JP6025329B2 - 精製済み間葉系幹細胞組成物および間葉系幹細胞組成物を精製する方法 - Google Patents

精製済み間葉系幹細胞組成物および間葉系幹細胞組成物を精製する方法 Download PDF

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JP6025329B2
JP6025329B2 JP2011523195A JP2011523195A JP6025329B2 JP 6025329 B2 JP6025329 B2 JP 6025329B2 JP 2011523195 A JP2011523195 A JP 2011523195A JP 2011523195 A JP2011523195 A JP 2011523195A JP 6025329 B2 JP6025329 B2 JP 6025329B2
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mesenchymal stem
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JP2012500214A (ja
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ダニルコビッチ，アラ
ニューマン，ロバート・イー
トム，サムソン
トン，クリストファー
ワング，ジャンリング
ヤング，ランダル
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メゾブラスト・インターナショナル・ソシエテ・ア・レスポンサビリテ・リミテ
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
JP2011523195A 2008-08-14 2009-08-14 精製済み間葉系幹細胞組成物および間葉系幹細胞組成物を精製する方法 Active JP6025329B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8889808P 2008-08-14 2008-08-14
US61/088,898 2008-08-14
PCT/US2009/053891 WO2010019886A1 (en) 2008-08-14 2009-08-14 Purified mesenchymal stem cell compositions and methods of purifying mesenchymal stem cell compositions

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JP2014224180A Division JP2015071610A (ja) 2008-08-14 2014-11-04 精製済み間葉系幹細胞組成物および間葉系幹細胞組成物を精製する方法

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JP2012500214A JP2012500214A (ja) 2012-01-05
JP6025329B2 true JP6025329B2 (ja) 2016-11-16

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JP2011523195A Active JP6025329B2 (ja) 2008-08-14 2009-08-14 精製済み間葉系幹細胞組成物および間葉系幹細胞組成物を精製する方法
JP2014224180A Pending JP2015071610A (ja) 2008-08-14 2014-11-04 精製済み間葉系幹細胞組成物および間葉系幹細胞組成物を精製する方法
JP2017000107A Pending JP2017081972A (ja) 2008-08-14 2017-01-04 精製済み間葉系幹細胞組成物および間葉系幹細胞組成物を精製する方法
JP2018036415A Pending JP2018109052A (ja) 2008-08-14 2018-03-01 精製済み間葉系幹細胞組成物および間葉系幹細胞組成物を精製する方法
JP2020072934A Active JP7580202B2 (ja) 2008-08-14 2020-04-15 精製済み間葉系幹細胞組成物および間葉系幹細胞組成物を精製する方法
JP2023000381A Pending JP2023052211A (ja) 2008-08-14 2023-01-05 精製済み間葉系幹細胞組成物および間葉系幹細胞組成物を精製する方法
JP2025086455A Pending JP2025122125A (ja) 2008-08-14 2025-05-23 精製済み間葉系幹細胞組成物および間葉系幹細胞組成物を精製する方法

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JP2014224180A Pending JP2015071610A (ja) 2008-08-14 2014-11-04 精製済み間葉系幹細胞組成物および間葉系幹細胞組成物を精製する方法
JP2017000107A Pending JP2017081972A (ja) 2008-08-14 2017-01-04 精製済み間葉系幹細胞組成物および間葉系幹細胞組成物を精製する方法
JP2018036415A Pending JP2018109052A (ja) 2008-08-14 2018-03-01 精製済み間葉系幹細胞組成物および間葉系幹細胞組成物を精製する方法
JP2020072934A Active JP7580202B2 (ja) 2008-08-14 2020-04-15 精製済み間葉系幹細胞組成物および間葉系幹細胞組成物を精製する方法
JP2023000381A Pending JP2023052211A (ja) 2008-08-14 2023-01-05 精製済み間葉系幹細胞組成物および間葉系幹細胞組成物を精製する方法
JP2025086455A Pending JP2025122125A (ja) 2008-08-14 2025-05-23 精製済み間葉系幹細胞組成物および間葉系幹細胞組成物を精製する方法

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US (6) US8637004B2 (enExample)
EP (3) EP3124601A1 (enExample)
JP (7) JP6025329B2 (enExample)
AR (2) AR073069A1 (enExample)
AU (1) AU2009281809B2 (enExample)
BR (1) BRPI0917993B8 (enExample)
CA (1) CA2733985C (enExample)
DK (1) DK2318519T3 (enExample)
ES (1) ES2608974T3 (enExample)
IL (1) IL211214A0 (enExample)
MX (2) MX362512B (enExample)
NZ (2) NZ602248A (enExample)
WO (1) WO2010019886A1 (enExample)
ZA (1) ZA201101858B (enExample)

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JP2020120671A (ja) 2020-08-13
EP4477742A2 (en) 2024-12-18
AU2009281809A1 (en) 2010-02-18
US20250312379A1 (en) 2025-10-09
JP2025122125A (ja) 2025-08-20
US20200197444A1 (en) 2020-06-25
BRPI0917993A2 (pt) 2017-10-10
JP2018109052A (ja) 2018-07-12
CA2733985A1 (en) 2010-02-18
US20230089901A1 (en) 2023-03-23
DK2318519T3 (en) 2017-01-16
ZA201101858B (en) 2011-11-30
EP3124601A1 (en) 2017-02-01
AR123811A2 (es) 2023-01-18
US20100068191A1 (en) 2010-03-18
JP2012500214A (ja) 2012-01-05
AU2009281809B2 (en) 2015-09-17
BRPI0917993B8 (pt) 2021-05-25
US20140105872A1 (en) 2014-04-17
JP2017081972A (ja) 2017-05-18
WO2010019886A1 (en) 2010-02-18
BRPI0917993B1 (pt) 2020-12-29
JP2023052211A (ja) 2023-04-11
ES2608974T3 (es) 2017-04-17
EP4477742A3 (en) 2025-02-26
JP7580202B2 (ja) 2024-11-11
EP2318519A1 (en) 2011-05-11
AR073069A1 (es) 2010-10-13
EP2318519B1 (en) 2016-10-05
NZ602248A (en) 2014-03-28
JP2015071610A (ja) 2015-04-16
MX362512B (es) 2019-01-22
US20180008642A1 (en) 2018-01-11
CA2733985C (en) 2016-07-12
EP2318519A4 (en) 2013-07-24
US8637004B2 (en) 2014-01-28
NZ591146A (en) 2012-10-26
IL211214A0 (en) 2011-04-28
MX2011001730A (es) 2011-03-24

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