CA2817882C - Mirnas as biomarkers for distinguishing benign from malignant thyroid neoplasms - Google Patents

Mirnas as biomarkers for distinguishing benign from malignant thyroid neoplasms Download PDF

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Publication number
CA2817882C
CA2817882C CA2817882A CA2817882A CA2817882C CA 2817882 C CA2817882 C CA 2817882C CA 2817882 A CA2817882 A CA 2817882A CA 2817882 A CA2817882 A CA 2817882A CA 2817882 C CA2817882 C CA 2817882C
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mir
hsa
mirna
thyroid
mirnas
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English (en)
French (fr)
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CA2817882A1 (en
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Sylvie Beaudenon-Huibregtse
Ashish Choudhary
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INTERPACE DIAGNOSTICS LLC
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INTERPACE DIAGNOSTICS LLC
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CA2817882A 2010-11-17 2011-11-17 Mirnas as biomarkers for distinguishing benign from malignant thyroid neoplasms Active CA2817882C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41477810P 2010-11-17 2010-11-17
US61/414,778 2010-11-17
PCT/US2011/061237 WO2012068400A2 (en) 2010-11-17 2011-11-17 Mirnas as biomarkers for distinguishing benign from malignant thyroid neoplasms

Publications (2)

Publication Number Publication Date
CA2817882A1 CA2817882A1 (en) 2012-05-24
CA2817882C true CA2817882C (en) 2022-08-23

Family

ID=45217687

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2817882A Active CA2817882C (en) 2010-11-17 2011-11-17 Mirnas as biomarkers for distinguishing benign from malignant thyroid neoplasms

Country Status (9)

Country Link
US (4) US10150999B2 (enExample)
EP (2) EP2640851A2 (enExample)
JP (1) JP6155194B2 (enExample)
AU (1) AU2011329772B2 (enExample)
BR (1) BR112013012265A2 (enExample)
CA (1) CA2817882C (enExample)
ES (1) ES2629890T3 (enExample)
IL (2) IL226356B (enExample)
WO (1) WO2012068400A2 (enExample)

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US10236078B2 (en) 2008-11-17 2019-03-19 Veracyte, Inc. Methods for processing or analyzing a sample of thyroid tissue
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US20130267443A1 (en) 2010-11-19 2013-10-10 The Regents Of The University Of Michigan ncRNA AND USES THEREOF
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CN109055541B (zh) * 2018-09-26 2020-08-28 上海市精神卫生中心（上海市心理咨询培训中心） Ad所致mci诊断标志物及其应用
CN110241215B (zh) * 2019-07-03 2020-05-19 上海润安医学科技有限公司 一种用于检测甲状腺结节良恶性相关基因变异的引物及试剂盒
CN110468204A (zh) * 2019-08-09 2019-11-19 深圳市第二人民医院 生物标志物及其在制备诊断ptc的产品中的应用
WO2022055316A1 (ko) * 2020-09-14 2022-03-17 연세대학교 산학협력단 양성 종양 또는 결절로부터 암을 구분하기 위한 바이오마커
KR102426397B1 (ko) * 2020-09-14 2022-07-28 연세대학교 산학협력단 암 진단의 정확도를 높이기 위한 유전자 발현 수준의 보정 방법
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CN116769922B (zh) * 2023-08-24 2023-11-24 四川大学华西医院 检测循环sEV RNA试剂的用途、试剂盒和诊断系统
CN116987791B (zh) * 2023-09-22 2023-12-22 润安医学科技(苏州)有限公司 一组血浆标志物在甲状腺结节良恶性鉴别中的应用
CN118248319B (zh) * 2024-02-20 2024-12-03 上海睿璟生物科技有限公司 基于基因组变异与异常表达结合的甲状腺结节良恶性辅助诊断系统

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