JP6114439B2 - 匂い抑制物質の選択方法 - Google Patents

匂い抑制物質の選択方法 Download PDF

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Publication number
JP6114439B2
JP6114439B2 JP2016096146A JP2016096146A JP6114439B2 JP 6114439 B2 JP6114439 B2 JP 6114439B2 JP 2016096146 A JP2016096146 A JP 2016096146A JP 2016096146 A JP2016096146 A JP 2016096146A JP 6114439 B2 JP6114439 B2 JP 6114439B2
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Prior art keywords
odor
olfactory receptor
substance
target
receptor polypeptide
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Japanese (ja)
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JP2016224039A5 (enExample
JP2016224039A (ja
Inventor
敬一 吉川
敬一 吉川
菜穂子 齋藤
菜穂子 齋藤
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Kao Corp
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Kao Corp
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Priority to US15/576,514 priority Critical patent/US10738101B2/en
Priority to EP16803223.3A priority patent/EP3305898B1/en
Priority to PCT/JP2016/065656 priority patent/WO2016194788A1/ja
Publication of JP2016224039A publication Critical patent/JP2016224039A/ja
Publication of JP2016224039A5 publication Critical patent/JP2016224039A5/ja
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/40Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4005Detecting, measuring or recording for evaluating the nervous system for evaluating the sensory system
    • A61B5/4011Evaluating olfaction, i.e. sense of smell
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/10Screening for compounds of potential therapeutic value involving cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Neurology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Neurosurgery (AREA)
  • Physiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2016096146A 2015-05-29 2016-05-12 匂い抑制物質の選択方法 Active JP6114439B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US15/576,514 US10738101B2 (en) 2015-05-29 2016-05-27 Method for selecting odor-controlling substance
EP16803223.3A EP3305898B1 (en) 2015-05-29 2016-05-27 Method for selecting odor-controlling substance
PCT/JP2016/065656 WO2016194788A1 (ja) 2015-05-29 2016-05-27 匂い抑制物質の選択方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2015110390 2015-05-29
JP2015110390 2015-05-29

Publications (3)

Publication Number Publication Date
JP2016224039A JP2016224039A (ja) 2016-12-28
JP2016224039A5 JP2016224039A5 (enExample) 2017-02-09
JP6114439B2 true JP6114439B2 (ja) 2017-04-12

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ID=57748063

Family Applications (1)

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JP2016096146A Active JP6114439B2 (ja) 2015-05-29 2016-05-12 匂い抑制物質の選択方法

Country Status (3)

Country Link
US (1) US10738101B2 (enExample)
EP (1) EP3305898B1 (enExample)
JP (1) JP6114439B2 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6886893B2 (ja) * 2017-08-23 2021-06-16 花王株式会社 嗅覚受容体の応答測定方法
JP7197298B2 (ja) * 2018-07-17 2022-12-27 花王株式会社 メチルメルカプタン臭抑制剤の評価及び/又は選択方法
JP7385999B2 (ja) * 2019-05-24 2023-11-24 株式会社 資生堂 パーソナルケア組成物および悪臭抑制方法
WO2021235360A1 (ja) * 2020-05-18 2021-11-25 高砂香料工業株式会社 香料組成物および飲食品
WO2022270481A1 (ja) 2021-06-22 2022-12-29 花王株式会社 嗅覚受容体の発現方法及び応答測定方法
WO2023013792A1 (ja) * 2021-08-06 2023-02-09 味の素株式会社 目的の香気特性を有する物質のスクリーニング方法
CN113506596B (zh) * 2021-09-08 2022-11-15 汉王科技股份有限公司 嗅觉受体筛选、模型训练、酒类产品鉴定的方法与装置
JP2023084473A (ja) * 2021-12-07 2023-06-19 花王株式会社 フェノール化合物を原因とするにおいの抑制剤の評価及び/又は選択方法
JP2023084475A (ja) * 2021-12-07 2023-06-19 花王株式会社 カルボン酸を原因とするにおいの抑制剤の評価及び/又は選択方法
JP2023084478A (ja) * 2021-12-07 2023-06-19 花王株式会社 アルデヒドを原因とするにおいの抑制剤の評価及び/又は選択方法
CN116678995B (zh) * 2023-02-08 2025-11-14 汉王科技股份有限公司 嗅觉受体在识别4-乙基愈创木酚中的用途和检测4-乙基愈创木酚的方法
CN117741160B (zh) * 2023-12-21 2024-07-12 汉王科技股份有限公司 嗅觉受体在识别乙醇中的用途和检测乙醇的方法
CN118501118B (zh) * 2024-07-16 2024-10-29 汉王科技股份有限公司 一种基于细胞的生物荧光能量共振转移检测系统及应用
CN119601088B (zh) * 2024-11-18 2025-10-10 中国检验检疫科学研究院 一种马铃薯甲虫嗅觉受体基因筛选方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53121471A (en) 1977-03-31 1978-10-23 Nippon Chemical Ind Automatic position matching device
US7056948B2 (en) 2000-06-23 2006-06-06 Monell Chemical Senses Center Use of odor reducing and cross-adapting agents to reduce animal waste malodors
US7763238B2 (en) * 2002-01-16 2010-07-27 Monell Chemical Senses Center Olfactory adaptation and cross-adapting agents to reduce the perception of body odors
JP2005053887A (ja) * 2003-08-07 2005-03-03 Kao Corp 体臭に対する嗅覚の感度を低下させる方法
JP4966790B2 (ja) 2007-05-09 2012-07-04 長谷川香料株式会社 香料の評価方法
EP2806031B1 (en) * 2010-09-03 2016-11-02 Kao Corporation Method for searching for malodor control agent
JP5646255B2 (ja) 2010-09-03 2014-12-24 花王株式会社 悪臭抑制剤
JP5593271B2 (ja) 2011-06-06 2014-09-17 花王株式会社 悪臭抑制剤の探索方法
JP6104058B2 (ja) * 2013-06-03 2017-03-29 花王株式会社 カビ臭抑制剤の探索方法
JP6243698B2 (ja) 2013-10-22 2017-12-06 花王株式会社 フラネオールによるにおいの抑制剤

Also Published As

Publication number Publication date
EP3305898A4 (en) 2018-11-14
US20180127482A1 (en) 2018-05-10
JP2016224039A (ja) 2016-12-28
EP3305898A1 (en) 2018-04-11
US10738101B2 (en) 2020-08-11
EP3305898B1 (en) 2020-08-26

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