JP6155194B2 - 良性甲状腺新生物と悪性甲状腺新生物を区別するためのバイオマーカーとしてのmiRNA - Google Patents
良性甲状腺新生物と悪性甲状腺新生物を区別するためのバイオマーカーとしてのmiRNA Download PDFInfo
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- JP6155194B2 JP6155194B2 JP2013540026A JP2013540026A JP6155194B2 JP 6155194 B2 JP6155194 B2 JP 6155194B2 JP 2013540026 A JP2013540026 A JP 2013540026A JP 2013540026 A JP2013540026 A JP 2013540026A JP 6155194 B2 JP6155194 B2 JP 6155194B2
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
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- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
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- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41477810P | 2010-11-17 | 2010-11-17 | |
| US61/414,778 | 2010-11-17 | ||
| PCT/US2011/061237 WO2012068400A2 (en) | 2010-11-17 | 2011-11-17 | Mirnas as biomarkers for distinguishing benign from malignant thyroid neoplasms |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013544098A JP2013544098A (ja) | 2013-12-12 |
| JP2013544098A5 JP2013544098A5 (enExample) | 2015-08-06 |
| JP6155194B2 true JP6155194B2 (ja) | 2017-06-28 |
Family
ID=45217687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013540026A Active JP6155194B2 (ja) | 2010-11-17 | 2011-11-17 | 良性甲状腺新生物と悪性甲状腺新生物を区別するためのバイオマーカーとしてのmiRNA |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US10150999B2 (enExample) |
| EP (2) | EP2640851A2 (enExample) |
| JP (1) | JP6155194B2 (enExample) |
| AU (1) | AU2011329772B2 (enExample) |
| BR (1) | BR112013012265A2 (enExample) |
| CA (1) | CA2817882C (enExample) |
| ES (1) | ES2629890T3 (enExample) |
| IL (2) | IL226356B (enExample) |
| WO (1) | WO2012068400A2 (enExample) |
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| US10407731B2 (en) | 2008-05-30 | 2019-09-10 | Mayo Foundation For Medical Education And Research | Biomarker panels for predicting prostate cancer outcomes |
| US9495515B1 (en) | 2009-12-09 | 2016-11-15 | Veracyte, Inc. | Algorithms for disease diagnostics |
| US10236078B2 (en) | 2008-11-17 | 2019-03-19 | Veracyte, Inc. | Methods for processing or analyzing a sample of thyroid tissue |
| US9074258B2 (en) | 2009-03-04 | 2015-07-07 | Genomedx Biosciences Inc. | Compositions and methods for classifying thyroid nodule disease |
| JP6078339B2 (ja) | 2009-05-07 | 2017-02-08 | ベラサイト インコーポレイテッド | 甲状腺状態の診断のための方法および組成物 |
| US10446272B2 (en) | 2009-12-09 | 2019-10-15 | Veracyte, Inc. | Methods and compositions for classification of samples |
| JP6155194B2 (ja) | 2010-11-17 | 2017-06-28 | インターペース ダイアグノスティックス リミテッド ライアビリティ カンパニー | 良性甲状腺新生物と悪性甲状腺新生物を区別するためのバイオマーカーとしてのmiRNA |
| US20130267443A1 (en) | 2010-11-19 | 2013-10-10 | The Regents Of The University Of Michigan | ncRNA AND USES THEREOF |
| EP2771487A1 (en) * | 2011-10-27 | 2014-09-03 | Asuragen, INC. | Mirnas as diagnostic biomarkers to distinguish benign from malignant thyroid tumors |
| WO2013090620A1 (en) | 2011-12-13 | 2013-06-20 | Genomedx Biosciences, Inc. | Cancer diagnostics using non-coding transcripts |
| ES2945036T3 (es) | 2012-08-16 | 2023-06-28 | Veracyte Sd Inc | Pronóstico del cáncer de próstata mediante biomarcadores |
| US10526655B2 (en) | 2013-03-14 | 2020-01-07 | Veracyte, Inc. | Methods for evaluating COPD status |
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| PL406033A1 (pl) * | 2013-11-14 | 2015-05-25 | Warszawski Uniwersytet Medyczny | Sposób diagnozowania raka brodawkowatego tarczycy, zastosowanie markera mikroRNA do diagnozowania nowotworu tarczycy, oceny stopnia zaawansowania choroby oraz oceny podatności pacjenta i/lub choroby na zaproponowane leczenie oraz zawierający takie markery zestaw diagnostyczny |
| US12297505B2 (en) | 2014-07-14 | 2025-05-13 | Veracyte, Inc. | Algorithms for disease diagnostics |
| RU2569154C1 (ru) * | 2014-10-08 | 2015-11-20 | Федеральное государственное бюджетное учреждение науки Институт молекулярной и клеточной биологии Сибирского отделения Российской академии наук (ИМКБ СО РАН) | Способ дифференциальной диагностики новообразований щитовидной железы человека |
| EP3770274A1 (en) | 2014-11-05 | 2021-01-27 | Veracyte, Inc. | Systems and methods of diagnosing idiopathic pulmonary fibrosis on transbronchial biopsies using machine learning and high dimensional transcriptional data |
| RU2718534C2 (ru) | 2015-06-05 | 2020-04-08 | Мираджен Терапьютикс, Инк. | Ингибиторы mir-155 для лечения кожной t-клеточной лимфомы (ctcl) |
| WO2017134115A1 (en) * | 2016-02-01 | 2017-08-10 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Method for determining responsiveness to vandetanib in a patient suffering from medullary thyroid carcinoma |
| US11414708B2 (en) | 2016-08-24 | 2022-08-16 | Decipher Biosciences, Inc. | Use of genomic signatures to predict responsiveness of patients with prostate cancer to post-operative radiation therapy |
| AU2018210695B2 (en) | 2017-01-20 | 2024-07-18 | The University Of British Columbia | Molecular subtyping, prognosis, and treatment of bladder cancer |
| US11873532B2 (en) | 2017-03-09 | 2024-01-16 | Decipher Biosciences, Inc. | Subtyping prostate cancer to predict response to hormone therapy |
| WO2018205035A1 (en) | 2017-05-12 | 2018-11-15 | Genomedx Biosciences, Inc | Genetic signatures to predict prostate cancer metastasis and identify tumor agressiveness |
| US11217329B1 (en) | 2017-06-23 | 2022-01-04 | Veracyte, Inc. | Methods and systems for determining biological sample integrity |
| EP4265725A3 (en) | 2017-11-09 | 2023-12-27 | Purmx Therapeutics, Inc. | Pharmaceutical composition comprising mirna-3140 for use in treating cancer |
| CN109055541B (zh) * | 2018-09-26 | 2020-08-28 | 上海市精神卫生中心(上海市心理咨询培训中心) | Ad所致mci诊断标志物及其应用 |
| CN110241215B (zh) * | 2019-07-03 | 2020-05-19 | 上海润安医学科技有限公司 | 一种用于检测甲状腺结节良恶性相关基因变异的引物及试剂盒 |
| CN110468204A (zh) * | 2019-08-09 | 2019-11-19 | 深圳市第二人民医院 | 生物标志物及其在制备诊断ptc的产品中的应用 |
| WO2022055316A1 (ko) * | 2020-09-14 | 2022-03-17 | 연세대학교 산학협력단 | 양성 종양 또는 결절로부터 암을 구분하기 위한 바이오마커 |
| KR102426397B1 (ko) * | 2020-09-14 | 2022-07-28 | 연세대학교 산학협력단 | 암 진단의 정확도를 높이기 위한 유전자 발현 수준의 보정 방법 |
| RU2757347C1 (ru) * | 2021-02-08 | 2021-10-13 | Сергей Евгеньевич Титов | Способ дифференциальной диагностики узловых образований щитовидной железы человека |
| CN116769922B (zh) * | 2023-08-24 | 2023-11-24 | 四川大学华西医院 | 检测循环sEV RNA试剂的用途、试剂盒和诊断系统 |
| CN116987791B (zh) * | 2023-09-22 | 2023-12-22 | 润安医学科技(苏州)有限公司 | 一组血浆标志物在甲状腺结节良恶性鉴别中的应用 |
| CN118248319B (zh) * | 2024-02-20 | 2024-12-03 | 上海睿璟生物科技有限公司 | 基于基因组变异与异常表达结合的甲状腺结节良恶性辅助诊断系统 |
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| US20190309370A1 (en) | 2019-10-10 |
| US20220213551A1 (en) | 2022-07-07 |
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| CA2817882C (en) | 2022-08-23 |
| AU2011329772B2 (en) | 2017-05-04 |
| JP2013544098A (ja) | 2013-12-12 |
| CA2817882A1 (en) | 2012-05-24 |
| EP2772550A1 (en) | 2014-09-03 |
| IL226356A0 (en) | 2013-07-31 |
| US11118231B2 (en) | 2021-09-14 |
| IL258076A (en) | 2018-05-31 |
| US20240417811A1 (en) | 2024-12-19 |
| US10150999B2 (en) | 2018-12-11 |
| WO2012068400A3 (en) | 2013-01-03 |
| EP2772550B1 (en) | 2017-03-29 |
| US20120157334A1 (en) | 2012-06-21 |
| EP2640851A2 (en) | 2013-09-25 |
| BR112013012265A2 (pt) | 2016-08-02 |
| ES2629890T3 (es) | 2017-08-16 |
| AU2011329772A1 (en) | 2013-05-30 |
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