JP2016224039A5 - - Google Patents
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- Publication number
- JP2016224039A5 JP2016224039A5 JP2016096146A JP2016096146A JP2016224039A5 JP 2016224039 A5 JP2016224039 A5 JP 2016224039A5 JP 2016096146 A JP2016096146 A JP 2016096146A JP 2016096146 A JP2016096146 A JP 2016096146A JP 2016224039 A5 JP2016224039 A5 JP 2016224039A5
- Authority
- JP
- Japan
- Prior art keywords
- odor
- olfactory receptor
- target
- receptor polypeptide
- substance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001184 polypeptide Polymers 0.000 claims 56
- 108090000765 processed proteins & peptides Proteins 0.000 claims 56
- 102000004196 processed proteins & peptides Human genes 0.000 claims 56
- 102000012547 Olfactory receptors Human genes 0.000 claims 39
- 108050002069 Olfactory receptors Proteins 0.000 claims 39
- 239000000126 substance Substances 0.000 claims 36
- 238000000034 method Methods 0.000 claims 32
- 125000003275 alpha amino acid group Chemical group 0.000 claims 20
- 230000004044 response Effects 0.000 claims 12
- 231100000676 disease causative agent Toxicity 0.000 claims 10
- 210000002700 urine Anatomy 0.000 claims 10
- 241000208125 Nicotiana Species 0.000 claims 9
- 235000002637 Nicotiana tabacum Nutrition 0.000 claims 9
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 4
- 229910052791 calcium Inorganic materials 0.000 claims 4
- 239000011575 calcium Substances 0.000 claims 4
- 238000003384 imaging method Methods 0.000 claims 4
- 230000003834 intracellular effect Effects 0.000 claims 4
- 238000003571 reporter gene assay Methods 0.000 claims 4
- 230000001953 sensory effect Effects 0.000 claims 4
- 238000012286 ELISA Assay Methods 0.000 claims 3
- 238000003372 electrophysiological method Methods 0.000 claims 3
- 230000004043 responsiveness Effects 0.000 claims 2
- 238000002965 ELISA Methods 0.000 claims 1
- 230000006978 adaptation Effects 0.000 claims 1
- 235000019504 cigarettes Nutrition 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 102000005962 receptors Human genes 0.000 claims 1
- 108020003175 receptors Proteins 0.000 claims 1
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15/576,514 US10738101B2 (en) | 2015-05-29 | 2016-05-27 | Method for selecting odor-controlling substance |
| EP16803223.3A EP3305898B1 (en) | 2015-05-29 | 2016-05-27 | Method for selecting odor-controlling substance |
| PCT/JP2016/065656 WO2016194788A1 (ja) | 2015-05-29 | 2016-05-27 | 匂い抑制物質の選択方法 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015110390 | 2015-05-29 | ||
| JP2015110390 | 2015-05-29 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016224039A JP2016224039A (ja) | 2016-12-28 |
| JP2016224039A5 true JP2016224039A5 (enExample) | 2017-02-09 |
| JP6114439B2 JP6114439B2 (ja) | 2017-04-12 |
Family
ID=57748063
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016096146A Active JP6114439B2 (ja) | 2015-05-29 | 2016-05-12 | 匂い抑制物質の選択方法 |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US10738101B2 (enExample) |
| EP (1) | EP3305898B1 (enExample) |
| JP (1) | JP6114439B2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6886893B2 (ja) * | 2017-08-23 | 2021-06-16 | 花王株式会社 | 嗅覚受容体の応答測定方法 |
| JP7197298B2 (ja) * | 2018-07-17 | 2022-12-27 | 花王株式会社 | メチルメルカプタン臭抑制剤の評価及び/又は選択方法 |
| JP7385999B2 (ja) * | 2019-05-24 | 2023-11-24 | 株式会社 資生堂 | パーソナルケア組成物および悪臭抑制方法 |
| WO2021235360A1 (ja) * | 2020-05-18 | 2021-11-25 | 高砂香料工業株式会社 | 香料組成物および飲食品 |
| WO2022270481A1 (ja) | 2021-06-22 | 2022-12-29 | 花王株式会社 | 嗅覚受容体の発現方法及び応答測定方法 |
| WO2023013792A1 (ja) * | 2021-08-06 | 2023-02-09 | 味の素株式会社 | 目的の香気特性を有する物質のスクリーニング方法 |
| CN113506596B (zh) * | 2021-09-08 | 2022-11-15 | 汉王科技股份有限公司 | 嗅觉受体筛选、模型训练、酒类产品鉴定的方法与装置 |
| JP2023084473A (ja) * | 2021-12-07 | 2023-06-19 | 花王株式会社 | フェノール化合物を原因とするにおいの抑制剤の評価及び/又は選択方法 |
| JP2023084475A (ja) * | 2021-12-07 | 2023-06-19 | 花王株式会社 | カルボン酸を原因とするにおいの抑制剤の評価及び/又は選択方法 |
| JP2023084478A (ja) * | 2021-12-07 | 2023-06-19 | 花王株式会社 | アルデヒドを原因とするにおいの抑制剤の評価及び/又は選択方法 |
| CN116678995B (zh) * | 2023-02-08 | 2025-11-14 | 汉王科技股份有限公司 | 嗅觉受体在识别4-乙基愈创木酚中的用途和检测4-乙基愈创木酚的方法 |
| CN117741160B (zh) * | 2023-12-21 | 2024-07-12 | 汉王科技股份有限公司 | 嗅觉受体在识别乙醇中的用途和检测乙醇的方法 |
| CN118501118B (zh) * | 2024-07-16 | 2024-10-29 | 汉王科技股份有限公司 | 一种基于细胞的生物荧光能量共振转移检测系统及应用 |
| CN119601088B (zh) * | 2024-11-18 | 2025-10-10 | 中国检验检疫科学研究院 | 一种马铃薯甲虫嗅觉受体基因筛选方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS53121471A (en) | 1977-03-31 | 1978-10-23 | Nippon Chemical Ind | Automatic position matching device |
| US7056948B2 (en) | 2000-06-23 | 2006-06-06 | Monell Chemical Senses Center | Use of odor reducing and cross-adapting agents to reduce animal waste malodors |
| US7763238B2 (en) * | 2002-01-16 | 2010-07-27 | Monell Chemical Senses Center | Olfactory adaptation and cross-adapting agents to reduce the perception of body odors |
| JP2005053887A (ja) * | 2003-08-07 | 2005-03-03 | Kao Corp | 体臭に対する嗅覚の感度を低下させる方法 |
| JP4966790B2 (ja) | 2007-05-09 | 2012-07-04 | 長谷川香料株式会社 | 香料の評価方法 |
| EP2806031B1 (en) * | 2010-09-03 | 2016-11-02 | Kao Corporation | Method for searching for malodor control agent |
| JP5646255B2 (ja) | 2010-09-03 | 2014-12-24 | 花王株式会社 | 悪臭抑制剤 |
| JP5593271B2 (ja) | 2011-06-06 | 2014-09-17 | 花王株式会社 | 悪臭抑制剤の探索方法 |
| JP6104058B2 (ja) * | 2013-06-03 | 2017-03-29 | 花王株式会社 | カビ臭抑制剤の探索方法 |
| JP6243698B2 (ja) | 2013-10-22 | 2017-12-06 | 花王株式会社 | フラネオールによるにおいの抑制剤 |
-
2016
- 2016-05-12 JP JP2016096146A patent/JP6114439B2/ja active Active
- 2016-05-27 EP EP16803223.3A patent/EP3305898B1/en active Active
- 2016-05-27 US US15/576,514 patent/US10738101B2/en active Active
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