JP6148256B2 - 高分解能３ｄ蛍光顕微鏡法のための顕微鏡および方法 - Google Patents

高分解能３ｄ蛍光顕微鏡法のための顕微鏡および方法 Download PDF

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JP6148256B2
JP6148256B2 JP2014552544A JP2014552544A JP6148256B2 JP 6148256 B2 JP6148256 B2 JP 6148256B2 JP 2014552544 A JP2014552544 A JP 2014552544A JP 2014552544 A JP2014552544 A JP 2014552544A JP 6148256 B2 JP6148256 B2 JP 6148256B2
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JP2015505620A (ja
JP2015505620A5 (enExample
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カルクブレナー、トーマス
ヴォレシェンスキー、ラルフ
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Carl Zeiss Microscopy GmbH
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    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/361—Optical details, e.g. image relay to the camera or image sensor
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365—Control or image processing arrangements for digital or video microscopes
    • G02B21/367—Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/58—Optics for apodization or superresolution; Optical synthetic aperture systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/061—Sources
    • G01N2201/06113—Coherent sources; lasers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing

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  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Multimedia (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Microscoopes, Condenser (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
JP2014552544A 2012-01-24 2012-12-13 高分解能３ｄ蛍光顕微鏡法のための顕微鏡および方法 Active JP6148256B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102012201003.3A DE102012201003B4 (de) 2012-01-24 2012-01-24 Mikroskop und Verfahren für die hochauflösende 3-D Fluoreszenzmikroskopie
DE102012201003.3 2012-01-24
PCT/EP2012/075465 WO2013110408A1 (de) 2012-01-24 2012-12-13 Mikroskop und verfahren für die hochauflösende 3-d fluoreszenzmikroskopie

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JP2015505620A JP2015505620A (ja) 2015-02-23
JP2015505620A5 JP2015505620A5 (enExample) 2017-04-27
JP6148256B2 true JP6148256B2 (ja) 2017-06-14

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US (1) US9885860B2 (enExample)
EP (1) EP2807515B1 (enExample)
JP (1) JP6148256B2 (enExample)
DE (1) DE102012201003B4 (enExample)
WO (1) WO2013110408A1 (enExample)

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Publication number Priority date Publication date Assignee Title
KR102719078B1 (ko) 2021-10-26 2024-10-24 포항공과대학교 산학협력단 목시플록사신을 이용한 생체조직표면 세포 영상검사장치 및 목시플록사신을 이용한 생체조직표면 세포 영상검사방법

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WO2017090210A1 (ja) * 2015-11-27 2017-06-01 株式会社ニコン 顕微鏡、観察方法、及び画像処理プログラム
CN109154569A (zh) 2016-02-12 2019-01-04 麻省理工学院 用于对未切片组织样本成像的方法和装置
DE102017129519B4 (de) * 2017-12-12 2020-08-06 Technische Universität Ilmenau Anordnung und Verfahren zur simultanen Messung der Fluoreszenz einzelner Schichten in einem Schichtsystem, beispielsweise dem Augenhintergrund
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102719078B1 (ko) 2021-10-26 2024-10-24 포항공과대학교 산학협력단 목시플록사신을 이용한 생체조직표면 세포 영상검사장치 및 목시플록사신을 이용한 생체조직표면 세포 영상검사방법

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EP2807515B1 (de) 2016-03-09
EP2807515A1 (de) 2014-12-03
JP2015505620A (ja) 2015-02-23
DE102012201003A1 (de) 2013-07-25
US20150160446A1 (en) 2015-06-11
DE102012201003B4 (de) 2024-07-25
WO2013110408A1 (de) 2013-08-01
US9885860B2 (en) 2018-02-06

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