JP6141850B2 - 老眼、弱度の遠視、および不正乱視を治療する組成物およびその治療方法 - Google Patents

老眼、弱度の遠視、および不正乱視を治療する組成物およびその治療方法 Download PDF

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JP6141850B2
JP6141850B2 JP2014531333A JP2014531333A JP6141850B2 JP 6141850 B2 JP6141850 B2 JP 6141850B2 JP 2014531333 A JP2014531333 A JP 2014531333A JP 2014531333 A JP2014531333 A JP 2014531333A JP 6141850 B2 JP6141850 B2 JP 6141850B2
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pilocarpine
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JP2014533238A (ja
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ファウン カルロス アバド
ファウン カルロス アバド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541—Non-condensed thiazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
JP2014531333A 2011-09-20 2012-09-19 老眼、弱度の遠視、および不正乱視を治療する組成物およびその治療方法 Active JP6141850B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161536921P 2011-09-20 2011-09-20
US61/536,921 2011-09-20
PCT/IB2012/002335 WO2013041967A2 (fr) 2011-09-20 2012-09-19 Compositions et procédés pour traiter la presbytie, l'hypermétropie légère et l'astigmatisme irrégulier

Publications (2)

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JP2014533238A JP2014533238A (ja) 2014-12-11
JP6141850B2 true JP6141850B2 (ja) 2017-06-07

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JP2014531333A Active JP6141850B2 (ja) 2011-09-20 2012-09-19 老眼、弱度の遠視、および不正乱視を治療する組成物およびその治療方法

Country Status (23)

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US (6) US9579308B2 (fr)
EP (3) EP2758047B1 (fr)
JP (1) JP6141850B2 (fr)
KR (1) KR102017916B1 (fr)
CN (1) CN104093404B (fr)
AU (2) AU2012311239B2 (fr)
BR (1) BR112014006607A2 (fr)
CA (2) CA2849366C (fr)
CL (1) CL2014000689A1 (fr)
CO (1) CO7000769A2 (fr)
DK (1) DK2758047T3 (fr)
ES (1) ES2715296T3 (fr)
HK (1) HK1198426A1 (fr)
IL (1) IL231631B (fr)
IN (1) IN2014CN02961A (fr)
MX (1) MX357635B (fr)
MY (1) MY168643A (fr)
RU (1) RU2630968C2 (fr)
SG (1) SG11201400828RA (fr)
TR (1) TR201903465T4 (fr)
UA (1) UA113525C2 (fr)
WO (1) WO2013041967A2 (fr)
ZA (1) ZA201402049B (fr)

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Publication number Publication date
US9579308B2 (en) 2017-02-28
EP4272743A3 (fr) 2024-07-10
JP2014533238A (ja) 2014-12-11
ES2715296T3 (es) 2019-06-03
KR102017916B1 (ko) 2019-09-03
MX2014003421A (es) 2014-10-17
EP3517111A3 (fr) 2019-12-11
US20180333392A1 (en) 2018-11-22
CO7000769A2 (es) 2014-07-21
US20200069651A1 (en) 2020-03-05
CN104093404A (zh) 2014-10-08
US9301933B2 (en) 2016-04-05
EP2758047B1 (fr) 2018-12-19
RU2630968C2 (ru) 2017-09-15
MY168643A (en) 2018-11-27
BR112014006607A2 (pt) 2017-04-25
RU2014115439A (ru) 2015-10-27
IN2014CN02961A (fr) 2015-07-03
AU2012311239A1 (en) 2014-04-10
NZ623037A (en) 2016-07-29
UA113525C2 (xx) 2017-02-10
CA3049795A1 (fr) 2013-03-28
SG11201400828RA (en) 2014-07-30
CA2849366C (fr) 2019-09-10
CN104093404B (zh) 2016-12-07
EP3517111A2 (fr) 2019-07-31
AU2012311239B2 (en) 2017-10-19
US20220040152A1 (en) 2022-02-10
WO2013041967A3 (fr) 2013-08-01
KR20140076587A (ko) 2014-06-20
US20140113946A1 (en) 2014-04-24
IL231631A0 (en) 2014-05-28
MX357635B (es) 2018-07-17
US20140200211A1 (en) 2014-07-17
HK1198426A1 (en) 2015-04-24
IL231631B (en) 2019-07-31
WO2013041967A2 (fr) 2013-03-28
EP2758047A2 (fr) 2014-07-30
WO2013041967A9 (fr) 2013-06-13
ZA201402049B (en) 2015-11-25
AU2017239563A1 (en) 2017-10-26
US20160310466A1 (en) 2016-10-27
DK2758047T3 (en) 2019-04-01
TR201903465T4 (tr) 2019-04-22
EP4272743A2 (fr) 2023-11-08
CL2014000689A1 (es) 2015-01-09
AU2017239563B2 (en) 2019-09-26
CA2849366A1 (fr) 2013-03-28

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