JP6042867B2 - 粘度の表現型が変化した糸状菌 - Google Patents

粘度の表現型が変化した糸状菌 Download PDF

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JP6042867B2
JP6042867B2 JP2014506564A JP2014506564A JP6042867B2 JP 6042867 B2 JP6042867 B2 JP 6042867B2 JP 2014506564 A JP2014506564 A JP 2014506564A JP 2014506564 A JP2014506564 A JP 2014506564A JP 6042867 B2 JP6042867 B2 JP 6042867B2
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gas1
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protein
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JP2014513530A (ja
JP2014513530A5 (https=
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ボディ、エリザベス・エー
セカンド、ロバート・ジェームス プラット
セカンド、ロバート・ジェームス プラット
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ダニスコ・ユーエス・インク
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/36—Adaptation or attenuation of cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
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  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
JP2014506564A 2011-04-22 2012-04-20 粘度の表現型が変化した糸状菌 Active JP6042867B2 (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201161478160P 2011-04-22 2011-04-22
US201161478162P 2011-04-22 2011-04-22
US61/478,162 2011-04-22
US61/478,160 2011-04-22
US201161480602P 2011-04-29 2011-04-29
US201161480610P 2011-04-29 2011-04-29
US201161480629P 2011-04-29 2011-04-29
US61/480,629 2011-04-29
US61/480,602 2011-04-29
US61/480,610 2011-04-29
PCT/US2012/034399 WO2012145592A1 (en) 2011-04-22 2012-04-20 Filamentous fungi having an altered viscosity phenotype

Publications (3)

Publication Number Publication Date
JP2014513530A JP2014513530A (ja) 2014-06-05
JP2014513530A5 JP2014513530A5 (https=) 2015-06-18
JP6042867B2 true JP6042867B2 (ja) 2016-12-14

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JP2014506564A Active JP6042867B2 (ja) 2011-04-22 2012-04-20 粘度の表現型が変化した糸状菌
JP2014506567A Active JP6042870B2 (ja) 2011-04-22 2012-04-20 粘度の表現型が変化した糸状菌
JP2014506566A Active JP6042869B2 (ja) 2011-04-22 2012-04-20 粘度の表現型が変化した糸状菌

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JP2014506567A Active JP6042870B2 (ja) 2011-04-22 2012-04-20 粘度の表現型が変化した糸状菌
JP2014506566A Active JP6042869B2 (ja) 2011-04-22 2012-04-20 粘度の表現型が変化した糸状菌

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Country Link
US (3) US9587242B2 (https=)
EP (3) EP2699668B1 (https=)
JP (3) JP6042867B2 (https=)
KR (3) KR101952467B1 (https=)
CN (3) CN103517981B (https=)
AU (4) AU2012245319A1 (https=)
BR (3) BR112013025434A2 (https=)
CA (3) CA2833756C (https=)
DK (3) DK2673290T3 (https=)
WO (3) WO2012145596A1 (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103517981B (zh) 2011-04-22 2017-02-15 丹尼斯科美国公司 具有粘度改变表型的丝状真菌
EP3000870B1 (en) * 2011-04-22 2018-01-24 Danisco US Inc. Filamentous fungi having an altered viscosity phenotype
CA2884573A1 (en) 2012-10-22 2014-05-01 Merck Sharp & Dohme Corp. Crz1 mutant fungal cells
WO2018226900A2 (en) 2017-06-06 2018-12-13 Zymergen Inc. A htp genomic engineering platform for improving fungal strains
EP3755710A1 (en) 2018-04-24 2020-12-30 Danisco US Inc. Filamentous fungal strains comprising reduced viscosity phenotypes
WO2019236848A1 (en) 2018-06-06 2019-12-12 Zymergen Inc. Manipulation of genes involved in signal transduction to control fungal morphology during fermentation and production
KR20210018354A (ko) * 2018-06-08 2021-02-17 에멀쥐 아이엔씨 진균성 균사체를 성장시키는 방법 및 식용 산물을 만드는 방법
JP7459509B2 (ja) 2018-07-30 2024-04-02 東レ株式会社 トリコデルマ属糸状菌の変異株およびタンパク質の製造方法
JP2021532775A (ja) * 2018-07-30 2021-12-02 ダニスコ・ユーエス・インク タンパク質生産性が強化された表現型を含む突然変異及び遺伝子改変糸状菌株並びにそれらの方法
BR112021006248A2 (pt) * 2018-10-11 2021-07-06 Toray Industries cepa mutante de trichoderma reesei e métodos para produzir uma proteína e para produzir uma celulase
US20200354756A1 (en) * 2019-04-03 2020-11-12 Danisco Us Inc Disruption of mvb12 in yeast is associated with increased alcohol production and tolerance
FR3104169B1 (fr) * 2019-12-04 2022-10-21 Ifp Energies Now Souche de champignon ayant une viscosite diminuee
AU2021219964A1 (en) * 2020-02-14 2022-09-29 Inbiose N.V. Production of glycosylated product in host cells
EP3926039A1 (en) 2020-06-17 2021-12-22 AB Enzymes GmbH Use of a nuclease for reducing the viscosity and/or preventing an increase in viscosity of a fermentation broth
US11479779B2 (en) 2020-07-31 2022-10-25 Zymergen Inc. Systems and methods for high-throughput automated strain generation for non-sporulating fungi
CN111944779B (zh) * 2020-08-28 2022-06-21 山东省科学院生物研究所 一种海藻糖合成双功能酶编码基因TvTPS/TPP及其应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI943133A0 (fi) * 1994-06-29 1994-06-29 Alko Ab Oy Transgena vaexter
US7189538B2 (en) 1999-03-24 2007-03-13 Genencor International, Inc. Hyphal growth in fungi
KR20020059350A (ko) 1999-07-30 2002-07-12 추후제출 재조합 단백질 생산용 숙주로서 아스페르길루스 소재의 용도
MXPA02010155A (es) * 2000-04-13 2004-08-19 Mark Aaron Emalfarb Nuevas secuencias reguladoras de expresion y productos de expresion en el campo de hongos filamentosos.
AU5354401A (en) * 2000-04-13 2001-10-30 Emalfarb, Mark Aaron High-throughput screening of expressed DNA libraries in filamentous fungi
AU2002303138A1 (en) 2001-03-14 2002-10-15 Genencor International, Inc. Regulatable growth of filamentous fungi
EP1502103B1 (en) * 2002-05-03 2006-09-13 DSM IP Assets B.V. Process for the monitoring of contaminant removal during the purification process of a pharmaceutical product produced by a host cell
EP1627049B1 (en) 2003-05-29 2010-02-17 Genencor International, Inc. Novel trichoderma genes
EP1689766B1 (en) * 2003-11-06 2012-04-25 Danisco US Inc. Expression in filamentous fungi of protease inhibitors and variants thereof
US20090117227A1 (en) * 2006-02-28 2009-05-07 Suntory Limited Gene encoding trehalose-6-phosphate phosphatase and use thereof
CA2808777C (en) * 2010-08-25 2019-10-29 Danisco Us Inc. Filamentous fungi having an altered viscosity phenotype
EP3000870B1 (en) 2011-04-22 2018-01-24 Danisco US Inc. Filamentous fungi having an altered viscosity phenotype
CN103517981B (zh) * 2011-04-22 2017-02-15 丹尼斯科美国公司 具有粘度改变表型的丝状真菌

Also Published As

Publication number Publication date
AU2012245323B2 (en) 2017-06-29
WO2012145592A1 (en) 2012-10-26
US20140315313A1 (en) 2014-10-23
EP2673290B1 (en) 2016-07-20
DK2699668T3 (en) 2018-02-26
CN103502266B (zh) 2016-10-19
US9593341B2 (en) 2017-03-14
CN103517981B (zh) 2017-02-15
JP2014513532A (ja) 2014-06-05
CN103502266A (zh) 2014-01-08
EP2699668A1 (en) 2014-02-26
BR112013025434A2 (pt) 2016-11-29
CA2833765C (en) 2021-05-11
AU2012245325B2 (en) 2017-05-25
JP6042870B2 (ja) 2016-12-14
EP2699667A1 (en) 2014-02-26
US9587242B2 (en) 2017-03-07
JP2014513530A (ja) 2014-06-05
DK2699667T3 (en) 2016-08-01
WO2012145598A1 (en) 2012-10-26
AU2012245323A1 (en) 2013-09-19
AU2017235968A1 (en) 2017-10-19
BR112013026535A2 (pt) 2016-11-29
BR112013026559A2 (pt) 2016-11-29
KR20140033046A (ko) 2014-03-17
AU2017235968B2 (en) 2018-07-05
CA2833765A1 (en) 2012-10-26
KR20140033049A (ko) 2014-03-17
JP2014513533A (ja) 2014-06-05
WO2012145596A1 (en) 2012-10-26
KR101952469B1 (ko) 2019-02-26
US20140220689A1 (en) 2014-08-07
DK2673290T3 (en) 2016-11-14
CA2833756A1 (en) 2012-10-26
CA2833539C (en) 2021-04-27
CA2833756C (en) 2021-06-22
EP2699667B1 (en) 2016-04-13
JP6042869B2 (ja) 2016-12-14
CN103502430B (zh) 2017-03-29
EP2699668B1 (en) 2017-11-29
US20140127817A1 (en) 2014-05-08
EP2673290A1 (en) 2013-12-18
US9868958B2 (en) 2018-01-16
KR20140033047A (ko) 2014-03-17
AU2012245325A1 (en) 2013-09-19
CN103517981A (zh) 2014-01-15
CA2833539A1 (en) 2012-10-26
CN103502430A (zh) 2014-01-08
AU2012245319A1 (en) 2013-08-22
KR101952467B1 (ko) 2019-02-26

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