JP6145946B2 - 併用als療法 - Google Patents

併用als療法 Download PDF

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Publication number
JP6145946B2
JP6145946B2 JP2014520335A JP2014520335A JP6145946B2 JP 6145946 B2 JP6145946 B2 JP 6145946B2 JP 2014520335 A JP2014520335 A JP 2014520335A JP 2014520335 A JP2014520335 A JP 2014520335A JP 6145946 B2 JP6145946 B2 JP 6145946B2
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JP
Japan
Prior art keywords
riluzole
composition
administered
combination
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP2014520335A
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English (en)
Japanese (ja)
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JP2014520856A5 (show.php
JP2014520856A (ja
Inventor
ジェシー シダーバーム,
ジェシー シダーバーム,
マオ, ジョン
ジョン マオ,
ファディー マリック,
ファディー マリック,
アンドリュー エー. ウォルフ,
アンドリュー エー. ウォルフ,
Original Assignee
サイトキネティックス, インコーポレイテッド
サイトキネティックス, インコーポレイテッド
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Publication of JP2014520856A5 publication Critical patent/JP2014520856A5/ja
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/428Thiazoles condensed with carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2014520335A 2011-07-13 2012-07-12 併用als療法 Expired - Fee Related JP6145946B2 (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201161507381P 2011-07-13 2011-07-13
US61/507,381 2011-07-13
US201161544533P 2011-10-07 2011-10-07
US61/544,533 2011-10-07
US201261637770P 2012-04-24 2012-04-24
US201261637759P 2012-04-24 2012-04-24
US61/637,770 2012-04-24
US61/637,759 2012-04-24
US201261646699P 2012-05-14 2012-05-14
US61/646,699 2012-05-14
PCT/US2012/046523 WO2013010015A2 (en) 2011-07-13 2012-07-12 Combination als therapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017090313A Division JP2017128610A (ja) 2011-07-13 2017-04-28 併用als療法

Publications (3)

Publication Number Publication Date
JP2014520856A JP2014520856A (ja) 2014-08-25
JP2014520856A5 JP2014520856A5 (show.php) 2015-09-03
JP6145946B2 true JP6145946B2 (ja) 2017-06-14

Family

ID=47506929

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2014520335A Expired - Fee Related JP6145946B2 (ja) 2011-07-13 2012-07-12 併用als療法
JP2017090313A Pending JP2017128610A (ja) 2011-07-13 2017-04-28 併用als療法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2017090313A Pending JP2017128610A (ja) 2011-07-13 2017-04-28 併用als療法

Country Status (16)

Country Link
US (1) US10272082B2 (show.php)
EP (1) EP2731611B1 (show.php)
JP (2) JP6145946B2 (show.php)
KR (1) KR101951220B1 (show.php)
CN (2) CN109316480A (show.php)
AU (2) AU2012281042B2 (show.php)
BR (1) BR112014000742A2 (show.php)
CA (1) CA2849213A1 (show.php)
EA (2) EA028060B1 (show.php)
HK (1) HK1197178A1 (show.php)
IL (1) IL230391B (show.php)
IN (1) IN2014DN00200A (show.php)
PH (1) PH12014500094A1 (show.php)
SG (1) SG10201605707UA (show.php)
WO (1) WO2013010015A2 (show.php)
ZA (1) ZA201400236B (show.php)

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PT3240538T (pt) 2016-03-25 2021-12-07 Ab Science Uso de masitinib para tratamento de uma subpopulação de pacientes com esclerose lateral amiotrófica
EP4031135A4 (en) * 2019-09-20 2023-10-18 Icahn School of Medicine at Mount Sinai CONTROLLED RELEASE FORMULATIONS OF RILUZOLE AND USES THEREOF

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Also Published As

Publication number Publication date
PH12014500094A1 (en) 2014-03-17
HK1197178A1 (en) 2015-01-09
ZA201400236B (en) 2014-10-29
SG10201605707UA (en) 2016-09-29
EA028060B1 (ru) 2017-10-31
WO2013010015A3 (en) 2014-05-15
US10272082B2 (en) 2019-04-30
AU2012281042B2 (en) 2016-07-14
NZ619924A (en) 2016-02-26
CN109316480A (zh) 2019-02-12
EP2731611A4 (en) 2015-02-18
WO2013010015A2 (en) 2013-01-17
KR20140074270A (ko) 2014-06-17
EA201791043A1 (ru) 2017-09-29
IN2014DN00200A (show.php) 2015-06-05
EA201490011A1 (ru) 2014-08-29
AU2012281042A1 (en) 2014-01-30
KR101951220B1 (ko) 2019-02-22
JP2017128610A (ja) 2017-07-27
CN104039148A (zh) 2014-09-10
CA2849213A1 (en) 2013-01-17
EP2731611A2 (en) 2014-05-21
IL230391B (en) 2019-03-31
BR112014000742A2 (pt) 2016-08-23
US20140243344A1 (en) 2014-08-28
JP2014520856A (ja) 2014-08-25
AU2016244263A1 (en) 2016-11-03
EP2731611B1 (en) 2019-09-18

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