description 1
• 229960003640 mafenide Drugs 0.000 description 1
• 235000019359 magnesium stearate Nutrition 0.000 description 1
• 229920000940 maneb Polymers 0.000 description 1
• YKSNLCVSTHTHJA-UHFFFAOYSA-L maneb Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S YKSNLCVSTHTHJA-UHFFFAOYSA-L 0.000 description 1
• 229960004710 maraviroc Drugs 0.000 description 1
• GSNHKUDZZFZSJB-QYOOZWMWSA-N maraviroc Chemical compound CC(C)C1=NN=C(C)N1[C@@H]1C[C@H](N2CC[C@H](NC(=O)C3CCC(F)(F)CC3)C=3C=CC=CC=3)CC[C@H]2C1 GSNHKUDZZFZSJB-QYOOZWMWSA-N 0.000 description 1
• 230000007246 mechanism Effects 0.000 description 1
• PSGAAPLEWMOORI-PEINSRQWSA-N medroxyprogesterone acetate Chemical compound C([C@@]12C)CC(=O)C=C1[C@@H](C)C[C@@H]1[C@@H]2CC[C@]2(C)[C@@](OC(C)=O)(C(C)=O)CC[C@H]21 PSGAAPLEWMOORI-PEINSRQWSA-N 0.000 description 1
• 229960003194 meglumine Drugs 0.000 description 1
• CIFWZNRJIBNXRE-UHFFFAOYSA-N mepanipyrim Chemical compound CC#CC1=CC(C)=NC(NC=2C=CC=CC=2)=N1 CIFWZNRJIBNXRE-UHFFFAOYSA-N 0.000 description 1
• BCTQJXQXJVLSIG-UHFFFAOYSA-N mepronil Chemical compound CC(C)OC1=CC=CC(NC(=O)C=2C(=CC=CC=2)C)=C1 BCTQJXQXJVLSIG-UHFFFAOYSA-N 0.000 description 1
• 229940101209 mercuric oxide Drugs 0.000 description 1
• QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
• 229910052753 mercury Inorganic materials 0.000 description 1
• 229960002260 meropenem Drugs 0.000 description 1
• DMJNNHOOLUXYBV-PQTSNVLCSA-N meropenem Chemical compound C=1([C@H](C)[C@@H]2[C@H](C(N2C=1C(O)=O)=O)[C@H](O)C)S[C@@H]1CN[C@H](C(=O)N(C)C)C1 DMJNNHOOLUXYBV-PQTSNVLCSA-N 0.000 description 1
• 229960004635 mesna Drugs 0.000 description 1
• 238000012269 metabolic engineering Methods 0.000 description 1
• 230000004060 metabolic process Effects 0.000 description 1
• 229910052751 metal Inorganic materials 0.000 description 1
• 239000002184 metal Substances 0.000 description 1
• 229910021645 metal ion Inorganic materials 0.000 description 1
• HYVVJDQGXFXBRZ-UHFFFAOYSA-N metam Chemical compound CNC(S)=S HYVVJDQGXFXBRZ-UHFFFAOYSA-N 0.000 description 1
• XWPZUHJBOLQNMN-UHFFFAOYSA-N metconazole Chemical compound C1=NC=NN1CC1(O)C(C)(C)CCC1CC1=CC=C(Cl)C=C1 XWPZUHJBOLQNMN-UHFFFAOYSA-N 0.000 description 1
• UZOXOBUYZGSAIW-UHFFFAOYSA-N methoxy(phenyl)carbamic acid Chemical compound CON(C(O)=O)C1=CC=CC=C1 UZOXOBUYZGSAIW-UHFFFAOYSA-N 0.000 description 1
• SPTIHHXLKJKKNM-WQLSENKSSA-N methyl (Z)-3-(fluoromethoxy)-2-[2-[(3,5,6-trichloropyridin-2-yl)oxymethyl]phenyl]prop-2-enoate Chemical compound COC(=O)C(=C/OCF)\c1ccccc1COc1nc(Cl)c(Cl)cc1Cl SPTIHHXLKJKKNM-WQLSENKSSA-N 0.000 description 1
• 229940102396 methyl bromide Drugs 0.000 description 1
• 229920000609 methyl cellulose Polymers 0.000 description 1
• 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
• TZUAKKVHNFEFBG-UHFFFAOYSA-N methyl n-[[2-(furan-2-ylmethylideneamino)phenyl]carbamothioyl]carbamate Chemical compound COC(=O)NC(=S)NC1=CC=CC=C1N=CC1=CC=CO1 TZUAKKVHNFEFBG-UHFFFAOYSA-N 0.000 description 1
• BSDQITJYKQHXQR-UHFFFAOYSA-N methyl prop-2-eneperoxoate Chemical compound COOC(=O)C=C BSDQITJYKQHXQR-UHFFFAOYSA-N 0.000 description 1
• OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical class COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 description 1
• 239000001923 methylcellulose Substances 0.000 description 1
• JVJUWCMBRUMDDQ-UHFFFAOYSA-N methylmercuric dicyanamide Chemical compound C[Hg]N=C(N)NC#N JVJUWCMBRUMDDQ-UHFFFAOYSA-N 0.000 description 1
• HIIRDDUVRXCDBN-OBGWFSINSA-N metominostrobin Chemical compound CNC(=O)C(=N\OC)\C1=CC=CC=C1OC1=CC=CC=C1 HIIRDDUVRXCDBN-OBGWFSINSA-N 0.000 description 1
• AMSPWOYQQAWRRM-UHFFFAOYSA-N metrafenone Chemical compound COC1=CC=C(Br)C(C)=C1C(=O)C1=C(C)C=C(OC)C(OC)=C1OC AMSPWOYQQAWRRM-UHFFFAOYSA-N 0.000 description 1
• 229960000282 metronidazole Drugs 0.000 description 1
• VAOCPAMSLUNLGC-UHFFFAOYSA-N metronidazole Chemical compound CC1=NC=C([N+]([O-])=O)N1CCO VAOCPAMSLUNLGC-UHFFFAOYSA-N 0.000 description 1
• 235000019813 microcrystalline cellulose Nutrition 0.000 description 1
• 239000008108 microcrystalline cellulose Substances 0.000 description 1
• 229940016286 microcrystalline cellulose Drugs 0.000 description 1
• 239000011859 microparticle Substances 0.000 description 1
• 235000019713 millet Nutrition 0.000 description 1
• 239000011707 mineral Substances 0.000 description 1
• 239000002480 mineral oil Substances 0.000 description 1
• 235000010446 mineral oil Nutrition 0.000 description 1
• 229960004023 minocycline Drugs 0.000 description 1
• 239000003595 mist Substances 0.000 description 1
• 230000004048 modification Effects 0.000 description 1
• 238000012986 modification Methods 0.000 description 1
• 229960001664 mometasone Drugs 0.000 description 1
• QLIIKPVHVRXHRI-CXSFZGCWSA-N mometasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CCl)(O)[C@@]1(C)C[C@@H]2O QLIIKPVHVRXHRI-CXSFZGCWSA-N 0.000 description 1
• 238000012544 monitoring process Methods 0.000 description 1
• 229940041009 monobactams Drugs 0.000 description 1
• 150000002772 monosaccharides Chemical class 0.000 description 1
• 229960005389 moroxydine Drugs 0.000 description 1
• 230000004660 morphological change Effects 0.000 description 1
• 229960003702 moxifloxacin Drugs 0.000 description 1
• FABPRXSRWADJSP-MEDUHNTESA-N moxifloxacin Chemical compound COC1=C(N2C[C@H]3NCCC[C@H]3C2)C(F)=CC(C(C(C(O)=O)=C2)=O)=C1N2C1CC1 FABPRXSRWADJSP-MEDUHNTESA-N 0.000 description 1
• 230000000510 mucolytic effect Effects 0.000 description 1
• 229940066491 mucolytics Drugs 0.000 description 1
• 201000007524 mucormycosis Diseases 0.000 description 1
• 210000003097 mucus Anatomy 0.000 description 1
• 210000003205 muscle Anatomy 0.000 description 1
• 230000035772 mutation Effects 0.000 description 1
• 229940031815 mycocide Drugs 0.000 description 1
• 239000002636 mycotoxin Substances 0.000 description 1
• NZMAJUHVSZBJHL-UHFFFAOYSA-N n,n-dibutylformamide Chemical compound CCCCN(C=O)CCCC NZMAJUHVSZBJHL-UHFFFAOYSA-N 0.000 description 1
• JORAUNFTUVJTNG-BSTBCYLQSA-N n-[(2s)-4-amino-1-[[(2s,3r)-1-[[(2s)-4-amino-1-oxo-1-[[(3s,6s,9s,12s,15r,18s,21s)-6,9,18-tris(2-aminoethyl)-3-[(1r)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-h Chemical compound CC(C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@H]([C@@H](C)O)CN[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCN)NC1=O.CCC(C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@H]([C@@H](C)O)CN[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCN)NC1=O JORAUNFTUVJTNG-BSTBCYLQSA-N 0.000 description 1
• OYRIKLVYHTWHCZ-UHFFFAOYSA-N n-cyclohexyl-2,5-dimethylfuran-3-carboxamide Chemical compound O1C(C)=CC(C(=O)NC2CCCCC2)=C1C OYRIKLVYHTWHCZ-UHFFFAOYSA-N 0.000 description 1
• XGXNTJHZPBRBHJ-UHFFFAOYSA-N n-phenylpyrimidin-2-amine Chemical compound N=1C=CC=NC=1NC1=CC=CC=C1 XGXNTJHZPBRBHJ-UHFFFAOYSA-N 0.000 description 1
• UQJQVUOTMVCFHX-UHFFFAOYSA-L nabam Chemical compound [Na+].[Na+].[S-]C(=S)NCCNC([S-])=S UQJQVUOTMVCFHX-UHFFFAOYSA-L 0.000 description 1
• 229960000515 nafcillin Drugs 0.000 description 1
• GPXLMGHLHQJAGZ-JTDSTZFVSA-N nafcillin Chemical compound C1=CC=CC2=C(C(=O)N[C@@H]3C(N4[C@H](C(C)(C)S[C@@H]43)C(O)=O)=O)C(OCC)=CC=C21 GPXLMGHLHQJAGZ-JTDSTZFVSA-N 0.000 description 1
• 229960004313 naftifine Drugs 0.000 description 1
• OZGNYLLQHRPOBR-DHZHZOJOSA-N naftifine Chemical compound C=1C=CC2=CC=CC=C2C=1CN(C)C\C=C\C1=CC=CC=C1 OZGNYLLQHRPOBR-DHZHZOJOSA-N 0.000 description 1
• 210000000282 nail Anatomy 0.000 description 1
• 239000007922 nasal spray Substances 0.000 description 1
• 229960004927 neomycin Drugs 0.000 description 1
• 230000001613 neoplastic effect Effects 0.000 description 1
• 229960000808 netilmicin Drugs 0.000 description 1
• ZBGPYVZLYBDXKO-HILBYHGXSA-N netilmycin Chemical compound O([C@@H]1[C@@H](N)C[C@H]([C@@H]([C@H]1O)O[C@@H]1[C@]([C@H](NC)[C@@H](O)CO1)(C)O)NCC)[C@H]1OC(CN)=CC[C@H]1N ZBGPYVZLYBDXKO-HILBYHGXSA-N 0.000 description 1
• 229960000689 nevirapine Drugs 0.000 description 1
• 229940101771 nexavir Drugs 0.000 description 1
• 229960000564 nitrofurantoin Drugs 0.000 description 1
• NXFQHRVNIOXGAQ-YCRREMRBSA-N nitrofurantoin Chemical compound O1C([N+](=O)[O-])=CC=C1\C=N\N1C(=O)NC(=O)C1 NXFQHRVNIOXGAQ-YCRREMRBSA-N 0.000 description 1
• 229910052757 nitrogen Inorganic materials 0.000 description 1
• 229960001180 norfloxacin Drugs 0.000 description 1
• OGJPXUAPXNRGGI-UHFFFAOYSA-N norfloxacin Chemical compound C1=C2N(CC)C=C(C(O)=O)C(=O)C2=CC(F)=C1N1CCNCC1 OGJPXUAPXNRGGI-UHFFFAOYSA-N 0.000 description 1
• 229920001778 nylon Polymers 0.000 description 1
• 229930183344 ochratoxin Natural products 0.000 description 1
• 229960001699 ofloxacin Drugs 0.000 description 1
• 244000039328 opportunistic pathogen Species 0.000 description 1
• 210000003463 organelle Anatomy 0.000 description 1
• 235000010292 orthophenyl phenol Nutrition 0.000 description 1
• 229960003752 oseltamivir Drugs 0.000 description 1
• VSZGPKBBMSAYNT-RRFJBIMHSA-N oseltamivir Chemical compound CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@H](NC(C)=O)[C@@H](N)C1 VSZGPKBBMSAYNT-RRFJBIMHSA-N 0.000 description 1
• MBRLOUHOWLUMFF-UHFFFAOYSA-N osthole Chemical compound C1=CC(=O)OC2=C(CC=C(C)C)C(OC)=CC=C21 MBRLOUHOWLUMFF-UHFFFAOYSA-N 0.000 description 1
• 201000009838 otomycosis Diseases 0.000 description 1
• 210000003101 oviduct Anatomy 0.000 description 1
• 229960001019 oxacillin Drugs 0.000 description 1
• UWYHMGVUTGAWSP-JKIFEVAISA-N oxacillin Chemical compound N([C@@H]1C(N2[C@H](C(C)(C)S[C@@H]21)C(O)=O)=O)C(=O)C1=C(C)ON=C1C1=CC=CC=C1 UWYHMGVUTGAWSP-JKIFEVAISA-N 0.000 description 1
• 229960000797 oxitropium Drugs 0.000 description 1
• NVOYVOBDTVTBDX-PMEUIYRNSA-N oxitropium Chemical compound CC[N+]1(C)[C@H]2C[C@@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)C1=CC=CC=C1 NVOYVOBDTVTBDX-PMEUIYRNSA-N 0.000 description 1
• 239000001301 oxygen Substances 0.000 description 1
• 229910052760 oxygen Inorganic materials 0.000 description 1
• 238000006213 oxygenation reaction Methods 0.000 description 1
• 229960000625 oxytetracycline Drugs 0.000 description 1
• IWVCMVBTMGNXQD-PXOLEDIWSA-N oxytetracycline Chemical compound C1=CC=C2[C@](O)(C)[C@H]3[C@H](O)[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-PXOLEDIWSA-N 0.000 description 1
• 235000019366 oxytetracycline Nutrition 0.000 description 1
• LSQZJLSUYDQPKJ-UHFFFAOYSA-N p-Hydroxyampicillin Natural products O=C1N2C(C(O)=O)C(C)(C)SC2C1NC(=O)C(N)C1=CC=C(O)C=C1 LSQZJLSUYDQPKJ-UHFFFAOYSA-N 0.000 description 1
• 238000004806 packaging method and process Methods 0.000 description 1
• 238000010422 painting Methods 0.000 description 1
• 238000009116 palliative therapy Methods 0.000 description 1
• 229950011346 panipenem Drugs 0.000 description 1
• 210000003695 paranasal sinus Anatomy 0.000 description 1
• 239000008010 parenteral excipient Substances 0.000 description 1
• 239000013618 particulate matter Substances 0.000 description 1
• 235000020232 peanut Nutrition 0.000 description 1
• 229960001179 penciclovir Drugs 0.000 description 1
• OGYFATSSENRIKG-UHFFFAOYSA-N pencycuron Chemical compound C1=CC(Cl)=CC=C1CN(C(=O)NC=1C=CC=CC=1)C1CCCC1 OGYFATSSENRIKG-UHFFFAOYSA-N 0.000 description 1
• 229940056360 penicillin g Drugs 0.000 description 1
• 229940056367 penicillin v Drugs 0.000 description 1
• 150000002960 penicillins Chemical class 0.000 description 1
• LKPLKUMXSAEKID-UHFFFAOYSA-N pentachloronitrobenzene Chemical compound [O-][N+](=O)C1=C(Cl)C(Cl)=C(Cl)C(Cl)=C1Cl LKPLKUMXSAEKID-UHFFFAOYSA-N 0.000 description 1
• IZUPBVBPLAPZRR-UHFFFAOYSA-M pentachlorophenolate Chemical compound [O-]C1=C(Cl)C(Cl)=C(Cl)C(Cl)=C1Cl IZUPBVBPLAPZRR-UHFFFAOYSA-M 0.000 description 1
• 229940111202 pepsin Drugs 0.000 description 1
• 229960001084 peramivir Drugs 0.000 description 1
• XRQDFNLINLXZLB-CKIKVBCHSA-N peramivir Chemical compound CCC(CC)[C@H](NC(C)=O)[C@@H]1[C@H](O)[C@@H](C(O)=O)C[C@H]1NC(N)=N XRQDFNLINLXZLB-CKIKVBCHSA-N 0.000 description 1
• 230000010412 perfusion Effects 0.000 description 1
• 239000000825 pharmaceutical preparation Substances 0.000 description 1
• 229940127557 pharmaceutical product Drugs 0.000 description 1
• 150000002989 phenols Chemical class 0.000 description 1
• BPLBGHOLXOTWMN-MBNYWOFBSA-N phenoxymethylpenicillin Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)COC1=CC=CC=C1 BPLBGHOLXOTWMN-MBNYWOFBSA-N 0.000 description 1
• 229940096826 phenylmercuric acetate Drugs 0.000 description 1
• GPFAJKDEDBRFOS-FKQDBXSBSA-N pholcodine Chemical compound O([C@@H]1[C@]23CCN([C@H](C4)[C@@H]3C=C[C@@H]1O)C)C1=C2C4=CC=C1OCCN1CCOCC1 GPFAJKDEDBRFOS-FKQDBXSBSA-N 0.000 description 1
• 229960002808 pholcodine Drugs 0.000 description 1
• XUYJLQHKOGNDPB-UHFFFAOYSA-N phosphonoacetic acid Chemical compound OC(=O)CP(O)(O)=O XUYJLQHKOGNDPB-UHFFFAOYSA-N 0.000 description 1
• XKJCHHZQLQNZHY-UHFFFAOYSA-N phthalimide Chemical compound C1=CC=C2C(=O)NC(=O)C2=C1 XKJCHHZQLQNZHY-UHFFFAOYSA-N 0.000 description 1
• IBSNKSODLGJUMQ-SDNWHVSQSA-N picoxystrobin Chemical compound CO\C=C(\C(=O)OC)C1=CC=CC=C1COC1=CC=CC(C(F)(F)F)=N1 IBSNKSODLGJUMQ-SDNWHVSQSA-N 0.000 description 1
• 229960002292 piperacillin Drugs 0.000 description 1
• WCMIIGXFCMNQDS-IDYPWDAWSA-M piperacillin sodium Chemical compound [Na+].O=C1C(=O)N(CC)CCN1C(=O)N[C@H](C=1C=CC=CC=1)C(=O)N[C@@H]1C(=O)N2[C@@H](C([O-])=O)C(C)(C)S[C@@H]21 WCMIIGXFCMNQDS-IDYPWDAWSA-M 0.000 description 1
• 229960005414 pirbuterol Drugs 0.000 description 1
• 229960001237 podophyllotoxin Drugs 0.000 description 1
• YJGVMLPVUAXIQN-XVVDYKMHSA-N podophyllotoxin Chemical compound COC1=C(OC)C(OC)=CC([C@@H]2C3=CC=4OCOC=4C=C3[C@H](O)[C@@H]3[C@@H]2C(OC3)=O)=C1 YJGVMLPVUAXIQN-XVVDYKMHSA-N 0.000 description 1
• YVCVYCSAAZQOJI-UHFFFAOYSA-N podophyllotoxin Natural products COC1=C(O)C(OC)=CC(C2C3=CC=4OCOC=4C=C3C(O)C3C2C(OC3)=O)=C1 YVCVYCSAAZQOJI-UHFFFAOYSA-N 0.000 description 1
• 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
• 229920002492 poly(sulfone) Polymers 0.000 description 1
• 229920002647 polyamide Polymers 0.000 description 1
• 239000004417 polycarbonate Substances 0.000 description 1
• 229920000515 polycarbonate Polymers 0.000 description 1
• 229920000728 polyester Polymers 0.000 description 1
• 229920002530 polyetherether ketone Polymers 0.000 description 1
• 229920001223 polyethylene glycol Polymers 0.000 description 1
• 229920000139 polyethylene terephthalate Polymers 0.000 description 1
• 239000005020 polyethylene terephthalate Substances 0.000 description 1
• 229920000193 polymethacrylate Polymers 0.000 description 1
• 239000004926 polymethyl methacrylate Substances 0.000 description 1
• 229920000024 polymyxin B Polymers 0.000 description 1
• XDJYMJULXQKGMM-UHFFFAOYSA-N polymyxin E1 Natural products CCC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(C(C)O)NC(=O)C(CCN)NC(=O)C(CCN)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCN)NC1=O XDJYMJULXQKGMM-UHFFFAOYSA-N 0.000 description 1
• KNIWPHSUTGNZST-UHFFFAOYSA-N polymyxin E2 Natural products CC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(C(C)O)NC(=O)C(CCN)NC(=O)C(CCN)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCN)NC1=O KNIWPHSUTGNZST-UHFFFAOYSA-N 0.000 description 1
• 229960005266 polymyxin b Drugs 0.000 description 1
• 229920000098 polyolefin Polymers 0.000 description 1
• 239000003910 polypeptide antibiotic agent Substances 0.000 description 1
• 229920001155 polypropylene Polymers 0.000 description 1
• 229920001296 polysiloxane Polymers 0.000 description 1
• 229920002223 polystyrene Polymers 0.000 description 1
• 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
• 229920002981 polyvinylidene fluoride Polymers 0.000 description 1
• 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
• 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
• 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
• 235000003784 poor nutrition Nutrition 0.000 description 1
• 235000015277 pork Nutrition 0.000 description 1
• 239000011591 potassium Substances 0.000 description 1
• 229910052700 potassium Inorganic materials 0.000 description 1
• TZLVRPLSVNESQC-UHFFFAOYSA-N potassium azide Chemical compound [K+].[N-]=[N+]=[N-] TZLVRPLSVNESQC-UHFFFAOYSA-N 0.000 description 1
• 229940016373 potassium polysulfide Drugs 0.000 description 1
• ZNNZYHKDIALBAK-UHFFFAOYSA-M potassium thiocyanate Chemical compound [K+].[S-]C#N ZNNZYHKDIALBAK-UHFFFAOYSA-M 0.000 description 1
• 229940116357 potassium thiocyanate Drugs 0.000 description 1
• 244000144977 poultry Species 0.000 description 1
• 235000013594 poultry meat Nutrition 0.000 description 1
• 229960001621 povidone-iodine Drugs 0.000 description 1
• 229960002794 prednicarbate Drugs 0.000 description 1
• FNPXMHRZILFCKX-KAJVQRHHSA-N prednicarbate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)COC(=O)CC)(OC(=O)OCC)[C@@]1(C)C[C@@H]2O FNPXMHRZILFCKX-KAJVQRHHSA-N 0.000 description 1
• 229960004618 prednisone Drugs 0.000 description 1
• XOFYZVNMUHMLCC-ZPOLXVRWSA-N prednisone Chemical compound O=C1C=C[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 XOFYZVNMUHMLCC-ZPOLXVRWSA-N 0.000 description 1
• 230000002335 preservative effect Effects 0.000 description 1
• 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
• TVLSRXXIMLFWEO-UHFFFAOYSA-N prochloraz Chemical compound C1=CN=CN1C(=O)N(CCC)CCOC1=C(Cl)C=C(Cl)C=C1Cl TVLSRXXIMLFWEO-UHFFFAOYSA-N 0.000 description 1
• QXJKBPAVAHBARF-BETUJISGSA-N procymidone Chemical compound O=C([C@]1(C)C[C@@]1(C1=O)C)N1C1=CC(Cl)=CC(Cl)=C1 QXJKBPAVAHBARF-BETUJISGSA-N 0.000 description 1
• WTFXJFJYEJZMFO-UHFFFAOYSA-N propamidine Chemical compound C1=CC(C(=N)N)=CC=C1OCCCOC1=CC=C(C(N)=N)C=C1 WTFXJFJYEJZMFO-UHFFFAOYSA-N 0.000 description 1
• 229960003761 propamidine Drugs 0.000 description 1
• WZZLDXDUQPOXNW-UHFFFAOYSA-N propamocarb Chemical compound CCCOC(=O)NCCCN(C)C WZZLDXDUQPOXNW-UHFFFAOYSA-N 0.000 description 1
• 239000003380 propellant Substances 0.000 description 1
• STJLVHWMYQXCPB-UHFFFAOYSA-N propiconazole Chemical compound O1C(CCC)COC1(C=1C(=CC(Cl)=CC=1)Cl)CN1N=CN=C1 STJLVHWMYQXCPB-UHFFFAOYSA-N 0.000 description 1
• XJMOSONTPMZWPB-UHFFFAOYSA-M propidium iodide Chemical compound [I-].[I-].C12=CC(N)=CC=C2C2=CC=C(N)C=C2[N+](CCC[N+](C)(CC)CC)=C1C1=CC=CC=C1 XJMOSONTPMZWPB-UHFFFAOYSA-M 0.000 description 1
• LZFIOSVZIQOVFW-UHFFFAOYSA-N propyl 2-hydroxybenzoate Chemical class CCCOC(=O)C1=CC=CC=C1O LZFIOSVZIQOVFW-UHFFFAOYSA-N 0.000 description 1
• FLVBXVXXXMLMOX-UHFFFAOYSA-N proquinazid Chemical compound C1=C(I)C=C2C(=O)N(CCC)C(OCCC)=NC2=C1 FLVBXVXXXMLMOX-UHFFFAOYSA-N 0.000 description 1
• 230000017854 proteolysis Effects 0.000 description 1
• 239000008262 pumice Substances 0.000 description 1
• 229960005206 pyrazinamide Drugs 0.000 description 1
• IPEHBUMCGVEMRF-UHFFFAOYSA-N pyrazinecarboxamide Chemical compound NC(=O)C1=CN=CC=N1 IPEHBUMCGVEMRF-UHFFFAOYSA-N 0.000 description 1
• UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
• ZLIBICFPKPWGIZ-UHFFFAOYSA-N pyrimethanil Chemical compound CC1=CC(C)=NC(NC=2C=CC=CC=2)=N1 ZLIBICFPKPWGIZ-UHFFFAOYSA-N 0.000 description 1
• XRJLAOUDSILTFT-UHFFFAOYSA-N pyroquilon Chemical compound O=C1CCC2=CC=CC3=C2N1CC3 XRJLAOUDSILTFT-UHFFFAOYSA-N 0.000 description 1
• MIXMJCQRHVAJIO-TZHJZOAOSA-N qk4dys664x Chemical compound O.C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@@H]1[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O.C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@@H]1[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O MIXMJCQRHVAJIO-TZHJZOAOSA-N 0.000 description 1
• 125000001453 quaternary ammonium group Chemical group 0.000 description 1
• 150000007660 quinolones Chemical class 0.000 description 1
• FBQQHUGEACOBDN-UHFFFAOYSA-N quinomethionate Chemical compound N1=C2SC(=O)SC2=NC2=CC(C)=CC=C21 FBQQHUGEACOBDN-UHFFFAOYSA-N 0.000 description 1
• WRPIRSINYZBGPK-UHFFFAOYSA-N quinoxyfen Chemical compound C1=CC(F)=CC=C1OC1=CC=NC2=CC(Cl)=CC(Cl)=C12 WRPIRSINYZBGPK-UHFFFAOYSA-N 0.000 description 1
• 229940052337 quinupristin/dalfopristin Drugs 0.000 description 1
• 229960004742 raltegravir Drugs 0.000 description 1
• CZFFBEXEKNGXKS-UHFFFAOYSA-N raltegravir Chemical compound O1C(C)=NN=C1C(=O)NC(C)(C)C1=NC(C(=O)NCC=2C=CC(F)=CC=2)=C(O)C(=O)N1C CZFFBEXEKNGXKS-UHFFFAOYSA-N 0.000 description 1
• 238000002708 random mutagenesis Methods 0.000 description 1
• XFGOMLIRJYURLQ-GOKYHWASSA-N razupenem Chemical compound C=1([C@H](C)[C@@H]2[C@H](C(N2C=1C(O)=O)=O)[C@H](O)C)SC(SC=1)=NC=1C1=C[C@H](C)NC1 XFGOMLIRJYURLQ-GOKYHWASSA-N 0.000 description 1
• 238000011084 recovery Methods 0.000 description 1
• 230000008439 repair process Effects 0.000 description 1
• 230000003252 repetitive effect Effects 0.000 description 1
• 230000003362 replicative effect Effects 0.000 description 1
• 230000008261 resistance mechanism Effects 0.000 description 1
• 230000000241 respiratory effect Effects 0.000 description 1
• 229960000329 ribavirin Drugs 0.000 description 1
• HZCAHMRRMINHDJ-DBRKOABJSA-N ribavirin Natural products O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1N=CN=C1 HZCAHMRRMINHDJ-DBRKOABJSA-N 0.000 description 1
• JQXXHWHPUNPDRT-WLSIYKJHSA-N rifampicin Chemical compound O([C@](C1=O)(C)O/C=C/[C@@H]([C@H]([C@@H](OC(C)=O)[C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)\C=C\C=C(C)/C(=O)NC=2C(O)=C3C([O-])=C4C)C)OC)C4=C1C3=C(O)C=2\C=N\N1CC[NH+](C)CC1 JQXXHWHPUNPDRT-WLSIYKJHSA-N 0.000 description 1
• 229960001225 rifampicin Drugs 0.000 description 1
• 229960000888 rimantadine Drugs 0.000 description 1
• 229960000311 ritonavir Drugs 0.000 description 1
• NCDNCNXCDXHOMX-XGKFQTDJSA-N ritonavir Chemical compound N([C@@H](C(C)C)C(=O)N[C@H](C[C@H](O)[C@H](CC=1C=CC=CC=1)NC(=O)OCC=1SC=NC=1)CC=1C=CC=CC=1)C(=O)N(C)CC1=CSC(C(C)C)=N1 NCDNCNXCDXHOMX-XGKFQTDJSA-N 0.000 description 1
• 238000009666 routine test Methods 0.000 description 1
• 235000002020 sage Nutrition 0.000 description 1
• WKEDVNSFRWHDNR-UHFFFAOYSA-N salicylanilide Chemical compound OC1=CC=CC=C1C(=O)NC1=CC=CC=C1 WKEDVNSFRWHDNR-UHFFFAOYSA-N 0.000 description 1
• 229950000975 salicylanilide Drugs 0.000 description 1
• 210000003296 saliva Anatomy 0.000 description 1
• 229960004017 salmeterol Drugs 0.000 description 1
• 235000019515 salmon Nutrition 0.000 description 1
• 229940074353 santonin Drugs 0.000 description 1
• 229960001852 saquinavir Drugs 0.000 description 1
• QWAXKHKRTORLEM-UGJKXSETSA-N saquinavir Chemical compound C([C@@H]([C@H](O)CN1C[C@H]2CCCC[C@H]2C[C@H]1C(=O)NC(C)(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)C=1N=C2C=CC=CC2=CC=1)C1=CC=CC=C1 QWAXKHKRTORLEM-UGJKXSETSA-N 0.000 description 1
• 238000009738 saturating Methods 0.000 description 1
• 235000015067 sauces Nutrition 0.000 description 1
• 208000005687 scabies Diseases 0.000 description 1
• 229940100890 silver compound Drugs 0.000 description 1
• 150000003379 silver compounds Chemical class 0.000 description 1
• 238000002741 site-directed mutagenesis Methods 0.000 description 1
• 238000005549 size reduction Methods 0.000 description 1
• 231100000019 skin ulcer Toxicity 0.000 description 1
• 229910052708 sodium Inorganic materials 0.000 description 1
• 239000008354 sodium chloride injection Substances 0.000 description 1
• UKLNMMHNWFDKNT-UHFFFAOYSA-M sodium chlorite Chemical compound [Na+].[O-]Cl=O UKLNMMHNWFDKNT-UHFFFAOYSA-M 0.000 description 1
• 229960002218 sodium chlorite Drugs 0.000 description 1
• SUKJFIGYRHOWBL-UHFFFAOYSA-N sodium hypochlorite Chemical compound [Na+].Cl[O-] SUKJFIGYRHOWBL-UHFFFAOYSA-N 0.000 description 1
• 229910001415 sodium ion Inorganic materials 0.000 description 1
• HYHCSLBZRBJJCH-UHFFFAOYSA-N sodium polysulfide Chemical compound [Na+].S HYHCSLBZRBJJCH-UHFFFAOYSA-N 0.000 description 1
• IJRHDFLHUATAOS-DPMBMXLASA-M sodium ricinoleate Chemical compound [Na+].CCCCCC[C@@H](O)C\C=C/CCCCCCCC([O-])=O IJRHDFLHUATAOS-DPMBMXLASA-M 0.000 description 1
• HCJLVWUMMKIQIM-UHFFFAOYSA-M sodium;2,3,4,5,6-pentachlorophenolate Chemical compound [Na+].[O-]C1=C(Cl)C(Cl)=C(Cl)C(Cl)=C1Cl HCJLVWUMMKIQIM-UHFFFAOYSA-M 0.000 description 1
• WSFQLUVWDKCYSW-UHFFFAOYSA-M sodium;2-hydroxy-3-morpholin-4-ylpropane-1-sulfonate Chemical compound [Na+].[O-]S(=O)(=O)CC(O)CN1CCOCC1 WSFQLUVWDKCYSW-UHFFFAOYSA-M 0.000 description 1
• BUFQZEHPOKLSTP-UHFFFAOYSA-M sodium;oxido hydrogen sulfate Chemical compound [Na+].OS(=O)(=O)O[O-] BUFQZEHPOKLSTP-UHFFFAOYSA-M 0.000 description 1
• 239000008247 solid mixture Substances 0.000 description 1
• 239000007790 solid phase Substances 0.000 description 1
• 238000005063 solubilization Methods 0.000 description 1
• 230000007928 solubilization Effects 0.000 description 1
• 239000000600 sorbitol Substances 0.000 description 1
• 235000010356 sorbitol Nutrition 0.000 description 1
• 235000014347 soups Nutrition 0.000 description 1
• 229960000268 spectinomycin Drugs 0.000 description 1
• UNFWWIHTNXNPBV-WXKVUWSESA-N spectinomycin Chemical compound O([C@@H]1[C@@H](NC)[C@@H](O)[C@H]([C@@H]([C@H]1O1)O)NC)[C@]2(O)[C@H]1O[C@H](C)CC2=O UNFWWIHTNXNPBV-WXKVUWSESA-N 0.000 description 1
• 238000001228 spectrum Methods 0.000 description 1
• PUYXTUJWRLOUCW-UHFFFAOYSA-N spiroxamine Chemical compound O1C(CN(CC)CCC)COC11CCC(C(C)(C)C)CC1 PUYXTUJWRLOUCW-UHFFFAOYSA-N 0.000 description 1
• 238000001694 spray drying Methods 0.000 description 1
• 239000003381 stabilizer Substances 0.000 description 1
• 238000010186 staining Methods 0.000 description 1
• 239000010935 stainless steel Substances 0.000 description 1
• 229910001220 stainless steel Inorganic materials 0.000 description 1
• 238000012289 standard assay Methods 0.000 description 1
• 235000019698 starch Nutrition 0.000 description 1
• 229960001203 stavudine Drugs 0.000 description 1
• 239000010959 steel Substances 0.000 description 1
• JNYSEDHQJCOWQU-UHFFFAOYSA-N stepronin Chemical compound OC(=O)CNC(=O)C(C)SC(=O)C1=CC=CS1 JNYSEDHQJCOWQU-UHFFFAOYSA-N 0.000 description 1
• 238000011146 sterile filtration Methods 0.000 description 1
• 239000008174 sterile solution Substances 0.000 description 1
• 239000008227 sterile water for injection Substances 0.000 description 1
• 230000001954 sterilising effect Effects 0.000 description 1
• 238000004659 sterilization and disinfection Methods 0.000 description 1
• 150000003432 sterols Chemical class 0.000 description 1
• 235000003702 sterols Nutrition 0.000 description 1
• 239000000021 stimulant Substances 0.000 description 1
• 229960005322 streptomycin Drugs 0.000 description 1
• 201000009867 subcutaneous mycosis Diseases 0.000 description 1
• 239000005720 sucrose Substances 0.000 description 1
• 229960002673 sulfacetamide Drugs 0.000 description 1
• SKIVFJLNDNKQPD-UHFFFAOYSA-N sulfacetamide Chemical compound CC(=O)NS(=O)(=O)C1=CC=C(N)C=C1 SKIVFJLNDNKQPD-UHFFFAOYSA-N 0.000 description 1
• 229960000654 sulfafurazole Drugs 0.000 description 1
• 229960005158 sulfamethizole Drugs 0.000 description 1
• VACCAVUAMIDAGB-UHFFFAOYSA-N sulfamethizole Chemical compound S1C(C)=NN=C1NS(=O)(=O)C1=CC=C(N)C=C1 VACCAVUAMIDAGB-UHFFFAOYSA-N 0.000 description 1
• NCEXYHBECQHGNR-QZQOTICOSA-N sulfasalazine Chemical compound C1=C(O)C(C(=O)O)=CC(\N=N\C=2C=CC(=CC=2)S(=O)(=O)NC=2N=CC=CC=2)=C1 NCEXYHBECQHGNR-QZQOTICOSA-N 0.000 description 1
• 229960001940 sulfasalazine Drugs 0.000 description 1
• NCEXYHBECQHGNR-UHFFFAOYSA-N sulfasalazine Natural products C1=C(O)C(C(=O)O)=CC(N=NC=2C=CC(=CC=2)S(=O)(=O)NC=2N=CC=CC=2)=C1 NCEXYHBECQHGNR-UHFFFAOYSA-N 0.000 description 1
• 239000011593 sulfur Substances 0.000 description 1
• 201000009862 superficial mycosis Diseases 0.000 description 1
• 238000001356 surgical procedure Methods 0.000 description 1
• 230000004083 survival effect Effects 0.000 description 1
• 239000000375 suspending agent Substances 0.000 description 1
• 230000002459 sustained effect Effects 0.000 description 1
• 239000003765 sweetening agent Substances 0.000 description 1
• 229920002994 synthetic fiber Polymers 0.000 description 1
• 208000029241 systemic basidiobolomycosis Diseases 0.000 description 1
• 239000000454 talc Substances 0.000 description 1
• 229910052623 talc Inorganic materials 0.000 description 1
• 235000012222 talc Nutrition 0.000 description 1
• 235000013616 tea Nutrition 0.000 description 1
• ROZUQUDEWZIBHV-UHFFFAOYSA-N tecloftalam Chemical compound OC(=O)C1=C(Cl)C(Cl)=C(Cl)C(Cl)=C1C(=O)NC1=CC=CC(Cl)=C1Cl ROZUQUDEWZIBHV-UHFFFAOYSA-N 0.000 description 1
• 210000002435 tendon Anatomy 0.000 description 1
• 229960004556 tenofovir Drugs 0.000 description 1
• SGOIRFVFHAKUTI-ZCFIWIBFSA-N tenofovir (anhydrous) Chemical compound N1=CN=C2N(C[C@@H](C)OCP(O)(O)=O)C=NC2=C1N SGOIRFVFHAKUTI-ZCFIWIBFSA-N 0.000 description 1
• 229960001355 tenofovir disoproxil Drugs 0.000 description 1
• JFVZFKDSXNQEJW-CQSZACIVSA-N tenofovir disoproxil Chemical compound N1=CN=C2N(C[C@@H](C)OCP(=O)(OCOC(=O)OC(C)C)OCOC(=O)OC(C)C)C=NC2=C1N JFVZFKDSXNQEJW-CQSZACIVSA-N 0.000 description 1
• VCMJCVGFSROFHV-WZGZYPNHSA-N tenofovir disoproxil fumarate Chemical compound OC(=O)\C=C\C(O)=O.N1=CN=C2N(C[C@@H](C)OCP(=O)(OCOC(=O)OC(C)C)OCOC(=O)OC(C)C)C=NC2=C1N VCMJCVGFSROFHV-WZGZYPNHSA-N 0.000 description 1
• BWMISRWJRUSYEX-SZKNIZGXSA-N terbinafine hydrochloride Chemical compound Cl.C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 BWMISRWJRUSYEX-SZKNIZGXSA-N 0.000 description 1
• IWVCMVBTMGNXQD-UHFFFAOYSA-N terramycin dehydrate Natural products C1=CC=C2C(O)(C)C3C(O)C4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-UHFFFAOYSA-N 0.000 description 1
• UGNWTBMOAKPKBL-UHFFFAOYSA-N tetrachloro-1,4-benzoquinone Chemical compound ClC1=C(Cl)C(=O)C(Cl)=C(Cl)C1=O UGNWTBMOAKPKBL-UHFFFAOYSA-N 0.000 description 1
• 229960002180 tetracycline Drugs 0.000 description 1
• 229930101283 tetracycline Natural products 0.000 description 1
• 229940040944 tetracyclines Drugs 0.000 description 1
• AUZONCFQVSMFAP-UHFFFAOYSA-N tetraethylthiuram disulfide Natural products CCN(CC)C(=S)SSC(=S)N(CC)CC AUZONCFQVSMFAP-UHFFFAOYSA-N 0.000 description 1
• 229960000278 theophylline Drugs 0.000 description 1
• VLLMWSRANPNYQX-UHFFFAOYSA-N thiadiazole Chemical compound C1=CSN=N1.C1=CSN=N1 VLLMWSRANPNYQX-UHFFFAOYSA-N 0.000 description 1
• WOSNCVAPUOFXEH-UHFFFAOYSA-N thifluzamide Chemical compound S1C(C)=NC(C(F)(F)F)=C1C(=O)NC1=C(Br)C=C(OC(F)(F)F)C=C1Br WOSNCVAPUOFXEH-UHFFFAOYSA-N 0.000 description 1
• 150000003573 thiols Chemical class 0.000 description 1
• 229930192474 thiophene Natural products 0.000 description 1
• ILERPRJWJPJZDN-UHFFFAOYSA-N thioquinox Chemical compound C1=CC=C2N=C(SC(=S)S3)C3=NC2=C1 ILERPRJWJPJZDN-UHFFFAOYSA-N 0.000 description 1
• 229960004659 ticarcillin Drugs 0.000 description 1
• OHKOGUYZJXTSFX-KZFFXBSXSA-N ticarcillin Chemical compound C=1([C@@H](C(O)=O)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)C=CSC=1 OHKOGUYZJXTSFX-KZFFXBSXSA-N 0.000 description 1
• 229960004214 tioconazole Drugs 0.000 description 1
• 229960004402 tiopronin Drugs 0.000 description 1
• LERNTVKEWCAPOY-DZZGSBJMSA-N tiotropium Chemical compound O([C@H]1C[C@@H]2[N+]([C@H](C1)[C@@H]1[C@H]2O1)(C)C)C(=O)C(O)(C=1SC=CC=1)C1=CC=CS1 LERNTVKEWCAPOY-DZZGSBJMSA-N 0.000 description 1
• 229940110309 tiotropium Drugs 0.000 description 1
• 229960000838 tipranavir Drugs 0.000 description 1
• NZPXPXAGXYTROM-FYBSXPHGSA-N tipranavir Chemical compound C([C@@]1(CCC)OC(O)=C([C@H](CC)C=2C=C(NS(=O)(=O)C=3N=CC(=CC=3)C(F)(F)F)C=CC=2)C(=O)C1)CC1=CC=CC=C1 NZPXPXAGXYTROM-FYBSXPHGSA-N 0.000 description 1
• 239000010936 titanium Substances 0.000 description 1
• 229910052719 titanium Inorganic materials 0.000 description 1
• 229960000707 tobramycin Drugs 0.000 description 1
• NLVFBUXFDBBNBW-PBSUHMDJSA-N tobramycin Chemical compound N[C@@H]1C[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N NLVFBUXFDBBNBW-PBSUHMDJSA-N 0.000 description 1
• OBZIQQJJIKNWNO-UHFFFAOYSA-N tolclofos-methyl Chemical group COP(=S)(OC)OC1=C(Cl)C=C(C)C=C1Cl OBZIQQJJIKNWNO-UHFFFAOYSA-N 0.000 description 1
• HYVWIQDYBVKITD-UHFFFAOYSA-N tolylfluanid Chemical compound CN(C)S(=O)(=O)N(SC(F)(Cl)Cl)C1=CC=C(C)C=C1 HYVWIQDYBVKITD-UHFFFAOYSA-N 0.000 description 1
• 238000011200 topical administration Methods 0.000 description 1
• 231100000331 toxic Toxicity 0.000 description 1
• 230000002588 toxic effect Effects 0.000 description 1
• 239000000196 tragacanth Substances 0.000 description 1
• 235000010487 tragacanth Nutrition 0.000 description 1
• 229940116362 tragacanth Drugs 0.000 description 1
• 238000013518 transcription Methods 0.000 description 1
• 230000035897 transcription Effects 0.000 description 1
• 238000012546 transfer Methods 0.000 description 1
• BAZVSMNPJJMILC-UHFFFAOYSA-N triadimenol Chemical compound C1=NC=NN1C(C(O)C(C)(C)C)OC1=CC=C(Cl)C=C1 BAZVSMNPJJMILC-UHFFFAOYSA-N 0.000 description 1
• 229960005294 triamcinolone Drugs 0.000 description 1
• GFNANZIMVAIWHM-OBYCQNJPSA-N triamcinolone Chemical compound O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@]([C@H](O)C4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 GFNANZIMVAIWHM-OBYCQNJPSA-N 0.000 description 1
• YWBFPKPWMSWWEA-UHFFFAOYSA-O triazolopyrimidine Chemical compound BrC1=CC=CC(C=2N=C3N=CN[N+]3=C(NCC=3C=CN=CC=3)C=2)=C1 YWBFPKPWMSWWEA-UHFFFAOYSA-O 0.000 description 1
• IQGKIPDJXCAMSM-UHFFFAOYSA-N triazoxide Chemical compound N=1C2=CC=C(Cl)C=C2[N+]([O-])=NC=1N1C=CN=C1 IQGKIPDJXCAMSM-UHFFFAOYSA-N 0.000 description 1
• QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
• 229940055035 trichophyton verrucosum Drugs 0.000 description 1
• LZAJKCZTKKKZNT-PMNGPLLRSA-N trichothecene Chemical compound C12([C@@]3(CC[C@H]2OC2C=C(CCC23C)C)C)CO1 LZAJKCZTKKKZNT-PMNGPLLRSA-N 0.000 description 1
• 150000003327 trichothecene derivatives Chemical class 0.000 description 1
• 229960003500 triclosan Drugs 0.000 description 1
• DQJCHOQLCLEDLL-UHFFFAOYSA-N tricyclazole Chemical compound CC1=CC=CC2=C1N1C=NN=C1S2 DQJCHOQLCLEDLL-UHFFFAOYSA-N 0.000 description 1
• ONCZDRURRATYFI-TVJDWZFNSA-N trifloxystrobin Chemical compound CO\N=C(\C(=O)OC)C1=CC=CC=C1CO\N=C(/C)C1=CC=CC(C(F)(F)F)=C1 ONCZDRURRATYFI-TVJDWZFNSA-N 0.000 description 1
• HSMVPDGQOIQYSR-KGENOOAVSA-N triflumizole Chemical compound C1=CN=CN1C(/COCCC)=N/C1=CC=C(Cl)C=C1C(F)(F)F HSMVPDGQOIQYSR-KGENOOAVSA-N 0.000 description 1
• AXVOAMVQOCBPQT-UHFFFAOYSA-N triphos Chemical compound C=1C=CC=CC=1P(C=1C=CC=CC=1)CCP(C=1C=CC=CC=1)CCP(C=1C=CC=CC=1)C1=CC=CC=C1 AXVOAMVQOCBPQT-UHFFFAOYSA-N 0.000 description 1
• 229960005041 troleandomycin Drugs 0.000 description 1
• LQCLVBQBTUVCEQ-QTFUVMRISA-N troleandomycin Chemical compound O1[C@@H](C)[C@H](OC(C)=O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](C)C(=O)O[C@H](C)[C@H](C)[C@H](OC(C)=O)[C@@H](C)C(=O)[C@@]2(OC2)C[C@H](C)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)OC(C)=O)[C@H]1C LQCLVBQBTUVCEQ-QTFUVMRISA-N 0.000 description 1
• 229960000497 trovafloxacin Drugs 0.000 description 1
• WVPSKSLAZQPAKQ-CDMJZVDBSA-N trovafloxacin Chemical compound C([C@H]1[C@@H]([C@H]1C1)N)N1C(C(=CC=1C(=O)C(C(O)=O)=C2)F)=NC=1N2C1=CC=C(F)C=C1F WVPSKSLAZQPAKQ-CDMJZVDBSA-N 0.000 description 1
• 239000012588 trypsin Substances 0.000 description 1
• 229960001322 trypsin Drugs 0.000 description 1
• 238000002604 ultrasonography Methods 0.000 description 1
• 229960004626 umifenovir Drugs 0.000 description 1
• KCFYEAOKVJSACF-UHFFFAOYSA-N umifenovir Chemical compound CN1C2=CC(Br)=C(O)C(CN(C)C)=C2C(C(=O)OCC)=C1CSC1=CC=CC=C1 KCFYEAOKVJSACF-UHFFFAOYSA-N 0.000 description 1
• YNWVFADWVLCOPU-MAUPQMMJSA-N uniconazole P Chemical compound C1=NC=NN1/C([C@@H](O)C(C)(C)C)=C/C1=CC=C(Cl)C=C1 YNWVFADWVLCOPU-MAUPQMMJSA-N 0.000 description 1
• 210000004291 uterus Anatomy 0.000 description 1
• JARYYMUOCXVXNK-IMTORBKUSA-N validamycin Chemical compound N([C@H]1C[C@@H]([C@H]([C@H](O)[C@H]1O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)CO)[C@H]1C=C(CO)[C@H](O)[C@H](O)[C@H]1O JARYYMUOCXVXNK-IMTORBKUSA-N 0.000 description 1
• DBXFMOWZRXXBRN-LWKPJOBUSA-N valifenalate Chemical compound CC(C)OC(=O)N[C@@H](C(C)C)C(=O)NC(CC(=O)OC)C1=CC=C(Cl)C=C1 DBXFMOWZRXXBRN-LWKPJOBUSA-N 0.000 description 1
• 235000015192 vegetable juice Nutrition 0.000 description 1
• 239000003981 vehicle Substances 0.000 description 1
• 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
• 229920002554 vinyl polymer Polymers 0.000 description 1
• 230000000007 visual effect Effects 0.000 description 1
• 208000010484 vulvovaginitis Diseases 0.000 description 1
• 238000005406 washing Methods 0.000 description 1
• 230000003313 weakening effect Effects 0.000 description 1
• 230000036642 wellbeing Effects 0.000 description 1
• 238000009736 wetting Methods 0.000 description 1
• 239000000080 wetting agent Substances 0.000 description 1
• 230000029663 wound healing Effects 0.000 description 1
• 241000228158 x Triticosecale Species 0.000 description 1
• 239000012138 yeast extract Substances 0.000 description 1
• 229960000523 zalcitabine Drugs 0.000 description 1
• ARAIBEBZBOPLMB-UFGQHTETSA-N zanamivir Chemical compound CC(=O)N[C@@H]1[C@@H](N=C(N)N)C=C(C(O)=O)O[C@H]1[C@H](O)[C@H](O)CO ARAIBEBZBOPLMB-UFGQHTETSA-N 0.000 description 1
• 229960001028 zanamivir Drugs 0.000 description 1
• 229960002555 zidovudine Drugs 0.000 description 1
• HBOMLICNUCNMMY-XLPZGREQSA-N zidovudine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-XLPZGREQSA-N 0.000 description 1
• FJBGIXKIXPUXBY-UHFFFAOYSA-N {2-[3-(4-chlorophenyl)propyl]-2,4,4-trimethyl-1,3-oxazolidin-3-yl}(imidazol-1-yl)methanone Chemical compound C1=CN=CN1C(=O)N1C(C)(C)COC1(C)CCCC1=CC=C(Cl)C=C1 FJBGIXKIXPUXBY-UHFFFAOYSA-N 0.000 description 1