JP6180514B2 - 補体経路モジュレーターおよびその使用 - Google Patents
補体経路モジュレーターおよびその使用 Download PDFInfo
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- JP6180514B2 JP6180514B2 JP2015509561A JP2015509561A JP6180514B2 JP 6180514 B2 JP6180514 B2 JP 6180514B2 JP 2015509561 A JP2015509561 A JP 2015509561A JP 2015509561 A JP2015509561 A JP 2015509561A JP 6180514 B2 JP6180514 B2 JP 6180514B2
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- Prior art keywords
- methyl
- benzo
- indol
- carbonitrile
- imidazole
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Landscapes
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Cited By (1)
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| JP2016526576A (ja) * | 2013-07-15 | 2016-09-05 | ノバルティス アーゲー | ピペリジニル−インドール誘導体および補体因子ｂ阻害剤としてのその使用 |
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| US9475806B2 (en) | 2013-03-14 | 2016-10-25 | Novartis Ag | Complement factor B inhibitors and uses there of |
| CN105849090A (zh) * | 2013-10-30 | 2016-08-10 | 诺华股份有限公司 | 2-苄基-苯并咪唑补体因子b抑制剂及其用途 |
| CN103755622A (zh) * | 2013-12-25 | 2014-04-30 | 华东理工大学 | 合成4,5,6,7-四氘代吲哚-3-乙酸的方法 |
| AR106018A1 (es) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos |
| WO2017035408A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Compounds for treatment of immune and inflammatory disorders |
| TWI747873B (zh) | 2016-02-01 | 2021-12-01 | 美商百歐克斯製藥公司 | 苯并吡唑化合物及其類似物 |
| SG11201811491YA (en) * | 2016-06-27 | 2019-01-30 | Achillion Pharmaceuticals Inc | Quinazoline and indole compounds to treat medical disorders |
| CN110603252A (zh) | 2017-03-01 | 2019-12-20 | 艾其林医药公司 | 用于治疗医学障碍的芳基、杂芳基和杂环药物化合物 |
| TWI873092B (zh) | 2018-04-06 | 2025-02-21 | 美商百歐克斯製藥公司 | 取代的苯并呋喃、苯并吡咯、苯并噻吩及結構相關的補體抑制劑 |
| US20230022157A1 (en) | 2018-08-20 | 2023-01-26 | Achillion Pharmaceuticals, Inc. | Pharmaceutical compounds for the treatment of complement factor d medical disorders |
| JP7443375B2 (ja) | 2018-09-06 | 2024-03-05 | アキリオン ファーマシューティカルズ， インコーポレーテッド | 医学的障害の治療のための大環状化合物 |
| WO2020051538A1 (en) | 2018-09-06 | 2020-03-12 | Achillion Pharmaceuticals, Inc. | Morphic forms of complement factor d inhibitors |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016526576A (ja) * | 2013-07-15 | 2016-09-05 | ノバルティス アーゲー | ピペリジニル−インドール誘導体および補体因子ｂ阻害剤としてのその使用 |
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| AR090945A1 (es) | 2014-12-17 |
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| SG11201406973PA (en) | 2014-12-30 |
| CN104603127A (zh) | 2015-05-06 |
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