JP6126010B2 - 外科インプラント - Google Patents
外科インプラント Download PDFInfo
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- JP6126010B2 JP6126010B2 JP2013540951A JP2013540951A JP6126010B2 JP 6126010 B2 JP6126010 B2 JP 6126010B2 JP 2013540951 A JP2013540951 A JP 2013540951A JP 2013540951 A JP2013540951 A JP 2013540951A JP 6126010 B2 JP6126010 B2 JP 6126010B2
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- plate
- staple
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- 239000007943 implant Substances 0.000 title claims description 49
- 210000000988 bone and bone Anatomy 0.000 claims description 37
- 210000004872 soft tissue Anatomy 0.000 claims description 23
- 239000000463 material Substances 0.000 claims description 17
- 230000013011 mating Effects 0.000 claims description 2
- 230000001939 inductive effect Effects 0.000 claims 1
- 230000002093 peripheral effect Effects 0.000 claims 1
- 210000002414 leg Anatomy 0.000 description 45
- 210000003041 ligament Anatomy 0.000 description 11
- 210000002435 tendon Anatomy 0.000 description 10
- 238000007373 indentation Methods 0.000 description 5
- 238000010586 diagram Methods 0.000 description 4
- 238000003780 insertion Methods 0.000 description 4
- 230000037431 insertion Effects 0.000 description 4
- 238000006073 displacement reaction Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000003825 pressing Methods 0.000 description 3
- 239000010935 stainless steel Substances 0.000 description 3
- 229910001220 stainless steel Inorganic materials 0.000 description 3
- 239000004698 Polyethylene Substances 0.000 description 2
- 229910000831 Steel Inorganic materials 0.000 description 2
- 229910045601 alloy Inorganic materials 0.000 description 2
- 239000000956 alloy Substances 0.000 description 2
- 238000005520 cutting process Methods 0.000 description 2
- 238000005304 joining Methods 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 2
- -1 polyethylene Polymers 0.000 description 2
- 229920000573 polyethylene Polymers 0.000 description 2
- 239000004926 polymethyl methacrylate Substances 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 239000010959 steel Substances 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 229910000684 Cobalt-chrome Inorganic materials 0.000 description 1
- 206010023204 Joint dislocation Diseases 0.000 description 1
- JVTAAEKCZFNVCJ-REOHCLBHSA-N L-lactic acid Chemical compound C[C@H](O)C(O)=O JVTAAEKCZFNVCJ-REOHCLBHSA-N 0.000 description 1
- 208000034693 Laceration Diseases 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 239000004696 Poly ether ether ketone Substances 0.000 description 1
- 229910001069 Ti alloy Inorganic materials 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 210000000142 acromioclavicular joint Anatomy 0.000 description 1
- JUPQTSLXMOCDHR-UHFFFAOYSA-N benzene-1,4-diol;bis(4-fluorophenyl)methanone Chemical compound OC1=CC=C(O)C=C1.C1=CC(F)=CC=C1C(=O)C1=CC=C(F)C=C1 JUPQTSLXMOCDHR-UHFFFAOYSA-N 0.000 description 1
- 239000010952 cobalt-chrome Substances 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
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- 210000000852 deltoid muscle Anatomy 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 210000000426 patellar ligament Anatomy 0.000 description 1
- 229920001432 poly(L-lactide) Polymers 0.000 description 1
- 229920001606 poly(lactic acid-co-glycolic acid) Polymers 0.000 description 1
- 229920006260 polyaryletherketone Polymers 0.000 description 1
- 229920002530 polyetherether ketone Polymers 0.000 description 1
- 238000007634 remodeling Methods 0.000 description 1
- 210000000513 rotator cuff Anatomy 0.000 description 1
Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/064—Surgical staples, i.e. penetrating the tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/064—Surgical staples, i.e. penetrating the tissue
- A61B17/0642—Surgical staples, i.e. penetrating the tissue for bones, e.g. for osteosynthesis or connecting tendon to bone
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/84—Fasteners therefor or fasteners being internal fixation devices
- A61B17/844—Fasteners therefor or fasteners being internal fixation devices with expandable anchors or anchors having movable parts
-
- A—HUMAN NECESSITIES
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- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/064—Surgical staples, i.e. penetrating the tissue
- A61B17/0644—Surgical staples, i.e. penetrating the tissue penetrating the tissue, deformable to closed position
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/068—Surgical staplers, e.g. containing multiple staples or clamps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/068—Surgical staplers, e.g. containing multiple staples or clamps
- A61B17/0682—Surgical staplers, e.g. containing multiple staples or clamps for applying U-shaped staples or clamps, e.g. without a forming anvil
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- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/08—Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound
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- A—HUMAN NECESSITIES
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
- A61B17/92—Impactors or extractors, e.g. for removing intramedullary devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
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- A—HUMAN NECESSITIES
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- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
- A61F2/0805—Implements for inserting tendons or ligaments
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
- A61F2/0811—Fixation devices for tendons or ligaments
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/064—Surgical staples, i.e. penetrating the tissue
- A61B17/0643—Surgical staples, i.e. penetrating the tissue with separate closing member, e.g. for interlocking with staple
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00646—Type of implements
- A61B2017/00668—Type of implements the implement being a tack or a staple
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/064—Surgical staples, i.e. penetrating the tissue
- A61B2017/0641—Surgical staples, i.e. penetrating the tissue having at least three legs as part of one single body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
- A61F2/0811—Fixation devices for tendons or ligaments
- A61F2002/0817—Structure of the anchor
- A61F2002/0823—Modular anchors comprising a plurality of separate parts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
- A61F2/0811—Fixation devices for tendons or ligaments
- A61F2002/0847—Mode of fixation of anchor to tendon or ligament
- A61F2002/0858—Fixation of tendon or ligament between anchor and bone, e.g. interference screws, wedges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
- A61F2/0811—Fixation devices for tendons or ligaments
- A61F2002/0876—Position of anchor in respect to the bone
- A61F2002/0888—Anchor in or on a blind hole or on the bone surface without formation of a tunnel
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B25—HAND TOOLS; PORTABLE POWER-DRIVEN TOOLS; MANIPULATORS
- B25D—PERCUSSIVE TOOLS
- B25D1/00—Hand hammers; Hammer heads of special shape or materials
- B25D1/16—Hand hammers; Hammer heads of special shape or materials having the impacting head in the form of a sleeve slidable on a shaft, e.g. hammers for driving a valve or draw-off tube into a barrel
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
- Rehabilitation Therapy (AREA)
- Neurology (AREA)
- Surgical Instruments (AREA)
- Prostheses (AREA)
Description
プレートの下面を骨に対して圧接することによって骨の表面に柔軟組織を固定し;
露出したプレートの上面からプレートを介してあるいはプレートの側方でステープルの脚部を打ち込み従って脚部がプレートの下側で骨内に固定されて柔軟組織がプレートと骨の間に挟み込まれるようにする。
ステープル12の中央開口部17にねじ山が切られていない。
Claims (19)
- ブリッジ部と前記ブリッジ部から延伸する複数の脚部を有するステープルを備えていて、前記ブリッジ部が同ブリッジ部を貫通して延在する中央開口部を有してなり;
さらに上面と下面を有するプレートを備え、前記プレートは前記ステープルから分離されていて、
前記ステープルが引張強度を有する材料からなり、前記プレートが前記ステープルの引張強度よりも低い引張強度を有する材料からなり、
前記ステープルの脚部が前記プレートにおける厚さを有する部分を穿通して骨内に打ち込まれた際に前記ステープルがそのステープルのブリッジ部と骨の間に位置したプレートと共に骨に固定可能であるように、前記脚部が前記プレートと整合可能である、
外科インプラント。 - ステープルの脚部がプレートを穿通して配置されている際に前記プレートが前記ステープルの中央開口部と軸方向に整合する中央開口部を有し、前記ステープルの中央開口部にねじ山が切られていない請求項1記載の外科インプラント。
- ステープルの脚部がプレートを穿通して位置する際に前記ステープルのブリッジ部を嵌め合わせ式に受容するように構成された窪み部をプレートの上面に備える、請求項1記載の外科インプラント。
- プレートが下面に対して垂直な中央軸を有するとともに、プレートの上面に向かって開口しかつ前記中央軸に対して垂直にプレートの窪み部と交差しながらプレートを介して延在する1本あるいは複数の溝部をプレートがさらに備える請求項3記載の外科インプラント。
- ステープルのブリッジ部が実質的に正方形で4つのコーナ部を備えてなり、各コーナ部からそれぞれ1本の脚部が延在する請求項3記載の外科インプラント。
- ステープルのブリッジ部が実質的に円形であり、ステープルがブリッジ部から延在するとともにブリッジ部の周囲で均一な距離で離間して配置された少なくとも4本の脚部を有する請求項3記載の外科インプラント。
- ステープルの脚部に整合可能な複数のめくら穴をプレートが備える請求項1記載の外科インプラント。
- プレートの下面が荒目処理された表面あるいは三次元構造の表面を有する請求項1記載の外科インプラント。
- 脚部が荒目処理された表面あるいは三次元構造の表面を有する請求項1記載の外科インプラント。
- 前端部を有する外被部材と;
前記外被部材内に摺動可能に配置された打ち込みロッドと;
前記打ち込みロッドに固定されるとともに前記外被部材の外周面上に摺動可能に配置された打ち込みブロックを備えてなる器具を備え;
ブリッジ部と前記ブリッジ部から延在する複数の脚部を有する少なくとも1体のステープルを備え、前記ブリッジ部がそのブリッジ部を貫通して延在する中央開口部を有していて前記ステープルは前記器具の外被部材上でその外被部材の前端部から離間しかつ前記打ち込みブロックと整合させて配置可能であり従って前記打ち込みロッドを打撃することによって前記打ち込みブロックが前記ステープルを前記外被部材に沿ってその外被部材の前端部の方向に駆動することを誘起し;
また上面と下面を有してなる少なくとも1体のプレートを備え、前記プレートは、前記外被部材上に前記ステープルが配置されている際に前記プレートが前記ステープルから離間するように、柔軟組織を骨に対して保持するために前記プレートを前記器具によって操作することが可能であるように、ならびに前記ステープルの脚部が前記プレートを貫通して骨内に打ち込まれた際に前記ステープルがそのステープルのブリッジ部と柔軟組織の間に位置したプレートと共に骨に固定されるように、前記外被部材の前端部上に配置される、
ことからなる患者の骨に柔軟組織を固定するためのキット。 - プレートが外被部材の前端部を受容するための中央開口部を備える請求項10記載のキット。
- ステープルが引張強度TS1を有する材料からなり、プレートはステープルの引張強度TS1よりも低い引張強度TS2を有する材料からなり、従ってステープルの脚部がプレートを介して挿通可能である請求項10記載のキット。
- ステープルの脚部が前記プレートを挿通して位置する際に前記ステープルのブリッジ部を嵌め合わせ式に受容するように構成された窪み部をプレートの上面に備える請求項10記載のキット。
- プレートが下面に対して垂直な中央軸を有するとともに、プレートの上面に向かって開口しかつ前記中央軸に対して垂直にプレートの窪み部と交差しながらプレートを介して延在する1本あるいは複数の溝部をプレートがさらに備える請求項13記載のキット。
- ステープルのブリッジ部が実質的に正方形で4つのコーナ部を備えてなり、各コーナ部からそれぞれ1本の脚部が延在する請求項13記載のキット。
- ステープルのブリッジ部が実質的に円形であり、ステープルがブリッジ部から延在するとともにブリッジ部の周囲で均一な距離で離間して配置された少なくとも4本の脚部を有する請求項13記載のキット。
- ステープルとプレートが外被部材上に位置している際にステープルの脚部に整合可能な複数のめくら穴をプレートが備える請求項10記載のキット。
- ステープルとプレートが外被部材上に位置している際にステープルの脚部に整合可能な複数の穿孔をプレートが備える請求項10記載のキット。
- 打ち込みロッドがその縦軸に沿った通路を備える請求項10記載のキット。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41666810P | 2010-11-23 | 2010-11-23 | |
US61/416,668 | 2010-11-23 | ||
PCT/US2011/057885 WO2012071129A2 (en) | 2010-11-23 | 2011-10-26 | Surgical implant |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2014502862A JP2014502862A (ja) | 2014-02-06 |
JP6126010B2 true JP6126010B2 (ja) | 2017-05-10 |
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Family Applications (1)
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JP (1) | JP6126010B2 (ja) |
KR (1) | KR101890103B1 (ja) |
CN (1) | CN103179911B (ja) |
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CN103179911B (zh) | 2015-11-25 |
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BR112013007991A2 (pt) | 2016-06-28 |
US20160346023A1 (en) | 2016-12-01 |
KR20140022767A (ko) | 2014-02-25 |
CA2814948A1 (en) | 2012-05-31 |
AU2016210696A1 (en) | 2016-08-25 |
KR101890103B1 (ko) | 2018-08-22 |
WO2012071129A3 (en) | 2012-07-19 |
EP2642929A2 (en) | 2013-10-02 |
US10058366B2 (en) | 2018-08-28 |
WO2012071129A2 (en) | 2012-05-31 |
US20180036003A1 (en) | 2018-02-08 |
JP2014502862A (ja) | 2014-02-06 |
CN103179911A (zh) | 2013-06-26 |
BR112013007991B1 (pt) | 2020-08-25 |
TWI586310B (zh) | 2017-06-11 |
US10285743B2 (en) | 2019-05-14 |
TW201235005A (en) | 2012-09-01 |
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